A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia

Journal of Biological Chemistry

Volumn 280, Issue 5, 2005, Pages 3493-3499

  Brusselmans, Koen ^a   Bono, Françoise ^b   Collen, Désiré ^a   Herbert, Jean Marc ^b   Carmeliet, Peter ^a   Dewerchin, Mieke ^a,c  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b SANOFI   (France)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ACTIVATION; ENZYME INHIBITION; GENES;

CELL APOPTOSIS; ENDOTHELIAL CELLS (EC); HYPOXIA; VASCULAR ENDOTHELIAL GROWTH FACTORS (VEGF);

CELLS;

BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; NEUROPILIN 1; PLACENTAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN; TRANSCRIPTION FACTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL SURVIVAL; EMBRYONIC STEM CELL; GENE DELETION; GENE INACTIVATION; GENE TARGETING; HYPOXIA; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

ANIMALS; ANOXIA; APOPTOSIS; AUTOCRINE COMMUNICATION; CELL SURVIVAL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MURIDAE; NEUROPILIN-1; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION FACTORS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

ANIMALIA;

EID: 13544251374     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406613200     Document Type: Article

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