Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

Journal of Clinical Investigation

Volumn 106, Issue 11, 2000, Pages 1331-1339

  Ponomaryov, Tanya ^a   Peled, Amnon ^a   Petit, Isabelle ^a   Taichman, Russell S ^b   Habler, Liliana ^c   Sandbank, Judith ^c   Arenzana Seisdedos, Fernando ^d   Magerus, Aude ^d   Caruz, Antonio ^e   Fujii, Nobutaka ^f   Nagler, Arnon ^g   Lahav, Meir ^h   Szyper Kravitz, Martin ^h   Zipori, Dov ^a   Lapidot, Tsvee ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^c ASSAF HAROFEH MEDICAL CENTER   (Israel)

^d INSTITUT PASTEUR   (France)

^e UNIVERSITY OF JAÉN   (Spain)

^f KYOTO UNIVERSITY   (Japan)

^g HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^h MEIR MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CYCLOPHOSPHAMIDE; DNA; FLUOROURACIL; GROWTH PROMOTOR; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL FUNCTION; CELL POPULATION; CONTROLLED STUDY; DNA DAMAGE; ENDOTHELIUM CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; IONIZING RADIATION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; STEM CELL;

EID: 0033647496     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI10329     Document Type: Article

References (64)

1. Stem cells: Units of development, units of regeneration, and units in evolution
2. Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4
3. 'Turning brain into blood': Clinical applications of stemcell research in neurobiology, and hematology
4. The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
5. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
6. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice
7. β2 microglobulin-deficient (β2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function
8. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mice using retroviral gene marking and cell purification: Implications for gene therapy
9. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
10. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoieric progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
11. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
12. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1
13. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
14. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
15. The chemokine receptor CXCR4 is required for the retention orb lineage and granulocytic precursors within the bone marrow microenvironment
16. A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconsritution
17. Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cyrokines: Possible role in progenitor survival
18. Recruitment of primitive peripheral blood cells: Synergism of interleukin 12 with interleukin 6 and stromal cell-derived factor-1
19. Enhanced myelopoiesis in SDF-1 transgenic mice: SDF-1 modulates myelopoiesis by regulating progenitor cell survival and inhibitory effects of myelosuppresive chemokines
20. Molecular cloning and structure of a pre-B-cell growth-stimulating factor
21. Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)
22. Activation of HIV-1 coreceptor (CXCR4) mediates myelosuppression
23. SDF-1 and TGF-β enhance the detection of transplantable human stern cells regenerating in NOD/SCID mice
24. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow
25. Selective secretion of chemoattractants for haemopoietic progenitor cells by bone marrow endothelial cells: A possible role in homing of haemopoietic progenitor ceils to bone marrow
26. The chemokine SDF-1 activates the integrins LFA-1, VLA-4 and VLA-5 on immature human CD34+ cells: Role in transendothelial/stromal migration and engraftment of NOD/SCID mice
27. SDF-1 induces survival, adhesion and migration in 3D ECM like gels of murine CXCR4 null fetal liver cells via another GPCR
28. Impairment of lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing SDF-1-intrakine
29. Self-renewal, differentiation or death: Regulation and manipulation of hematopoietic stem cell fate
30. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
31. Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma
32. Phenotypic heterogeneity among stromal cell lines from mouse bone marrow disclosed in their extracellular matrix composition and interactions with normal and leukemic cells
33. Cultured mouse marrow stromal cell lines. II. Distinct subtypes differing in morphologgy, collagen types, myelopoietic factors, and leukemic ceil growth modulating activities
34. Human bone cells in vitro
35. Human osteoblasts support hematopoiesis through the production of granulocyte colony-stimulating factor
36. Human osreoblast-like cells and osteosarcoma cell lines synthesize macrophage inhibitory protein 1alpha in response to interleukin 1beta and rumour necrosis factor alpha stimulation in vitro
37. Stromal cell-derived factor 1 (SDF-1) and antenatal human B cell lymphopoiesis: Expression of SDF-1 by mesothelial cells and biliary ductal plate epithelial cells
38. CXC chemokine receptor expression on human endothelial cells
39. A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
40. Predictive factors for peripheral-blood progenitor-cell collections using a single large-volume leukapheresis after cyclophosphamide and granulocyte-macrophage colony-stimulating factor mobilization
41. Circulating stem cells in mice treated with cydophosphamide
42. Functional isolation and characterization of human hematopoietic stem cells
43. Stem cell homing: Rolling, crawling, and nesting
44. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
45. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
46. A model of intramedullary hematopoietic microenvironments based on stereologic study of the distribution of endocloned marrow colonies
47. The architecture of bone marrow cell populations
48. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells
49. Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha
50. Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1
51. Selective transendothelial migration of hematopoietic progenitor cells: A role in homing of progenitor cells
52. Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin
53. Sublethal gamma irradiation increases IL-1alpha, IL-6, and TNF-alpha mRNA levels in murine hematopoietic tissues
54. Homing of fluorescently labeled routine hematopoietic stem cells
55. Optimal time interval between myeloablative whole body irradiation and reconstitution with syngeneic bone marrow graft
56. Disturbed CD4+ T cell homeostasis and in vitro HIV-1 susceptibility in transgenic mice expressing T cell line-tropic HIV-1 receptors
57. + stem cells to the spleen and bone marrow of immune deficient mice within 1-16 hours
58. CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells
59. Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers
60. The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1
61. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: A possible role for tumor progression
62. CXCR4 mRNA expression in colon, esophageal and gastric cancers and hepatitis C infected liver
63. Detection of breast cancer cells in the bone marrow or peripheral blood: Methods and prognostic significance
64. Establishment of human prostate carcinoma skeletal metastasis models