메뉴 건너뛰기




Volumn 198, Issue 9, 2003, Pages 1391-1402

Regulation of the Chemokine Receptor CXCR4 by Hypoxia

Author keywords

Cell migration; Hypoxia inducible factor 1 (HIF 1); Low oxygen concentration; SDF 1 CXCL12 receptor (CXCR4)

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; STROMAL CELL DERIVED FACTOR 1;

EID: 10744219598     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030267     Document Type: Article
Times cited : (709)

References (55)
  • 1
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • Semenza, G.L. 2001. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol. Med. 7:345-350.
    • (2001) Trends Mol. Med. , vol.7 , pp. 345-350
    • Semenza, G.L.1
  • 2
    • 0033529656 scopus 로고    scopus 로고
    • Perspectives on oxygen sensing
    • Semenza, G.L. 1999. Perspectives on oxygen sensing. Cell. 98:281-284.
    • (1999) Cell , vol.98 , pp. 281-284
    • Semenza, G.L.1
  • 3
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang, G.L., B.H. Jiang, E.A. Rue, and G.L. Semenza. 1995. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. USA. 92:5510-5514.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 4
    • 0035101398 scopus 로고    scopus 로고
    • Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - A potential mechanism
    • Grimshaw, M.J., and F.R. Balkwill. 2001. Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - a potential mechanism. Eur. J. Immunol. 31:480-489.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 480-489
    • Grimshaw, M.J.1    Balkwill, F.R.2
  • 6
    • 0032499260 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Baggiolini, M. 1998. Chemokines and leukocyte traffic. Nature. 392:565-568.
    • (1998) Nature , vol.392 , pp. 565-568
    • Baggiolini, M.1
  • 7
  • 8
    • 0030825407 scopus 로고    scopus 로고
    • Chemokines
    • Rollins, B.J. 1997. Chemokines. Blood. 90:909-928.
    • (1997) Blood , vol.90 , pp. 909-928
    • Rollins, B.J.1
  • 9
    • 0036262275 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature
    • Murphy, P.M. 2002. International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature. Pharmacol. Rev. 54:227-229.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 227-229
    • Murphy, P.M.1
  • 12
    • 0035993208 scopus 로고    scopus 로고
    • Tumor-associated macrophages: A molecular perspective
    • Sica, A., A. Saccani, and A. Mantovani. 2002. Tumor-associated macrophages: a molecular perspective. Int. Immunopharmacol. 2:1045-1054.
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 1045-1054
    • Sica, A.1    Saccani, A.2    Mantovani, A.3
  • 13
    • 0033152142 scopus 로고    scopus 로고
    • The chemokine system: Redundancy for robust outputs
    • Mantovani, A. 1999. The chemokine system: redundancy for robust outputs. Immunol. Today. 20:254-257.
    • (1999) Immunol. Today , vol.20 , pp. 254-257
    • Mantovani, A.1
  • 15
    • 0029077772 scopus 로고
    • Hypoxia, oxidative stress and rheumatoid arthritis
    • Mapp, P.I., M.C. Grootveld, and D.R. Blake. 1995. Hypoxia, oxidative stress and rheumatoid arthritis. Br. Med. Bull. 51:419-436.
    • (1995) Br. Med. Bull. , vol.51 , pp. 419-436
    • Mapp, P.I.1    Grootveld, M.C.2    Blake, D.R.3
  • 16
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza, G.L. 2002. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 8:S62-S67.
    • (2002) Trends Mol. Med. , vol.8
    • Semenza, G.L.1
  • 18
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani, A., S. Sozzani, M. Locati, P. Allavena, and A. Sica. 2002. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23:549-555.
    • (2002) Trends Immunol. , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 19
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek, R.D., C.E. Lewis, R. Whitehouse, M. Greenall, J. Clarke, and A.L. Harris. 1996. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res. 56:4625-4629.
    • (1996) Cancer Res. , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 20
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration with angiogenesis and prognosis in invasive carcinoma of the breast
    • Leek, R.D., R.J. Landers, A.L. Harris, and C.E. Lewis. 1999. Necrosis correlates with high vascular density and focal macrophage infiltration with angiogenesis and prognosis in invasive carcinoma of the breast. Br. J. Cancer. 79:991-995.
    • (1999) Br. J. Cancer , vol.79 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 21
    • 0017674144 scopus 로고
    • Human mature macrophages mediate antybody-dependent cellular cytotoxicity on tumor cells
    • Mantovani, A., V. Caprioli, P. Gritti, and F. Spreafico. 1977. Human mature macrophages mediate antybody-dependent cellular cytotoxicity on tumor cells. Transplantation. 24:291-293.
