메뉴 건너뛰기




Volumn 1, Issue 3, 2001, Pages 177-186

Autoreactivity by design: Innate B and T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 0035753991     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/35105052     Document Type: Review
Times cited : (363)

References (101)
  • 1
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov, R. & Janeway, C. A. Jr. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91, 295-298 (1997).
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 2
    • 0034531040 scopus 로고    scopus 로고
    • CD1d-restricted mouse Vα14 and human Vα24 T cells: Lymphocytes of innate immunity
    • Benlagha, K. & Bendelac, A. CD1d-restricted mouse Vα14 and human Vα24 T cells: lymphocytes of innate immunity. Semin. Immunol. 12, 537-542 (2000).
    • (2000) Semin. Immunol. , vol.12 , pp. 537-542
    • Benlagha, K.1    Bendelac, A.2
  • 3
    • 0033516689 scopus 로고    scopus 로고
    • Positive selection of natural autoreactive B cells
    • Hayakawa, K. et al. Positive selection of natural autoreactive B cells. Science 285, 113-116 (1999). The first demonstration that self-antigen drives the selection of innate lymphocytes.
    • (1999) Science , vol.285 , pp. 113-116
    • Hayakawa, K.1
  • 4
    • 0019427933 scopus 로고
    • Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae
    • Briles, D. E. et al. Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae. J. Exp. Med. 153, 694-705 (1981). The first demonstration that innate lymphocytes confer natural protection against infection.
    • (1981) J. Exp. Med. , vol.153 , pp. 694-705
    • Briles, D.E.1
  • 5
    • 0342939538 scopus 로고    scopus 로고
    • Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity
    • Shaw, P. X. et al. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J. Clin. Invest. 105, 1731-1740 (2000).
    • (2000) J. Clin. Invest. , vol.105 , pp. 1731-1740
    • Shaw, P.X.1
  • 6
    • 0033919320 scopus 로고    scopus 로고
    • B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a 'natural immune memory'
    • Martin, F. & Kearney, J. F. B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a 'natural immune memory'. Immunol. Rev. 175, 70-79 (2000).
    • (2000) Immunol. Rev. , vol.175 , pp. 70-79
    • Martin, F.1    Kearney, J.F.2
  • 7
    • 0029029565 scopus 로고
    • + T lymphocytes
    • + T lymphocytes. Science 268, 863-865 (1995).
    • (1995) Science , vol.268 , pp. 863-865
    • Bendelac, A.1
  • 8
    • 0031028170 scopus 로고    scopus 로고
    • Immunoglobulin e production in the absence of interleukin-4 secreting CD1-dependent cells
    • Smiley, S. T., Kaplan, M. H. & Grusby, M. J. Immunoglobulin E production in the absence of interleukin-4 secreting CD1-dependent cells. Science 275, 977-979 (1997).
    • (1997) Science , vol.275 , pp. 977-979
    • Smiley, S.T.1    Kaplan, M.H.2    Grusby, M.J.3
  • 9
    • 0035896733 scopus 로고    scopus 로고
    • The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families
    • Park, S. H. et al. The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families. J. Exp. Med. 193, 893-904 (2001). The intriguing demonstration that most of the mouse CD1d-restricted T-cell receptor repertoire is innate rather than adaptive.
    • (2001) J. Exp. Med. , vol.193 , pp. 893-904
    • Park, S.H.1
  • 10
    • 0033521624 scopus 로고    scopus 로고
    • Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments
    • Chiu, Y. H. et al. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J. Exp. Med. 189, 103-110 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 103-110
    • Chiu, Y.H.1
  • 11
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of vα14 NKT cells by glycosylceramides
    • Kawano, T. et al. CD1d-restricted and TCR-mediated activation of vα14 NKT cells by glycosylceramides. Science 278, 1626-1629 (1997).
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1
  • 12
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells
    • Groh, V., Steinle, A., Bauer, S. & Spies, T. Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells. Science 279, 1737-1740 (1998).
