-
1
-
-
0038390128
-
Roles of cardiac transcription factors in cardiac hypertrophy
-
H. Akazawa, and I. Komuro Roles of cardiac transcription factors in cardiac hypertrophy Circ Res 92 2003 1079 1088
-
(2003)
Circ Res
, vol.92
, pp. 1079-1088
-
-
Akazawa, H.1
Komuro, I.2
-
2
-
-
0037348192
-
Too much Csx/Nkx2-5 is as bad as too little?
-
H. Akazawa, and I. Komuro Too much Csx/Nkx2-5 is as bad as too little? J Mol Cell Cardiol 35 2003 227 229
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 227-229
-
-
Akazawa, H.1
Komuro, I.2
-
3
-
-
0842288224
-
A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5
-
H. Akazawa, S. Kudoh, N. Mochizuki, N. Takekoshi, H. Takano, and T. Nagai A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5 J Cell Biol 164 2004 395 405
-
(2004)
J Cell Biol
, vol.164
, pp. 395-405
-
-
Akazawa, H.1
Kudoh, S.2
Mochizuki, N.3
Takekoshi, N.4
Takano, H.5
Nagai, T.6
-
4
-
-
0036333532
-
Regulation of avian cardiogenesis by Fgf8 signaling
-
B.H. Alsan, and T.M. Schultheiss Regulation of avian cardiogenesis by Fgf8 signaling Development 129 2002 1935 1943
-
(2002)
Development
, vol.129
, pp. 1935-1943
-
-
Alsan, B.H.1
Schultheiss, T.M.2
-
5
-
-
0033597114
-
Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site
-
B.A. Amendt, L.B. Sutherland, and A.F. Russo Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site J Biol Chem 274 1999 11635 11642
-
(1999)
J Biol Chem
, vol.274
, pp. 11635-11642
-
-
Amendt, B.A.1
Sutherland, L.B.2
Russo, A.F.3
-
7
-
-
0027237596
-
Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
-
N. Azpiazu, and M. Frasch tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila Genes Dev 7 1993 1325 1340
-
(1993)
Genes Dev
, vol.7
, pp. 1325-1340
-
-
Azpiazu, N.1
Frasch, M.2
-
8
-
-
0030636780
-
Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome
-
C.T. Basson, D.R. Bachinsky, R.C. Lin, T. Levi, J.A. Elkins, and J. Soults Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome Nat Genet 15 1997 30 35
-
(1997)
Nat Genet
, vol.15
, pp. 30-35
-
-
Basson, C.T.1
Bachinsky, D.R.2
Lin, R.C.3
Levi, T.4
Elkins, J.A.5
Soults, J.6
-
9
-
-
0033430230
-
Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
-
D.W. Benson, G.M. Silberbach, A. Kavanaugh-McHugh, C. Cottrill, Y. Zhang, and S. Riggs Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways J Clin Invest 104 1999 1567 1573
-
(1999)
J Clin Invest
, vol.104
, pp. 1567-1573
-
-
Benson, D.W.1
Silberbach, G.M.2
Kavanaugh-Mchugh, A.3
Cottrill, C.4
Zhang, Y.5
Riggs, S.6
-
10
-
-
0030926451
-
Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development
-
C. Biben, and R.P. Harvey Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development Genes Dev 11 1997 1357 1369
-
(1997)
Genes Dev
, vol.11
, pp. 1357-1369
-
-
Biben, C.1
Harvey, R.P.2
-
11
-
-
0031959594
-
Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart
-
C. Biben, T. Hatzistavrou, and R.P. Harvey Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart Mech Dev 73 1998 125 127
-
(1998)
Mech Dev
, vol.73
, pp. 125-127
-
-
Biben, C.1
Hatzistavrou, T.2
Harvey, R.P.3
-
12
-
-
0034634279
-
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5
-
C. Biben, R. Weber, S. Kesteven, E. Stanley, L. McDonald, and D.A. Elliott Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5 Circ Res 87 2000 888 895
-
(2000)
Circ Res
, vol.87
, pp. 888-895
-
-
Biben, C.1
Weber, R.2
Kesteven, S.3
Stanley, E.4
McDonald, L.5
Elliott, D.A.6
-
13
-
-
0027282774
-
The gene tinman is required for specification of the heart and visceral muscles in Drosophila
-
R. Bodmer The gene tinman is required for specification of the heart and visceral muscles in Drosophila Development 118 1993 719 729
-
(1993)
Development
, vol.118
, pp. 719-729
-
-
Bodmer, R.1
-
14
-
-
0025201511
-
A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila
-
R. Bodmer, L.Y. Jan, and Y.N. Jan A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila Development 110 1990 661 669
-
(1990)
Development
, vol.110
, pp. 661-669
-
-
Bodmer, R.1
Jan, L.Y.2
Jan, Y.N.3
-
15
-
-
0030746215
-
Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development
-
T. Brand, B. Andree, A. Schneider, A. Buchberger, and H.H. Arnold Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development Mech Dev 64 1997 53 59
-
(1997)
Mech Dev
, vol.64
, pp. 53-59
-
-
Brand, T.1
Andree, B.2
Schneider, A.3
Buchberger, A.4
Arnold, H.H.5
-
16
-
-
1642402120
-
The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer
-
C.O. Brown III, X. Chi, E. Garcia-Gras, M. Shirai, X.H. Feng, and R.J. Schwartz The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer J Biol Chem 279 2004 10659 10669
-
(2004)
J Biol Chem
, vol.279
, pp. 10659-10669
-
-
Brown III, C.O.1
Chi, X.2
Garcia-Gras, E.3
Shirai, M.4
Feng, X.H.5
Schwartz, R.J.6
-
17
-
-
0037155776
-
Transcriptional regulation of vertebrate cardiac morphogenesis
-
B.G. Bruneau Transcriptional regulation of vertebrate cardiac morphogenesis Circ Res 90 2002 509 519
-
(2002)
Circ Res
, vol.90
, pp. 509-519
-
-
Bruneau, B.G.1
-
18
-
-
0034650311
-
Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand
-
