Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis

European Journal of Immunology

Volumn 29, Issue 6, 1999, Pages 2014-2025

  Burdin, Nicolas ^a   Brossay, Laurent ^a   Kronenberg, Mitchell ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

Antigen presentation; CD1; Glycolipid; T lymphocyte; Th1; Th2

Indexed keywords

CD1 ANTIGEN; GALACTOSYLCERAMIDE; GAMMA INTERFERON; GLYCOPHOSPHOLIPID; INTERLEUKIN 10; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CYTOKINE RELEASE; IMMUNE RESPONSE; IMMUNIZATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN LYMPHOCYTE; T LYMPHOCYTE;

EID: 0033022704     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199906)29:06<2014::AID-IMMU2014>3.0.CO;2-G     Document Type: Article

References (58)

1. Zeng, Z. H., Castaño, A. R., Segelke, B., Stura, E. A., Peterson, P. A. and Wilson, I. A., The crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 1997. 277: 339-345.
2. Brossay, L., Jullien, D., Cardell, S., Sydora, B. C., Burdin, N., Modlin, R. L. and Kronenberg, M., mCD1 is mainly expressed on hemopoietic derived cells. J. Immunol. 1997. 159: 1216-1224.
3. Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M. and Bendelac, A., CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells. J. Immunol. 1998. 160: 3121-3127.
4. Porcelli, S. A., The CD1 family: a third lineage of antigen-presenting molecules. Adv. Immunol. 1995. 59: 1-98.
5. Maher, J. K. and Kronenberg, M., The role of CD1 molecules in immune responses to infection. Curr. Opin. Immunol. 1997. 9: 456-461.
6. Bendelac, A., Rivera, M. N., Park, S. H. and Roark, J. H., Mouse CD1-specific NK1 T cells: development, specificity and function. Annu. Rev. Immunol. 1997. 15: 535-562.
7. Brossay, L., Burdin, N., Tangri, S. and Kronenberg, M., Antigen presenting function of mCD1: one molecule with two different kinds of antigenic ligands. Immunol. Rev. 1998. 163: 139-150.
8. Castaño, A. R., Tangri, S., Miller, J. E., Holcombe, H. R., Jackson, M. R., Huse, W. D., Kronenberg, M. and Peterson, P. A., Peptide binding and presentation by mouse CD1. Science 1995. 269: 223-226.
9. Lee, D. J., Abeyratne, A., Carson, D. A. and Corr, M., Induction of an antigen-specific CD1-restricted cytotoxic T lymphocyte response in vivo. J. Exp. Med. 1998. 187: 433-438.
10. Tangri, S., Brossay, L., Burdin, N., Lee, D. J., Corr, M. and Kronenberg, M., Presentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processing. Proc. Natl. Acad. Sci. USA 1998. 95: 14314-14319.
11. Ernst, W. A., Maher, J., Cho, S., Niazi, K. R., Chatterjee, D., Moody, B. D., Besra, G. S., Watanabe, Y., Jensen, P. E., Porcelli, S. A., Kronenberg, M. and Modlin, R. L., Molecular interaction of CD1b with lipoglycan antigens. Immunity 1998. 8: 331-340.
12. Porcelli, S. A., Segelke, B. W., Sugita, M., Wilson, I. A. and Brenner, M. B., The CD1 family of lipid antigen-presenting molecules. Immunol. Today 1998. 19: 362-368.
13. + T cells. Nature 1994. 372: 691-694.
14. Sieling, P. A., Chatterjee, D., Porcelli, S. A., Prigozy, T. I., Mazzaccaro, R. J., Soriano, T., Bloom, B. R., Brenner, M. B., Kronenberg, M., Brennan, P. J. and Modlin, R. L., CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 1995. 269: 227-230.
15. Moody, D. B., Reinhold, B. B., Guy, M. R., Beckman, E. M., Frederique, D. E., Furlong, S. T., Ye, S., Reinhold, V. N., Sieling, P. A., Modlin, R. L., Besra, G. S. and Porcelli, S. A., Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science 1997. 278: 283-286.
16. Stenger, S., Mazzaccaro, R. J., Uyemura, K., Cho, S., Barnes, P. F., Rosat, J. P., Sette, A., Brenner, M. B., Porcelli, S. A., Bloom, B. R. and Modlin, R. L., Differential effects of cytolytic T cell subsets on intracellular infection. Science 1997. 276: 1684-1687.
