Increased Bcl-w expression following focally evoked limbic seizures in the rat

Neuroscience Letters

Volumn 305, Issue 3, 2001, Pages 153-156

  Henshall, David C ^a   Skradski, Shana L ^a   Lan, Jing Quan ^a   Ren, Tianbo ^a   Simon, Roger P ^a  

^a LEGACY RESEARCH   (United States)

Author keywords

Apoptosis; Bcl 2; Brain; Epilepsy; Kainic acid; Neuroprotection

Indexed keywords

DIAZEPAM; KAINIC ACID; PROTEIN; PROTEIN BCL W; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN NERVE CELL; BRAIN REGION; CELL DEATH; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AMYGDALA; ANIMALS; BLOTTING, WESTERN; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KAINIC ACID; LIMBIC SYSTEM; MICROINJECTIONS; NEURONS; OLFACTORY PATHWAYS; PROTEINS; RATS; SEIZURES;

EID: 0035877265     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01849-3     Document Type: Article

References (12)

1. Bcl-w, a novel member of the bcl-2 family, promotes cell survival
2. Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
3. Expression of the proto-oncogene bcl-2 is increased in the rat brain following kainate-induced seizures
4. Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system
5. Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy
6. Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures
7. Bcl-w expression is increased in brain regions affected by focal cerebral ischemia in the rat
8. Kainate-induced apoptotic cell death in hippocampal neurons
9. Bcl-2 family members in the development and degenerative pathologies of the nervous system
10. Status epilepticus-induced neuronal damage in the rat amygdaloid complex: Distribution, time-course and mechanisms
11. Overexpression of the cell death suppressor Bcl-w in ischemic brain: Implications for a neuroprotective role via the mitochondrial pathway