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Volumn 25, Issue 3, 2005, Pages 183-213

iNKT-cell responses to glycolipids

Author keywords

CD1d; Glycolipids; Immunomodulation; Immunotherapy; Innate immunity; Natural killer T cells

Indexed keywords

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CD28 ANTIGEN; CD40 LIGAND; CERAMIDE DERIVATIVE; CYTOKINE; DNA VACCINE; ESTRADIOL; GALACTOSYLCERAMIDE; GAMMA INTERFERON ANTIBODY; GANGLIOSIDE GD3; GLYCOLIPID; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 7; MANNOSIDE; OCH; OXAZOLONE; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

EID: 26844503175     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevImmunol.v25.i3.20     Document Type: Review
Times cited : (52)

References (207)
  • 1
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 2002; 296:301-305.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 2
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon DT, Locksley RM. The instructive role of innate immunity in the acquired immune response. Science 1996; 272:50-53.
    • (1996) Science , vol.272 , pp. 50-53
    • Fearon, D.T.1    Locksley, R.M.2
  • 3
    • 0030890603 scopus 로고    scopus 로고
    • Mouse CD1-specific NK1 T cells: Development, specificity, and function
    • Bendelac A, Rivera MN, Park SH, Roark JH. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu Rev Immunol 1997; 15:535-562.
    • (1997) Annu Rev Immunol , vol.15 , pp. 535-562
    • Bendelac, A.1    Rivera, M.N.2    Park, S.H.3    Roark, J.H.4
  • 4
    • 0035083625 scopus 로고    scopus 로고
    • CD1d and natural T cells: How their properties jump-start the immune system
    • Joyce S. CD1d and natural T cells: how their properties jump-start the immune system. Cell Mol Life Sci 2001; 58:442-469.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 442-469
    • Joyce, S.1
  • 5
    • 0038228956 scopus 로고    scopus 로고
    • The regulatory role of Vα14 NKT cells in innate and acquired immune response
    • Taniguchi M, Harada M, Kojo S, Nakayama T, Wakao H. The regulatory role of Vα14 NKT cells in innate and acquired immune response. Annu Rev Immunol 2003; 21:483-513.
    • (2003) Annu Rev Immunol , vol.21 , pp. 483-513
    • Taniguchi, M.1    Harada, M.2    Kojo, S.3    Nakayama, T.4    Wakao, H.5
  • 6
    • 3042760542 scopus 로고    scopus 로고
    • Regulation of immune responses by CD1d-restricted natural killer T cells
    • Van Kaer L. Regulation of immune responses by CD1d-restricted natural killer T cells. Immunol Res 2004; 30:139-153.
    • (2004) Immunol Res , vol.30 , pp. 139-153
    • Van Kaer, L.1
  • 7
    • 2542448243 scopus 로고    scopus 로고
    • CD1: Antigen presentation and T cell function
    • Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annu Rev Immunol 2004; 22:817-890.
    • (2004) Annu Rev Immunol , vol.22 , pp. 817-890
    • Brigl, M.1    Brenner, M.B.2
  • 8
    • 10044286529 scopus 로고    scopus 로고
    • Going both ways: Immune regulation via CD1d-dependent NKT cells
    • Godfrey DI, Kronenberg M. Going both ways: immune regulation via CD1d-dependent NKT cells. J Clin Invest 2004; 114:1379-1388.
    • (2004) J Clin Invest , vol.114 , pp. 1379-1388
    • Godfrey, D.I.1    Kronenberg, M.2
  • 9
    • 17144374753 scopus 로고    scopus 로고
    • Toward an understanding of NKT cell biology: Progress and paradoxes
    • Kronenberg M. Toward an understanding of NKT cell biology: progress and paradoxes. Annu Rev Immunol 2005; 26:877-900.
    • (2005) Annu Rev Immunol , vol.26 , pp. 877-900
    • Kronenberg, M.1
  • 11
    • 0035753991 scopus 로고    scopus 로고
    • Autoreactivity by design: Innate B and T lymphocytes
    • Bendelac A, Bonneville M, Kearney JF. Autoreactivity by design: innate B and T lymphocytes. Nat Rev Immunol 2001; 1:177-186.
    • (2001) Nat Rev Immunol , vol.1 , pp. 177-186
    • Bendelac, A.1    Bonneville, M.2    Kearney, J.F.3
  • 13
    • 0034680109 scopus 로고    scopus 로고
    • CD1-restricted T-cell responses and microbial infection
    • Park SH, Bendelac A. CD1-restricted T-cell responses and microbial infection. Nature 2000; 406:788-792.
    • (2000) Nature , vol.406 , pp. 788-792
    • Park, S.H.1    Bendelac, A.2
  • 14
    • 0035424975 scopus 로고    scopus 로고
    • CD1-specific T cells in microbial immunity
    • Gumperz JE, Brenner MB. CD1-specific T cells in microbial immunity. Curr Opin Immunol 2001; 13:471-480.
    • (2001) Curr Opin Immunol , vol.13 , pp. 471-480
    • Gumperz, J.E.1    Brenner, M.B.2
  • 15
    • 0141446179 scopus 로고    scopus 로고
    • Role of CD1d-restricted NKT cells in microbial immunity
    • Skold M, Behar SM. Role of CD1d-restricted NKT cells in microbial immunity. Infect Immun 2003; 71:5447-5455.
    • (2003) Infect Immun , vol.71 , pp. 5447-5455
    • Skold, M.1    Behar, S.M.2
  • 16
    • 18044398195 scopus 로고    scopus 로고
    • The role of group 1 and group 2 CD1-restricted T cells in microbial immunity
    • Skold M, Behar SM. The role of group 1 and group 2 CD1-restricted T cells in microbial immunity. Microbes Infect 2005; 7:544-551.
    • (2005) Microbes Infect , vol.7 , pp. 544-551
    • Skold, M.1    Behar, S.M.2
  • 17
    • 0036008999 scopus 로고    scopus 로고
    • Natural killer T (NKT) cells and their role in antitumor immunity
    • Brutkiewicz RR, Sriram V. Natural killer T (NKT) cells and their role in antitumor immunity. Crit Rev Oncol Hematol 2002; 41:287-298.
    • (2002) Crit Rev Oncol Hematol , vol.41 , pp. 287-298
    • Brutkiewicz, R.R.1    Sriram, V.2
  • 19
    • 0034572835 scopus 로고    scopus 로고
    • NKT cells and tumor immunity-a double-edged sword
    • Smyth MJ, Godfrey DI. NKT cells and tumor immunity-a double-edged sword. Nat Immunol 2000; 1:459-460.
    • (2000) Nat Immunol , vol.1 , pp. 459-460
    • Smyth, M.J.1    Godfrey, D.I.2
  • 21
    • 0242575287 scopus 로고    scopus 로고
    • Natural killer T cells: Natural or unnatural regulators of autoimmunity?
