Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures

Neurobiology of Disease

Volumn 10, Issue 2, 2002, Pages 71-87

  Henshall, David C ^a   Skradski, Shana L ^a   Meller, Robert ^a   Araki, Tomohiro ^a   Minami, Manabu ^a   Schindler, Clara K ^a   Lan, Jing Quan ^a   Bonislawski, David P ^a   Simon, Roger P ^a  

^a LEGACY RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN ENZYME; CASPASE 6; CASPASE 7; KAINIC ACID; LAMIN A; UNCLASSIFIED DRUG; VALYLGLUTAMYLISOLEUCYLASPARTASE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CELL POPULATION; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ENZYME ACTIVATION; ENZYME ACTIVITY; EPILEPTIC DISCHARGE; HIPPOCAMPUS; IMMUNOREACTIVITY; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT;

EID: 0036077250     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.2002.0505     Document Type: Article

References (75)

1. Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis
2. Lamin and beta-tubulin fragmentation precede chromatin degradation in glutamate-induced neuronal apoptosis
3. Expression of Fas and Fas ligand after experimental traumatic brain injury in the rat
4. Injections of kainic acid into the amygdaloid complex of the rat: An electrographic, clinical and histological study in relation to the pathology of epilepsy
5. Specific caspase pathways are activated in the two stages of cerebral infarction
6. Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures
7. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes
8. Hippocampal sclerosis following brief generalized seizures in adulthood
9. Biochemical pathways of caspase activation during apoptosis
10. Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver
11. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
12. Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury
13. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
14. X-linked IAP is a direct inhibitor of cell-death proteases
15. ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis
16. Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
17. Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment
18. Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells
19. Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family
20. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
21. Differential c-Fos and caspase expression following kainic acid excitotoxicity
22. Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid- beta precursor protein and amyloidogenic A beta peptide formation
23. Activation of CPP32 protease in hippocampal neurons following ischemia and epilepsy
24. Dexamethasone pre-treatment interferes with apoptotic death in glioma cells
25. Apoptotic pathways: Paper wraps stone blunts scissors
26. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
27. Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
28. Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures
29. Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy
30. Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures
31. Formation of the Apaf-1/cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death
32. Cleavage of Bid may amplify caspase-8-induced neuronal death following focally evoked lim-bic seizures
33. Caspase-2 activation is redundant during seizure-induced neuronal death
34. Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: Evidence for a role for caspases and metalloproteinases
35. Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
36. Noncaspase proteases in apoptosis
37. Long term effects of refractory temporal lobe epilepsy on cognitive abilities: A cross-sectional study
38. Bilateral reductions of hippocampal volume, glucose metabolism, and wada hemispheric memory performance are related to the duration of mesial temporal lobe epilepsy
39. Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3
40. Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy
41. Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus
42. Release of caspase-9 from mito-chondria during neuronal apoptosis and cerebral ischemia
43. Expression of caspases and their substrates in the rat model of focal cerebral ischemia
44. Caspase-6 role in apoptosis of human neurons, amyloido-genesis, and Alzheimer's disease
45. Four deaths and a funeral: From caspases to alternative mechanisms
46. Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?
47. Necrotic death pathway in Fas receptor signaling
48. Fas receptor and neuronal cell death after spinal cord ischemia
49. Emerging therapeutic targets in caspase-dependent disease
50. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
51. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
52. ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
53. Chromatin condensation during apoptosis is accompanied by degradation of lamin A + B, without enhanced activation of cdc2 kinase
54. The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A
55. Alternative, nonsecretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8
56. Kainate-induced apoptotic cell death in hippocampal neurons
57. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
58. Hippocampal damage caused by seizures in temporal lobe epilepsy
59. Apoptosis in neurological disease
60. Caspases as treatment targets in stroke and neurodegenerative diseases
61. Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis
62. Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
63. X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes
64. Cleavage of lamin A by Mch2 alpha but not CPP32: Multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis
65. Long-term observation of rats after unilateral intra-amygdaloid injection of kainic acid
66. Neuroimaging evidence of progressive neuronal loss and dysfunction in temporal lobe epilepsy
67. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
68. Injections of picrotoxin and bicuculline into the amygdaloid complex of the rat: An electroencephalographic, behavioural and morphological analysis
69. The proteolytic procaspase activation network: An in vitro analysis
70. Caspase-8 and caspase-3 are expressed by different populations of cortical neurons undergoing delayed cell death after focal stroke in the rat
71. Apoptosis in caspase-inhibited neurons
72. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis
73. Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8
74. Caspases: Their intracellular localization and translocation during apoptosis