In vivo role of caspases in excitotoxic neuronal death: Generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons

Molecular Brain Research

Volumn 108, Issue 1-2, 2002, Pages 18-32

  Tomioka, Masanori ^a,b   Shirotani, Keiro ^a   Iwata, Nobuhisa ^a   Lee, Hahn Jun ^a   Yang, Fusheng ^c   Cole, Greg M ^c   Seyama, Yousuke ^b,d   Saido, Takaomi C ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d OCHANOMIZU UNIVERSITY   (Japan)

Author keywords

Calpain; Caspase; Kainate; p35; Transgenic mouse

Indexed keywords

ACTIN; CALMODULIN DEPENDENT KINASE 2ALPHA; CALPAIN; CASPASE; CASPASE INHIBITOR; KAINIC ACID; PHOSPHOTRANSFERASE; PROTEIN P35; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; NEUROTOXIN; P35 PROTEIN, NUCLEOPOLYHEDROVIRUS; PROTEIN KINASE (CALCIUM,CALMODULIN); VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING; ANIMAL; CELL DEATH; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; MALE; METABOLISM; NERVE CELL; PHYSIOLOGY;

MUS MUSCULUS; UNIDENTIFIED BACULOVIRUS;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALPAIN; CASPASES; CELL DEATH; ENZYME ACTIVATION; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; MALE; MICE; MICE, TRANSGENIC; NEURONS; NEUROTOXINS; PROMOTER REGIONS (GENETICS); VIRAL PROTEINS;

EID: 0037121812     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00486-2     Document Type: Article

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