    • Hammond KJ, Kronenberg M. Natural killer T cells: natural or unnatural regulators of autoimmunity? Curr Opin Immunol 2003; 15:683-689.
    • (2003) Curr Opin Immunol , vol.15 , pp. 683-689
    • Hammond, K.J.1    Kronenberg, M.2
  • 22
    • 0037364854 scopus 로고    scopus 로고
    • Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity
    • Wilson SB, Delovitch TL. Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nat Rev Immunol 2003; 3:211-222.
    • (2003) Nat Rev Immunol , vol.3 , pp. 211-222
    • Wilson, S.B.1    Delovitch, T.L.2
  • 23
    • 5444242663 scopus 로고    scopus 로고
    • Therapeutic manipulation of iNKT cells in autoimmunity: Modes of action and potential risks
    • Mars LT, Novak J, Liblau RS, Lehuen A. Therapeutic manipulation of iNKT cells in autoimmunity: modes of action and potential risks. Trends Immunol 2004; 25:471-476.
    • (2004) Trends Immunol , vol.25 , pp. 471-476
    • Mars, L.T.1    Novak, J.2    Liblau, R.S.3    Lehuen, A.4
  • 24
    • 24644513738 scopus 로고    scopus 로고
    • The role of natural killer T cells in atherosclerosis
    • In press
    • Major AS, Van Kaer L. The role of natural killer T cells in atherosclerosis. Curr Immunol Rev 2005; In press.
    • (2005) Curr Immunol Rev
    • Major, A.S.1    Van Kaer, L.2
  • 27
    • 0347911963 scopus 로고    scopus 로고
    • Cutaneous immunization rapidly activates liver invariant Vα14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact hypersensitivity
    • Campos RA, Szczepanik M, Itakura A, Akahira-Azuma M, Sidobre S, Kronenberg M, Askenase PW. Cutaneous immunization rapidly activates liver invariant Vα14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact hypersensitivity. J Exp Med 2003; 198:1785-1796.
    • (2003) J Exp Med , vol.198 , pp. 1785-1796
    • Campos, R.A.1    Szczepanik, M.2    Itakura, A.3    Akahira-Azuma, M.4    Sidobre, S.5    Kronenberg, M.6    Askenase, P.W.7
  • 28
    • 0036850908 scopus 로고    scopus 로고
    • Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
    • Heller F, Fuss IJ, Nieuwenhuis EE, Blumberg RS, Strober W. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 2002; 17:629-638.
    • (2002) Immunity , vol.17 , pp. 629-638
    • Heller, F.1    Fuss, I.J.2    Nieuwenhuis, E.E.3    Blumberg, R.S.4    Strober, W.5
  • 31
    • 13544262688 scopus 로고    scopus 로고
    • Direct regulatory role of NKT cells in allogeneic graft survival is dependent on the quantitative strength of antigenicity
    • Oh K, Kim S, Park SH, Gu H, Roopenian D, Chung DH, Kim YS, Lee DS. Direct regulatory role of NKT cells in allogeneic graft survival is dependent on the quantitative strength of antigenicity. J Immunol 2005; 174:2030-2036.
    • (2005) J Immunol , vol.174 , pp. 2030-2036
    • Oh, K.1    Kim, S.2    Park, S.H.3    Gu, H.4    Roopenian, D.5    Chung, D.H.6    Kim, Y.S.7    Lee, D.S.8
  • 32
    • 0037083355 scopus 로고    scopus 로고
    • Long-term survival of corneal allografts is dependent on intact CD1d-reactive NKT cells
    • Sonoda KH, Taniguchi M, Stein-Streilein J. Long-term survival of corneal allografts is dependent on intact CD1d-reactive NKT cells. J Immunol 2002; 168:2028-2034.
    • (2002) J Immunol , vol.168 , pp. 2028-2034
    • Sonoda, K.H.1    Taniguchi, M.2    Stein-Streilein, J.3
  • 33
  • 34
    • 0033230839 scopus 로고    scopus 로고
    • CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site
    • Sonoda KH, Exley M, Snapper S, Balk SP, Stein-Streilein J. CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site. J Exp Med 1999; 190:1215-1226.
    • (1999) J Exp Med , vol.190 , pp. 1215-1226
    • Sonoda, K.H.1    Exley, M.2    Snapper, S.3    Balk, S.P.4    Stein-Streilein, J.5
  • 35
    • 0033231490 scopus 로고    scopus 로고
    • Immune privilege: Keeping an eye on natural killer T cells
    • Hong S, Van Kaer L. Immune privilege: keeping an eye on natural killer T cells. J Exp Med 1999; 190:1197-1200.
    • (1999) J Exp Med , vol.190 , pp. 1197-1200
    • Hong, S.1    Van Kaer, L.2
  • 37
    • 0034569294 scopus 로고    scopus 로고
    • Immune suppression and skin cancer development: Regulation by NKT cells
    • Moodycliffe AM, Nghiem D, Clydesdale G, Ullrich SE. Immune suppression and skin cancer development: regulation by NKT cells. Nat Immunol 2000; 1:521-525.
    • (2000) Nat Immunol , vol.1 , pp. 521-525
    • Moodycliffe, A.M.1    Nghiem, D.2    Clydesdale, G.3    Ullrich, S.E.4
  • 40
    • 3142680192 scopus 로고    scopus 로고
    • + invariant NKT cells for the infectious spread of tolerance and the induction of specific regulatory T cells
    • + invariant NKT cells for the infectious spread of tolerance and the induction of specific regulatory T cells. J Immunol 2004; 173:1043-1050.
    • (2004) J Immunol , vol.173 , pp. 1043-1050
    • Roelofs-Haarhuis, K.1    Wu, X.2    Gleichmann, E.3
  • 41
    • 0032971371 scopus 로고    scopus 로고
    • The CD1 system: Antigen-presenting molecules for T cell recognition of lipids and glycolipids
    • Porcelli SA, Modlin RL. The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu Rev Immunol 1999; 17:297-329.
    • (1999) Annu Rev Immunol , vol.17 , pp. 297-329
    • Porcelli, S.A.1    Modlin, R.L.2
  • 42
    • 0037290833 scopus 로고    scopus 로고
    • CD1-restricted antigen presentation: An oily matter
    • Joyce S, Van Kaer L. CD1-restricted antigen presentation: an oily matter. Curr Opin Immunol 2003; 15:95-104.
    • (2003) Curr Opin Immunol , vol.15 , pp. 95-104
    • Joyce, S.1    Van Kaer, L.2
  • 43
    • 0030826423 scopus 로고    scopus 로고
    • Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove
    • Zeng Z, Castano AR, Segelke BW, Stura EA, Peterson PA, Wilson IA. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 1997; 277:339-345.
    • (1997) Science , vol.277 , pp. 339-345
    • Zeng, Z.1    Castano, A.R.2    Segelke, B.W.3    Stura, E.A.4    Peterson, P.A.5    Wilson, I.A.6
  • 47
    • 0032055191 scopus 로고    scopus 로고
    • Tissue-specific recognition of mouse CD1 molecules
    • Park SH, Roark JH, Bendelac A. Tissue-specific recognition of mouse CD1 molecules. J Immunol 1998; 160:3128-3134.