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 13
    • 0034689029 scopus 로고    scopus 로고
    • Self-recognition of CD1 by γ/δ T cells: Implications for innate immunity
    • Spada, F. M. et al. Self-recognition of CD1 by γ/δ T cells: implications for innate immunity. J. Exp. Med. 191, 937-948 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 937-948
    • Spada, F.M.1
  • 14
    • 0033621534 scopus 로고    scopus 로고
    • A population of murine γδ T cells that recognize an inducible MHC class Ib molecule
    • Crowley, M. P. et al. A population of murine γδ T cells that recognize an inducible MHC class Ib molecule. Science 287, 314-316 (2000).
    • (2000) Science , vol.287 , pp. 314-316
    • Crowley, M.P.1
  • 15
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer, S. et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285, 727-729 (1999).
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1
  • 16
    • 0023749983 scopus 로고
    • + (CD5) B cells that recognize phosphatidylcholine. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes
    • + (CD5) B cells that recognize phosphatidylcholine. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes. J. Exp. Med. 168, 687-698 (1988).
    • (1988) J. Exp. Med. , vol.168 , pp. 687-698
    • Mercolino, T.J.1    Arnold, L.W.2    Hawkins, L.A.3    Haughton, G.4
  • 17
    • 0024474720 scopus 로고
    • A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells. Definition of the VH11 family
    • Hardy, R. R., Carmack, C. E., Shinton, S. A., Riblet, R. J. & Hayakawa, K. A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells. Definition of the VH11 family. J. Immunol. 142, 3643-3651 (1989).
    • (1989) J. Immunol. , vol.142 , pp. 3643-3651
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Riblet, R.J.4    Hayakawa, K.5
  • 18
    • 0028176430 scopus 로고
    • Stimulation of human γδ T cells by nonpeptidic mycobacterial ligands
    • Constant, P. et al. Stimulation of human γδ T cells by nonpeptidic mycobacterial ligands. Science 264, 267-270 (1994).
    • (1994) Science , vol.264 , pp. 267-270
    • Constant, P.1
  • 19
    • 0029739371 scopus 로고    scopus 로고
    • Stimulation of γδ T cells by phosphoantigens
    • Fournie, J. J. & Bonneville, M. Stimulation of γδ T cells by phosphoantigens. Res. Immunol. 147, 338-347 (1996).
    • (1996) Res. Immunol. , vol.147 , pp. 338-347
    • Fournie, J.J.1    Bonneville, M.2
  • 21
    • 0029014868 scopus 로고
    • Early activation of human Vγ9Vδ2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands
    • Lang, F. et al. Early activation of human Vγ9Vδ2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands. J. Immunol. 154, 5986-5994 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 5986-5994
    • Lang, F.1
  • 22
    • 0028829424 scopus 로고
    • Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells
    • Morita, C. T. et al. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells. Immunity 3, 495-507 (1995).
    • (1995) Immunity , vol.3 , pp. 495-507
    • Morita, C.T.1
  • 23
    • 0033625350 scopus 로고    scopus 로고
    • A role for epithelial γδ T cells in tissue repair
    • Havran, W. L. A role for epithelial γδ T cells in tissue repair. Immunol. Res. 21, 63-69 (2000).
    • (2000) Immunol. Res. , vol.21 , pp. 63-69
    • Havran, W.L.1
  • 24
    • 0025836121 scopus 로고
    • Recognition of self antigens by skin-derived T cells with invariant γδ antigen receptors
    • Havran, W. L., Chien, Y. H. & Allison, J. P. Recognition of self antigens by skin-derived T cells with invariant γδ antigen receptors. Science 252, 1430-1432 (1991).
    • (1991) Science , vol.252 , pp. 1430-1432
    • Havran, W.L.1    Chien, Y.H.2    Allison, J.P.3
  • 25
    • 0031573625 scopus 로고    scopus 로고
    • Evidence that the same γδ T cells respond during infection-induced and autoimmune inflammation
    • Mukasa, A., Lahn, M., Pflum, E. K., Born, W. & O'Brien, R. L. Evidence that the same γδ T cells respond during infection-induced and autoimmune inflammation. J. Immunol. 159, 5787-5794 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 5787-5794
    • Mukasa, A.1    Lahn, M.2    Pflum, E.K.3    Born, W.4    O'Brien, R.L.5
  • 26
    • 0025730698 scopus 로고
    • The immunobiology of T cells with invariant γδ antigen receptors
    • Allison, J. P. & Havran, W. L. The immunobiology of T cells with invariant γδ antigen receptors. Annu. Rev. Immunol. 9, 679-705 (1991).