B.G. Bruneau, Z.Z. Bao, M. Tanaka, J.J. Schott, S. Izumo, and C.L. Cepko Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand Dev Biol 217 2000 266 277
-
(2000)
Dev Biol
, vol.217
, pp. 266-277
-
-
Bruneau, B.G.1
Bao, Z.Z.2
Tanaka, M.3
Schott, J.J.4
Izumo, S.5
Cepko, C.L.6
-
19
-
-
17944378083
-
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
B.G. Bruneau, G. Nemer, J.P. Schmitt, F. Charron, L. Robitaille, S. Caron, and D.A. Conner A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease Cell 106 2001 709 721
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.G.1
Nemer, G.2
Schmitt, J.P.3
Charron, F.4
Robitaille, L.5
Caron, S.6
Conner, D.A.7
-
20
-
-
0029984771
-
Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeobox gene tinman: Differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development
-
A. Buchberger, O. Pabst, T. Brand, K. Seidl, and H.H. Arnold Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeobox gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development Mech Dev 56 1996 151 163
-
(1996)
Mech Dev
, vol.56
, pp. 151-163
-
-
Buchberger, A.1
Pabst, O.2
Brand, T.3
Seidl, K.4
Arnold, H.H.5
-
21
-
-
20444448850
-
Myocardial-cell: The science, the clinic and the future
-
N.M. Caplice, and A. Deb Myocardial-cell: the science, the clinic and the future Nat Clinic Pract Cardiovasc Med 1 2004 90 95
-
(2004)
Nat Clinic Pract Cardiovasc Med
, vol.1
, pp. 90-95
-
-
Caplice, N.M.1
Deb, A.2
-
22
-
-
0030465318
-
Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation
-
J.N. Chen, and M.C. Fishman Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation Development 122 1996 3809 3816
-
(1996)
Development
, vol.122
, pp. 3809-3816
-
-
Chen, J.N.1
Fishman, M.C.2
-
23
-
-
0029046714
-
Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5
-
C.Y. Chen, and R.J. Schwartz Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5 J Biol Chem 270 1995 15628 15633
-
(1995)
J Biol Chem
, vol.270
, pp. 15628-15633
-
-
Chen, C.Y.1
Schwartz, R.J.2
-
24
-
-
0000634381
-
Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription
-
C.Y. Chen, and R.J. Schwartz Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription Mol Cell Biol 16 1996 6372 6384
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6372-6384
-
-
Chen, C.Y.1
Schwartz, R.J.2
-
25
-
-
18644374460
-
Hop is an unusual homeobox gene that modulates cardiac development
-
F. Chen, H. Kook, R. Milewski, A.D. Gitler, M.M. Lu, and J. Li Hop is an unusual homeobox gene that modulates cardiac development Cell 110 2002 713 723
-
(2002)
Cell
, vol.110
, pp. 713-723
-
-
Chen, F.1
Kook, H.2
Milewski, R.3
Gitler, A.D.4
Lu, M.M.5
Li, J.6
-
26
-
-
0029955134
-
Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia
-
O.B. Cleaver, K.D. Patterson, and P.A. Krieg Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia Development 122 1996 3549 3556
-
(1996)
Development
, vol.122
, pp. 3549-3556
-
-
Cleaver, O.B.1
Patterson, K.D.2
Krieg, P.A.3
-
27
-
-
0029779002
-
The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium
-
D. Durocher, C.Y. Chen, A. Ardati, R.J. Schwartz, and M. Nemer The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium Mol Cell Biol 16 1996 4648 4655
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4648-4655
-
-
Durocher, D.1
Chen, C.Y.2
Ardati, A.3
Schwartz, R.J.4
Nemer, M.5
-
28
-
-
0030799792
-
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
-
D. Durocher, F. Charron, R. Warren, R.J. Schwartz, and M. Nemer The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors EMBO J 16 1997 5687 5696
-
(1997)
EMBO J
, vol.16
, pp. 5687-5696
-
-
Durocher, D.1
Charron, F.2
Warren, R.3
Schwartz, R.J.4
Nemer, M.5
-
29
-
-
0032860232
-
WNT11 promotes cardiac tissue formation of early mesoderm
-
C.A. Eisenberg, and L.M. Eisenberg WNT11 promotes cardiac tissue formation of early mesoderm Dev Dyn 216 1999 45 58
-
(1999)
Dev Dyn
, vol.216
, pp. 45-58
-
-
Eisenberg, C.A.1
Eisenberg, L.M.2
-
30
-
-
0031057963
-
Wnt-11 is expressed in early avian mesoderm and required for the differentiation of the quail mesoderm cell line QCE-6
-
C.A. Eisenberg, R.G. Gourdie, and L.M. Eisenberg Wnt-11 is expressed in early avian mesoderm and required for the differentiation of the quail mesoderm cell line QCE-6 Development 124 1997 525 536
-
(1997)
Development
, vol.124
, pp. 525-536
-
-
Eisenberg, C.A.1
Gourdie, R.G.2
Eisenberg, L.M.3
-
31
-
-
0037975739
-
Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: Associations with atrial septal defect and hypoplastic left heart syndrome
-
D.A. Elliott, E.P. Kirk, T. Yeoh, S. Chandar, F. McKenzie, and P. Taylor Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: associations with atrial septal defect and hypoplastic left heart syndrome J Am Coll Cardiol 41 2003 2072 2076
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2072-2076
-
-
Elliott, D.A.1
Kirk, E.P.2
Yeoh, T.3
Chandar, S.4
McKenzie, F.5
Taylor, P.6
-
32
-
-
0028863326
-
Tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman
-
S.M. Evans, W. Yan, M.P. Murillo, J. Ponce, and N. Papalopulu tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman Development 121 1995 3889 3899