    • (1998) J Immunol , vol.160 , pp. 3128-3134
    • Park, S.H.1    Roark, J.H.2    Bendelac, A.3
  • 49
    • 0027177356 scopus 로고
    • Agelasphins, novel α-galactosylceramides from the marine sponge Agelas mauritianus
    • Natori T, Koezuka Y, Higa T. Agelasphins, novel α- galactosylceramides from the marine sponge Agelas mauritianus. Tetrahedron Lett 1993; 34:5591-5592.
    • (1993) Tetrahedron Lett , vol.34 , pp. 5591-5592
    • Natori, T.1    Koezuka, Y.2    Higa, T.3
  • 51
    • 0032547849 scopus 로고    scopus 로고
    • CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
    • Brossay L, Chioda M, Burdin N, Koezuka Y, Casorati G, Dellabona P, Kronenberg M. CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 1998; 188:1521-1528.
    • (1998) J Exp Med , vol.188 , pp. 1521-1528
    • Brossay, L.1    Chioda, M.2    Burdin, N.3    Koezuka, Y.4    Casorati, G.5    Dellabona, P.6    Kronenberg, M.7
  • 52
    • 0032547823 scopus 로고    scopus 로고
    • CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
    • Spada FM, Koezuka Y, Porcelli SA. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J Exp Med 1998; 188:1529-1534.
    • (1998) J Exp Med , vol.188 , pp. 1529-1534
    • Spada, F.M.1    Koezuka, Y.2    Porcelli, S.A.3
  • 53
    • 0037744604 scopus 로고    scopus 로고
    • Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells
    • Motsinger A, Azimzadeh A, Stanic AK, Johnson RP, Van Kaer L, Joyce S, Unutmaz D. Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells. J Virol 2003; 77:8153-8158.
    • (2003) J Virol , vol.77 , pp. 8153-8158
    • Motsinger, A.1    Azimzadeh, A.2    Stanic, A.K.3    Johnson, R.P.4    Van Kaer, L.5    Joyce, S.6    Unutmaz, D.7
  • 55
    • 12844285609 scopus 로고    scopus 로고
    • Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion
    • Schmieg J, Yang G, Franck RW, Van Rooijen N, Tsuji M. Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion. Proc Natl Acad Sci U S A 2005; 102:1127-1132.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1127-1132
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    Van Rooijen, N.4    Tsuji, M.5
  • 56
    • 0035887526 scopus 로고    scopus 로고
    • Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: Critical role for B7 in CD1d-dependent NKT cell interferon gamma production
    • Ikarashi Y, Mikami R, Bendelac A, Terme M, Chaput N, Terada M, Tursz T, Angevin E, Lemonnier FA, Wakasugi H, Zitvogel L. Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production. J Exp Med 2001; 194:1179-1186.
    • (2001) J Exp Med , vol.194 , pp. 1179-1186
    • Ikarashi, Y.1    Mikami, R.2    Bendelac, A.3    Terme, M.4    Chaput, N.5    Terada, M.6    Tursz, T.7    Angevin, E.8    Lemonnier, F.A.9    Wakasugi, H.10    Zitvogel, L.11
  • 57
    • 3042545974 scopus 로고    scopus 로고
    • The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation
    • Fujii S, Liu K, Smith C, Bonito AJ, Steinman RM. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J Exp Med 2004; 199:1607-1618.
    • (2004) J Exp Med , vol.199 , pp. 1607-1618
    • Fujii, S.1    Liu, K.2    Smith, C.3    Bonito, A.J.4    Steinman, R.M.5
  • 58
    • 0033526066 scopus 로고    scopus 로고
    • The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells
    • Kitamura H, Iwakabe K, Yahata T, Nishimura S, Ohta A, Ohmi Y, Sato M, Takeda K, Okumura K, Van Kaer L, Kawano T, Taniguchi M, Nishimura T. The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J Exp Med 1999; 189:1121-1128.
    • (1999) J Exp Med , vol.189 , pp. 1121-1128
    • Kitamura, H.1    Iwakabe, K.2    Yahata, T.3    Nishimura, S.4    Ohta, A.5    Ohmi, Y.6    Sato, M.7    Takeda, K.8    Okumura, K.9    Van Kaer, L.10    Kawano, T.11    Taniguchi, M.12    Nishimura, T.13
  • 61
    • 0032728606 scopus 로고    scopus 로고
    • Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules
    • Naidenko OV, Maher JK, Ernst WA, Sakai T, Modlin RL, Kronenberg M. Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules. J Exp Med 1999; 190:1069-1080.
    • (1999) J Exp Med , vol.190 , pp. 1069-1080
    • Naidenko, O.V.1    Maher, J.K.2    Ernst, W.A.3    Sakai, T.4    Modlin, R.L.5    Kronenberg, M.6
  • 62
    • 0032533447 scopus 로고    scopus 로고
    • Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells
    • Brossay L, Naidenko O, Burdin N, Matsuda J, Sakai T, Kronenberg M. Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells. J Immunol 1998; 161:5124-5128.
    • (1998) J Immunol , vol.161 , pp. 5124-5128
    • Brossay, L.1    Naidenko, O.2    Burdin, N.3    Matsuda, J.4    Sakai, T.5    Kronenberg, M.6
  • 64
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K, Miyake S, Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001; 413:531-534.
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 67
    • 2942739333 scopus 로고    scopus 로고
    • The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells
    • Oki S, Chiba A, Yamamura T, Miyake S. The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells. J Clin Invest 2004; 113:1631-1640.
    • (2004) J Clin Invest , vol.113 , pp. 1631-1640
    • Oki, S.1    Chiba, A.2    Yamamura, T.3    Miyake, S.4
  • 69
    • 0345167831 scopus 로고    scopus 로고
    • Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand α- galactosylceramide
    • Schmieg J, Yang G, Franck RW, Tsuji M. Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand α-galactosylceramide. J Exp Med 2003; 198:1631-1641.
    • (2003) J Exp Med , vol.198 , pp. 1631-1641
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    Tsuji, M.4
  • 71
    • 0242500336 scopus 로고    scopus 로고
    • The paradox of immune molecular recognition of p α- galactosylceramide: Low affinity, low specificity for CD1d, high affinity for αβ TCRs
    • Cantu C, Benlagha K, Savage PB, Bendelac A, Teyton L. The paradox of immune molecular recognition of p α-galactosylceramide: low affinity, low specificity for CD1d, high affinity for αβ TCRs. J Immunol 2003; 170:4673-4682.
