메뉴 건너뛰기




Volumn 91, Issue 4, 1999, Pages 1461-1470

Bcl-2, Bax and Bcl-x expression following kainic acid administration at convulsant doses in the rat

Author keywords

Apoptosis; Bax; Bcl 2; Bcl x; Kainic acid; Necrosis

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

EID: 0344915157     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00704-0     Document Type: Article
Times cited : (54)

References (64)
  • 1
    • 0029056049 scopus 로고
    • Role of bcl-2 in the brain-derived neurotrophic factor survival response
    • Allsopp T.E., Kiselev S., Wyatt S., Davies A.M. Role of bcl-2 in the brain-derived neurotrophic factor survival response. Eur. J. Neurosci. 7:1995;1266-1272.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1266-1272
    • Allsopp, T.E.1    Kiselev, S.2    Wyatt, S.3    Davies, A.M.4
  • 2
    • 0027243086 scopus 로고
    • The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp T.E., Wyatts S., Paterson H.F., Davies A.M. The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell. 73:1993;295-307.
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatts, S.2    Paterson, H.F.3    Davies, A.M.4
  • 3
    • 0030614720 scopus 로고    scopus 로고
    • Immunolocalization of Bcl-xL/S in the central nervous system of neonatal and adult rats
    • Alonso G., Guillemain I., Dumoulin A., Privat A., Patey G. Immunolocalization of Bcl-xL/S in the central nervous system of neonatal and adult rats. Cell Tiss. Res. 288:1997;59-68.
    • (1997) Cell Tiss. Res. , vol.288 , pp. 59-68
    • Alonso, G.1    Guillemain, I.2    Dumoulin, A.3    Privat, A.4    Patey, G.5
  • 4
    • 0024384703 scopus 로고
    • Kainic acid-induced seizures: Potentiation by alpha-methyl-p-tyrosine
    • Baran H., Hortnagl H. Kainic acid-induced seizures: potentiation by alpha-methyl-p-tyrosine. Brain Res. 495:1989;253-260.
    • (1989) Brain Res. , vol.495 , pp. 253-260
    • Baran, H.1    Hortnagl, H.2
  • 5
    • 0018902044 scopus 로고
    • The role of epileptic activity in hippocampal and "remote" cerebral lesions induced by kainic acid
    • Ben-Ari Y., Tremblay E., Ottersen O.P., Meldrum B.S. The role of epileptic activity in hippocampal and "remote" cerebral lesions induced by kainic acid. Brain Res. 191:1980;79-87.
    • (1980) Brain Res. , vol.191 , pp. 79-87
    • Ben-Ari, Y.1    Tremblay, E.2    Ottersen, O.P.3    Meldrum, B.S.4
  • 8
    • 0028798574 scopus 로고
    • Bcl-2 is expressed in neurons that survive focal ischemia in the rat
    • Chen J., Graham S.H., Chan P.H., Lan J., Zho R.L., Simon R.P. bcl-2 is expressed in neurons that survive focal ischemia in the rat. NeuroReport. 6:1995;394-398.
    • (1995) NeuroReport , vol.6 , pp. 394-398
    • Chen, J.1    Graham, S.H.2    Chan, P.H.3    Lan, J.4    Zho, R.L.5    Simon, R.P.6
  • 10
    • 0029884441 scopus 로고    scopus 로고
    • Expression of the apoptosis-effector gene bax is up-regulated in vulnerable hippocampal neurons following global ischemia
    • Chen J., Zhu R.L., Nakayama M., Kawaguchi K., Jin K., Stetler R.A., Simon R.P., Graham S.H. Expression of the apoptosis-effector gene bax is up-regulated in vulnerable hippocampal neurons following global ischemia. J. Neurochem. 67:1996;64-71.
    • (1996) J. Neurochem. , vol.67 , pp. 64-71
    • Chen, J.1    Zhu, R.L.2    Nakayama, M.3    Kawaguchi, K.4    Jin, K.5    Stetler, R.A.6    Simon, R.P.7    Graham, S.H.8
  • 11
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Choczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt. Biochem. 162:1987;156-159.