-
(1995)
Development
, vol.121
, pp. 3889-3899
-
-
Evans, S.M.1
Yan, W.2
Murillo, M.P.3
Ponce, J.4
Papalopulu, N.5
-
33
-
-
0031882143
-
Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
-
A.B. Firulli, D.G. McFadden, Q. Lin, D. Srivastava, and E.N. Olson Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1 Nat Genet 18 1998 266 270
-
(1998)
Nat Genet
, vol.18
, pp. 266-270
-
-
Firulli, A.B.1
McFadden, D.G.2
Lin, Q.3
Srivastava, D.4
Olson, E.N.5
-
34
-
-
0030664296
-
Parsing the heart: Genetic modules for organ assembly
-
M.C. Fishman, and E.N. Olson Parsing the heart: genetic modules for organ assembly Cell 91 1997 153 156
-
(1997)
Cell
, vol.91
, pp. 153-156
-
-
Fishman, M.C.1
Olson, E.N.2
-
35
-
-
0028903248
-
Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo
-
M. Frasch Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo Nature 374 1995 464 467
-
(1995)
Nature
, vol.374
, pp. 464-467
-
-
Frasch, M.1
-
36
-
-
0031647381
-
Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
-
Y. Fu, W. Yan, T.J. Mohun, and S.M. Evans Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner Development 125 1998 4439 4449
-
(1998)
Development
, vol.125
, pp. 4439-4449
-
-
Fu, Y.1
Yan, W.2
Mohun, T.J.3
Evans, S.M.4
-
37
-
-
0041703018
-
Endothelin-converting enzyme-1 (ECE-1) is a downstream target of the homeobox transcription factor Nkx2-5
-
H. Funke-Kaiser, J. Lemmer, C.V. Langsdorff, A. Thomas, S.D. Kovacevic, and M. Strasdat Endothelin-converting enzyme-1 (ECE-1) is a downstream target of the homeobox transcription factor Nkx2-5 FASEB J 17 2003 1487 1489
-
(2003)
FASEB J
, vol.17
, pp. 1487-1489
-
-
Funke-Kaiser, H.1
Lemmer, J.2
Langsdorff, C.V.3
Thomas, A.4
Kovacevic, S.D.5
Strasdat, M.6
-
38
-
-
0035923555
-
NKX2.5 mutations in patients with tetralogy of fallot
-
E. Goldmuntz, E. Geiger, and D.W. Benson NKX2.5 mutations in patients with tetralogy of fallot Circulation 104 2001 2565 2568
-
(2001)
Circulation
, vol.104
, pp. 2565-2568
-
-
Goldmuntz, E.1
Geiger, E.2
Benson, D.W.3
-
39
-
-
0032380010
-
Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5
-
M.W. Grow, and P.A. Krieg Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5 Dev Biol 204 1998 187 196
-
(1998)
Dev Biol
, vol.204
, pp. 187-196
-
-
Grow, M.W.1
Krieg, P.A.2
-
40
-
-
0035951807
-
COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development
-
L. Guo, J. Lynch, K. Nakamura, L. Fliegel, H. Kasahara, and S. Izumo COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development J Biol Chem 276 2001 2797 2801
-
(2001)
J Biol Chem
, vol.276
, pp. 2797-2801
-
-
Guo, L.1
Lynch, J.2
Nakamura, K.3
Fliegel, L.4
Kasahara, H.5
Izumo, S.6
-
41
-
-
0037093383
-
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: Implications for cardiac chamber formation
-
P.E. Habets, A.F. Moorman, D.E. Clout, M.A. van Roon, M. Lingbeek, and M. van Lohuizen Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation Genes Dev 16 2002 1234 1246
-
(2002)
Genes Dev
, vol.16
, pp. 1234-1246
-
-
Habets, P.E.1
Moorman, A.F.2
Clout, D.E.3
Van Roon, M.A.4
Lingbeek, M.5
Van Lohuizen, M.6
-
42
-
-
0030587603
-
NK-2 homeobox genes and heart development
-
R.P. Harvey NK-2 homeobox genes and heart development Dev Biol 178 1996 203 216
-
(1996)
Dev Biol
, vol.178
, pp. 203-216
-
-
Harvey, R.P.1
-
43
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
C.H. Heldin, K. Miyazono, and P. ten Dijke TGF-beta signalling from cell membrane to nucleus through SMAD proteins Nature 390 1997 465 471
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
44
-
-
0034931034
-
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
-
Y. Hiroi, S. Kudoh, K. Monzen, Y. Ikeda, Y. Yazaki, and R. Nagai Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation Nat Genet 28 2001 276 280
-
(2001)
Nat Genet
, vol.28
, pp. 276-280
-
-
Hiroi, Y.1
Kudoh, S.2
Monzen, K.3
Ikeda, Y.4
Yazaki, Y.5
Nagai, R.6
-
45
-
-
0033574574
-
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
-
H. Hirota, J. Chen, U.A. Betz, K. Rajewsky, Y. Gu, and J. Ross Jr. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress Cell 97 1999 189 198
-
(1999)
Cell
, vol.97
, pp. 189-198
-
-
Hirota, H.1
Chen, J.2
Betz, U.A.3
Rajewsky, K.4
Gu, Y.5
Ross Jr., J.6
-
46
-
-
0029737070
-
Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
-
B.L. Hogan Bone morphogenetic proteins: multifunctional regulators of vertebrate development Genes Dev 10 1996 1580 1594
-
(1996)
Genes Dev
, vol.10
, pp. 1580-1594
-
-
Hogan, B.L.1
-
47
-
-
0032975539
-
Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient
-
T. Hosoda, I. Komuro, I. Shiojima, Y. Hiroi, M. Harada, and Y. Murakawa Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient Jpn Circ J 63 1999 425 426
-
(1999)
Jpn Circ J
, vol.63
, pp. 425-426
-
-
Hosoda, T.1
Komuro, I.2
Shiojima, I.3
Hiroi, Y.4
Harada, M.5
Murakawa, Y.6
-
48
-
-
0036306830
-
Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease
-
Y. Ikeda, Y. Hiroi, T. Hosoda, T. Utsunomiya, S. Matsuo, and T. Ito Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease Circ J 66 2002 561 563
-
(2002)
Circ J
, vol.66
, pp. 561-563