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 679-705
    • Allison, J.P.1    Havran, W.L.2
  • 27
    • 0032513352 scopus 로고    scopus 로고
    • Conservation of T cell receptor conformation in epidermal γδ cells with disrupted primary Vγ gene usage
    • Mallick-Wood, C. A. et al. Conservation of T cell receptor conformation in epidermal γδ cells with disrupted primary Vγ gene usage. Science 279, 1729-1733 (1998).
    • (1998) Science , vol.279 , pp. 1729-1733
    • Mallick-Wood, C.A.1
  • 28
    • 0034606295 scopus 로고    scopus 로고
    • Migration and differentiation of autoreactive B-1 cells induced by activated γ/δ T cells in antierythrocyte immunoglobulin transgenic mice
    • Watanabe, N. et al. Migration and differentiation of autoreactive B-1 cells induced by activated γ/δ T cells in antierythrocyte immunoglobulin transgenic mice. J. Exp. Med. 192, 1577-1586 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1577-1586
    • Watanabe, N.1
  • 30
    • 0034091286 scopus 로고    scopus 로고
    • γδ cells: A right time and a right place for a conserved third way of protection
    • Hayday, A. C. γδ cells: a right time and a right place for a conserved third way of protection. Annu. Rev. Immunol. 18, 975-1026 (2000). An up-to-date authoritative review on γδ T cells.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 975-1026
    • Hayday, A.C.1
  • 31
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by intraepithelial γδ T cells
    • Boismenu, R. & Havran, W. L. Modulation of epithelial cell growth by intraepithelial γδ T cells. Science 266, 1253-1255 (1994). A demonstration of the crosstalk between tissues and their resident lymphocytes.
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.L.2
  • 32
    • 0031052817 scopus 로고    scopus 로고
    • A novel subset of adult γδ thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire
    • Azuara, V., Levraud, J. P., Lembezat, M. P. & Pereira, P. A novel subset of adult γδ thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire. Eur. J. Immunol. 27, 544-553 (1997).
    • (1997) Eur. J. Immunol. , vol.27 , pp. 544-553
    • Azuara, V.1    Levraud, J.P.2    Lembezat, M.P.3    Pereira, P.4
  • 33
    • 0031049085 scopus 로고    scopus 로고
    • The natural killer gene complex: A genetic basis for understanding natural killer cell function and innate immunity
    • Brown, M. G., Scalzo, A. A., Matsumoto, K. & Yokoyama, W. M. The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity. Immunol. Rev. 155, 53-65 (1997).
    • (1997) Immunol. Rev. , vol.155 , pp. 53-65
    • Brown, M.G.1    Scalzo, A.A.2    Matsumoto, K.3    Yokoyama, W.M.4
  • 34
    • 0034252303 scopus 로고    scopus 로고
    • Ligands for the murine NKG2D receptor: Expression by tumor cells and activation of NK cells and macrophages
    • Diefenbach, A., Jamieson, A. M., Liu, S. D., Shastri, N. & Raulet, D. H. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nature Immunol. 1, 119-126 (2000).