    • (1987) Analyt. Biochem. , vol.162 , pp. 156-159
    • Choczynski, P.1    Sacchi, N.2
  • 12
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 13
    • 0019297292 scopus 로고
    • Cerebral metabolic response to systemic kainic acid: 14-C-deoxyglucose studies
    • Collins R.C., McLean M., Olney J. Cerebral metabolic response to systemic kainic acid: 14-C-deoxyglucose studies. Life Sci. 27:1980;855-862.
    • (1980) Life Sci. , vol.27 , pp. 855-862
    • Collins, R.C.1    McLean, M.2    Olney, J.3
  • 14
    • 0029052332 scopus 로고
    • The Bcl-2 family of proteins, and the regulation of cell survival
    • Davies J.C. The Bcl-2 family of proteins, and the regulation of cell survival. Trends Neurosci. 18:1995;355-358.
    • (1995) Trends Neurosci. , vol.18 , pp. 355-358
    • Davies, J.C.1
  • 17
    • 0031808675 scopus 로고    scopus 로고
    • Bcl-2, Bax and Bcl-x expression in the CA1 area of the hippocampus following transient forebrain ischemia in the adult gerbil
    • Ferrer I., López E., Blanco R., Rivera R., Ballabriga J., Pozas E., Martí E. Bcl-2, Bax and Bcl-x expression in the CA1 area of the hippocampus following transient forebrain ischemia in the adult gerbil. Expl Brain Res. 121:1998;167-173.
    • (1998) Expl Brain Res. , vol.121 , pp. 167-173
    • Ferrer, I.1    López, E.2    Blanco, R.3    Rivera, R.4    Ballabriga, J.5    Pozas, E.6    Martí, E.7
  • 19
    • 0030806650 scopus 로고    scopus 로고
    • Bcl-2, Bax and Bcl-x expression following ischemia in the infant rat brain
    • Ferrer I., Pozas E., López E., Ballabriga J. Bcl-2, Bax and Bcl-x expression following ischemia in the infant rat brain. Acta neuropath. 94:1997;583-589.
    • (1997) Acta Neuropath. , vol.94 , pp. 583-589
    • Ferrer, I.1    Pozas, E.2    López, E.3    Ballabriga, J.4
  • 20
    • 0027941085 scopus 로고
    • Increased expression of bcl-2 immunoreactivity in the developing cerebral cortex of the rat
    • Ferrer I., Tortosa A., Condom E., Blanco R., Macaya A., Planas A.M. Increased expression of bcl-2 immunoreactivity in the developing cerebral cortex of the rat. Neurosci. Lett. 179:1994;13-16.
    • (1994) Neurosci. Lett. , vol.179 , pp. 13-16
    • Ferrer, I.1    Tortosa, A.2    Condom, E.3    Blanco, R.4    Macaya, A.5    Planas, A.M.6
  • 21
    • 0027931560 scopus 로고
    • DNA fragmentation in rat brain after intraperitoneal administration of kainate
    • Filipkowski R., Hetman M., Kaminska B., Kaczmare K.L. DNA fragmentation in rat brain after intraperitoneal administration of kainate. NeuroReport. 5:1994;1538-1540.
    • (1994) NeuroReport , vol.5 , pp. 1538-1540
    • Filipkowski, R.1    Hetman, M.2    Kaminska, B.3    Kaczmare, K.L.4
  • 23
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
    • García I., Martinou I., Tsujimoto Y., Martinou J.C. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science. 258:1992;302-304.
    • (1992) Science , vol.258 , pp. 302-304
    • García, I.1    Martinou, I.2    Tsujimoto, Y.3    Martinou, J.C.4
  • 24
    • 0027284098 scopus 로고
    • Spatiotemporal induction of immediate early genes in the rat brain after limbic seizures: Effects of NMDA receptor antagonist MK-801
    • Gass P., Herdegen T., Bravo R., Miessling M. Spatiotemporal induction of immediate early genes in the rat brain after limbic seizures: effects of NMDA receptor antagonist MK-801. Eur. J. Neurosci. 5:1993;933-943.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 933-943
    • Gass, P.1    Herdegen, T.2    Bravo, R.3    Miessling, M.4
  • 26
    • 0029091740 scopus 로고
    • Role of bcl-2 in the survival and function of developing and mature sympathetic neurons
    • Greenlund L. J. S., Korsmeyer S. J. and Johnson E. M. Jr. (1995) Role of bcl-2 in the survival and function of developing and mature sympathetic neurons. Neuron 15, 649-41.
