Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow

Leukemia

Volumn 18, Issue 1, 2004, Pages 29-40

  Ratajczak, M Z ^a,b   Kucia, M ^a,b   Reca, R ^a   Majka, M ^b   Janowska Wieczorek, A ^c   Ratajczak, J ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b JAGIELLONIAN UNIVERSITY   (Poland)

^c CANADIAN BLOOD SERVICES   (Canada)

Author keywords

CXCR4; SDF 1; Stem cell homing; Stem cell mobilization; Stem cell plasticity

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; FETOPROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; MESSENGER RNA; MYOD PROTEIN; MYOGENIC FACTOR 5; NESTIN; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; MOUSE; MUSCLE CELL; NERVE CELL; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; STEADY STATE; UPREGULATION;

EID: 0742306878     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403184     Document Type: Article

References (66)

1. Caplice NM, Bunch TJ, Stalboerger PG, Wang SW, Simpler D, Miller DV et al. Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation. Proc Natl Acad Sci USA 2003; 100: 4754-4759.
2. Qi H, Aguiar DJ, Williams SM, La Pean A, Pan W, Verfaillie CM. Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells. Proc Natl Acad Sci USA 2003; 100: 3305-3310.
3. Jiang Y, Jahagirdar BN, Reinhardt RL, Keene CD, Ortiz-Gonzalez XR, Reyes M et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
4. Orlic D, Kajstura J, Chimenti S, Bodine DM, Leri A, Anversa P. Bone marrow stem cells regenerate infarcted myocardium. Pediatr Transplant 2003; 7: 86-88.
5. Makino S, Fukuda K, Miyoshi S, Konishi F, Kodama H, Pan J et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999; 103: 697-705.
6. Labarge MA, Blau HM. Biological progression from adult bone marrow to mononucleate stem cells to multinucleate muscle fiber in response to injury. Cell 2002; 111: 589-601.
7. Corti S, Strazzer S, Del Bo R, Salani S, Bossolasco P, Fortunato F et al. A subpopulation of murine bone marrow cells fully differentiates along the myogenic pathway and participates in muscle repair in the mdx dystrophic mouse. Exp Cell Res 2002; 277: 74-85.
8. Sanchez-Ramos JR. Neural cells derived from adult bone marrow and umbilical cord blood. J Neurosci Res 2002; 69: 880-893.
9. Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N et al. Bone marrow as a potential source of hepatic oval cells. Science 1999; 284: 1168-1170.
10. Ianus A, Holz GG, Theise ND, Hussain MA. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest 2003; 111: 843-850.
11. Lee VM, Stoffel M. Bone marrow: an extra-pancreatic hideout for the elusive pancreatic stem cells? J Clin Invest 2003; 111: 799-801.
12. Korbling M, Katz RL, Khanna A, Ruifrok AC, Rondon G, Albitar M et al. Hepatocyte and epithelial cells of donor origin in recipients of peripheral-blood stem cells. N Engl J Med 2002; 346: 738-746.
13. Hao HN, Zhao J, Thomas RL, Parker GC, Lyman WD. Fetal human hematopoietic cells can differentiate sequentially into neural stem cells and then astrocytes in vitro. J Hematother Stem Cell Res 2003; 12: 23-32.
14. Stamm C, Westphal B, Kleine HD, Petzsch M, Kitter C, Klinge H et al. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 2003; 361: 45-46.
15. Lemischka IA. Few thoughts about the plasticity of stem cells. Exp Hematol 2002; 30: 848-852.
16. Holden C, Vogel G. Stem cells. Plasticity: time for a reappraisal? Science 2002; 296: 2126-2129.
17. Castro RF, Jackson KA, Goodell MA, Robertson CS, Liu H, Shine HD. Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science 2002; 297: 1299.
18. McKinney-Freeman SL, Jackson KA, Camargo FD, Ferrari G, Mavilio F, Goodell MA. Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci USA 2002; 99: 1341-1346.
