메뉴 건너뛰기




Volumn 108, Issue 10, 2001, Pages 1439-1450

Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALPAIN; CATHEPSIN B; CHAPERONE; GLUTAMIC ACID; KAINIC ACID; OXYGEN REGULATED PROTEIN 150; UNCLASSIFIED DRUG;

EID: 0035184001     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI12978     Document Type: Article
Times cited : (131)

References (36)
  • 1
    • 0028198302 scopus 로고
    • Metabolic and biosynthetic alterations in cultured astrocytes exposed to hypoxia/reoxygenation
    • (1994) J. Neurochem. , vol.62 , pp. 1489-1495
    • Hori, O.1
  • 2
    • 0027940270 scopus 로고
    • Hypoxia-reoxygneation mediated induction of interleukin-6 in cultured rat astrocytes and expression in ischemic gerbil brain: A paracrine mechanism enhancing neuron-survival
    • (1994) J. Exp. Med. , vol.180 , pp. 2297-2308
    • Maeda, Y.1
  • 3
    • 0029915707 scopus 로고    scopus 로고
    • Purufucation and characterization of a novel stress protein, the 150 kDa oxygen regulated protein (ORP150), from cultured rat astrocytes, and its expression in ischemic mouse brain
    • (1996) J. Biol. Chem. , vol.279 , pp. 5025-5032
    • Kuwabara, K.1
  • 5
    • 0033525519 scopus 로고    scopus 로고
    • ORP150 (150 kDa oxygen-regulated protein) suppresses hypoxia-induced apoptotic cell death
    • (1999) J. Biol. Chem. , vol.274 , pp. 6397-6404
    • Ozawa, K.1
  • 6
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • (1999) Nat. Med. , vol.5 , pp. 101-106
    • Guo, Q.1
  • 9
    • 0028271350 scopus 로고
    • Glutamate-mediated injury in focal cerebral ischemia: The excitotoxin hypothesis revised
    • (1994) Brain Pathol. , vol.4 , pp. 23-36
    • Hossmann, K.A.1
  • 13
    • 0032980573 scopus 로고    scopus 로고
    • Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene
    • (1999) Mol. Cell Biol. , vol.19 , pp. 2366-2372
    • Harada, Y.N.1
  • 14
    • 0026099061 scopus 로고
    • PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model
    • (1991) Cell , vol.64 , pp. 217-227
    • Sasahara, M.1
  • 15
    • 0035108699 scopus 로고    scopus 로고
    • ORP150 protects against hypoxia/ischemia-induced neuronal death
    • (2001) Nature Med. , vol.7 , pp. 317-323
    • Tamatani, M.1
  • 16
    • 0032499277 scopus 로고    scopus 로고
    • Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice
    • (1998) Nature , vol.392 , pp. 601-605
    • Mulle, C.1
  • 17
    • 0345561544 scopus 로고    scopus 로고
    • Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NF-kB activation in primary hippocampal neurons
    • (1999) J. Biol. Chem. , vol.274 , pp. 8531-8538
    • Tamatani, M.1
  • 18
    • 0029961386 scopus 로고    scopus 로고
    • The 150 kDa oxygen regulated protein (ORP150) is expressed in human atherosclerotic plaques and allows mononuclear phagocytes to withstand cellular stress on exposure to hypoxi and modified LDL
    • (1996) J. Clin. Invest. , vol.98 , pp. 1930-1941
    • Tsukamoto, Y.1
  • 19
    • 0027718105 scopus 로고
    • Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
    • (1993) Am. J. Pathol. , vol.143 , pp. 1699-1712
    • Brett, J.1
  • 21
    • 0026784192 scopus 로고
    • Acetylcholine enhances NMDA-evoked calcium rise in hippocampal neurons
    • (1992) Brain Res. , vol.587 , pp. 83-87
    • Segal, M.1
  • 22
    • 0344603640 scopus 로고    scopus 로고
    • Glutathione depletion and neuronal cell death: The role of reactive oxygen intermediates and mitochondrial function
    • (1999) Brain Res. , vol.826 , pp. 53-62
    • Wullner, U.1
  • 24
    • 0032976738 scopus 로고    scopus 로고
    • Postictal blockade of ischemic hippocampal neuronal death in primates using selective cathepsin inhibitors
    • (1999) Exp. Neurol. , vol.155 , pp. 187-194
    • Tsuchiya, K.1
  • 26
    • 0034307558 scopus 로고    scopus 로고
    • Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals
    • (2000) J. Neurosci. , vol.20 , pp. 7183-7192
    • Tremblay, R.1
  • 27
    • 0034682414 scopus 로고    scopus 로고
    • Neurotoxicity induces cleavage of p35 to p25 by calpain
    • (2000) Nature , vol.405 , pp. 360-364
    • Lee, M.S.1
  • 29
    • 0031813589 scopus 로고    scopus 로고
    • Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells
    • (1998) J. Neurochem. , vol.71 , pp. 95-105
    • Tan, S.1    Wood, M.2    Maher, P.3
  • 30
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • (1999) Exp. Neurol. , vol.155 , pp. 302-314
    • Yu, Z.1    Luo, H.2    Fu, W.3    Mattson, M.P.4
  • 32
    • 0029042405 scopus 로고
    • 2+-binding protein with a carboxy-terminal NDEL sequence showed a partial homology with a 70-kDa heat shock protein (hsp70)
    • (1995) Cell Struc. Func. , vol.20 , pp. 133-141
    • Naved, A.F.1
  • 33
    • 0033933187 scopus 로고    scopus 로고
    • The 150 kDa oxygen regulated protein (ORP150) functions as a novel molecular chaperone in the protein transport of the MDCK cells
    • (2000) Am. J. Physiol. Cell Physiol. , vol.278
    • Bando, Y.1
  • 36
    • 0029001576 scopus 로고
    • A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-κB
    • (1995) EMBO J. , vol.14 , pp. 2580-2588
    • Pahl, H.L.1    Baeuerle, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.