    • (1995) Neuron , vol.15 , pp. 649-741
    • Greenlund, L.J.S.1    Korsmeyer, S.J.2    Johnson E.M., Jr.3
  • 27
    • 0027380517 scopus 로고
    • Pharmacological manipulation of the NMDA receptor differentially protects from systemic kainic acid neuropathology: Evaluation through ornithine decarboxylase induction, morphology and GFAP immunohistochemistry
    • Guarnieri T., Virgili M., Villaui L., Facchienetti F., Coutestabile A., Migani P. Pharmacological manipulation of the NMDA receptor differentially protects from systemic kainic acid neuropathology: evaluation through ornithine decarboxylase induction, morphology and GFAP immunohistochemistry. Restor. Neur. Neurosci. 5:1993;327-335.
    • (1993) Restor. Neur. Neurosci. , vol.5 , pp. 327-335
    • Guarnieri, T.1    Virgili, M.2    Villaui, L.3    Facchienetti, F.4    Coutestabile, A.5    Migani, P.6
  • 28
    • 0029001403 scopus 로고
    • Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
    • Guillardon F., Wichert H., Zimmermann M. Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Neurosci. Lett. 192:1995;85-88.
    • (1995) Neurosci. Lett. , vol.192 , pp. 85-88
    • Guillardon, F.1    Wichert, H.2    Zimmermann, M.3
  • 29
    • 0029879631 scopus 로고    scopus 로고
    • Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia
    • Hara A., Iwai T., Niwa M., Vematsu T., Yoshimi N., Tanaka T., Mori H. Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia. Brain Res. 711:1996;249-253.
    • (1996) Brain Res. , vol.711 , pp. 249-253
    • Hara, A.1    Iwai, T.2    Niwa, M.3    Vematsu, T.4    Yoshimi, N.5    Tanaka, T.6    Mori, H.7
  • 30
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenberry D., Nuñez G., Milliam C., Schreiber R.D., Korsmeyer S.J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 348:1990;334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenberry, D.1    Nuñez, G.2    Milliam, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 31
    • 0030963602 scopus 로고    scopus 로고
    • Cytosol-to-membrane redistribution of Bax and Bcl-xL during apoptosis
    • Hsu Y., Wolter K. G., Youle R. J. (1997) Cytosol-to-membrane redistribution of Bax and Bcl-xL during apoptosis. Proc. natn. Acad. Sci. U.S.A. 94, 3688-72.
    • (1997) Proc. Natn. Acad. Sci. U.S.A. , vol.94 , pp. 3688-3772
    • Hsu, Y.1    Wolter, K.G.2    Youle, R.J.3
  • 32
    • 0031983648 scopus 로고    scopus 로고
    • Differential regulation of Bax, Bcl-2, and Bcl-x proteins in focal cortical ischemia in the rat
    • Isenmann S., Stoll G., Schroeter M., Krajewski S., Reed J.C., Bahr M. Differential regulation of Bax, Bcl-2, and Bcl-x proteins in focal cortical ischemia in the rat. Brain Path. 8:1998;49-62.
    • (1998) Brain Path. , vol.8 , pp. 49-62
    • Isenmann, S.1    Stoll, G.2    Schroeter, M.3    Krajewski, S.4    Reed, J.C.5    Bahr, M.6
  • 33
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogene regulators of cell death
    • Korsmeyer S.J. Bcl-2 initiates a new category of oncogene regulators of cell death. Blood. 80:1992;879-886.
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 34
    • 0028036895 scopus 로고
    • Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2
    • Krajewski S., Krajewska M., Shabaik A., Miyashita T., Wang H.G., Reed J.C. Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Am. J. Path. 145:1994;1323-1336.