    • (2003) J Immunol , vol.170 , pp. 4673-4682
    • Cantu, C.1    Benlagha, K.2    Savage, P.B.3    Bendelac, A.4    Teyton, L.5
  • 73
    • 1642454720 scopus 로고    scopus 로고
    • Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides
    • Ortaldo JR, Young HA, Winkler-Pickett RT, Bere EWJ, Murphy WJ, Wiltrout RH. Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides. J Immunol 2004; 172:943-953.
    • (2004) J Immunol , vol.172 , pp. 943-953
    • Ortaldo, J.R.1    Young, H.A.2    Winkler-Pickett, R.T.3    Bere, E.W.J.4    Murphy, W.J.5    Wiltrout, R.H.6
  • 78
    • 0034657955 scopus 로고    scopus 로고
    • Cutting edge: The IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: Exploring the role of GPIs in NK T cell activation and antimalarial responses
    • Molano A, Park SH, Chiu YH, Nosseir S, Bendelac A, Tsuji M. Cutting edge: the IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: exploring the role of GPIs in NK T cell activation and antimalarial responses. J Immunol 2000; 164:5005-5009.
    • (2000) J Immunol , vol.164 , pp. 5005-5009
    • Molano, A.1    Park, S.H.2    Chiu, Y.H.3    Nosseir, S.4    Bendelac, A.5    Tsuji, M.6
  • 79
    • 0036785644 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d/NKT cell pathway
    • Procopio DC, Almeida IC, Torrecilhas AC, Cardoso JE, Teyton L, Travassos LR, Bendelac A, Gazzinelli RT. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d/NKT cell pathway. J Immunol 2002; 169:3926-3933.
    • (2002) J Immunol , vol.169 , pp. 3926-3933
    • Procopio, D.C.1    Almeida, I.C.2    Torrecilhas, A.C.3    Cardoso, J.E.4    Teyton, L.5    Travassos, L.R.6    Bendelac, A.7    Gazzinelli, R.T.8
  • 80
    • 0038152830 scopus 로고    scopus 로고
    • Cross-presentation of disialoganglioside GD3 to natural killer T cells
    • Wu DY, Segal NH, Sidobre S, Kronenberg M, Chapman PB. Cross-presentation of disialoganglioside GD3 to natural killer T cells. J Exp Med 2003; 198:173-181.
    • (2003) J Exp Med , vol.198 , pp. 173-181
    • Wu, D.Y.1    Segal, N.H.2    Sidobre, S.3    Kronenberg, M.4    Chapman, P.B.5
  • 84
    • 20144366715 scopus 로고    scopus 로고
    • Innate immunity: NKT cells in the spotlight
    • In press
    • Van Kaer L, Joyce S. Innate immunity: NKT cells in the spotlight. Curr Biol 2005; In press.
    • (2005) Curr Biol
    • Van Kaer, L.1    Joyce, S.2
  • 85
    • 0347776209 scopus 로고    scopus 로고
    • Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
    • Brigl M, Bry L, Kent SC, Gumperz JE, Brenner MB. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat Immunol 2003; 4:1230-1237.
    • (2003) Nat Immunol , vol.4 , pp. 1230-1237
    • Brigl, M.1    Bry, L.2    Kent, S.C.3    Gumperz, J.E.4    Brenner, M.B.5
  • 86
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 91
    • 0038461995 scopus 로고    scopus 로고
    • Drugs from the deep: Marine natural products as drug candidates
    • Haefher B. Drugs from the deep: marine natural products as drug candidates. Drug Discov Today 2003; 8:536-544.
    • (2003) Drug Discov Today , vol.8 , pp. 536-544
    • Haefher, B.1
  • 93
    • 11244304412 scopus 로고    scopus 로고
    • α-galactosylceramide therapy for autoimmune diseases: Prospects and obstacles
    • Van Kaer L. α-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles. Nat Rev Immunol 2005; 5:31-42.
    • (2005) Nat Rev Immunol , vol.5 , pp. 31-42
    • Van Kaer, L.1
  • 94
    • 0037018101 scopus 로고    scopus 로고
    • Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining
    • Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 2002; 195:625-636.
    • (2002) J Exp Med , vol.195 , pp. 625-636
    • Gumperz, J.E.1    Miyake, S.2    Yamamura, T.3    Brenner, M.B.4
  • 95
    • 0037018108 scopus 로고    scopus 로고
    • Distinct functional lineages of human Vα24 natural killer T cells
    • Lee PT, Benlagha K, Teyton L, Bendelac A. Distinct functional lineages of human Vα24 natural killer T cells. J Exp Med 2002; 195:637-641.
    • (2002) J Exp Med , vol.195 , pp. 637-641
    • Lee, P.T.1    Benlagha, K.2    Teyton, L.3    Bendelac, A.4
  • 96
    • 0032169234 scopus 로고    scopus 로고
    • Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12-treated mice: A major role for bone marrow in NKT cell homeostasis
    • Eberl G, MacDonald HR. Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis. Immunity 1998; 9:345-353.
    • (1998) Immunity , vol.9 , pp. 345-353
    • Eberl, G.1    MacDonald, H.R.2
  • 97
    • 0034002676 scopus 로고    scopus 로고
    • Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells
    • Eberl G, MacDonald HR. Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells. Eur J Immunol 2000; 30:985-992.
    • (2000) Eur J Immunol , vol.30 , pp. 985-992
    • Eberl, G.1    MacDonald, H.R.2
  • 102
    • 12744268685 scopus 로고    scopus 로고
    • NKT cells are relatively resistant to apoptosis
    • Seino K, Harada M, Taniguchi M. NKT cells are relatively resistant to apoptosis. Trends Immunol 2004; 25:219-221.
    • (2004) Trends Immunol , vol.25 , pp. 219-221
    • Seino, K.1    Harada, M.2    Taniguchi, M.3
  • 105
    • 0037307796 scopus 로고    scopus 로고
    • The contribution of NKT cells, NK cells, and other γ-chain- dependent non-T non-B cells to IL-12-mediated rejection of tumors
    • Park SH, Kyin T, Bendelac A, Carnaud C. The contribution of NKT cells, NK cells, and other γ-chain-dependent non-T non-B cells to IL-12-mediated rejection of tumors. J Immunol 2003; 170:1197-1201.
    • (2003) J Immunol , vol.170 , pp. 1197-1201
    • Park, S.H.1    Kyin, T.2    Bendelac, A.3    Carnaud, C.4
  • 106
    • 0037350581 scopus 로고    scopus 로고
    • Dominant effector memory characteristics, capacity for dynamic adaptive expansion, and sex bias in the innate Vα24 NKT cell compartment
    • Sandberg JK, Bhardwaj N, Nixon DF. Dominant effector memory characteristics, capacity for dynamic adaptive expansion, and sex bias in the innate Vα24 NKT cell compartment. Eur J Immunol 2003; 33:588-596.
