Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis

Stem Cells

Volumn 23, Issue 7, 2005, Pages 879-894

  Kucia, Magda ^a   Reca, Rvan ^a   Miekus, Katarzyna ^b   Wanzeck, Jens ^a   Wojakowski, Wojtek ^b   Janowska Wieczorek, Anna ^c   Ratajczak, Janina ^a   Ratajczak, Mariusz Z ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

CXCR4; Homing; Metastasis; SDF 1; Stem cells

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; FIBRINOGEN; FIBRONECTIN; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE 2; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; JANUS KINASE; MEMBRANE LIPID; MITOGEN ACTIVATED PROTEIN KINASE 1; PAXILLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE LCK; PROTEIN KINASE LYN; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; RANTES; STAT PROTEIN; STROMAL CELL DERIVED FACTOR 1; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VAV PROTEIN;

BONE METASTASIS; CANCER CELL; CELL ADHESION; CELL MOTILITY; CELL PROLIFERATION; CELL SURFACE; CELL SURVIVAL; CELL TRANSPORT; CELL TYPE; CHEMOTAXIS; HEMATOPOIETIC STEM CELL; HUMAN; INFLAMMATION; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; METASTASIS; NONHUMAN; POSTNATAL DEVELOPMENT; PROTEIN EXPRESSION; REVIEW; TISSUE DISTRIBUTION; TISSUE REGENERATION;

ANIMALS; BONE MARROW; BONE MARROW CELLS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CHEMOKINES, CXC; CHEMOTAXIS; HUMANS; INFLAMMATION; LIGANDS; MEMBRANE MICRODOMAINS; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; NEOPLASMS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; STEM CELLS; TISSUE DISTRIBUTION;

EID: 23844513413     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2004-0342     Document Type: Review

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