-
-
Ikeda, Y.1
Hiroi, Y.2
Hosoda, T.3
Utsunomiya, T.4
Matsuo, S.5
Ito, T.6
-
51
-
-
11144355678
-
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system
-
P.Y. Jay, B.S. Harris, C.T. Maguire, A. Buerger, H. Wakimoto, and M. Tanaka Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system J Clin Invest 113 2004 1130 1137
-
(2004)
J Clin Invest
, vol.113
, pp. 1130-1137
-
-
Jay, P.Y.1
Harris, B.S.2
Maguire, C.T.3
Buerger, A.4
Wakimoto, H.5
Tanaka, M.6
-
52
-
-
8444240109
-
The LIM domain: From the cytoskeleton to the nucleus
-
J.L. Kadrmas, and M.C. Beckerle The LIM domain: from the cytoskeleton to the nucleus Nat Rev Mol Cell Biol 5 2004 920 931
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 920-931
-
-
Kadrmas, J.L.1
Beckerle, M.C.2
-
53
-
-
0032959891
-
Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tissue-specifying homeobox gene product Csx/Nkx2.5
-
H. Kasahara, and S. Izumo Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tissue-specifying homeobox gene product Csx/Nkx2.5 Mol Cell Biol 19 1999 526 536
-
(1999)
Mol Cell Biol
, vol.19
, pp. 526-536
-
-
Kasahara, H.1
Izumo, S.2
-
54
-
-
0032543267
-
Cardiac and extracardiac expression of Csx/Nkx2.5 homeodomain protein
-
H. Kasahara, S. Bartunkova, M. Schinke, M. Tanaka, and S. Izumo Cardiac and extracardiac expression of Csx/Nkx2.5 homeodomain protein Circ Res 82 1998 936 946
-
(1998)
Circ Res
, vol.82
, pp. 936-946
-
-
Kasahara, H.1
Bartunkova, S.2
Schinke, M.3
Tanaka, M.4
Izumo, S.5
-
55
-
-
0033912859
-
Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease
-
H. Kasahara, B. Lee, J.J. Schott, D.W. Benson, J.G. Seidman, and C.E. Seidman Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease J Clin Invest 106 2000 299 308
-
(2000)
J Clin Invest
, vol.106
, pp. 299-308
-
-
Kasahara, H.1
Lee, B.2
Schott, J.J.3
Benson, D.W.4
Seidman, J.G.5
Seidman, C.E.6
-
56
-
-
0035895925
-
Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein
-
H. Kasahara, A. Usheva, T. Ueyama, H. Aoki, N. Horikoshi, and S. Izumo Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein J Biol Chem 276 2001 4570 4580
-
(2001)
J Biol Chem
, vol.276
, pp. 4570-4580
-
-
Kasahara, H.1
Usheva, A.2
Ueyama, T.3
Aoki, H.4
Horikoshi, N.5
Izumo, S.6
-
57
-
-
0034947445
-
Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein
-
H. Kasahara, H. Wakimoto, M. Liu, C.T. Maguire, K.L. Converso, and T. Shioi Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein J Clin Invest 108 2001 189 201
-
(2001)
J Clin Invest
, vol.108
, pp. 189-201
-
-
Kasahara, H.1
Wakimoto, H.2
Liu, M.3
Maguire, C.T.4
Converso, K.L.5
Shioi, T.6
-
58
-
-
0037350193
-
Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes
-
H. Kasahara, T. Ueyama, H. Wakimoto, M.K. Liu, C.T. Maguire, and K.L. Converso Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes J Mol Cell Cardiol 35 2003 243 256
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 243-256
-
-
Kasahara, H.1
Ueyama, T.2
Wakimoto, H.3
Liu, M.K.4
Maguire, C.T.5
Converso, K.L.6
-
59
-
-
0036534107
-
The anterior heart-forming field: Voyage to the arterial pole of the heart
-
R.G. Kelly, and M.E. Buckingham The anterior heart-forming field: voyage to the arterial pole of the heart Trends Genet 18 2002 210 216
-
(2002)
Trends Genet
, vol.18
, pp. 210-216
-
-
Kelly, R.G.1
Buckingham, M.E.2
-
61
-
-
0032567957
-
Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
-
S. Kirchhoff, E. Nelles, A. Hagendorff, O. Kruger, O. Traub, and K. Willecke Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice Curr Biol 8 1998 299 302
-
(1998)
Curr Biol
, vol.8
, pp. 299-302
-
-
Kirchhoff, S.1
Nelles, E.2
Hagendorff, A.3
Kruger, O.4
Traub, O.5
Willecke, K.6
-
62
-
-
0027184211
-
Csx: A murine homeobox-containing gene specifically expressed in the developing heart
-
I. Komuro, and S. Izumo Csx: a murine homeobox-containing gene specifically expressed in the developing heart Proc Natl Acad Sci U S A 90 1993 8145 8149
-
(1993)
Proc Natl Acad Sci U S a
, vol.90
, pp. 8145-8149
-
-
Komuro, I.1
Izumo, S.2
-
63
-
-
0027460744
-
Control of cardiac gene expression by mechanical stress
-
I. Komuro, and Y. Yazaki Control of cardiac gene expression by mechanical stress Annu Rev Physiol 55 1993 55 75
-
(1993)
Annu Rev Physiol
, vol.55
, pp. 55-75
-
-
Komuro, I.1
Yazaki, Y.2
-
64
-
-
0030916211
-
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
-
C.T. Kuo, E.E. Morrisey, R. Anandappa, K. Sigrist, M.M. Lu, and M.S. Parmacek GATA4 transcription factor is required for ventral morphogenesis and heart tube formation Genes Dev 11 1997 1048 1060
-
(1997)
Genes Dev
, vol.11
, pp. 1048-1060
-
-
Kuo, C.T.1
Morrisey, E.E.2
Anandappa, R.3
Sigrist, K.4
Lu, M.M.5
Parmacek, M.S.6
-
65
-
-
0030589617
-
A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm
-
K.H. Lee, Q. Xu, and R.E. Breitbart A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm Dev Biol 180 1996 722 731
-
(1996)
Dev Biol
, vol.180
, pp. 722-731
-
-
Lee, K.H.1
Xu, Q.2
Breitbart, R.E.3
-
66
-
-
0031844382
-
The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
-
