Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells

Oncogene

Volumn 22, Issue 50, 2003, Pages 8093-8101

  Burger, Meike ^a   Glodek, Aleksandra ^b   Hartmann, Tanja ^a   Schmitt Gräff, Anette ^a   Silberstein, Leslie E ^b   Fujii, Nobutaka ^c   Kipps, Thomas J ^d   Burger, Jan A ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c KYOTO UNIVERSITY   (Japan)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Adhesion; Chemokine receptor; Integrin activation; Lung cancer; Migration; Signal transduction

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CS 1 PEPTIDE; INTEGRIN; PERTUSSIS TOXIN; RECEPTOR BLOCKING AGENT; STROMAL CELL DERIVED FACTOR 1; T 140; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1 ANTIBODY; VERY LATE ACTIVATION ANTIGEN 4;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; BONE MARROW; CELL ADHESION; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG SMALL CELL CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROMA CELL;

ACTINS; ANIMALS; CARCINOMA, SMALL CELL; CELL ADHESION; CELL MOVEMENT; CHEMOKINES, CXC; EXTRACELLULAR MATRIX; HUMANS; INTEGRINS; LUNG NEOPLASMS; MICE; RECEPTORS, CXCR4; STROMAL CELLS;

ANIMALIA;

EID: 0345687920     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207097     Document Type: Article

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