CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis- inducing ligand mediate ischemia-induced apoptosis in neurons

Journal of Neuroscience

Volumn 19, Issue 10, 1999, Pages 3809-3817

  Martin Villalba, Ana ^a   Herr, Ingrid ^b   Jeremias, Irmela ^b   Hahne, Michael ^d   Brandt, Roland ^a   Vogel, Johannes ^a   Schenkel, Johannes ^a   Herdegen, Thomas ^c   Debatin, Klaus Michael ^b,e  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

^e UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

Apoptosis; CD95 ligand; Focal ischemia; lpr mouse; Neurons; TRAIL

Indexed keywords

FAS ANTIGEN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; FEMALE; HUMAN; HUMAN CELL; LIGAND BINDING; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL DEGENERATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

EID: 0033562658     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-10-03809.1999     Document Type: Article

References (53)

1. Angel P, Hattori K, Smeal T, Karin M (1988) The jun protooncogene is positively autoregualted by its product Jun/AP-1. Cell 55:875-885.
2. Barone FC, Knudsen DJ, Nelson AH, Feuerstein GZ, Willette RN (1993) Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy. J Cereb Blood Flow Metab 13:683-692.
3. Becher B, D'Souza SD, Troutt AB, Antel JP (1998) Fas expression on human fetal astrocytes without susceptibility to Fas-mediated cytotoxicity. Neuroscience 84:627-634.
4. Bossy-Wetzel E, Bakiri L, Yaniv M (1997) Induction of apoptosis by the transcription factor c-Jun. EMBO J 16:1695-1709.
5. Brunner T, Yoo NJ, La Face D, Ware CF, Green DR (1996) Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. Int Immunol 8:1017-1026.
6. Chen Y-R, Meyer CF, Tan T-H (1996) Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ-radiation-induced apoptosis. J Biol Chem 271:631-634.
7. Connolly ES, Winfree CJ, Stern DM, Solomon RA, Pinsky DJ (1996) Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia. Neurosurgery 38:523-531.
8. Dawson VL, Dawson TM, London ED, Bredt DS, Snyder SH (1991) Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci USA 88:6368-6371.
9. Drake M, Friberg H, Boris-Möller F, Sakata K, Wieloch T (1996) The immunosuppressant FK506 ameliorates ischemic damage in the rat brain. Acta Physiol Scand 158:155-159.
10. Eilers A, Whitfield J, Babij C, Rubin LL, Ham J (1998) Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons. J Neurosci 18:1713-1724.
11. Eliason MJL, Sampei K, Mandir AS, Hurn PD, Traystman RJ, Bao J, Pieper A, Wang Z-Q, Dawson TM, Snyder SH, Dawson VL (1997) Poly (ADP-ribose)polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med 3:1089-1095.
12. Faris M, Kokot N, Latinis K, Kasibhatla S, Green DR, Koretzky GA, Nel A (1998) The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas Ligand expression. J Immunol 160:134-144.
13. French LE, Hahne M, Viard I, Radlgruber G, Zanone R, Becker K, Müller C, Tschopp J (1996) Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J Cell Biol 133:335-343.
14. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501.
15. Goillot E, Raingeaud J, Ranger A, Tepper RI, Davis RJ, Harlow E, Sanchez I (1997) Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway. Proc Natl Acad Sci USA 94:3302-3307.
16. Gold B (1997) FK506 and the role of immunophilins in nerve regeneration. Mol Neurobiol 15:285-306.
17. Ham J, Babij C, Whitfield J, Pfarr CM, Lallemand D, Zaniv M, Rubin LL (1995) A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14:927-939.
18. Herdegen T, Claret FX, Kallunki T, Martin-Villalba A, Winter C, Hunter T, Karin M (1998) Lasting N-terminal phosphorylation of c-Jun and activation of JNK/SAPK kinases following neuronal injury. J Neurosci 18:5124-5135.
19. Herr I, Balemans L, Böhler T, Walczak H, Debatin K-M (1996) Monitoring of CD95 (APO-1/Fas) ligand expression in human T cells by quantitative RT-PCR. Cell Death Differ 3:299-305.
20. Herr I, Wilhelm D, Böhler T, Angel P, Debatin K-M (1997) Activation of CD95 (APO-1/FAS) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J 16:6200-6208.
21. Hibi M, Lin A, Smeal T, Minden A, Karin M (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 7:2135-2148.
22. Jeremias I, Herr I, Boehler T, Debatin K-M (1998) TRAIL/APO-2-ligand-induced apoptosis in human T cells. Eur J Immunol 28:143-152.
23. Kallunki T, Deng TL, Hibi M, Karin M (1996) c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell 87:929-939.