    • (1994) Am. J. Path. , vol.145 , pp. 1323-1336
    • Krajewski, S.1    Krajewska, M.2    Shabaik, A.3    Miyashita, T.4    Wang, H.G.5    Reed, J.C.6
  • 36
    • 0019501929 scopus 로고
    • Kainic acid-induced limbic motor seizures: Metabolic, behavioral, electroencephalographic and neuropathological correlates
    • Lothman E.W., Collins R.C. Kainic acid-induced limbic motor seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain Res. 218:1981;299-318.
    • (1981) Brain Res. , vol.218 , pp. 299-318
    • Lothman, E.W.1    Collins, R.C.2
  • 39
    • 0028178385 scopus 로고
    • Bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS
    • Merry D.E., Veis D.J., Hickey W.F., Korsmeyer S.J. Bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development. 130:1994;301-311.
    • (1994) Development , vol.130 , pp. 301-311
    • Merry, D.E.1    Veis, D.J.2    Hickey, W.F.3    Korsmeyer, S.J.4
  • 40
    • 0031057656 scopus 로고    scopus 로고
    • Bcl-2 gene family in the nervous system
    • Merry D.E., Korsmeyer S.J. Bcl-2 gene family in the nervous system. A. Rev. Neurosci. 20:1997;245-267.
    • (1997) A. Rev. Neurosci. , vol.20 , pp. 245-267
    • Merry, D.E.1    Korsmeyer, S.J.2
  • 41
    • 1842456916 scopus 로고    scopus 로고
    • Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development
    • Michaelidis T.M., Sendtner M., Cooper J.D., Airaksinen M.S., Hotmann B. Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron. 17:1996;75-89.
    • (1996) Neuron , vol.17 , pp. 75-89
    • Michaelidis, T.M.1    Sendtner, M.2    Cooper, J.D.3    Airaksinen, M.S.4    Hotmann, B.5
  • 42
    • 0029874986 scopus 로고    scopus 로고
    • Bcl-x(s) antagonizes the protective effects of Bcl-x(l)
    • Minn A.J., Boise L.H., Thompson C.B. Bcl-x(s) antagonizes the protective effects of Bcl-x(l). J. biol. Chem. 271:1996;6306-6312.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6306-6312
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 43
    • 0027261312 scopus 로고
    • N-methyl-D-aspartate receptor agonists decrease proto-oncogene bcl-2 mRNA expression in cultured rat cerebellum granule neurons
    • Montpied P., Weller M., Paul S.M. N-methyl-D-aspartate receptor agonists decrease proto-oncogene bcl-2 mRNA expression in cultured rat cerebellum granule neurons. Biochem. biophys. Res. Commun. 195:1993;623-629.
    • (1993) Biochem. Biophys. Res. Commun. , vol.195 , pp. 623-629
    • Montpied, P.1    Weller, M.2    Paul, S.M.3
  • 45
    • 0028175759 scopus 로고
    • Targeted disruption of bcl-2ab in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • Nakayama K., Nakayama K.I., Negishi I., Kuida K., Sawa H., Loh D.Y. Targeted disruption of bcl-2ab in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc. natn. Acad. Sci. U.S.A. 91:1994;3700-3704.
    • (1994) Proc. Natn. Acad. Sci. U.S.A. , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Nakayama, K.I.2    Negishi, I.3    Kuida, K.4    Sawa, H.5    Loh, D.Y.6
  • 46
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 48
    • 0029072690 scopus 로고
    • Evidence for apoptotic cell death in Huntington's disease and excitotoxic animal models
    • Portera-Cailliau C., Hedreen J., Rice D., Koliatos V. Evidence for apoptotic cell death in Huntington's disease and excitotoxic animal models. J. Neurosci. 15:1995;3775-3787.
    • (1995) J. Neurosci. , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.2    Rice, D.3    Koliatos, V.4
  • 49
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed J.C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124:1994;1-6.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 50
    • 0029915860 scopus 로고    scopus 로고
    • Apoptosis of bcl-x deficient telencephalic cells in vitro
    • Roth K.A., Motoyama N., Loh D. Apoptosis of bcl-x deficient telencephalic cells in vitro. J. Neurosci. 16:1996;1753-1758.