    • (1977) Transplantation , vol.24 , pp. 291-293
    • Mantovani, A.1    Caprioli, V.2    Gritti, P.3    Spreafico, F.4
  • 23
    • 0032514685 scopus 로고    scopus 로고
    • Downregulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes
    • Ivanov, S.V., I. Kuzmin, M.H. Wei, S. Pack, L. Geil, B.E. Johnson, E.J. Stanbridge, and M.I. Lerman. 1998. Downregulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes. Proc. Natl. Acad. Sci. USA. 95:12596-12601.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12596-12601
    • Ivanov, S.V.1    Kuzmin, I.2    Wei, M.H.3    Pack, S.4    Geil, L.5    Johnson, B.E.6    Stanbridge, E.J.7    Lerman, M.I.8
  • 26
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo, G., T. Musso, A. Sica, L.S. Taylor, G.W. Cox, and L. Varesio. 1995. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. Exp. Med. 182:1683-1693.
    • (1995) J. Exp. Med. , vol.182 , pp. 1683-1693
    • Melillo, G.1    Musso, T.2    Sica, A.3    Taylor, L.S.4    Cox, G.W.5    Varesio, L.6
  • 28
    • 0032493368 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
    • Huang, E., J.M. Gu, M. Schau, and H.F. Bunn. 1998. Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA. 95:7987-7992.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7987-7992
    • Huang, E.1    Gu, J.M.2    Schau, M.3    Bunn, H.F.4
  • 29
    • 0036143654 scopus 로고    scopus 로고
    • p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment
    • Saccani, S., S. Pantano, and G. Natoli. 2002. p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat. Immmunol. 3:69-75.
    • (2002) Nat. Immmunol. , vol.3 , pp. 69-75
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 30
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
    • Wang, G.L., and G.L. Semenza. 1993. Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood. 82:3610-3615.
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 31
    • 0032948123 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha
    • Salcedo, R., K. Wasserman, H.A. Young, M.C. Grimm, O.M. Howard, M.R. Anver, H.K. Kleinman, W.J. Murphy, and J.J. Oppenheim. 1999. Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: in vivo neovascularization induced by stromal-derived factor-1alpha. Am. J. Pathol. 154:1125-1135.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1125-1135
    • Salcedo, R.1    Wasserman, K.2    Young, H.A.3    Grimm, M.C.4    Howard, O.M.5    Anver, M.R.6    Kleinman, H.K.7    Murphy, W.J.8    Oppenheim, J.J.9
  • 35
    • 0037035851 scopus 로고    scopus 로고
    • Structure of an HIF-1alpha-pVHL complex: Hydroxyproline recognition in signaling
    • Min, J.H., H. Yang, M. Ivan, F. Gertler, W.G. Jr. Kaelin, and N.P. Pavletich. 2002. Structure of an HIF-1alpha-pVHL complex: hydroxyproline recognition in signaling. Science. 296:1886-1889.
    • (2002) Science , vol.296 , pp. 1886-1889
    • Min, J.H.1    Yang, H.2    Ivan, M.3    Gertler, F.4    Kaelin W.G., Jr.5    Pavletich, N.P.6
  • 36
    • 0032211360 scopus 로고    scopus 로고
    • von Hippel-Lindau genemediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids
    • Lieubeau-Teillet, B., J. Rak, S. Jothy, O. Iliopoulos, W. Kaelin, and R.S. Kerbel. 1998. von Hippel-Lindau genemediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids. Cancer Res. 58:4957-4962.
    • (1998) Cancer Res. , vol.58 , pp. 4957-4962
    • Lieubeau-Teillet, B.1    Rak, J.2    Jothy, S.3    Iliopoulos, O.4    Kaelin, W.5    Kerbel, R.S.6
  • 37
    • 0030831655 scopus 로고    scopus 로고
    • Putative control of angiogenesis in hemangioblastomas by the von Hippel-Lindau tumor supressor gene
    • Stratman, R., M. Krieg, R. Haas, and K.H. Plate. 1997. Putative control of angiogenesis in hemangioblastomas by the von Hippel-Lindau tumor supressor gene. J. Neuropathol. Exp. Neurol. 56:1142-1152.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1142-1152
    • Stratman, R.1    Krieg, M.2    Haas, R.3    Plate, K.H.4
  • 39
    • 0036247665 scopus 로고    scopus 로고
    • The role of innate mediators in inflammatory response
    • Liew, F.Y., and I.B. McInnes. 2002. The role of innate mediators in inflammatory response. Mol. Immunol. 38:887-890.
    • (2002) Mol. Immunol. , vol.38 , pp. 887-890
    • Liew, F.Y.1    McInnes, I.B.2
  • 40
    • 0028362316 scopus 로고
    • The contribution of hypoxia-reperfusion injury to inflammatory synovitis: The influence of reactive oxygen intermediates on the transcriptional control of inflammation
    • Blake, D.R., P.G. Winyard, and R. Marok. 1994. The contribution of hypoxia-reperfusion injury to inflammatory synovitis: the influence of reactive oxygen intermediates on the transcriptional control of inflammation. Ann. NY Acad. Sci. 723:308-317.
    • (1994) Ann. NY Acad. Sci. , vol.723 , pp. 308-317