19. Geiger H, True JM, Grimes B, Carroll EJ, Fleischman RA, Van Zant C. Analysis of the hematopoietic potential of muscle-derived cells in mice. Blood 2002; 100: 721-723.
20. Kawada H, Ogawa M. Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle. Blood 2001; 98: 2008-2013.
21. Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002; 297: 2256-2259.
22. Jackson KA, Mi T, Goodell MA. Hematopoietic potential of stem cells isolated from murine skeletal muscle. Proc Natl Acad Sci USA 1999; 96: 14482-14486.
23. Terada N, Hamazaki T, Oka OM, Hoki M, Mastalerz DM, Nakano Y et al. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002; 416: 542-454.
24. Ying QL, Nichols J, Evans EP, Smith AG. Changing potency by spontaneous fusion. Nature 2002; 416: 545-548.
25. Wang X, Willenbring H, Akkari Y, Toriaru Y, Foster M, Al-Dhalimy M et al. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature 2003; 422: 897-901.
26. Morshead CM, Benvenite P, Iscove NN, Van der Kooy D. Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med 2002; 8: 268-273.
27. Ogura A, Inoue K, Ogonuku N, Lee J, Kohda T, Ishino F. Phenotypic effects of somatic cell cloning in the mouse. Cloning Stem Cells 2002; 4: 397-405.
28. Jaenisch R, Eggan K, Humpherys D, Rideout W, Hochedlinger K. Nuclear cloning, stem cells, and genomic reprogramming. Cloning Stem Cells 2002; 4: 389-396.
29. Orkin SH, Zon LI. Hematopoiesis and stem cells; plasticity versus developmental heterogenity. Nat Immunol 2002; 3: 323-328.
30. Zou Y, Kottmann AH, Kuroda M, Taniuchi I, Littman DR. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998; 393: 595-599.
31. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001; 410: 50-56.
32. Cooper CR, Chay CH, Gendernalik JD, Lee HL, Bhatia J, Taichman RS et al. Stromal factors involved in prostate carcinoma metastasis to bone. Cancer 2003; 97: 739-747.
33. Ellis WJ, Pfitzenmaier J, Colli J, Arfman E, Lange PH, Vessella RL. Detection and isolation of prostate cancer cells from peripheral blood and bone marrow. Urology 2003; 61: 277-281.
34. Libura J, Drukala J, Majka M, Tomeascu O, Navenot JM, Kucia M et al. CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis and adhesion. Blood 2002; 100: 2597-2606.
35. Geminder H, Sagi-Assif O, Goldberg L, Meshel T, Rechavi G, Witz IP et al. A possible role for CXCR4 and its ligand the CXC chemokine stromal cell-derived factor-1 in the development of bone marrow metastasis in neuroblastoma. J Immunol 2001; 167: 4747-4757.
36. Lazarini F, Tham TN, Casanova P, Arenzana-Seisdedos F, Dubois-Dalcq M. Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia 2003; 42: 139-148.
37. Lu M, Grove EA, Miller RJ. Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc Natl Acad Sci USA 2002; 99: 7090-7095.
38. Pillarisetti K, Gupta SK. Cloning and relative expression analysis of rat stromal cell derived factor-1 (SDF-1): SDF-1 alpha mRNA is selectively induced in rat model of myocardial infarction. Inflammation 2001; 25: 293-300.
39. Ara T, Nakamura Y, Egawa T, Sugiyama T, Abe K, Kishimoto T et al. Impaired colonization of the gonads by primordial germ cells in mice lacking a chemokine stromal cell-derived factor-1 (SDF-1). Proc Natl Acad Sci USA 2003; 100: 5319-5323.
40. Doitsidou M, Reichman-Fried M, Stebler J, Köprunner M, Dörries J, Meyer D et al. Guidance of primordial germ cell migration by the chemokine SDF-1. Cell 2002; 111: 647-659.
41. Reiss K, Mentlein R, Sievers J, Hartmann D. Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer. Neuroscience 2002; 115: 295-305.
42. Crane IJ, Wallace CA, McKillop-Smith S, Forrester JV. CXCR4 receptor expression on human retinal pigment epithelial cells from blood-retina barrier leads to chemokine secretion and migration in response to stromal cell-derived factor 1α. J Immunol 2000; 165: 4372-4378.