    • (2000) Nature Immunol. , vol.1 , pp. 119-126
    • Diefenbach, A.1    Jamieson, A.M.2    Liu, S.D.3    Shastri, N.4    Raulet, D.H.5
  • 35
    • 0030702062 scopus 로고    scopus 로고
    • Control of self-reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors
    • Halary, F. et al. Control of self-reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors. Eur. J. Immunol. 27, 2812-2821 (1997). A demonstration that inhibitory receptors control autoreactive T-cell receptors.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2812-2821
    • Halary, F.1
  • 36
    • 0035887526 scopus 로고    scopus 로고
    • Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition. Critical role for b7 in CD1d-dependent NKT cell interferon γ production
    • Ikarashi, Y. et al. Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition. Critical role for b7 in CD1d-dependent NKT cell interferon γ production. J. Exp. Med. 194, 1179-1186 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1179-1186
    • Ikarashi, Y.1
  • 37
    • 0032494097 scopus 로고    scopus 로고
    • CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Vα24JαQ T cell receptor α chains
    • Exley, M., Porcelli, S., Furman, M., Garcia, J. & Balk, S. CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Vα24JαQ T cell receptor α chains. J. Exp. Med. 188, 867-876 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 867-876
    • Exley, M.1    Porcelli, S.2    Furman, M.3    Garcia, J.4    Balk, S.5
  • 38
    • 0028827376 scopus 로고
    • 2B4, a new member of the immunoglobulin gene superfamily, is expressed on murine dendritic epidermal T cells and plays a functional role in their killing of skin tumors
    • Schuhmachers, G. et al. 2B4, a new member of the immunoglobulin gene superfamily, is expressed on murine dendritic epidermal T cells and plays a functional role in their killing of skin tumors. J. Invest. Dermatol. 105, 592-596 (1995).
    • (1995) J. Invest. Dermatol. , vol.105 , pp. 592-596
    • Schuhmachers, G.1
  • 39
    • 0035914134 scopus 로고    scopus 로고
    • Regulation of cutaneous maligancy by γδ T cells
    • Girardi, M. et al. Regulation of cutaneous maligancy by γδ T cells. Science 294, 605-609 (2001).
    • (2001) Science , vol.294 , pp. 605-609
    • Girardi, M.1
  • 40
    • 0030474683 scopus 로고    scopus 로고
    • CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells
    • Bikah, G., Carey, J., Ciallella, J. R., Tarakhovsky, A. & Bondada, S. CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells. Science 274, 1906-1909 (1996).
    • (1996) Science , vol.274 , pp. 1906-1909
    • Bikah, G.1    Carey, J.2    Ciallella, J.R.3    Tarakhovsky, A.4    Bondada, S.5
  • 41
    • 0032846759 scopus 로고    scopus 로고
    • Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells
    • Sen, G., Bikah, G., Venkataraman, C. & Bondada, S. Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells. Eur. J. Immunol. 29, 3319-3328 (1999).
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3319-3328
    • Sen, G.1    Bikah, G.2    Venkataraman, C.3    Bondada, S.4
  • 42
    • 0027531439 scopus 로고
    • Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice
    • Reap, E. A., Sobel, E. S., Cohen, P. L. & Eisenberg, R. A. Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice. J. Exp. Med. 177, 69-78 (1993).
    • (1993) J. Exp. Med. , vol.177 , pp. 69-78
    • Reap, E.A.1    Sobel, E.S.2    Cohen, P.L.3    Eisenberg, R.A.4
  • 44
    • 0034695878 scopus 로고    scopus 로고
    • B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites
    • Paciorkowski, N., Porte, P., Shultz, L. D. & Rajan, T. V. B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites. J. Exp. Med. 191, 731-736 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 731-736
    • Paciorkowski, N.1    Porte, P.2    Shultz, L.D.3    Rajan, T.V.4
  • 45
    • 0034957380 scopus 로고    scopus 로고
    • Clearing the way to mechanisms of autoimmunity
    • Rosen, A. & Casciola-Rosen, L. Clearing the way to mechanisms of autoimmunity. Nature Med. 7, 664-665 (2001).
    • (2001) Nature Med. , vol.7 , pp. 664-665
    • Rosen, A.1    Casciola-Rosen, L.2
  • 46
    • 0023217559 scopus 로고
    • + B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice
    • + B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice. Eur. J. Immunol. 17, 521-528 (1987).
    • (1987) Eur. J. Immunol. , vol.17 , pp. 521-528
    • Forster, I.1    Rajewsky, K.2
  • 47
    • 0032787091 scopus 로고    scopus 로고
    • Control of early viral and bacterial distribution and disease by natural antibodies
    • Ochsenbein, A. F. et al. Control of early viral and bacterial distribution and disease by natural antibodies. Science 286, 2156-2159 (1999).