    • Blake, D.R.1    Winyard, P.G.2    Marok, R.3
  • 41
    • 0036225941 scopus 로고    scopus 로고
    • Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage
    • Cernanec, J., F. Guilak, J.B. Weinberg, D.S. Pisetsky, and B. Fermor. 2002. Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage. Arthritis Rheum. 46:968-975.
    • (2002) Arthritis Rheum. , vol.46 , pp. 968-975
    • Cernanec, J.1    Guilak, F.2    Weinberg, J.B.3    Pisetsky, D.S.4    Fermor, B.5
  • 42
    • 0035260881 scopus 로고    scopus 로고
    • Chemokines and disease
    • Gerard, C., and B.J. Rollins. 2001. Chemokines and disease. Nat. Immunol. 2:108-115.
    • (2001) Nat. Immunol. , vol.2 , pp. 108-115
    • Gerard, C.1    Rollins, B.J.2
  • 44
    • 0030781393 scopus 로고    scopus 로고
    • Multistep navigation and the combinatorial control of leukocyte chemotaxis
    • Foxman, E.F., J.J. Campbell, and E.C. Butcher. 1997. Multistep navigation and the combinatorial control of leukocyte chemotaxis. J. Cell Biol. 139:1349-1360.
    • (1997) J. Cell Biol. , vol.139 , pp. 1349-1360
    • Foxman, E.F.1    Campbell, J.J.2    Butcher, E.C.3
  • 45
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. 1995. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1:27-31.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 46
    • 0030576517 scopus 로고    scopus 로고
    • Patterns of emerging mechanisms of the angiogenic switch during tumongenesis
    • Hanahan, D., and J. Folkman. 1996. Patterns of emerging mechanisms of the angiogenic switch during tumongenesis. Cell. 86:353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 47
    • 0034787977 scopus 로고    scopus 로고
    • Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors
    • Crowther, M., N.J. Brown, E.T. Bishop, and C.E. Lewis. 2001. Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors. J. Leukoc. Biol. 70:478-490.
    • (2001) J. Leukoc. Biol. , vol.70 , pp. 478-490
    • Crowther, M.1    Brown, N.J.2    Bishop, E.T.3    Lewis, C.E.4
  • 48
    • 0035174962 scopus 로고    scopus 로고
    • The regulation of interleukin-8 by hypoxia in human macrophage - A potential role in the pathogenesis of the Acute Respiratory Distress Syndrome (ARDS)
    • Hirani, N., F. Antonicelli, R.M. Strieter, M.S. Wiesener, P.J. Ratcliffe, C. Haslett, and S.C. Donnelly. 2001. The regulation of interleukin-8 by hypoxia in human macrophage-a potential role in the pathogenesis of the Acute Respiratory Distress Syndrome (ARDS). Mol. Med. 10:685-697.
    • (2001) Mol. Med. , vol.10 , pp. 685-697
    • Hirani, N.1    Antonicelli, F.2    Strieter, R.M.3    Wiesener, M.S.4    Ratcliffe, P.J.5    Haslett, C.6    Donnelly, S.C.7
  • 49
    • 0036270898 scopus 로고    scopus 로고
    • The role of chemokines in melanoma tumor growth and metastasis
    • Payne, A.S., and L.A. Cornelius. 2002. The role of chemokines in melanoma tumor growth and metastasis. J. Invest. Dermatol. 118:915-922.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 915-922
    • Payne, A.S.1    Cornelius, L.A.2
  • 50
    • 0035686998 scopus 로고    scopus 로고
    • Role of chemokine SDF-1/PBSF and its receptor CXCR4 in blood vessel development
    • Nagasawa, T. 2001. Role of chemokine SDF-1/PBSF and its receptor CXCR4 in blood vessel development. Ann. NY Acad. Sci. 947:112-115.
    • (2001) Ann. NY Acad. Sci. , vol.947 , pp. 112-115
    • Nagasawa, T.1
  • 51
    • 0029363531 scopus 로고
    • The role of CXC chemokines as regulators of angiogenesis
    • Strieter, R.M., P.J. Polverini, D.A. Arenberg, and S.L. Kunkel. 1995. The role of CXC chemokines as regulators of angiogenesis. Shock. 4:155-160.
    • (1995) Shock , vol.4 , pp. 155-160
    • Strieter, R.M.1    Polverini, P.J.2    Arenberg, D.A.3    Kunkel, S.L.4
  • 52
    • 0035282610 scopus 로고    scopus 로고
    • An attractive force in metastasis
    • Liotta L.A. 2001. An attractive force in metastasis. Nature. 410:24-25.
    • (2001) Nature , vol.410 , pp. 24-25
    • Liotta, L.A.1
  • 53
    • 0031962524 scopus 로고    scopus 로고
    • The metastatic characteristics of murine lymphoma cell lines in vivo are manifested after target organ invasion
    • Aoudjit, F., E.F. Potworowski, and Y. St-Pierre. 1998. The metastatic characteristics of murine lymphoma cell lines in vivo are manifested after target organ invasion. Blood. 91:623-629.
    • (1998) Blood , vol.91 , pp. 623-629
    • Aoudjit, F.1    Potworowski, E.F.2    St-Pierre, Y.3
  • 55
    • 0037326037 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
    • Pugh, C.W., and P.J. Ratcliffe. 2003. The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Semin. Cancer Biol. 13:83-89.
    • (2003) Semin. Cancer Biol. , vol.13 , pp. 83-89
    • Pugh, C.W.1    Ratcliffe, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.