Y. Lee, T. Shioi, H. Kasahara, S.M. Jobe, R.J. Wiese, and B.E. Markham The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression Mol Cell Biol 18 1998 3120 3129
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3120-3129
-
-
Lee, Y.1
Shioi, T.2
Kasahara, H.3
Jobe, S.M.4
Wiese, R.J.5
Markham, B.E.6
-
67
-
-
7244255984
-
SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer
-
K.H. Lee, S. Evans, T.Y. Ruan, and A.B. Lassar SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer Development 131 2004 4709 4723
-
(2004)
Development
, vol.131
, pp. 4709-4723
-
-
Lee, K.H.1
Evans, S.2
Ruan, T.Y.3
Lassar, A.B.4
-
68
-
-
0025280867
-
Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
-
D. Levy, R.J. Garrison, D.D. Savage, W.B. Kannel, and W.P. Castelli Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study N Engl J Med 322 1990 1561 1566
-
(1990)
N Engl J Med
, vol.322
, pp. 1561-1566
-
-
Levy, D.1
Garrison, R.J.2
Savage, D.D.3
Kannel, W.B.4
Castelli, W.P.5
-
69
-
-
1842413728
-
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
-
Q.Y. Li, R.A. Newbury-Ecob, J.A. Terrett, D.I. Wilson, A.R. Curtis, and C.H. Yi Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family Nat Genet 15 1997 21 29
-
(1997)
Nat Genet
, vol.15
, pp. 21-29
-
-
Li, Q.Y.1
Newbury-Ecob, R.A.2
Terrett, J.A.3
Wilson, D.I.4
Curtis, A.R.5
Yi, C.H.6
-
70
-
-
0037091085
-
Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region
-
C.M. Liberatore, R.D. Searcy-Schrick, E.B. Vincent, and K.E. Yutzey Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region Dev Biol 244 2002 243 256
-
(2002)
Dev Biol
, vol.244
, pp. 243-256
-
-
Liberatore, C.M.1
Searcy-Schrick, R.D.2
Vincent, E.B.3
Yutzey, K.E.4
-
71
-
-
0032937224
-
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer
-
C.L. Lien, C. Wu, B. Mercer, R. Webb, J.A. Richardson, and E.N. Olson Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer Development 126 1999 75 84
-
(1999)
Development
, vol.126
, pp. 75-84
-
-
Lien, C.L.1
Wu, C.2
Mercer, B.3
Webb, R.4
Richardson, J.A.5
Olson, E.N.6
-
72
-
-
0037090906
-
Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site
-
C.L. Lien, J. McAnally, J.A. Richardson, and E.N. Olson Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site Dev Biol 244 2002 257 266
-
(2002)
Dev Biol
, vol.244
, pp. 257-266
-
-
Lien, C.L.1
McAnally, J.2
Richardson, J.A.3
Olson, E.N.4
-
73
-
-
0027383023
-
Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
-
T.J. Lints, L.M. Parsons, L. Hartley, I. Lyons, and R.P. Harvey Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants Development 119 1993 419 431
-
(1993)
Development
, vol.119
, pp. 419-431
-
-
Lints, T.J.1
Parsons, L.M.2
Hartley, L.3
Lyons, I.4
Harvey, R.P.5
-
74
-
-
0034713820
-
Left ventricular hypertrophy: Pathogenesis, detection, and prognosis
-
B.H. Lorell, and B.A. Carabello Left ventricular hypertrophy: pathogenesis, detection, and prognosis Circulation 102 2000 470 479
-
(2000)
Circulation
, vol.102
, pp. 470-479
-
-
Lorell, B.H.1
Carabello, B.A.2
-
75
-
-
0029090829
-
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
-
I. Lyons, L.M. Parsons, L. Hartley, R. Li, J.E. Andrews, and L. Robb Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5 Genes Dev 9 1995 1654 1666
-
(1995)
Genes Dev
, vol.9
, pp. 1654-1666
-
-
Lyons, I.1
Parsons, L.M.2
Hartley, L.3
Li, R.4
Andrews, J.E.5
Robb, L.6
-
76
-
-
0035252357
-
Inhibition of Wnt activity induces heart formation from posterior mesoderm
-
M.J. Marvin, G. Di Rocco, A. Gardiner, S.M. Bush, and A.B. Lassar Inhibition of Wnt activity induces heart formation from posterior mesoderm Genes Dev 15 2001 316 327
-
(2001)
Genes Dev
, vol.15
, pp. 316-327
-
-
Marvin, M.J.1
Di Rocco, G.2
Gardiner, A.3
Bush, S.M.4
Lassar, A.B.5
-
77
-
-
3142554538
-
Stem cells and repair of the heart
-
A. Mathur, and J.F. Martin Stem cells and repair of the heart Lancet 364 2004 183 192
-
(2004)
Lancet
, vol.364
, pp. 183-192
-
-
Mathur, A.1
Martin, J.F.2
-
78
-
-
12144287908
-
Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes
-
K. Matsuura, T. Nagai, N. Nishigaki, T. Oyama, J. Nishi, and H. Wada Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes J Biol Chem 279 2004 11384 11391
-
(2004)
J Biol Chem
, vol.279
, pp. 11384-11391
-
-
Matsuura, K.1
Nagai, T.2
Nishigaki, N.3
Oyama, T.4
Nishi, J.5
Wada, H.6
-
79
-
-
0242636701
-
NKX2.5 mutations in patients with congenital heart disease
-
D.B. McElhinney, E. Geiger, J. Blinder, D. Woodrow Benson, and E. Goldmuntz NKX2.5 mutations in patients with congenital heart disease J Am Coll Cardiol 42 2003 1650 1655
-
(2003)
J Am Coll Cardiol
, vol.42
, pp. 1650-1655
-
-
McElhinney, D.B.1
Geiger, E.2
Blinder, J.3
Woodrow Benson, D.4
Goldmuntz, E.5
-
80
-
-
0029740603
-
BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein mix 1
-
P.E. Mead, I.H. Brivanlou, C.M. Kelley, and L.I. Zon BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein mix 1 Nature 382 1996 357 360
-
(1996)
Nature
, vol.382
, pp. 357-360
-
-
Mead, P.E.1
Brivanlou, I.H.2
Kelley, C.M.3
Zon, L.I.4
-
81
-
-
0034671733
-
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression
-
J.D. Molkentin The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression J Biol Chem 275 2000 38949 38952