    • (1999) Science , vol.286 , pp. 2156-2159
    • Ochsenbein, A.F.1
  • 48
    • 0030014528 scopus 로고    scopus 로고
    • Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement
    • Weiser, M. R. et al. Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement. J. Exp. Med. 183, 2343-2348 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 2343-2348
    • Weiser, M.R.1
  • 49
    • 0033136629 scopus 로고    scopus 로고
    • Cutting edge: Protective response to pulmonary injury requires γδ T lymphocytes
    • King, D. P. et al. Cutting edge: protective response to pulmonary injury requires γδ T lymphocytes. J. Immunol. 162, 5033-5036 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 5033-5036
    • King, D.P.1
  • 50
    • 0031067995 scopus 로고    scopus 로고
    • An anti-inflammatory role for γδ T lymphocytes in acquired immunity to Mycobacterium tuberculosis
    • D'Souza, C. D. et al. An anti-inflammatory role for γδ T lymphocytes in acquired immunity to Mycobacterium tuberculosis. J. Immunol. 158, 1217-1221 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 1217-1221
    • D'Souza, C.D.1
  • 51
    • 0029825150 scopus 로고    scopus 로고
    • +-like thymocytes in the NOD mouse
    • +-like thymocytes in the NOD mouse. Eur. J. Immunol. 26, 2989-2998 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2989-2998
    • Gombert, J.M.1
  • 52
    • 0032495536 scopus 로고    scopus 로고
    • H1 bias of invariant Vα24JαQ T cells in type I diabetes
    • H1 bias of invariant Vα24JαQ T cells in type I diabetes. Nature 391, 177-181 (1998).
    • (1998) Nature , vol.391 , pp. 177-181
    • Wilson, S.B.1
  • 53
    • 0035810999 scopus 로고    scopus 로고
    • Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse
    • Shi, F. D. et al. Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc. Natl Acad. Sci. USA 98, 6777-6782 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6777-6782
    • Shi, F.D.1
  • 54
    • 0032489860 scopus 로고    scopus 로고
    • - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interteukin (IL)-4 and/or IL-10
    • - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interteukin (IL)-4 and/or IL-10. J. Exp. Med. 187, 1047-1056 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 1047-1056
    • Hammond, K.J.L.1
  • 55
    • 0032538904 scopus 로고    scopus 로고
    • Overexpression of natural killer T cells protects Vα14-Jα281 transgenic nonobese diabetic mice against diabetes
    • Lehuen, A. et al. Overexpression of natural killer T cells protects Vα14-Jα281 transgenic nonobese diabetic mice against diabetes. J. Exp. Med. 188, 1831-1839 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1831-1839
    • Lehuen, A.1
  • 56
    • 0034695880 scopus 로고    scopus 로고
    • Differential tumor surveillance by natural killer (NK) and NKT cells
    • Smyth, M. J. et al. Differential tumor surveillance by natural killer (NK) and NKT cells. J. Exp. Med 191, 661-668 (2000).
    • (2000) J. Exp. Med , vol.191 , pp. 661-668
    • Smyth, M.J.1
  • 57
    • 0034569025 scopus 로고    scopus 로고
    • NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
    • Terabe, M. et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nature Immunol. 1, 515-520 (2000).
    • (2000) Nature Immunol. , vol.1 , pp. 515-520
    • Terabe, M.1
  • 58
    • 0034606289 scopus 로고    scopus 로고
    • Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction
    • Dieli, F. et al. Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction. J. Exp. Med. 192, 1645-1652 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1645-1652
    • Dieli, F.1
  • 59
    • 0032729476 scopus 로고    scopus 로고
    • Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells
    • Carnaud, C. et al. Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J. Immunol. 163, 4647-4650 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 4647-4650
    • Carnaud, C.1
  • 60
    • 0033526066 scopus 로고    scopus 로고
    • The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interteukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells
    • Kitamura, H. et al. The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interteukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J. Exp. Med. 189, 1121-1128 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 1121-1128
    • Kitamura, H.1
  • 61
    • 0034680109 scopus 로고    scopus 로고
    • CD1-restricted T-cell responses and microbial infection
    • Park, S. H. & Bendelac, A. CD1-restricted T-cell responses and microbial infection. Nature 406, 788-792 (2000).
