Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells

European Journal of Immunology

Volumn 30, Issue 4, 2000, Pages 985-992

  Eberl, Gérard ^a   MacDonald, H Robson ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Cytotoxicity; Innate immunity; NK cell; NKT cell; Proliferation

Indexed keywords

ANTIGEN; CD1 ANTIGEN; CELL MARKER; GALACTOSYLCERAMIDE; GAMMA INTERFERON; GLYCOLIPID; INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; FEMALE; LIVER; LYMPHOCYTE PROLIFERATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD1; B-LYMPHOCYTES; CELL DIVISION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; FEMALE; GALACTOSYLCERAMIDES; INTERFERON TYPE II; INTERLEUKIN-12; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; SPLEEN; T-LYMPHOCYTES;

EID: 0034002676     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(200004)30:4<985::AID-IMMU985>3.0.CO;2-E     Document Type: Article

References (46)

1. Bendelac, A., Rivera, M. N., Park, S. H. and Roark, J. H., Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 1997. 15: 535-562.
2. + cells: new clues to their origin, specificity, and function. J. Exp. Med. 1995. 182: 633-638.
3. + T cells. J. Exp. Med. 1998. 187: 2109-2114.
4. - T cells in mice and humans. J. Exp. Med. 1994. 180: 1097-1106.
5. + cells in mouse liver. J. Exp. Med. 1996. 183: 1277-1282.
6. - single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor Vβ family. Proc. Natl. Acad. Sci. USA 1992. 89: 6506-6510.
7. + cells in the liver of mice. J. Exp. Med. 1994. 180: 699-704.
8. + T lymphocytes. Science 1995. 268: 863-865.
9. Brossay, L., Chioda, M., Burdin, N., Koezuka, Y., Casorati, G., Dellabona, P. and Kronenberg, M., CD1 d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J. Exp. Med. 1998. 188: 1521-1528.
10. Spada, F. M., Koezuka, Y. and Porcelli, S. A., CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J. Exp. Med. 1998. 188: 1529-1534.
11. Zeng, Z., Castano, A. R., Segelke, B. W., Stura, E. A., Peterson, P. A. and Wilson, I. A., Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. Science 1997. 277: 339-345.
12. Joyce, S., Woods, A. S., Yewdell, J. W., Bennink, J. R., Dharshan De Silva, A., Boesteanu, A., Balk, S. P., Cotter, R. J. and Brutkiewicz, R. R., Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science 1998. 279: 1541-1544.
13. Kawano, T., Cui, J., Koezuka, Y., Toura, I., Kaneko, Y., Motoki, K., Ueno, H., Nakagawa, R., Sato, H., Kondo, E., Koseki, H. and Taniguchi, M., CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science 1997. 278: 1626-1629.
14. + NK T lymphocytes. J. Immunol. 1998. 161: 3271-3281.
15. Schofield, L., McConville, M. J., Hansen, D., Campbell, A. S., Fraser-Reid, B., Grusby, M. J. and Tachado, S. D., CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells. Science 1999. 283: 225-229.
16. Apostolou, I., Takahama, Y., Belmant, C., Kawano, T., Huerre, M., Marchal, G., Cui, J., Taniguchi, M., Nakauchi, H., Fournié, J.-J. and Gachelin, G., Murine Natural Killer T cells contribute to the granulomatous reaction caused by mycobacterial cell walls. Proc. Natl. Acad. Sci. USA 1999. 96: 5141-5146.
17. + T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 1994. 179: 1285-1295.
18. - thymocytes with specific lymphokine secretion. Eur. J. Immunol. 1993. 23: 307-310.
19. + T cells upon NKR-P1 crosslinking. J. Exp. Med. 1996. 183: 2391-2396.
20. + T cells produce large amounts of IL-4 and IFN-γ upon activation by anti-CD3 or CD1. J. Immunol. 1997. 159: 2240-2249.
21. - (NKT) thymocytes prevent insulin dependent diabetes mellitus in NOD/Lt mice by the influence of IL-4 and/or IL-10. J. Exp. Med. 1998. 187: 1047-1056.
22. Lehuen, A., Lantz, O., Beaudoin, L., Laloux, V., Carnaud, C., Bendelac, A., Bach, J. F. and Monteiro, R. C., Overexpression of natural killer T cells protects Vα14-Jα281 transgenic nonobese diabetic mice against diabetes. J. Exp. Med. 1998. 188: 1831-1839.
23. Sumida, T., Sakamoto, A., Murata, H., Makino, Y., Takahashi, H., Yoshida, S., Nishioka, K., Iwamoto, I. and Taniguchi, M., Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis. J. Exp. Med. 1995. 182: 1163-1168.