    • (1996) J. Neurosci. , vol.16 , pp. 1753-1758
    • Roth, K.A.1    Motoyama, N.2    Loh, D.3
  • 51
    • 0026513647 scopus 로고
    • Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage
    • Sacaan A.I., Shoepp D.D. Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage. Neurosci. Lett. 139:1992;77-82.
    • (1992) Neurosci. Lett. , vol.139 , pp. 77-82
    • Sacaan, A.I.1    Shoepp, D.D.2
  • 53
    • 0018862109 scopus 로고
    • Widespread patterns of neuronal damage following systemic or intracerebral injection of kainic acid: A histological study
    • Schwob J.E., Fuller T., Rice J.L., Olney J.W. Widespread patterns of neuronal damage following systemic or intracerebral injection of kainic acid: a histological study. Neuroscience. 5:1980;991-1014.
    • (1980) Neuroscience , vol.5 , pp. 991-1014
    • Schwob, J.E.1    Fuller, T.2    Rice, J.L.3    Olney, J.W.4
  • 56
    • 84886639406 scopus 로고
    • Kainic acid induced seizures: Dose-relationship of behavioural, neurochemical and histopathological changes
    • Sperck G., Lassman H., Baran H., Seitelberger F., Hornykiewicz O. Kainic acid induced seizures: dose-relationship of behavioural, neurochemical and histopathological changes. Brain Res. 338:1985;289-295.
    • (1985) Brain Res. , vol.338 , pp. 289-295
    • Sperck, G.1    Lassman, H.2    Baran, H.3    Seitelberger, F.4    Hornykiewicz, O.5
  • 57
    • 0026687022 scopus 로고
    • The biochemical mechanisms of the excitotoxicity of kainic acid
    • Sun A.Y., Cheng Y., Bu Q., Oldfield F. The biochemical mechanisms of the excitotoxicity of kainic acid. Molec. chem. Neuropath. 17:1992;51-63.
    • (1992) Molec. Chem. Neuropath. , vol.17 , pp. 51-63
    • Sun, A.Y.1    Cheng, Y.2    Bu, Q.3    Oldfield, F.4
  • 58
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis D.J., Sorenson C.M., Shutter J.R., Korsmeyer S.J. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell. 75:1993;229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 59
    • 0031001244 scopus 로고    scopus 로고
    • Bax promotes neuronal cell death and is downregulated during the development of the nervous system
    • Vekrellis K., McCarthy M.J., Watson A., Whitfield J., Rubin L.L., Ham J. Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development. 124:1997;1239-1249.
    • (1997) Development , vol.124 , pp. 1239-1249
    • Vekrellis, K.1    McCarthy, M.J.2    Watson, A.3    Whitfield, J.4    Rubin, L.L.5    Ham, J.6
  • 61
    • 0025810536 scopus 로고
    • Cloning of a putative high affinity kainate receptor expressed predominantly in hippocampal CA3 cells
    • Werner P., Voigt M., Kainänen K., Wisden W., Seeburg H. Cloning of a putative high affinity kainate receptor expressed predominantly in hippocampal CA3 cells. Nature. 351:1991;742-744.
    • (1991) Nature , vol.351 , pp. 742-744
    • Werner, P.1    Voigt, M.2    Kainänen, K.3    Wisden, W.4    Seeburg, H.5
  • 62
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerisation with Bax
    • Yin X.M., Oltvai Z.N., Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerisation with Bax. Nature. 369:1994;321-323.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 63
    • 0029917541 scopus 로고    scopus 로고
    • Proapoptotic protein Bax heterodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
    • Zha H., Aima-Sempe C., Sato T., Reed J.C. Proapoptotic protein Bax heterodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2. J. biol. Chem. 271:1996;7440-7444.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7440-7444
    • Zha, H.1    Aima-Sempe, C.2    Sato, T.3    Reed, J.C.4
  • 64
    • 0027304383 scopus 로고
    • Bcl-2 blocks glutamate toxicity in neural cell lines
    • Zhong L.T., Hane D.J., Bredesen D.E. Bcl-2 blocks glutamate toxicity in neural cell lines. Molec. Brain Res. 19:1993;353-355.
    • (1993) Molec. Brain Res. , vol.19 , pp. 353-355
    • Zhong, L.T.1    Hane, D.J.2    Bredesen, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.