Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy

Neurology

Volumn 50, Issue 5, 1998, Pages 1377-1882

  Kälviäinen, Reetta ^a   Salmenpera T ^b   Partanen, K ^b   Vainio, P ^b   Riekkinen, P ^b   Pitkanen A ^b  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN INJURY; CELL LOSS; CLINICAL ARTICLE; EPILEPTOGENESIS; FEMALE; HUMAN; MALE; MOSSY FIBER; NERVE SPROUTING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RECURRENT DISEASE; RELAXATION TIME; SEIZURE; SEIZURE THRESHOLD; TEMPORAL LOBE EPILEPSY;

EID: 0040449520     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.50.5.1377     Document Type: Article

References (26)

1. Babb T, Pretorius JK. Pathologic substrates of epilepsy. In: Wyllie E, ed. The treatment of epilepsy: principles and practice, 1st ed. Philadelphia: Lea & Febiger, 1993:55-70.
2. Represa A, Niquet J, Pollard H, Khrestchatisky M, Ben-Ari Y. From seizures to neo-synaptogenesis: intrinsic and extrinsic determinants of mossy fiber sprouting in the adult hippocampus. Hippocampus 1994;4:270-274.
3. Sloviter RS. The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy. Ann Neurol 1994;35:640-654.
4. Zola-Morgan S, Squire LR, Rempel NL, Clower RP, Amaral DG. Enduring memory impairment in monkeys after ischemic damage to the hippocampus. J Neurosci 1992;12:2582-2595.
5. Moser E, Moser M-B, Andersen P. Spatial learning impairment parallel the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions. J Neurosci 1993;13:3916-3925.
6. Cavazos J, Das I, Sutula T. Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures. J Neurosci 1994;14:3106-3121.
7. Mourizen-Dam A. Epilepsy and neuron loss in the hippocampus. Epilepsia 1980;21:617-629.
8. Mathern GW, Babb TL, Vickrey BG, Melendez M, Pretorius, JK. The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy. Brain 1995;118:105-118.
9. Cendes F, Andermann F, Gloor P, et al. Atrophy of mesial structures in patients with temporal lobe epilepsy: cause or consequence of repeated seizures? Ann Neurol 1993;4:795-801.
10. Kuzniecky RI, Burgard S, Bilir E, et al. Qualitative MRI segmentation in mesial temporal sclerosis: clinical correlations. Epilepsia 1996;37:433-439.
11. DeGiorgio CM, Tomiyasu U, Gott PS, Treiman DM. Hippocampal pyramidal cell loss in human status epilepticus. Epilepsia 1992;33:23-27.
12. Nohria V, Lee N, Tien RD, et al. Magnetic resonance imaging evidence of hippocampal sclerosis in progression: a case report. Epilepsia 1994;35:1332-1336.
13. During MJ, Spencer DD. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 1993;341:1607-1613.
14. DeGiorgio CM, Correale JD, Gott PS, et al. Serum neuron-specific enolase in human status epilepticus. Neurology 1995; 45:1134-1137.
15. Rabinowicz AL, Correale JD, Bracht KA, Smith TD, DeGiorgio CM. neuron-specific enolase is increased after non-convulsive status epilepticus. Epilepsia 1995;36(suppl 5):475-479.
16. Fazekas F, Kapeller P, Schmidt R, et al. Magnetic resonance imaging and spectroscopy findings after focal status epilepticus. Epilepsia 1995;36:946-949.
17. Soininen HS, Partanen K, Pitkänen A, et al. Volumetric MRI analysis of the amygdala and the hippocampus in subjects with age-associated memory impairment: correlation to visual and verbal memory. Neurology 1994;44:1660-1668.
18. Jackson GD, Connelly A, Duncan JS, Grunewald RA, Gadian DG. Detection of hippocampal pathology in intractable partial epilepsy. Increased sensitivity with quantitative magnetic resonance T2 relaxometry. Neurology 1993;43:1793-1799.
19. Cendes F, Andermann F, Gloor P, et al. MRI volumetric measurement of amygdala and hippocampus in temporal lobe epilepsy. Neurology 1993;43:719-725.
20. Van Paesschen W, Revesz T, Duncan JS, et al. Quantitative neuropathology and quantitative MRI of hippocampal sclerosis. Epilepsia 1994;35(suppl 8):19. Abstract.
21. Beach TG, Woodhurst WB, MacDonald DB, Jones MW. Reactive microglia in hippocampal sclerosis associated with human temporal lobe epilepsy. Neurosci Lett 1995:191:27-30.
22. Henry T, Drury I, Brunberg J, Pennell P, McKeever P, Beydoun A. Focal cerebral cerebral magnetic resonance changes associated with partial status epilepticus. Epilepsia 1994;35:35-41.
23. Yaffe K, Ferriero D, Barkovich J, Rowley H. Reversible MRI abnormalities following seizures. Neurology 1995;45:104-108.
24. Jackson GD, Grunewald RA, Connelly A, Duncan JS. Quantitative MR relaxometry study of effects of vigabatrin on the brains of patients with epilepsy. Epilepsy Res. 1994:18(suppl 2):127-137.
25. Kälviäinen R, Salmenperä T, Partanen K, et al. Prospective, quantitative MRI follow-up study of newly diagnosed epilepsy patients. Epilepsia 1996:37(suppl 4):152. Abstract.
26. Pitkänen A, Laakso M, Kälviäinen R, et al. Severity of hippocampal atrophy correlates with the prolongation of MRI T2 relaxation time in temporal lobe epilepsy but not in Alzheimer's disease. Neurology 1996;46:1724-1730.