-
(2000)
J Biol Chem
, vol.275
, pp. 38949-38952
-
-
Molkentin, J.D.1
-
82
-
-
0032850596
-
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4
-
K. Monzen, I. Shiojima, Y. Hiroi, S. Kudoh, T. Oka, and E. Takimoto Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4 Mol Cell Biol 19 1999 7096 7105
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7096-7105
-
-
Monzen, K.1
Shiojima, I.2
Hiroi, Y.3
Kudoh, S.4
Oka, T.5
Takimoto, E.6
-
83
-
-
0035858884
-
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation
-
K. Monzen, Y. Hiroi, S. Kudoh, H. Akazawa, T. Oka, and E. Takimoto Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation J Cell Biol 153 2001 687 698
-
(2001)
J Cell Biol
, vol.153
, pp. 687-698
-
-
Monzen, K.1
Hiroi, Y.2
Kudoh, S.3
Akazawa, H.4
Oka, T.5
Takimoto, E.6
-
84
-
-
18744395182
-
Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes
-
K. Monzen, W. Zhu, H. Kasai, Y. Hiroi, T. Hosoda, and H. Akazawa Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes Biochem Biophys Res Commun 298 2002 493 500
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 493-500
-
-
Monzen, K.1
Zhu, W.2
Kasai, H.3
Hiroi, Y.4
Hosoda, T.5
Akazawa, H.6
-
85
-
-
0036660872
-
Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor
-
J.G. Muller, J.T. Thompson, A.M. Edmonson, M.S. Rackley, H. Kasahara, and S. Izumo Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor J Mol Cell Cardiol 34 2002 807 821
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 807-821
-
-
Muller, J.G.1
Thompson, J.T.2
Edmonson, A.M.3
Rackley, M.S.4
Kasahara, H.5
Izumo, S.6
-
86
-
-
0242270619
-
Early stage-specific inhibitions of cardiomyocyte differentiation and expression of Csx/Nkx-2.5 and GATA-4 by phosphatidylinositol 3-kinase inhibitor LY294002
-
A.T. Naito, A. Tominaga, M. Oyamada, Y. Oyamada, I. Shiraishi, and K. Monzen Early stage-specific inhibitions of cardiomyocyte differentiation and expression of Csx/Nkx-2.5 and GATA-4 by phosphatidylinositol 3-kinase inhibitor LY294002 Exp Cell Res 291 2003 56 69
-
(2003)
Exp Cell Res
, vol.291
, pp. 56-69
-
-
Naito, A.T.1
Tominaga, A.2
Oyamada, M.3
Oyamada, Y.4
Shiraishi, I.5
Monzen, K.6
-
88
-
-
0031835362
-
Tinman-related genes expressed during heart development in Xenopus
-
C.S. Newman, and P.A. Krieg Tinman-related genes expressed during heart development in Xenopus Dev Genet 22 1998 230 238
-
(1998)
Dev Genet
, vol.22
, pp. 230-238
-
-
Newman, C.S.1
Krieg, P.A.2
-
89
-
-
0033994198
-
Transient cardiac expression of the tinman-family homeobox gene, XNkx2-10
-
C.S. Newman, J. Reecy, M.W. Grow, K. Ni, T. Boettger, and M. Kessel Transient cardiac expression of the tinman-family homeobox gene, XNkx2-10 Mech Dev 91 2000 369 373
-
(2000)
Mech Dev
, vol.91
, pp. 369-373
-
-
Newman, C.S.1
Reecy, J.2
Grow, M.W.3
Ni, K.4
Boettger, T.5
Kessel, M.6
-
90
-
-
0142027772
-
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
-
H. Oh, S.B. Bradfute, T.D. Gallardo, T. Nakamura, V. Gaussin, and Y. Mishina Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction Proc Natl Acad Sci U S A 100 2003 12313 12318
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 12313-12318
-
-
Oh, H.1
Bradfute, S.B.2
Gallardo, T.D.3
Nakamura, T.4
Gaussin, V.5
Mishina, Y.6
-
91
-
-
0030043669
-
Molecular pathways controlling heart development
-
E.N. Olson, and D. Srivastava Molecular pathways controlling heart development Science 272 1996 671 676
-
(1996)
Science
, vol.272
, pp. 671-676
-
-
Olson, E.N.1
Srivastava, D.2
-
92
-
-
0031812546
-
Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm
-
D. Onichtchouk, A. Glinka, and C. Niehrs Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm Development 125 1998 1447 1456
-
(1998)
Development
, vol.125
, pp. 1447-1456
-
-
Onichtchouk, D.1
Glinka, A.2
Niehrs, C.3
-
93
-
-
0037043688
-
Wnt-11 activation of a noncanonical Wnt signalling pathway is required for cardiogenesis
-
P. Pandur, M. Lasche, L.M. Eisenberg, and M. Kuhl Wnt-11 activation of a noncanonical Wnt signalling pathway is required for cardiogenesis Nature 418 2002 636 641
-
(2002)
Nature
, vol.418
, pp. 636-641
-
-
Pandur, P.1
Lasche, M.2
Eisenberg, L.M.3
Kuhl, M.4
-
94
-
-
0037047155
-
Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes
-
J. Paquin, B.A. Danalache, M. Jankowski, S.M. McCann, and J. Gutkowska Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes Proc Natl Acad Sci U S A 99 2002 9550 9555
-
(2002)
Proc Natl Acad Sci U S a
, vol.99
, pp. 9550-9555
-
-
Paquin, J.1
Danalache, B.A.2
Jankowski, M.3
McCann, S.M.4
Gutkowska, J.5
-
95
-
-
0030578428
-
The wingless signaling pathway is directly involved in Drosophila heart development
-
M. Park, X. Wu, K. Golden, J.D. Axelrod, and R. Bodmer The wingless signaling pathway is directly involved in Drosophila heart development Dev Biol 177 1996 104 116
-
(1996)
Dev Biol
, vol.177
, pp. 104-116
-
-
Park, M.1
Wu, X.2
Golden, K.3
Axelrod, J.D.4
Bodmer, R.5
-
96
-
-
13144257684
-
Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes
-
