Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide

European Journal of Immunology

Volumn 31, Issue 6, 2001, Pages 1720-1727

  Hayakawa, Yoshihiro ^a   Takeda, Kazuyoshi ^b   Yagita, Hideo ^c   Kakuta, Shigeru ^d   Iwakura, Yoichiro ^a   Van Kaer, Luc ^b   Saiki, Ikuo ^c   Okumura, Ko ^a,e  

^a UNIVERSITY OF TOYAMA   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Galactosylceramide; IFN ; NK cell; NKT cell; Tumor

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1 ANTIGEN; GALACTOSYLCERAMIDE; GAMMA INTERFERON; GLYCOLIPID; INTERLEUKIN 4; PERFORIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG CYTOTOXICITY; DRUG POTENCY; IN VITRO STUDY; IN VIVO STUDY; INTERFERON PRODUCTION; LIVER CELL; METASTASIS INHIBITION; MONONUCLEAR CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN SECRETION; SPLEEN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CYTOTOXICITY, IMMUNOLOGIC; GALACTOSYLCERAMIDES; INTERFERON TYPE II; INTERLEUKIN-4; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES; TIME FACTORS;

EID: 0034970326     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200106)31:6<1720::AID-IMMU1720>3.0.CO;2-U     Document Type: Article

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