Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure

Cardiovascular Research

Volumn 47, Issue 4, 2000, Pages 778-787

  Damås, Jan K ^a,b   Eiken, Hans G ^a,b   Øie, Erik ^a   Bjerkeli, Vigdis ^b   Yndestad, Arne ^a,b   Ueland, Thor ^a,b   Tønnessen, Theis ^b   Geiran, Odd R ^a   Aass, Halfdan ^a   Simonsen, Svein ^a   Christensen, Geir ^b   Frøland, Stig S ^a,b   Attramadal, Håvard ^a   Gullestad, Lars ^a   Aukrust, Pål ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Cytokines; Gene expression; Heart failure; Infection inflammation; Monoclonal antibodies

Indexed keywords

ALPHA CHEMOKINE; BETA CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART FAILURE; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ANALYSIS OF VARIANCE; CARDIOMYOPATHY, DILATED; CASE-CONTROL STUDIES; CHEMOKINES, CC; CHEMOKINES, CXC; CORONARY DISEASE; FEMALE; GENE EXPRESSION; HEART FAILURE, CONGESTIVE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; MYOCARDIUM; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CXCR4; RECEPTORS, INTERLEUKIN-8A; RNA, MESSENGER;

EID: 18744424792     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00142-5     Document Type: Article

References (39)

1. Finkel M.S., Oddis C.V., Jacob T.D., et al. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science. 257:1992;387-389.
2. Yokoyama T., Vaca L., Rossen R.D., et al. Cellular basis for the negative inotropic effects of tumor necrosis factor-α in the mammalian heart. J Clin Invest. 92:1993;2303-2312.
3. Hirota H., Yoshida K., Kishimoto T., Taga T. Continuous activation of GP 130, a signal-transacting receptor component for interleukin-6 related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA. 92:1995;4862-4866.
4. Krown K.A., Page M.T., Nguyen C., et al. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. J Clin Invest. 98:1996;2854-2865.
5. Bozkurt B., Kribbs S.B., Clubb F.J. Jr., et al. Pathophysiologically relevant concentrations of tumor necrosis factor-α promote progressive left ventricular dysfunction and remodeling in rats. Circulation. 97:1998;1382-1391.
6. Taub D.D., Oppenheim J.J. Chemokines, inflammation and the immune system. Ther Immunol. 1:1994;229-246.
7. Bagglioni M., Dewald B., Moser B. Interleukin-8 and related chemotactic cytokines: CXC and CC-chemokines. Adv Immunol. 55:1994;97-179.
8. Jaeschke H., Smith C.W. Mechanisms of neutrophil-induced parenchymal cell injury. J Leukoc Biol. 61:1997;647-653.
9. i changes and respiratory burst in human neutrophils and monocytes induced by NAP-1/Interleukin-8, NAP-2 and gro/MGSA. J Leukoc Biol. 50:1991;279-286.
10. Boring L., Gosling J., Clearl M., Charo I.F. Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 394:1998;894-897.
11. Kolattukudy P.E., Quach T., Bergese S., et al. Myocarditis induced by targeted expression of the MCP-1 gene in murine cardiac muscle. Am J Pathol. 152:1998;101-111.
12. Kukielka G.L., Youker K.A., Michael L.H., et al. Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium. Mol Cell Biochem. 147:1995;5-12.
13. Aukrust P., Ueland T., Müller F., et al. Elevated circulating levels of C-C chemokines in patients with congestive heart failure. Circulation. 97:1998;1136-1143.
14. Damås J.K., Gullestad L., Ueland T., et al. CXC-chemokines, a new group of cytokines in congestive heart failure - possible role of platelets and monocytes. Cardiovasc Res. 45:2000;428-436.
15. Devaux B., Scholz D., Hirche A., Klovekorn W.P., Schaper J. Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure. Eur Heart J. 18:1997;470-479.
16. Luster A.D. Chemokines - chemotactic cytokines that mediate inflammation. N Engl J Med. 338:1998;436-445.
17. Nagasawa T., Hirota S., Tachibana K., et al. Defect of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 382:1996;635-638.
18. Chomezynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
19. Barnes D.A., Tse J., Kaufhold M., et al. Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model. J Clin Invest. 101:1998;2910-2919.
20. Lamkhioued B., Renzi P.M., Abi-Younes S. Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. J Immunol. 159:1997;4593-4601.
21. Z'Graggen K., Walz A., Mazzucchelli L., Strieter R.M., Mueller C. The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease. Gastroenterology. 113:1997;808-816.
22. Vonhof S., Brost B., Stille-Siegener M., et al. Monocyte activation in congestive heart failure due to coronary artery disease and idiopathic dilated cardiomyopathy. Int J Cardiol. 63:1998;237-244.
23. Rollins B.J., Walz A., Baggiolini M. Recombinant MCP-1/JE induces chemotaxis, calcium flux, and respiratory burst in human monocytes. Blood. 78:1991;1112-1116.
24. Buttke T.M., Sandstrom P.A. Oxidative stress as a mediator of apoptosis. Immunol Today. 15:1994;7-10.
25. Unemori E.N., Amento E.P., Bauer E.A., Horuk R. Melanoma growth-stimulatory activity/GRO decreases collagen expression by human fibroblasts. J Biol Chem. 268:1993;1338-1342.
26. Unemori E.N., Marsters J.C., Bauer E.A., Amento E.P. The product of the GRO gene regulates collagen turnover by inducing tissue inhibitor metalloproteinases. Arthritis Rheum. 34:1991;S117.
27. Koch A.E., Polverini P.J., Kunkel S.L., et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science. 258:1992;1798-1801.
28. Hesselgesser J., Taub D., Baskar P., et al. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4. Curr Biol. 8:1998;595-598.
29. Tachibana K., Hirota S., Ilizasa H., et al. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature. 393:1998;591-594.
30. Aukrust P., Gullestad L., Frøland S.S. Is apoptosis an important pathogenic factor in cardiovascular disease? Eur J Clin Invest. 29:1999;369-371.
31. + T cells. Proc Natl Acad Sci USA. 95:1998;12556-12561.
32. Herbein G., Mahlknecht U., Batliwalla F., et al. Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. Nature. 395:1998;189-194.
33. Lu Z., Berson J.F., Chen Y., et al. Evolution of HIV-1 co-receptor usage through interaction with distinct CCR5 and CXCR4 domains. Proc Natl Acad Sci USA. 94:1997;6426-6431.
34. Barbaro G., Di Lorenzo G., Grisorio B., Barbarini G. Incidence of dilated cardiomyopathy and detection of HIV in myocardial cells of HIV-positive patients. N Engl J Med. 339:1998;1093-1099.
35. Shioi T., Matsumori A., Kihara Y., et al. Increased expression of interleukin-1β and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in hypertrophied and failing heart with pressure overload. Circ Res. 81:1997;664-671.
36. Ono K., Matsumori A., Shioi T., Furukawa Y., Sasayama S. Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling. Circulation. 98:1998;149-156.
37. Freter R.R., Alberta J.A., Lam K.K., Stiles C.D. A new platelet-derived growth factor-regulated genomic element which binds serine/threonine phosphoprotein mediates induction of the slow immediately-early gene MCP-1. Mol Cell Biol. 15:1995;315-325.
38. Karakurum M., Shreeniwas R., Chen J., et al. Hypoxic induction of interleukin-8 gene expression in human endothelial cells. J Clin Invest. 93:1994;1564-1570.
39. Devalaraja M.N., Richmond A. Multiple chemotactic factors: fine control or redundancy? Trends Pharmacol Sci. 20:1999;151-156.