    • (2003) Eur J Immunol , vol.33 , pp. 588-596
    • Sandberg, J.K.1    Bhardwaj, N.2    Nixon, D.F.3
  • 107
    • 0033198183 scopus 로고    scopus 로고
    • Cutting edge: Activation of NK T cells by CD1d and α- galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype
    • Singh N, Hong S, Scherer DC, Serizawa I, Burdin N, Kronenberg M, Koezuka Y, Van Kaer L. Cutting edge: activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J Immunol 1999; 163:2373-2377.
    • (1999) J Immunol , vol.163 , pp. 2373-2377
    • Singh, N.1    Hong, S.2    Scherer, D.C.3    Serizawa, I.4    Burdin, N.5    Kronenberg, M.6    Koezuka, Y.7    Van Kaer, L.8
  • 110
    • 0036735859 scopus 로고    scopus 로고
    • Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide-loaded DCs
    • Fujii S, Shimizu K, Kronenberg M, Steinman RM. Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide- loaded DCs. Nat Immunol 2002; 3:867-874.
    • (2002) Nat Immunol , vol.3 , pp. 867-874
    • Fujii, S.1    Shimizu, K.2    Kronenberg, M.3    Steinman, R.M.4
  • 113
    • 0028970661 scopus 로고
    • TAP-independent, β2-microglobulin-dependent surface expression of functional mouse CD1.1
    • Brutkiewicz RR, Bennink JR, Yewdell JW, Bendelac A. TAP-independent, β2-microglobulin-dependent surface expression of functional mouse CD1.1. J Exp Med 1995; 182:1913-1919.
    • (1995) J Exp Med , vol.182 , pp. 1913-1919
    • Brutkiewicz, R.R.1    Bennink, J.R.2    Yewdell, J.W.3    Bendelac, A.4
  • 114
    • 2942683192 scopus 로고    scopus 로고
    • Antigen-induced tolerance by intrathymic modulation of self-recognizing inhibitory receptors
    • Hayakawa Y, Berzins SP, Crowe NY, Godfrey DI, Smyth MJ. Antigen-induced tolerance by intrathymic modulation of self-recognizing inhibitory receptors. Nat Immunol 2004; 5:590-596.
    • (2004) Nat Immunol , vol.5 , pp. 590-596
    • Hayakawa, Y.1    Berzins, S.P.2    Crowe, N.Y.3    Godfrey, D.I.4    Smyth, M.J.5
  • 115
    • 0141889082 scopus 로고    scopus 로고
    • Repeated α-galactosylceramide administration results in expansion of Vα14 NKT cells and alleviates inflammatory dermatitis in MKL-lpr/lpr mice
    • Yang J-Q, Saxena V, Xu H, Van Kaer L, Wang CR, Singh RR. Repeated α-galactosylceramide administration results in expansion of Vα14 NKT cells and alleviates inflammatory dermatitis in MKL-lpr/lpr mice. J Immunol 2003; 171:4439-4446.
    • (2003) J Immunol , vol.171 , pp. 4439-4446
    • Yang, J.-Q.1    Saxena, V.2    Xu, H.3    Van Kaer, L.4    Wang, C.R.5    Singh, R.R.6
  • 116
    • 0032729476 scopus 로고    scopus 로고
    • Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells
    • Carnaud C, Lee D, Donnars O, Park SH, Beavis A, Koezuka Y, Bendelac A. Cutting edge: cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J Immunol 1999; 163:4647-4650.
    • (1999) J Immunol , vol.163 , pp. 4647-4650
    • Carnaud, C.1    Lee, D.2    Donnars, O.3    Park, S.H.4    Beavis, A.5    Koezuka, Y.6    Bendelac, A.7
  • 117
  • 118
    • 15444371866 scopus 로고    scopus 로고
    • Cutting edge: IFN-γ signaling to macrophages is required for optimal Vα14i NK T/NK cell cross-talk
    • Wesley JD, Robbins SH, Sidobre S, Kronenberg M, Terrizzi S, Brossay L. Cutting edge: IFN-γ signaling to macrophages is required for optimal Vα14i NK T/NK cell cross-talk. J Immunol 2005; 174:3864-3868.
    • (2005) J Immunol , vol.174 , pp. 3864-3868
    • Wesley, J.D.1    Robbins, S.H.2    Sidobre, S.3    Kronenberg, M.4    Terrizzi, S.5    Brossay, L.6
  • 119
    • 0037787982 scopus 로고    scopus 로고
    • Activation of natural killer T cells by α-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
    • Fujii S, Shimizu K, Smith C, Bonifaz L, Steinman RM. Activation of natural killer T cells by α-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J Exp Med 2003; 198:267-279.
    • (2003) J Exp Med , vol.198 , pp. 267-279
    • Fujii, S.1    Shimizu, K.2    Smith, C.3    Bonifaz, L.4    Steinman, R.M.5
  • 123
  • 124
    • 0033022704 scopus 로고    scopus 로고
    • Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis
    • Burdin N, Brossay L, Kronenberg M. Immunization with α- galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis. Eur J Immunol 1999; 29:2014-2025.
    • (1999) Eur J Immunol , vol.29 , pp. 2014-2025
    • Burdin, N.1    Brossay, L.2    Kronenberg, M.3
  • 125
    • 3242743546 scopus 로고    scopus 로고
    • Schistosoma mansoni and α-galactosylceramide: Prophylactic effect of Th1 immune suppression in a mouse model of Graves' hyperthyroidism
    • Nagayama Y, Watanabe K, Niwa M, McLachlan SM, Rapoport B. Schistosoma mansoni and α-galactosylceramide: prophylactic effect of Th1 immune suppression in a mouse model of Graves' hyperthyroidism. J Immunol 2004; 173:2167-2173.
    • (2004) J Immunol , vol.173 , pp. 2167-2173
    • Nagayama, Y.1    Watanabe, K.2    Niwa, M.3    McLachlan, S.M.4    Rapoport, B.5
  • 126
  • 129
    • 0031897207 scopus 로고    scopus 로고
    • IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells
    • Leite-De-Moraes MC, Moreau G, Arnould A, Machavoine F, Garcia C, Papiernik M, Dy M. IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells. Eur J Immunol 1998; 28:1507-1515.
    • (1998) Eur J Immunol , vol.28 , pp. 1507-1515
    • Leite-De-Moraes, M.C.1    Moreau, G.2    Arnould, A.3    Machavoine, F.4    Garcia, C.5    Papiernik, M.6    Dy, M.7
  • 132
    • 0035159618 scopus 로고    scopus 로고
    • Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of Vα14 NK T cells
    • Pal E, Tabira T, Kawano T, Taniguchi M, Miyake S, Yamamura T. Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of Vα14 NK T cells. J Immunol 2001; 166:662-668.
    • (2001) J Immunol , vol.166 , pp. 662-668
    • Pal, E.1    Tabira, T.2    Kawano, T.3    Taniguchi, M.4    Miyake, S.5    Yamamura, T.6
  • 133
    • 0035873434 scopus 로고    scopus 로고
    • Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways
    • Hayakawa Y, Takeda K, Yagita H, Van Kaer L, Saiki I, Okumura K. Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways. J Immunol 2001; 166:6012-6018.