24. Kasibhatla S, Brunner T, Genestier L, Echeverri F, Mahboubi A, Green DR (1998) DNA damaging agents induce expression of Fas-ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kB and AP-1. Mol Cell 1:543-551.
25. Knight R, Buxton DB (1996) Stimulation of c-Jun kinase and mitogen-activated protein kinase by ischemia and reperfusion in the perfused rat heart. Biochem Biophys Res Commun 218:83-88.
26. Kovary K, Bravo R (1991) Expression of different Jun and Fos proteins during the G0 to G1 transition in mouse fibroblasts: in vitro and in vivo associations. Mol Cell Biol 11:2451-2459.
27. Kraemer B, Wiegmann K, Kronke M (1995) Regulation of the human TNF promoter by the transcription factor Ets. J Biol Chem 270:6577-6583.
28. Kroemer G, Zamzami N, Susin SA (1997) Mitochondrial control of apoptosis. Immunol Today 18:44-51.
29. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad M, Avruch J, Woodgett RJ (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369:156-160.
30. Li Y, Chopp M, Jiang N, Zhang ZG, Zaloga C (1995) Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats. Stroke 26:1252-1258.
31. Lin TN, He YY, Wu G, Khan M, Hsu CY (1993) Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke 24:117-121.
32. Linnik MD, Zobrist RH, Hatfield MD (1993) Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24:2002-2008.
33. MacManus JP, Buchan AM, Hill IE, Rasquinha I, Preston E (1993) Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci Lett 164:89-92.
34. Matsuyama T, Hata T, Yamamoto Y, Tagaya M, Akita H, Uno H, Wanaka A, Furujama J-I, Sugita M (1995) Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization. Mol Brain Res 34:166-172.
35. Mizuno M, Yoshida J (1996) Tumor necrosis factor-α gene transfer augments anti-Fas antibody-mediated apoptosis in human glioma cells. Jpn J Cancer Res 87:543-547.
36. Nagata S (1997) Apoptosis by death factor. Cell 88:355-365.
37. Nakai A, Kuroda S, Kristian T, Siesjö BK (1997) The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat. Neurobiol Dis 4:288-300.
38. Onishi I, Tani T, Hashimoto T, Shimizu K, Yagi M, Yamamoto K, Yoshioka K (1997) Activation of c-Jun N-terminal kinase during ischemia and reperfusion in mouse liver. FEBS Lett 420:201-204.
39. Pleasure SJ, Page C, Lee VMY (1992) Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J Neurosci 12:1802-1815.
40. Saito K, Suyama K, Nishida K, Sei Y, Basile AS (1996) Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain. Neurosci Lett 206:149-152.
41. Schlingensiepen KH, Schlingensiepen R, Kunst M, Klinger I, Gerdes W, Seifert W, Brysch W (1993) Opposite functions of Jun-B and c-Jun in growth regulation and neuronal differentiation. Dev Genet 14:305-312.
42. Sharkey J, Butcher SP (1994) Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia. Nature 371:336-339.
43. Shibasaki F, Kondo E, Akagi T, McKeon F (1997) Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and bcl-2. Nature 386:728-731.
44. Snyder SH, Sabatini DM (1995) Immunophilins and the nervous system. Nat Med 1:32-37.
45. Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR (1990) A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab 10:290-293.
46. Vexler ZS, Roberts TPL, Bolen AW, Derugin N, Arieff AI (1997) Transient cerebral ischemia. J Clin Invest 99:1453-1459.
47. Virdee K, Bannister AJ, Hunt SP, Tolkovsky AM (1997) Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones. J Neurochem 69:550-561.
48. Vogel J, Möbius C, Kuschinsky W (1999) Early delineation of ischemic tissue in rat brain cryosection by high contrast staining. Stroke, in press.
49. von Reyher U, Strater J, Kittstein W, Gschwendt M, Krammer PH, Moller P (1998) Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis. Cancer Res 58:526-534.
50. Watson A, Eilers A, Lallemand D, Kyriakis J, Rubin LL, Ham J (1998) Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J Neurosci 18:751-762.
51. Wilson DJ, Fortner KA, Lynch DH, Mattingly RR, Macara IG, Posada JA, Budd RC (1996) JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. Eur J Immunol 26:989-994.
52. Yang DD, Kuan CY, Whitmarsh AJ, Rincon M, Zheng TS, Davis RJ, Rakic P, Flavell RA (1997) Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the JNK3 gene. Nature 289:865-870.
53. Zea Longa E, Weinstein PR, Carlson S, Cummis R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91.