17. Joyce, S., Woods, A. S., Yewdell, J. W., Bennink, J. R., De Silva, A. D., Boesteanu, A., Balk, S. P., Cotter, R. J. and Brutkiewicz, R. R., Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science 1998. 279: 1541-1544.
18. Kawano, T., Cui, J., Koezuka, Y., Toura, I., Kaneko, Y., Motoki, K., Ueno, H., Nakagawa, R., Sato, H., Kondo, E., Koseki, H. and Taniguchi, M., CD1d-restricted and TCR-mediated activation of Vα14 NK T cells by glycosylceramides. Science 1997. 278: 1626-1629.
19. Burdin, N., Brossay, L., Koezuka, Y., Smiley, S. T., Grusby, M. J., Gui, M., Taniguchi, M., Hayakawa, K. and Kronenberg, M., Selective ability of mouse CD1 to present glycolipids: α-galactosylceramide specifically stimulates Vα14 NK T lymphocytes. J. Immunol. 1998. 161: 3271-3281.
20. Schofield, L., McConville, M., Hansen, D., Campbell, S., Fraser-Reid, B., Grusby, M. J. and Tachado, S. D., CD1d-restricted IgG formation to GPI-anchored antigens mediated by NK T cells. Science 1999. 283: 225-229.
21. + NK T cells: a novel lymphoid cell lineage with regulatory function. J. Allergy Clin. Immunol. 1996. 263-269.
22. Burdin, N. and Kronenberg, M., CD1 mediated immune responses to glycolipid antigen. Curr. Opin. Immunol. 1999. 11, in press.
23. + targets. J. Immunol. 1998. 160: 3681-3688.
24. Park, S. H., Roark, J. H. and Bendelac, A., Tissue-specific recognition of mouse CD1 molecules. J. Immunol. 1998. 160: 3128-3134.
25. Brossay, L., Naidenko, O., Burdin, N., Matsuda, J., Sakai, T. and Kronenberg, M., Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells. J. Immunol. 1998. 161: 5124-5128.
26. - T cells. J. Exp. Med. 1997. 186: 109-120.
27. Davodeau, F., Peyrat, M. A., Necker, A., Dominici, R., Blanchard, F., Leget, C., Gaschet, J., Costa, P., Jacques, Y., Godard, A., Vie, H., Poggi, A., Romagne, F. and Bonneville, M., Close phenotypic and functional similarities between human and murine αβ T cells expressing invariant TCR α-chains. J. Immunol. 1997. 158: 5603-5611.
28. - T cells. J. Exp. Med. 1994. 180: 1171-1176.
29. Brossay, L., Chioda, M., Burdin, N., Koezuka, Y., Casorati, G., Dellabona, P. and Kronenberg, M., CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J. Exp. Med. 1998. 188: 1521-1528.
30. Spada, F. M., Koezuka, Y. and Porcelli, S. A., CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J. Exp. Med. 1998. 188: 1529-1534.
31. Couedel, C., Peyrat, M. A., Brossay, L., Koezuka, Y., Porcelli, S. A., Davodeau, F. and Bonneville, M., Diverse CD1d-restricted reactivity patterns of human T cells bearing "invariant" AV24BV11 TCR. Eur. J. Immunol. 1998. 28: 4391-4397.
32. Eberl, G. and MacDonald, H. R., Rapid death and regeneration of NK T cells in anti-CD3ε- or IL-12-treated mice: a major role for bone marrow in NK T cell homeostasis. Immunity 1998. 9: 345-353.
33. Yamaguchi, Y., Motoki, K., Ueno, H., Maeda, K., Kobayashi, E., Inoue, H., Fukushima, H. and Koezuka, Y., Enhancing effects of (2S,3S,4R)-1-O-(α-D-galactopyranosyl)-2-(N-hexacosanoylamino)-1,3,4- octadecanetriol (KRN7000) on antigen-presenting function of antigen-presenting cells and antimetastatic activity of KRN7000-pretreated antigen-presenting cells. Oncol. Res. 1996. 8: 399-407.
34. + T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 1994. 179: 1285-1295.
35. + T cells upon NKR-P1 cross-linking. J. Exp. Med. 1996. 183: 2391-2396.
36. + T cells and their IFN-γ production in the generalized Shwartzman reaction. J. Immunol. 1998. 160: 3522-3527.