    • (2001) J Immunol , vol.166 , pp. 6012-6018
    • Hayakawa, Y.1    Takeda, K.2    Yagita, H.3    Van Kaer, L.4    Saiki, I.5    Okumura, K.6
  • 134
    • 0029904115 scopus 로고    scopus 로고
    • + T cells upon NKR-P1 cross-linking
    • + T cells upon NKR-P1 cross-linking. J Exp Med 1996; 183:2391-2396.
    • (1996) J Exp Med , vol.183 , pp. 2391-2396
    • Arase, H.1    Arase, N.2    Saito, T.3
  • 136
    • 0036256943 scopus 로고    scopus 로고
    • Immunotherapy with ligands of natural killer T cells
    • Wilson MT, Singh AK, Van Kaer L. Immunotherapy with ligands of natural killer T cells. Trends Mol Med 2002; 8:225-231.
    • (2002) Trends Mol Med , vol.8 , pp. 225-231
    • Wilson, M.T.1    Singh, A.K.2    Van Kaer, L.3
  • 137
    • 1542749378 scopus 로고    scopus 로고
    • α-galactosylceramide: Potential immunomodulatory activity and future application
    • Hayakawa Y, Godfrey DI, Smyth MJ. α-Galactosylceramide: potential immunomodulatory activity and future application. Curr Med Chem 2004; 11:241-252.
    • (2004) Curr Med Chem , vol.11 , pp. 241-252
    • Hayakawa, Y.1    Godfrey, D.I.2    Smyth, M.J.3
  • 138
    • 0041422186 scopus 로고    scopus 로고
    • α-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis
    • Hayakawa Y, Rovero S, Forni G, Smyth MJ. α-Galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis. Proc Natl Acad Sci U S A 2003; 100:9464-9469.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9464-9469
    • Hayakawa, Y.1    Rovero, S.2    Forni, G.3    Smyth, M.J.4
  • 142
    • 0034970326 scopus 로고    scopus 로고
    • Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide
    • Hayakawa Y, Takeda K, Yagita H, Kakuta S, Iwakura Y, Van Kaer L, Saiki I, Okumura K. Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide. Eur J Immunol 2001; 31:1720-1727.
    • (2001) Eur J Immunol , vol.31 , pp. 1720-1727
    • Hayakawa, Y.1    Takeda, K.2    Yagita, H.3    Kakuta, S.4    Iwakura, Y.5    Van Kaer, L.6    Saiki, I.7    Okumura, K.8
  • 143
    • 0033197917 scopus 로고    scopus 로고
    • Cutting edge: Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide
    • Toura I, Kawano T, Akutsu Y, Nakayama T, Ochiai T, Taniguchi M. Cutting edge: inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide. J Immunol 1999; 163:2387-2391.
    • (1999) J Immunol , vol.163 , pp. 2387-2391
    • Toura, I.1    Kawano, T.2    Akutsu, Y.3    Nakayama, T.4    Ochiai, T.5    Taniguchi, M.6
  • 144
    • 0036720437 scopus 로고    scopus 로고
    • IFN-γ-mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, α-galactosylceramide
    • Hayakawa Y, Takeda K, Yagita H, Smyth MJ, Van Kaer L, Okumura K, Saiki I. IFN-γ-mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, α-galactosylceramide. Blood 2002; 100:1728-1733.
    • (2002) Blood , vol.100 , pp. 1728-1733
    • Hayakawa, Y.1    Takeda, K.2    Yagita, H.3    Smyth, M.J.4    Van Kaer, L.5    Okumura, K.6    Saiki, I.7
  • 148
    • 0036839648 scopus 로고    scopus 로고
    • Activation of NKT cells protects mice from tuberculosis
    • Chackerian A, Alt J, Perera V, Behar SM. Activation of NKT cells protects mice from tuberculosis. Infect Immun 2002; 70:6302-6309.
    • (2002) Infect Immun , vol.70 , pp. 6302-6309
    • Chackerian, A.1    Alt, J.2    Perera, V.3    Behar, S.M.4
  • 151
    • 0037303639 scopus 로고    scopus 로고
    • Activation of natural killer (NK) T cells during murine cytomegalovirus infection enhances the antiviral response mediated by NK cells
    • Van Dommelen SL, Tabarias HA, Smyth MJ, Degli-Eposti MA. Activation of natural killer (NK) T cells during murine cytomegalovirus infection enhances the antiviral response mediated by NK cells. J Virol 2003; 77:1877-1884.
    • (2003) J Virol , vol.77 , pp. 1877-1884
    • Van Dommelen, S.L.1    Tabarias, H.A.2    Smyth, M.J.3    Degli-Eposti, M.A.4
  • 152
    • 0036223536 scopus 로고    scopus 로고
    • + T cells and amplification of antiviral immune responses to respiratory syncytial virus
    • + T cells and amplification of antiviral immune responses to respiratory syncytial virus. J Virol 2002; 76:4294-4303.
    • (2002) J Virol , vol.76 , pp. 4294-4303
    • Johnson, T.R.1    Hong, S.2    Van Kaer, L.3    Koezuka, Y.4    Graham, B.S.5
  • 154
    • 0034596944 scopus 로고    scopus 로고
    • Natural killer T cell activation inhibits hepatitis B virus replication in vivo
    • Kakimi K, Guidotti LG, Koezuka Y, Chisari FV. Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J Exp Med 2000; 192:921-930.
    • (2000) J Exp Med , vol.192 , pp. 921-930
    • Kakimi, K.1    Guidotti, L.G.2    Koezuka, Y.3    Chisari, F.V.4
  • 155
    • 0035892741 scopus 로고    scopus 로고
    • Cutting edge: Inhibof hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver
    • Kakimi K, Lane TE, Chisari FV, Guidotti LG. Cutting edge: inhibof hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver. J Immunol 2001; 167:6701-6705.
    • (2001) J Immunol , vol.167 , pp. 6701-6705
    • Kakimi, K.1    Lane, T.E.2    Chisari, F.V.3    Guidotti, L.G.4
  • 158
    • 0036604214 scopus 로고    scopus 로고
    • Treatment with α-galactosylceramide before Trypanosoma cruzi infection provides protection or induces failure to thrive
    • Duthie MS, Kahn SJ. Treatment with α-galactosylceramide before Trypanosoma cruzi infection provides protection or induces failure to thrive. J Immunol 2002; 168:5778-5785.
    • (2002) J Immunol , vol.168 , pp. 5778-5785
    • Duthie, M.S.1    Kahn, S.J.2
  • 160
    • 0034746796 scopus 로고    scopus 로고
    • + natural killer T cells by α-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans
    • + natural killer T cells by α-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans. Infect Immun 2001; 69:213-220.
