Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: Critical role for B7 in CD1d-dependent NKT cell interferon γ production

Journal of Experimental Medicine

Volumn 194, Issue 8, 2001, Pages 1179-1186

  Ikarashi, Y ^a   Mikami, R ^a   Bendelac, A ^a   Terme, M ^a   Chaput, N ^a   Terada, M ^a   Tursz, T ^a   Angevin, E ^a   Lemonnier, F A ^a   Wakasugi, H ^a   Zitvogel, L ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

CD1d; Costimulation; IFN ; Inhibitory receptors; NKT cells

Indexed keywords

B7 ANTIGEN; CD1 ANTIGEN; CD28 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN GP 39; INTERLEUKIN 12; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; BONE MARROW; CELL ACTIVATION; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; H2 SYSTEM; IMMUNE RESPONSE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; TH1 CELL;

ANIMALS; ANTIGENS; ANTIGENS, CD1; ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, SURFACE; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; H-2 ANTIGENS; INTERFERON TYPE II; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0035887526     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.8.1179     Document Type: Article

References (32)

1. + T cells: Development, specificity, and function
2. + T cell receptor α/β cells: New clues to their origin, specificity and function
3. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides
4. CD1d-restricted recognition of synthetic glycolipid antigen by human natural killer T cell
5. Selective ability of mouse CD1 to present glycolipids α-galactosylceramide specifically stimulates Vα14 NKT lymphocytes
6. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumor
7. Natural killer-like nonspecific tumor lysis mediated by specific ligand-activated Voα14 NKT cells
8. Differential tumor surveillance by natural killer (NK) and NKT cells
9. The antitumor activity of IL-12: Mechanisms of innate immunity that are model and dose-dependent
10. Antitumor activity of α-galactosylceramide, KRN7000, in mice with EL-4 hepatic metastasis and its cytokine production
11. Extreme Th1 bias of invariant Vα24jaQT cells in type 1 diabetes
12. The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 producing by dendritic cell and IL-12 receptor expression on NKT cells
13. Immunization with α-galactosylceramide polarizes CD1d-reactive NK T cells towards Th2 cytokine synthesis
14. Role of NK1.1 + T cells in a Th2 response and in IgE production
15. NKT cell-immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
16. Murine CD1d-restricted T cell recognition of cellular lipids
17. + targets
18. Tissue-specific recognition of mouse CD1 molecules
19. Distinct subset of CD1d-restricted T cells recognize self-antigen loaded in different cellular compartments
20. Dendritic cells directly trigger NK cell function: Cross-talk relevant in innate anti-tumor immune responses in vivo
21. + T cells and natural killer cells
22. + intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and non classical CD1 molecules
23. Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1+ and - Mouse strains
24. Cytokines production of U5A2-13-positive T cells by stimulation with glycolipid α-galactosylceramide
25. + T cells
26. + T cells
27. b
28. Analysis of Qa-1(b) peptide binding specificity and capacity of CD94/NKG2A to discriminate between Qa-1-peptide complexes
29. Natural adjuvants: Endogenous activators of dendritic cells
30. Tissue-specific segregation of CD1d-dependent and CD1d independent NKT cells
31. + lymphoid dendritic cells
32. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice