Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

Nature

Volumn 434, Issue 7032, 2005, Pages 525-529

  Mattner, Jochen ^a   DeBord, Kristin L ^a   Ismail, Nahed ^b   Goff, Randal D ^c   Cantu III, Carlos ^d   Zhou, Dapeng ^a   Saint Mezard, Pierre ^a   Wang, Vivien ^a   Gao, Ying ^c   Yin, Ning ^c   Hoebe, Kasper ^d   Schneewind, Olaf ^a   Walker, David ^b   Beutler, Bruce ^d   Teyton, Luc ^d   Savage, Paul B ^c   Bendelac, Albert ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c Brigham Young University   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; BACTERIA; LIPIDS; POLYSACCHARIDES;

NATURAL KILLER T (NKT) CELLS; PATHOGENS; SEPTIC SHOCK REACTIONS; T-CELL RECEPTORS;

CELLS;

ANTIGEN; CD1D ANTIGEN; CERAMIDE; GAMMA INTERFERON; GLYCOLIPID; GLYCOSPHINGOLIPID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; LIPID; LIPOPOLYSACCHARIDE; T LYMPHOCYTE RECEPTOR; BACTERIAL ANTIGEN; CD1 ANTIGEN;

IMMUNE SYSTEM;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DENDRITIC CELL; EHRLICHIA; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFECTION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SALMONELLA TYPHIMURIUM; SPHINGOMONAS; T LYMPHOCYTE; ANIMAL; CELL CULTURE; CELL WALL; CHEMISTRY; DRUG EFFECT; GENETICS; GRAM NEGATIVE INFECTION; IMMUNOLOGY; ISOLATION AND PURIFICATION; LYMPHOCYTE ACTIVATION; MICROBIOLOGY; SEPTIC SHOCK; SPLEEN; SYNTHESIS; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, CD1; CELL WALL; CELLS, CULTURED; CERAMIDES; DENDRITIC CELLS; EHRLICHIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; KILLER CELLS, NATURAL; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; SALMONELLA TYPHIMURIUM; SHOCK, SEPTIC; SPHINGOMONAS; SPLEEN; T-LYMPHOCYTE SUBSETS;

EID: 20144389877     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03408     Document Type: Article

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