    • (2001) Infect Immun , vol.69 , pp. 213-220
    • Kawakami, K.1    Kinjo, Y.2    Yara, S.3    Koguchi, Y.4    Uezu, K.5    Nakayama, T.6    Taniguchi, M.7    Saito, A.8
  • 161
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • Delovitch TL, Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity 1997; 7:727-738.
    • (1997) Immunity , vol.7 , pp. 727-738
    • Delovitch, T.L.1    Singh, B.2
  • 162
    • 0035061536 scopus 로고    scopus 로고
    • Tolerance to islet autoantigens in type 1 diabetes
    • Bach JF, Chatenoud L. Tolerance to islet autoantigens in type 1 diabetes. Annu Rev Immunol 2001; 19:131-161.
    • (2001) Annu Rev Immunol , vol.19 , pp. 131-161
    • Bach, J.F.1    Chatenoud, L.2
  • 163
    • 0035817251 scopus 로고    scopus 로고
    • CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes
    • Wang B, Geng YB, Wang CR. CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes. J Exp Med 2001; 194:313-320.
    • (2001) J Exp Med , vol.194 , pp. 313-320
    • Wang, B.1    Geng, Y.B.2    Wang, C.R.3
  • 165
    • 2342650811 scopus 로고    scopus 로고
    • Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T cells
    • Mi Q-S, Ly D, Zucker P, McGarry M, Delovitch TL. Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T cells. Diabetes 2004; 53:1303-1310.
    • (2004) Diabetes , vol.53 , pp. 1303-1310
    • Mi, Q.-S.1    Ly, D.2    Zucker, P.3    McGarry, M.4    Delovitch, T.L.5
  • 166
    • 3042842679 scopus 로고    scopus 로고
    • CD1d-restricted T-cell subsets and dendritic cell function in autoimmunity
    • Bollyky PL, Wilson SB. CD1d-restricted T-cell subsets and dendritic cell function in autoimmunity. Immunol Cell Biol 2004; 82:307-314.
    • (2004) Immunol Cell Biol , vol.82 , pp. 307-314
    • Bollyky, P.L.1    Wilson, S.B.2
  • 168
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 1996; 85:299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 169
    • 0033231305 scopus 로고    scopus 로고
    • Assessment of animal models for MS and demyelinating disease in the design of rational therapy
    • Steinman L. Assessment of animal models for MS and demyelinating disease in the design of rational therapy. Neuron 1999; 24:511-514.
    • (1999) Neuron , vol.24 , pp. 511-514
    • Steinman, L.1
  • 170
    • 0035128996 scopus 로고    scopus 로고
    • Genetic models for CNS inflammation
    • Owens T, Wekerle H, Antel J. Genetic models for CNS inflammation. Nat Med 2001; 7:161-166.
    • (2001) Nat Med , vol.7 , pp. 161-166
    • Owens, T.1    Wekerle, H.2    Antel, J.3
  • 173
    • 0041968838 scopus 로고    scopus 로고
    • Activation of invariant NKT cells by α-GalCer administration protects mice from MOG35-55 induced EAE: Critical roles for administration route and IFN-γ
    • Furlan R, Bergami A, Cantarella D, Brambilla E, Taniguchi M, Dellabona P, Casorati G, Martino G. Activation of invariant NKT cells by α-GalCer administration protects mice from MOG35-55 induced EAE: critical roles for administration route and IFN-γ. Eur J Immunol 2003; 33:1830-1838.
    • (2003) Eur J Immunol , vol.33 , pp. 1830-1838
    • Furlan, R.1    Bergami, A.2    Cantarella, D.3    Brambilla, E.4    Taniguchi, M.5    Dellabona, P.6    Casorati, G.7    Martino, G.8
  • 175
    • 0042520880 scopus 로고    scopus 로고
    • Dissection of the genetic complexity of arthritis using animal models
    • Holmdahl R. Dissection of the genetic complexity of arthritis using animal models. J Autoimmun 2003; 21:99-103.
    • (2003) J Autoimmun , vol.21 , pp. 99-103
    • Holmdahl, R.1
  • 176
    • 0346458555 scopus 로고    scopus 로고
    • Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of α- galactosylceramide
    • Chiba A, Oki S, Miyamoto K, Hashimoto H, Yamamura T, Miyake S. Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of α-galactosylceramide. Arthritis Rheum 2004; 50:305-313.
    • (2004) Arthritis Rheum , vol.50 , pp. 305-313
    • Chiba, A.1    Oki, S.2    Miyamoto, K.3    Hashimoto, H.4    Yamamura, T.5    Miyake, S.6
  • 177
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Kotzin BL. Systemic lupus erythematosus. Cell 1996; 85:303-306.
    • (1996) Cell , vol.85 , pp. 303-306
    • Kotzin, B.L.1
  • 178
    • 0347988004 scopus 로고    scopus 로고
    • Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus
    • Zeng D, Liu Y, Sidobre S, Kronenberg M, Strober S. Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. J Clin Invest 2003; 112:1211-1222.
    • (2003) J Clin Invest , vol.112 , pp. 1211-1222
    • Zeng, D.1    Liu, Y.2    Sidobre, S.3    Kronenberg, M.4    Strober, S.5
  • 179
    • 0032247323 scopus 로고    scopus 로고
    • The thyrotropin (TSH)-releasing hormone receptor: Interaction with TSH and autoantibodies
    • Rapoport B, Chazenbalk GD, Jaume JC, McLachlan SM. The thyrotropin (TSH)-releasing hormone receptor: interaction with TSH and autoantibodies. Endocrine Rev 1998; 19:673-716.
    • (1998) Endocrine Rev , vol.19 , pp. 673-716
    • Rapoport, B.1    Chazenbalk, G.D.2    Jaume, J.C.3    McLachlan, S.M.4
  • 180
    • 0036218221 scopus 로고    scopus 로고
    • The immunology of mucosal models of inflammation
    • Strober W, Fuss IJ, Blumberg RS. The immunology of mucosal models of inflammation. Annu Rev Immunol 2002; 20:495-549.
    • (2002) Annu Rev Immunol , vol.20 , pp. 495-549
    • Strober, W.1    Fuss, I.J.2    Blumberg, R.S.3
  • 182
    • 13944264346 scopus 로고    scopus 로고
    • Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of Vα14 natural killer T cells in mice
    • Ueno Y, Tanaka S, Sumii M, Miyake S, Tazuma S, Taniguchi M, Yamamura T, Chayama K. Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of Vα14 natural killer T cells in mice. Inflamm Bowel Dis 2005; 11:35-41.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 35-41
    • Ueno, Y.1    Tanaka, S.2    Sumii, M.3    Miyake, S.4    Tazuma, S.5    Taniguchi, M.6    Yamamura, T.7    Chayama, K.8
  • 183
    • 2542498855 scopus 로고    scopus 로고
    • Autoimmune and inflammatory mechanisms in atherosclerosis
    • Wick G, Knoflach M, Xu Q. Autoimmune and inflammatory mechanisms in atherosclerosis. Annu Rev Immunol 2004; 22:361-403.