    • (2000) Nature , vol.406 , pp. 788-792
    • Park, S.H.1    Bendelac, A.2
  • 62
    • 0023690608 scopus 로고
    • Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors
    • Havran, W. L. & Allison, J. P. Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors. Nature 335, 443-445 (1988).
    • (1988) Nature , vol.335 , pp. 443-445
    • Havran, W.L.1    Allison, J.P.2
  • 63
    • 0028825461 scopus 로고
    • The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus
    • Zhang, Y. et al. The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus. Immunity 3, 439-447 (1995). Genetic dissection of the making of a canonical T-cell receptor.
    • (1995) Immunity , vol.3 , pp. 439-447
    • Zhang, Y.1
  • 64
    • 0027474344 scopus 로고
    • T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes
    • Itohara, S. et al. T cell receptor δ gene mutant mice: independent generation of αβ T cells and programmed rearrangements of γδ TCR genes. Cell 72, 337-348 (1993).
    • (1993) Cell , vol.72 , pp. 337-348
    • Itohara, S.1
  • 65
    • 0033136298 scopus 로고    scopus 로고
    • Increased functional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice
    • Benedict, C. L. & Kearney, J. F. Increased functional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice. Immunity 10, 607-617 (1999). Genetic dissection of the making of a canonical B-cell receptor.
    • (1999) Immunity , vol.10 , pp. 607-617
    • Benedict, C.L.1    Kearney, J.F.2
  • 66
    • 0028025074 scopus 로고
    • - T cells in mice and humans
    • - T cells in mice and humans. J. Exp. Med. 180, 1097-1106 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 1097-1106
    • Lantz, O.1    Bendelac, A.2
  • 68
    • 0030265684 scopus 로고    scopus 로고
    • Extrathymic origin of human γδ T cells during fetal development
    • McVay, L. D. & Carding, S. R. Extrathymic origin of human γδ T cells during fetal development. J. Immunol. 157, 2873-2882 (1996).
    • (1996) J. Immunol. , vol.157 , pp. 2873-2882
    • McVay, L.D.1    Carding, S.R.2
  • 69
    • 0025352593 scopus 로고
    • Evidence for extrathymic changes in the T cell receptor γ/δ repertoire
    • Parker, C. M. et al. Evidence for extrathymic changes in the T cell receptor γ/δ repertoire. J. Exp. Med. 171, 1597-1612 (1990).
    • (1990) J. Exp. Med. , vol.171 , pp. 1597-1612
    • Parker, C.M.1
  • 70
    • 0027538436 scopus 로고
    • Peripheral selection of antigen receptor junctional features in a major human γδ subset
    • Davodeau, F. et al. Peripheral selection of antigen receptor junctional features in a major human γδ subset. Eur. J. Immunol. 23, 804-808 (1993).
    • (1993) Eur. J. Immunol. , vol.23 , pp. 804-808
    • Davodeau, F.1
  • 71
    • 0033523728 scopus 로고    scopus 로고
    • Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity. J
    • Tatu, C., Ye, J., Arnold, L. W. & Clarke, S. H. Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity. J. Exp. Med. 190, 903-914 (1999).
    • (1999) Exp. Med. , vol.190 , pp. 903-914
    • Tatu, C.1    Ye, J.2    Arnold, L.W.3    Clarke, S.H.4
  • 72
    • 0033575778 scopus 로고    scopus 로고
    • B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development
    • Lam, K. P. & Rajewsky, K. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development. J. Exp. Med. 190, 471-477 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 471-477
    • Lam, K.P.1    Rajewsky, K.2
  • 73
    • 0034178253 scopus 로고    scopus 로고
    • + B cells both in vivo and in vitro
    • + B cells both in vivo and in vitro. J. Immunol. 164, 4586-4593 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 4586-4593
    • Chumley, M.J.1
  • 74
    • 0033973585 scopus 로고    scopus 로고
    • Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk
    • Martin, F. & Kearney, J. F. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk. Immunity 12, 39-49 (2000). A demonstration that specificity and avidity for self-antigen control the differentiation of innate lymphocytes.