M. Park, C. Lewis, D. Turbay, A. Chung, J.N. Chen, and S. Evans Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes Proc Natl Acad Sci U S A 95 1998 9366 9371
-
(1998)
Proc Natl Acad Sci U S a
, vol.95
, pp. 9366-9371
-
-
Park, M.1
Lewis, C.2
Turbay, D.3
Chung, A.4
Chen, J.N.5
Evans, S.6
-
97
-
-
0031833737
-
Dual role for the zeste-white3/shaggyencoded kinase in mesoderm and heart development of Drosophila
-
M. Park, T.V. Venkatesh, and R. Bodmer Dual role for the zeste-white3/shaggyencoded kinase in mesoderm and heart development of Drosophila Dev Genet 22 1998 201 211
-
(1998)
Dev Genet
, vol.22
, pp. 201-211
-
-
Park, M.1
Venkatesh, T.V.2
Bodmer, R.3
-
98
-
-
11144357335
-
Nkx2-5 pathways and congenital heart disease; Loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block
-
M. Pashmforoush, J.T. Lu, H. Chen, T.S. Amand, R. Kondo, and S. Pradervand Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block Cell 117 2004 373 386
-
(2004)
Cell
, vol.117
, pp. 373-386
-
-
Pashmforoush, M.1
Lu, J.T.2
Chen, H.3
Amand, T.S.4
Kondo, R.5
Pradervand, S.6
-
99
-
-
0042466555
-
GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation
-
T. Peterkin, A. Gibson, and R. Patient GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation EMBO J 22 2003 4260 4273
-
(2003)
EMBO J
, vol.22
, pp. 4260-4273
-
-
Peterkin, T.1
Gibson, A.2
Patient, R.3
-
100
-
-
0031685432
-
Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice
-
G. Ranganayakulu, D.A. Elliott, R.P. Harvey, and E.N. Olson Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice Development 125 1998 3037 3048
-
(1998)
Development
, vol.125
, pp. 3037-3048
-
-
Ranganayakulu, G.1
Elliott, D.A.2
Harvey, R.P.3
Olson, E.N.4
-
101
-
-
4444298928
-
Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease
-
S.M. Reamon-Buettner, and J. Borlak Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease J Med Genet 41 2004 684 690
-
(2004)
J Med Genet
, vol.41
, pp. 684-690
-
-
Reamon-Buettner, S.M.1
Borlak, J.2
-
102
-
-
2442705544
-
Novel NKX2-5 mutations in diseased heart tissues of patients with cardiac malformations
-
S.M. Reamon-Buettner, H. Hecker, K. Spanel-Borowski, S. Craatz, E. Kuenzel, and J. Borlak Novel NKX2-5 mutations in diseased heart tissues of patients with cardiac malformations Am J Pathol 164 2004 2117 2125
-
(2004)
Am J Pathol
, vol.164
, pp. 2117-2125
-
-
Reamon-Buettner, S.M.1
Hecker, H.2
Spanel-Borowski, K.3
Craatz, S.4
Kuenzel, E.5
Borlak, J.6
-
103
-
-
0031571635
-
Chicken Nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm
-
J.M. Reecy, M. Yamada, K. Cummings, D. Sosic, C.Y. Chen, and G. Eichele Chicken Nkx-2.8: a novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm Dev Biol 188 1997 295 311
-
(1997)
Dev Biol
, vol.188
, pp. 295-311
-
-
Reecy, J.M.1
Yamada, M.2
Cummings, K.3
Sosic, D.4
Chen, C.Y.5
Eichele, G.6
-
104
-
-
0033013018
-
Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5
-
J.M. Reecy, X. Li, M. Yamada, F.J. DeMayo, C.S. Newman, and R.P. Harvey Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5 Development 126 1999 839 849
-
(1999)
Development
, vol.126
, pp. 839-849
-
-
Reecy, J.M.1
Li, X.2
Yamada, M.3
Demayo, F.J.4
Newman, C.S.5
Harvey, R.P.6
-
105
-
-
0031882249
-
The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
-
P. Riley, L. Anson-Cartwright, and J.C. Cross The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis Nat Genet 18 1998 271 275
-
(1998)
Nat Genet
, vol.18
, pp. 271-275
-
-
Riley, P.1
Anson-Cartwright, L.2
Cross, J.C.3
-
106
-
-
0034329539
-
Early exclusion of hand1-deficient cells from distinct regions of the left ventricular myocardium in chimeric mouse embryos
-
P.R. Riley, M. Gertsenstein, K. Dawson, and J.C. Cross Early exclusion of hand1-deficient cells from distinct regions of the left ventricular myocardium in chimeric mouse embryos Dev Biol 227 2000 156 168
-
(2000)
Dev Biol
, vol.227
, pp. 156-168
-
-
Riley, P.R.1
Gertsenstein, M.2
Dawson, K.3
Cross, J.C.4
-
107
-
-
0033553573
-
Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5
-
S.A. Rivkees, M. Chen, J. Kulkarni, J. Browne, and Z. Zhao Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5 J Biol Chem 274 1999 14204 14209
-
(1999)
J Biol Chem
, vol.274
, pp. 14204-14209
-
-
Rivkees, S.A.1
Chen, M.2
Kulkarni, J.3
Browne, J.4
Zhao, Z.5
-
108
-
-
0032809986
-
Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice
-
N. Saadane, L. Alpert, and L.E. Chalifour Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice Br J Pharmacol 127 1999 1165 1176
-
(1999)
Br J Pharmacol
, vol.127
, pp. 1165-1176
-
-
Saadane, N.1
Alpert, L.2
Chalifour, L.E.3
-
109
-
-
0030969371
-
The cellular and molecular response of cardiac myocytes to mechanical stress
-
J. Sadoshima, and S. Izumo The cellular and molecular response of cardiac myocytes to mechanical stress Annu Rev Physiol 59 1997 551 571
-
(1997)
Annu Rev Physiol
, vol.59
, pp. 551-571
-
-
Sadoshima, J.1
Izumo, S.2
-
110
-
-
0035252543
-
Wnt antagonism initiates cardiogenesis in Xenopus laevis
-
V.A. Schneider, and M. Mercola Wnt antagonism initiates cardiogenesis in Xenopus laevis Genes Dev 15 2001 304 315
-
(2001)
Genes Dev
, vol.15
, pp. 304-315
-
-
Schneider, V.A.1