37. + T cells are resistant to glucocorticoid-induced apoptosis: implications for the Th1/Th2 balance. J. Immunol. 1998. 161: 1239-1247.
38. + T cells in a TH2 response and in immunoglobulin E production. Science 1995. 270: 1845-1847.
39. Bendelac, A., Hunziker, R. D. and Lantz, O., Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells. J. Exp. Med. 1996. 184: 1285-1293.
40. + T lymphocytes requires early IL-4 production by αβ T lymphocytes carrying invariant Vα14 TCR α chains. Int. Immunol. 1998. 10: 413-420.
41. Zhang, Y., Rogers, K. H. and Lewis, D, B., β2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses. J. Exp. Med. 1996. 184: 1507-1512.
42. Smiley, S. T., Kaplan, M. H. and Grusby, M. J., Immunoglobulin E production in the absence of Interleukin-4-secreting CD1-dependent cells. Science 1997. 275: 977-979.
43. Mendiratta, S. J., Martin, W. D., Hong, S., Boesteanu, A., Joyce, S. and Van Kaer, L., CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 1997. 6: 469-477.
44. + T cell development and early IL-4 production in CD1-deficient mice. Immunity 1997. 6: 459-467.
45. + cells as effectors of IFN-γ dependent immunity to Toxoplasma gondii in MHC class I-deficient mice. J. Exp. Med. 1993. 178: 1465-1472.
46. - αβ T cells in the peritoneal cavity: specific T cell receptor-mediated cytotoxicity and selective IFN-γ production against B cell leukemia and myeloma cells. J. Immunol. 1996. 157: 3925-3935.
47. - cells: implications for the regulation of Th1- and Th2-1ype responses. Int. Immunol. 1997. 9: 1123-1129.
48. Exley, M., Porcelli, S., Furman, M., Garcia, J. and Balk, S., CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Vα24JαQ T cell receptor a chains. J. Exp. Med. 1998. 188: 867-876.
49. Sumida, T., Sakamoto, A., Murata, H., Makino, Y., Takahashi, H., Yoshida, S., Nishioka, K., Iwamoto, I. and Taniguchi, M., Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis. J. Exp. Med 1995. 182: 1163-1168.
50. + T cell-defective IL-4 production in the non-obese diabetic mouse. Int. Immunol. 1996. 8: 1751-1758.
51. Wilson, S. B., Kent, S. C., Patton, K. T., Orban, T., Jackson, R. A., Exley, M., Porcelli, S., Schatz, D. A., Atkinson, M. A., Balk, S. P., Strominger, J. L. and Hafter, D. A., Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes. Nature 1998. 391: 177-181.
52. Zeng, D., Dick, M., Cheng, L., Amano, M., Dejbakhsh-Jones, S., Huie, P., Sibley, R. and Strober, S., Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: role of cytokines. J. Exp. Med. 1998. 187: 525-536.
53. Cut, J., Shin, T., Kawano, T., Sato, H., Kondo, E., Toura, I., Kaneko, Y., Koseki, H., Kanno, M. and Taniguchi, M., Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 1997. 278: 1623-1626.
54. Kawano, T., Cui, J., Koezuka, Y., Toura, I., Kaneko, Y., Sato, H., Kondo, E., Harada, M., Koseki, H., Nakayama, T., Tanaka, Y. and Taniguchi, M., Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells. Proc. Natl. Acad. Sci. USA 1998. 95: 5690-5693.
55. Kobayashi, E., Motoki, K., Uchida, T., Fukushima, H. and Koezuka, Y., KRN7000, a novel immunomodulator, and its antitumor activities. Oncol. Res. 1995. 7: 529-534.
56. Nakagawa, R., Motoki, K., Ueno, H., Iijima, R., Nakamura, H., Kobayashi, E., Shimosaka, A. and Koezuka, Y., Treatment of hepatic metastasis of the colon 26 adenocarcinoma with an α-galactosylceramide, KRN7000. Cancer Res. 1998. 58: 1202-1207.
57. - (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10. J. Exp. Med. 1998. 187: 1047-1056.
58. Morita, M., Natori, T., Akimoto, K., Osawa, T., Fukushima, H. and Koezuka, Y., Syntheses of α-, β-monoglycosylceramides and four diastereomers of an α-galactosylceramide. Bioorg. Med. Chem. Lett. 1995. 5: 699-704.