24. Wilson, S. B., Kent, S. C., Patton, K. T., Orban, T., Jackson, R. A., Exley, M., Porcelli, S., Schatz, D. A., Atkinson, M. A., Balk, S. P., Strominger, J. L. and Hafler, D. A., Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes. Nature 1998. 391: 177-181.
25. Bendelac, A., Hunziker, R. D.and Lantz, O., Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells. J. Exp. Med. 1996. 184: 1285-1293.
26. Burdin, N., Brossay, L. and Kronenberg, M., Immunization with α-galactosylceramide polarizes CD1-reactive NKT cells towards Th2 cytokine synthesis. Eur. J. Immunol. 1999. 29: 2014-2025.
27. Singh, N., Hong, S., Scherer, D. C., Serizawa, I., Burdin, N., Kronenberg, M., Koezuka, Y. and Van Kaer, L., Activation of NKT cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J. Immunol. 1999. 163: 2373-2377.
28. Kobayashi, E., Motoki, K., Uchida, T., Fukushima, H. and Koezuka, Y., KRN7000, a novel immunomodulator, and its antitumor activities. Oncology Res. 1995. 7: 529-534.
29. Nakagawa, R., Motoki, K., Ueno, H., Iijima, R., Nakamura, H., Kobayashi, E., Shimosaka, A. and Koezuka, Y., Treatment of hepatic metastasis of the colon26 adenocarcinoma with an α-galactosylceramide, KRN7000. Cancer Res. 1998. 58: 1202-1207.
30. Kawano, T., Cui, J., Koezuka, Y., Toura, I., Kaneko, Y., Sato, H., Kondo, E., Harada, M., Koseki, H., Nakayama, T., Tanaka, Y. and Taniguchi, M., Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells. Proc. Natl. Acad. Sci. USA 1998. 95: 5690-5693.
31. Cui, J., Shin, T., Kawano, T., Sato, H., Kondo, E., Toura, I., Kaneko, Y., Koseki, H., Kanno, M. and Taniguchi, M., Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 1997. 278: 1623-1626.
32. + αβ T cells with intermediate TCR induced in the liver of mice by IL-12. J. Immunol. 1995. 154: 4333-4340.
33. + αβ T cells activated by IL-12 as a major effector in inhibition of experimental tumor metastasis. J. Immunol. 1996. 156: 3366-3373.
34. Eberl, G. and MacDonald, H. R., Rapid death and regeneration of NKT cells in anti-CD3ε or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis. Immunity 1998. 9: 345-353.
35. Eberl, G., Lees, R., Smiley, S. T., Taniguchi, M., Grusby, M. J. and MacDonald, H. R., Tissue-specific segregation of CD1d-dependent and CD1d-independent NKT cells. J. Immunol. 1999. 162: 6410-6419.
36. Kitamura, H., Iwakabe, K., Yahata, T., Nishimura, S., Ohta, A., Ohmi, Y., Sato, M., Takeda, K., Okumura, K., Van Kaer, K., Kawano, T., Taniguchi, M. and Nishimura, T., The Natural killer (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J. Exp. Med. 1999. 189: 1121-1127.
37. +NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system. J. Immunol. 1999. 163: 93-101.
38. Biron, C. A., Nguyen, K. B., Pien, G. C., Cousens, L. P. and Salazar-Mather, T. P., Natural Killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 1999. 17: 189-220.
39. Lodolce, J. P., Boone, D. L., Chai, S., Swain, R. E., Dassopoulos, T., Trettin, S. and Ma, A., IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998. 9: 669-676.
40. Ogasawara, H., Hida, S., Azimi, N., Tagaya, Y., Sato, T., Yokochi-Fukuda, T., Waldmann, T. A., Taniguchi, T. and Taki, S., Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 1998. 391: 700-703.
41. Carnaud, C., Lee, D., Donnars, O., Park, S.-H., Beavis, A., Koezuka, Y. and Bendelac, A., Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J. Immunol. 1999. 163: 4647-4650.
42. Watanabe, K., Matsubara, T. and Hakomori, S., α-L-Fucopyranosylceramide, a novel glycolipid accumulated in some of the human colon tumors. J. Biol. Chem. 1976. 251: 2385-2387.
43. Unanue, E. R., Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance. Curr. Opin. Immunol. 1997. 9: 35-43.
44. Whiteside, T. L. and Herberman, R. B., The role of natural killer cells in immune surveillance of cancer. Curr. Opin. Immunol. 1995. 7: 704-710.
45. Morita, M., Natori, T., Akimoto, K., Osawa, T., Fukushima, H. and Koezuka, Y., Syntheses of α-, β-monoglycosylceramides and four diastomers of an α-galactosylceramide. Bioorg. Med. Chem. Lett. 1995. 5: 699-704.
46. Gresser, I., Tovey, M. G., Bandu, M.-T., Maury, C. and BrotyBoye, D., Role of interferon in the pathogenesis of virus disease in mice as demonstrated by the use of anti-interferon serum. I. Rapid evolution of encephalomyelitis virus infection. J. Exp. Med. 1976. 144: 1305-1315.