    • (2000) Immunity , vol.12 , pp. 39-49
    • Martin, F.1    Kearney, J.F.2
  • 75
    • 0033567957 scopus 로고    scopus 로고
    • IL-4-producing γδ T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen
    • Gerber, D. J. et al. IL-4-producing γδ T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen. J. Immunol. 163, 3076-3082 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 3076-3082
    • Gerber, D.J.1
  • 76
    • 0029854221 scopus 로고    scopus 로고
    • Increased interleukin 4 and immunoglobulin e production in transgenic mice overexpressing NK1 T cells
    • Bendelac, A., Hunziker, R. D. & Lantz, O. Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells. J. Exp. Med. 184, 1285-1293 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 1285-1293
    • Bendelac, A.1    Hunziker, R.D.2    Lantz, O.3
  • 78
    • 0025273529 scopus 로고
    • Transgenic mice demonstrate that epithelial homing of γ/δ T cells is determined by cell lineages independent of T cell receptor specificity
    • Bonneville, M. et al. Transgenic mice demonstrate that epithelial homing of γ/δ T cells is determined by cell lineages independent of T cell receptor specificity. J. Exp. Med. 171, 1015-1026 (1990).
    • (1990) J. Exp. Med. , vol.171 , pp. 1015-1026
    • Bonneville, M.1
  • 79
    • 0033575755 scopus 로고    scopus 로고
    • Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment
    • Watanabe, N. et al. Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment. J. Exp. Med. 190, 461-469 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 461-469
    • Watanabe, N.1
  • 80
    • 0034691152 scopus 로고    scopus 로고
    • B cell receptor expression level determines the fate of developing B lymphocytes: Receptor editing versus selection
    • Kouskoff, V. Lacaud, G., Pape, K., Retter, M. & Nemazee, D. B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection. Proc. Natl Acad. Sci. USA 97, 7435-7439 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 7435-7439
    • Kouskoff, V.1    Lacaud, G.2    Pape, K.3    Retter, M.4    Nemazee, D.5
  • 81
    • 0034655136 scopus 로고    scopus 로고
    • Autoreactive B cells escape clonal deletion by expressing multiple antigen receptors
    • Kenny, J. J. et al. Autoreactive B cells escape clonal deletion by expressing multiple antigen receptors. J. Immunol. 164, 4111-4119 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 4111-4119
    • Kenny, J.J.1
  • 83
    • 0034610970 scopus 로고    scopus 로고
    • Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
    • Kennedy, M. K. et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191, 771-780 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 771-780
    • Kennedy, M.K.1
  • 84
    • 0028961264 scopus 로고
    • Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
    • Oyster, J. G. & Goodnow, C. C. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 2, 13-24 (1995).
    • (1995) Immunity , vol.2 , pp. 13-24
    • Oyster, J.G.1    Goodnow, C.C.2
  • 85
    • 0034053443 scopus 로고    scopus 로고
    • Development and function of B-1 cells
    • Hayakawa, K. & Hardy, R. R. Development and function of B-1 cells. Curr. Opin. Immunol. 12, 346-353 (2000).
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 346-353
    • Hayakawa, K.1    Hardy, R.R.2
  • 86
    • 0031036945 scopus 로고    scopus 로고
    • Effects of breeding environments on generation and activation of autoreactive B-1 cells in anti-red blood cell autoantibody transgenic mice
    • Murakami, M. et al. Effects of breeding environments on generation and activation of autoreactive B-1 cells in anti-red blood cell autoantibody transgenic mice. J. Exp. Med. 185, 791-794 (1997).
    • (1997) J. Exp. Med. , vol.185 , pp. 791-794
    • Murakami, M.1
  • 87
    • 0032995319 scopus 로고    scopus 로고
    • + T cells upon antigen expression in the thymus or in the liver
    • + T cells upon antigen expression in the thymus or in the liver. Eur. J. Immunol. 29, 2330-2343 (1999).
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2330-2343
    • Legendre, V.1
  • 89
    • 0027295654 scopus 로고
    • Evolution and pathophysiology of the human natural anti-α-galactosyl IgG (anti-Gal) antibody
    • Galili, U. Evolution and pathophysiology of the human natural anti-α-galactosyl IgG (anti-Gal) antibody. Springer Semin. Immunopathol. 15, 155-171 (1993).