43. Ratajczak MZ, Majka M, Kucia M, Drukala J, Pietrzkowski Z, Peiper S et al. Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles. Stem Cells 2003; 21: 363-371.
44. Pituch-Noworolska A, Majka M, Janowska-Wieczorek A, Baj-Krzyworzeka A, Urbanowicz B, Malec E et al. Circulating CXCR4-positive stem/progenitor cells compete for SDF-1-positive niches in bone marrow, muscle and neural tissues: an alternative hypothesis to stem cells plasticity. Folia Histochem Cytobiol 2003; 41: 13-21.
45. Hatch H, Zheng D, Jorgensen ML, Petersen BE. SDF-1α/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. Cloning Stem Cells 2002; 4: 339-351.
46. Bajetto A, Bonavia R, Barbero S, Piccioli P, Costa A, Florio T et al. Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1. J Neurochem 1999; 73: 2348-2357.
47. Majka M, Janowska-Wieczorek A, Ratajczak J, Kowalska MA, Vilaire G, Pan ZK et al. Stromal derived factor-1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis. Blood 2000; 96: 4142-4151.
48. Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K, Pietrzkowski Z, Kowalska MA et al. Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 2001; 97: 3075-3085.
49. Zhang W, Navenot JM, Haribabu B, Tamamura H, Hiramatu K, Omagari A et al. A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. J Biol Chem 2002; 277: 24515-24521.
50. Kijowski J, Baj M, Majka M, Reca R, Marquez LA, Christofidou-Solomidou M et al. The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. Stem Cells 2001; 19: 453-466.
51. Schwartz RE, Reyes M, Koodie L, Jiang Y, Blackstad M, Lund T et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002; 109: 1291-1302.
52. Vogel W, Grunebach F, Messam CA, Kanz L, Brugger W, Buhring HJ. Heterogeneity among human bone marrow-derived mesenchymal stem cells and neural progenitor cells. Haematologica 2003; 88: 126-133.
53. Jankowski RJ, Deasy BM, Cao B, Gates C, Huard J. The role of CD34 expression and cellular fusion in the regeneration capacity of myogenic progenitor cells. J Cell Sci 2002; 115: 4361-4374.
54. - hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 2000; 95: 2813-2820.
55. Corbeil D, Roper K, Hellwig A, Tavian M, Miraglia S, Watt SM et al. The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J Biol Chem 2000; 275: 5512-5520.
56. + stem cells restored dystrophin in mdx mice. J Cell Biol 2001; 152: 335-348.
57. Ito CY, Li CYJ, Bernstein A, Dick JF, Stanford WL. Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A null mice. Blood 2003; 101: 517-523.
58. Enver T, Heyworth CM, Dexter TM. Do stem cells play dice? Blood 1998; 92: 348-351.
59. Badorff C, Brandes RP, Popp R, Rupp S, Urbich C, Aicher A et al. Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes. Circulation 2003; 107: 1024-1032.
60. Spees JL, Olson SD, Ylostalo J, Lynch PJ, Smith J, Perry A et al. Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma. Proc Natl Acad Sci USA 2003; 100: 2397-2402.
61. Chesney J, Bacher M, Bender A, Bucala R. The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naïve T cells in situ. Proc Natl Acad Sci USA 1997; 94: 6307-6312.
62. Lin F, Cordes K, Li L, Hood L, Couser WG, Shankland SJ et al. Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 2003; 14: 1188-1199.
63. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 2001; 107: 1355-1356.
64. Asakura A, Seale P, Girgis-Gabardo A, Rudnicki MA. Myogenic specification of side population cells in skeletal muscle. J Cell Biol 2002; 159: 123-134.
65. Forbes SJ, Poulsom R, Wright NA. Hepatic and renal differentiation from blood-borne stem cells. Gene Ther 2002; 197: 419-423.
66. Weimann JM, Charlton CA, Brazelton TR, Hackman RC, Blau HM. Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains. Proc Natl Acad Sci USA 2003; 100: 2088-2093.