    • (2004) Annu Rev Immunol , vol.22 , pp. 361-403
    • Wick, G.1    Knoflach, M.2    Xu, Q.3
  • 184
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352:1685-1695.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 185
    • 0037157103 scopus 로고    scopus 로고
    • Implication of natural killer T cells in atherosclerosis development during a LPS-induced chronic inflammation
    • Ostos MA, Recalde D, Zakin MM, Scott-Algara D. Implication of natural killer T cells in atherosclerosis development during a LPS-induced chronic inflammation. FEBS Lett 2002; 519:23-29.
    • (2002) FEBS Lett , vol.519 , pp. 23-29
    • Ostos, M.A.1    Recalde, D.2    Zakin, M.M.3    Scott-Algara, D.4
  • 186
    • 0032887983 scopus 로고    scopus 로고
    • CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells
    • Melian A, Geng YJ, Sukhova GK, Libby P, Porcelli S. CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells. Am J Pathol 1999; 155:775-786.
    • (1999) Am J Pathol , vol.155 , pp. 775-786
    • Melian, A.1    Geng, Y.J.2    Sukhova, G.K.3    Libby, P.4    Porcelli, S.5
  • 190
    • 0034488558 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Molecular mechanisms and possible therapeutic strategies
    • van den Blink B, Jansen HM, Peppelenbosch MP. Idiopathic pulmonary fibrosis: molecular mechanisms and possible therapeutic strategies. Arch Immunol Ther Exp 2000; 48:539-545.
    • (2000) Arch Immunol Ther Exp , vol.48 , pp. 539-545
    • Van Den Blink, B.1    Jansen, H.M.2    Peppelenbosch, M.P.3
  • 192
    • 0000972921 scopus 로고
    • Elicitation of delayed allergic skin reactions with haptens: The dependence of elicitation on hapten combination with protein
    • Eisen HN, Orris L, Belman S. Elicitation of delayed allergic skin reactions with haptens: the dependence of elicitation on hapten combination with protein. J Exp Med 1952; 95:473-487.
    • (1952) J Exp Med , vol.95 , pp. 473-487
    • Eisen, H.N.1    Orris, L.2    Belman, S.3
  • 194
    • 2542486456 scopus 로고    scopus 로고
    • Asthma: Mechanisms of disease persistence and progression
    • Cohn L, Elias JA, Chupp GL. Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol 2004; 22:789-815.
    • (2004) Annu Rev Immunol , vol.22 , pp. 789-815
    • Cohn, L.1    Elias, J.A.2    Chupp, G.L.3
  • 195
    • 1642288509 scopus 로고    scopus 로고
    • Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL-4 and eotaxin production
    • Bilenki L, Yang J, Fan Y, Wang S, Yang X. Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL-4 and eotaxin production. Eur J Immunol 2004; 34:345-354.
    • (2004) Eur J Immunol , vol.34 , pp. 345-354
    • Bilenki, L.1    Yang, J.2    Fan, Y.3    Wang, S.4    Yang, X.5
  • 198
    • 4644327015 scopus 로고    scopus 로고
    • NKT cell ligand α-galactosylceramide blocks the induction of oral tolerance by triggering dendritic cell maturation
    • Chung Y, Chang WS, Kim S, Kang CY. NKT cell ligand α- galactosylceramide blocks the induction of oral tolerance by triggering dendritic cell maturation. Eur J Immunol 2004; 34:2471-2479.
    • (2004) Eur J Immunol , vol.34 , pp. 2471-2479
    • Chung, Y.1    Chang, W.S.2    Kim, S.3    Kang, C.Y.4
  • 199
    • 9644279528 scopus 로고    scopus 로고
    • Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model
    • Kim JO, Kim DH, Chang WS, Hong C, Park SH, Kim S, Kang CY. Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model. J Allergy Clin Immunol 2004; 114:1332-1338.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1332-1338
    • Kim, J.O.1    Kim, D.H.2    Chang, W.S.3    Hong, C.4    Park, S.H.5    Kim, S.6    Kang, C.Y.7
  • 200
    • 0035902174 scopus 로고    scopus 로고
    • Haematopoietic cell transplantation as immunotherapy
    • Appelbaum FR. Haematopoietic cell transplantation as immunotherapy. Nature 2001; 411:385-389.
    • (2001) Nature , vol.411 , pp. 385-389
    • Appelbaum, F.R.1
  • 202
    • 10844271455 scopus 로고    scopus 로고
    • Stimulation of host NKT cells by synthetic glycolipid regulates acute graft-versus-host disease by inducing Th2 polarization of donor T cells
    • Hashimoto D, Asakura S, Miyake S, Yamamura T, Van Kaer L, Liu C, Tanimoto M, Teshima T. Stimulation of host NKT cells by synthetic glycolipid regulates acute graft-versus-host disease by inducing Th2 polarization of donor T cells. J Immunol 2005; 174:551-556.
    • (2005) J Immunol , vol.174 , pp. 551-556
    • Hashimoto, D.1    Asakura, S.2    Miyake, S.3    Yamamura, T.4    Van Kaer, L.5    Liu, C.6    Tanimoto, M.7    Teshima, T.8
  • 203
    • 0033939943 scopus 로고    scopus 로고
    • Activation of hepatic NKT cells and subsequent liver injury following administration of a α-galactosylceramide
    • Osman Y, Kawamura T, Naito T, Takeda K, Van Kaer L, Okumura K, Abo T. Activation of hepatic NKT cells and subsequent liver injury following administration of a α-galactosylceramide. Eur J Immunol 2000; 30:1919-1928.
    • (2000) Eur J Immunol , vol.30 , pp. 1919-1928
    • Osman, Y.1    Kawamura, T.2    Naito, T.3    Takeda, K.4    Van Kaer, L.5    Okumura, K.6    Abo, T.7
  • 204
    • 0035336183 scopus 로고    scopus 로고
    • Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by α-galactosylceramide in mice
    • Nakagawa R, Nagafune I, Tazunoki Y, Ehara H, Tomura H, Iijima R, Motoki K, Kamishohara M, Seki S. Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by α-galactosylceramide in mice. J Immunol 2001; 166:6578-6584.
    • (2001) J Immunol , vol.166 , pp. 6578-6584
    • Nakagawa, R.1    Nagafune, I.2    Tazunoki, Y.3    Ehara, H.4    Tomura, H.5    Iijima, R.6    Motoki, K.7    Kamishohara, M.8    Seki, S.9
  • 207
    • 0036349224 scopus 로고    scopus 로고
    • Unique sensitivity to α-galactosylceramide of NKT cells in the uterus
    • Wang S, Li C, Kawamura H, Watanabe H, Abo T. Unique sensitivity to α-galactosylceramide of NKT cells in the uterus. Cell Immunol 2002; 215:98-105.
    • (2002) Cell Immunol , vol.215 , pp. 98-105
    • Wang, S.1    Li, C.2    Kawamura, H.3    Watanabe, H.4    Abo, T.5


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