    • (1993) Springer Semin. Immunopathol. , vol.15 , pp. 155-171
    • Galili, U.1
  • 90
    • 0023892588 scopus 로고
    • Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones
    • Liu, Y. J., Oldfield, S. & MacLennan, I. C. Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones. Eur. J. Immunol. 18, 355-362 (1988).
    • (1988) Eur. J. Immunol. , vol.18 , pp. 355-362
    • Liu, Y.J.1    Oldfield, S.2    MacLennan, I.C.3
  • 91
    • 0022556211 scopus 로고
    • Antigen-driven selection of virgin and memory B cells
    • MacLennan, I. C. & Gray, D. Antigen-driven selection of virgin and memory B cells. Immunol. Rev. 91, 61-85 (1986).
    • (1986) Immunol. Rev. , vol.91 , pp. 61-85
    • MacLennan, I.C.1    Gray, D.2
  • 92
    • 0022050744 scopus 로고
    • Immunoglobulin VH gene structure and diversity in Heterodontus, a phylogenetically primitive shark
    • Litman, G. W. et al. Immunoglobulin VH gene structure and diversity in Heterodontus, a phylogenetically primitive shark. Proc. Natl Acad. Sci. USA 82, 2082-2086 (1985).
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 2082-2086
    • Litman, G.W.1
  • 93
    • 0028201732 scopus 로고
    • Tolerance, danger and the extended family
    • Matzinger, P. Tolerance, danger and the extended family. Annu. Rev. Immunol. 12, 991-1045 (1994). A general model of immunity based on the assumption that sensing tissue stress and damage governs the decision between immunological tolerance versus responsiveness.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 94
    • 0032695108 scopus 로고    scopus 로고
    • Natural adjuvants: Endogenous activators of dendritic cells
    • Gallucci, S., Lolkema, M. & Matzinger, P. Natural adjuvants: endogenous activators of dendritic cells. Nature Med. 5, 1249-1255 (1999). A demonstration that necrotic, but not apoptotic, cell death activates the immune system.
    • (1999) Nature Med. , vol.5 , pp. 1249-1255
    • Gallucci, S.1    Lolkema, M.2    Matzinger, P.3
  • 95
    • 0033198183 scopus 로고    scopus 로고
    • H2 phenotype
    • H2 phenotype. J. Immunol. 163, 2373-2377 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 2373-2377
    • Singh, N.1
  • 96
    • 0034596944 scopus 로고    scopus 로고
    • Natural killer T cell activation inhibits hepatitis B virus replication in vivo
    • Kakimi, K., Guidotti, L. G., Koezuka, Y. & Chisari, F. V. Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J. Exp. Med. 192, 921-930 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 921-930
    • Kakimi, K.1    Guidotti, L.G.2    Koezuka, Y.3    Chisari, F.V.4
  • 97
    • 12944255911 scopus 로고    scopus 로고
    • α-galactosylceramide-activated Vα14 natural killer T cells mediate protection against murine malaria
    • Gonzalez-Aseguinolaza, G. et al. α-galactosylceramide-activated Vα14 natural killer T cells mediate protection against murine malaria. Proc. Natl Acad. Sci. USA 97, 8461-8466 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 8461-8466
    • Gonzalez-Aseguinolaza, G.1
  • 98
    • 0033197917 scopus 로고    scopus 로고
    • Cutting edge: Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide
    • Toura, I. et al. Cutting edge: inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide. J. Immunol. 163, 2387-2391 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 2387-2391
    • Toura, I.1
  • 99
    • 0034786013 scopus 로고    scopus 로고
    • The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in nonobese diabetic mice
    • Hong, S. et al. The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in nonobese diabetic mice. Nature Med. 7, 1052-1056 (2001).
    • (2001) Nature Med. , vol.7 , pp. 1052-1056
    • Hong, S.1
  • 100
    • 0034799397 scopus 로고    scopus 로고
    • Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
    • Sharif, S. et al. Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nature Med. 7, 1057-1062 (2001).
    • (2001) Nature Med. , vol.7 , pp. 1057-1062
    • Sharif, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.