NKT cells are relatively resistant to apoptosis

Trends in Immunology

Volumn 25, Issue 5, 2004, Pages 219-221

  Seino, Ken Ichiro ^a   Harada, Michishige ^a   Taniguchi, Masaru ^a  

^a RIKEN YOKOHAMA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CELL ACTIVATION; CELL POPULATION; DOWN REGULATION; HUMAN; IMMUNE SYSTEM; IMMUNOSTIMULATION; NATURAL KILLER CELL; NONHUMAN; PROTEIN FUNCTION; REGULATORY MECHANISM; SHORT SURVEY;

ANIMALS; ANTIGENS; ANTIGENS, SURFACE; APOPTOSIS; CELL DIFFERENTIATION; DOWN-REGULATION; FORECASTING; GALACTOSYLCERAMIDES; GENE EXPRESSION REGULATION; HUMANS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; PROTEINS; RECEPTORS, ANTIGEN; THYMUS GLAND;

EID: 12744268685     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2004.03.001     Document Type: Short Survey

References (22)

1. Taniguchi M., et al. The regulatory role of Vα14NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 21:2003;483-513.
2. Kronenberg M., Gapin L. The unconventional lifestyle of NKT cells. Nat. Rev. Immunol. 2:2002;557-568.
3. Pellicci D.G., et al. Intrathymic NKT cell development is blocked by the presence of α-galactosylceramide. Eur. J. Immunol. 33:2003;1816-1823.
4. Wilson M.T., et al. The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proc. Natl. Acad. Sci. U. S. A. 100:2003;10913-10918.
5. Crowe N.Y., et al. Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells. J. Immunol. 171:2003;4020-4027.
6. Harada M., et al. Down-regulation of invariant Vα14 antigen receptor in NKT cells upon activation. Int. Immunol. 16:2004;241-247.
7. Kawano T., et al. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science. 278:1997;1626-1629.
8. Sidobre S., et al. The Vα14 NKT cell TCR exhibits high-affinity binding to a glycolipid-CD1d complex. J. Immunol. 169:2002;1340-1348.
9. Chun T., et al. CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J. Exp. Med. 197:2003;907-918.
10. Hong S., et al. Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice. Immunol. Rev. 169:1999;31-44.
11. Eberl G., MacDonald H.R. Rapid death and regeneration of NKT cells in anti-CD3ε- or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis. Immunity. 9:1998;345-353.
12. Leite-de-Moraes M.C., et al. Fas/Fas ligand interactions promote activation-induced cell death of NK T lymphocytes. J. Immunol. 165:2000;4367-4371.
13. Yusuf I., Fruman D.A. Regulation of quiescence in lymphocytes. Trends Immunol. 24:2003;380-386.
14. Walunas T.L., et al. Cutting edge: the Ets1 transcription factor is required for the development of NK T cells in mice. J. Immunol. 164:2000;2857-2860.
15. Banz A., et al. Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells. J. Immunol. 169:2002;750-757.
16. + suppressor T cells in vivo. Nat. Immunol. 3:2002;33-41.
17. Bluestone J.A., Abbas A.K. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3:2003;253-257.
18. + regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2:2001;301-306.
19. Bendelac A., et al. Autoreactivity by design: innate B and T lymphocytes. Nat. Rev. Immunol. 1:2001;177-186.
20. Poussier P., et al. A unique subset of self-specific intra-intestinal T cells maintains gut integrity. J. Exp. Med. 195:2002;1491-1497.
21. + T cells are positively selected in the thymus by agonist self-peptides. Immunity. 16:2002;355-364.
22. Lenardo M., et al. Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17:1999;221-253.