Mercola, M.2
-
111
-
-
0032479573
-
Congenital heart disease caused by mutations in the transcription factor NKX2-5
-
J.J. Schott, D.W. Benson, C.T. Basson, W. Pease, G.M. Silberbach, and J.P. Moak Congenital heart disease caused by mutations in the transcription factor NKX2-5 Science 281 1998 108 111
-
(1998)
Science
, vol.281
, pp. 108-111
-
-
Schott, J.J.1
Benson, D.W.2
Basson, C.T.3
Pease, W.4
Silberbach, G.M.5
Moak, J.P.6
-
112
-
-
0029583152
-
Induction of avian cardiac myogenesis by anterior endoderm
-
T.M. Schultheiss, S. Xydas, and A.B. Lassar Induction of avian cardiac myogenesis by anterior endoderm Development 121 1995 4203 4214
-
(1995)
Development
, vol.121
, pp. 4203-4214
-
-
Schultheiss, T.M.1
Xydas, S.2
Lassar, A.B.3
-
113
-
-
0031018002
-
A role for bone morphogenetic proteins in the induction of cardiac myogenesis
-
T.M. Schultheiss, J.B. Burch, and A.B. Lassar A role for bone morphogenetic proteins in the induction of cardiac myogenesis Genes Dev 11 1997 451 462
-
(1997)
Genes Dev
, vol.11
, pp. 451-462
-
-
Schultheiss, T.M.1
Burch, J.B.2
Lassar, A.B.3
-
114
-
-
0032727374
-
Building the heart piece by piece: Modularity of cis-elements regulating Nkx2-5 transcription
-
R.J. Schwartz, and E.N. Olson Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription Development 126 1999 4187 4192
-
(1999)
Development
, vol.126
, pp. 4187-4192
-
-
Schwartz, R.J.1
Olson, E.N.2
-
115
-
-
0031647382
-
A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice
-
R.D. Searcy, E.B. Vincent, C.M. Liberatore, and K.E. Yutzey A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice Development 125 1998 4461 4470
-
(1998)
Development
, vol.125
, pp. 4461-4470
-
-
Searcy, R.D.1
Vincent, E.B.2
Liberatore, C.M.3
Yutzey, K.E.4
-
116
-
-
0031815073
-
GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: Role for regulating early cardiac gene expression
-
J.L. Sepulveda, N. Belaguli, V. Nigam, C.Y. Chen, M. Nemer, and R.J. Schwartz GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression Mol Cell Biol 18 1998 3405 3415
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3405-3415
-
-
Sepulveda, J.L.1
Belaguli, N.2
Nigam, V.3
Chen, C.Y.4
Nemer, M.5
Schwartz, R.J.6
-
117
-
-
0034663217
-
BMP signaling is required for heart formation in vertebrates
-
Y. Shi, S. Katsev, C. Cai, and S. Evans BMP signaling is required for heart formation in vertebrates Dev Biol 224 2000 226 237
-
(2000)
Dev Biol
, vol.224
, pp. 226-237
-
-
Shi, Y.1
Katsev, S.2
Cai, C.3
Evans, S.4
-
118
-
-
18644364557
-
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein
-
C.H. Shin, Z.P. Liu, R. Passier, C.L. Zhang, D.Z. Wang, and T.M. Harris Modulation of cardiac growth and development by HOP, an unusual homeodomain protein Cell 110 2002 725 735
-
(2002)
Cell
, vol.110
, pp. 725-735
-
-
Shin, C.H.1
Liu, Z.P.2
Passier, R.3
Zhang, C.L.4
Wang, D.Z.5
Harris, T.M.6
-
119
-
-
0029027507
-
Assignment of cardiac homeobox gene CSX to human chromosome 5q34
-
I. Shiojima, I. Komuro, J. Inazawa, Y. Nakahori, I. Matsushita, and T. Abe Assignment of cardiac homeobox gene CSX to human chromosome 5q34 Genomics 27 1995 204 206
-
(1995)
Genomics
, vol.27
, pp. 204-206
-
-
Shiojima, I.1
Komuro, I.2
Inazawa, J.3
Nakahori, Y.4
Matsushita, I.5
Abe, T.6
-
120
-
-
0029972345
-
Molecular cloning and characterization of human cardiac homeobox gene CSX1
-
I. Shiojima, I. Komuro, T. Mizuno, R. Aikawa, H. Akazawa, and T. Oka Molecular cloning and characterization of human cardiac homeobox gene CSX1 Circ Res 79 1996 920 929
-
(1996)
Circ Res
, vol.79
, pp. 920-929
-
-
Shiojima, I.1
Komuro, I.2
Mizuno, T.3
Aikawa, R.4
Akazawa, H.5
Oka, T.6
-
121
-
-
0033583178
-
Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx- 2.5 and GATA-4
-
I. Shiojima, I. Komuro, T. Oka, Y. Hiroi, T. Mizuno, and E. Takimoto Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx- 2.5 and GATA-4 J Biol Chem 274 1999 8231 8239
-
(1999)
J Biol Chem
, vol.274
, pp. 8231-8239
-
-
Shiojima, I.1
Komuro, I.2
Oka, T.3
Hiroi, Y.4
Mizuno, T.5
Takimoto, E.6
-
122
-
-
0034674286
-
Transcriptional regulation of human cardiac homeobox gene CSX1
-
I. Shiojima, T. Oka, Y. Hiroi, R. Nagai, Y. Yazaki, and I. Komuro Transcriptional regulation of human cardiac homeobox gene CSX1 Biochem Biophys Res Commun 272 2000 749 757
-
(2000)
Biochem Biophys Res Commun
, vol.272
, pp. 749-757
-
-
Shiojima, I.1
Oka, T.2
Hiroi, Y.3
Nagai, R.4
Yazaki, Y.5
Komuro, I.6
-
123
-
-
0036073842
-
The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis
-
M. Shirai, T. Osugi, H. Koga, Y. Kaji, E. Takimoto, and I. Komuro The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis J Clin Invest 110 2002 177 184
-
(2002)
J Clin Invest
, vol.110
, pp. 177-184
-
-
Shirai, M.1
Osugi, T.2
Koga, H.3
Kaji, Y.4
Takimoto, E.5
Komuro, I.6
-
124
-
-
17744364498
-
Two-step regulation of left-right asymmetric expression of Pitx2: Initiation by nodal signaling and maintenance by Nkx2
-
H. Shiratori, R. Sakuma, M. Watanabe, H. Hashiguchi, K. Mochida, and Y. Sakai Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2 Mol Cell 7 2001 137 149
-
(2001)
Mol Cell
, vol.7
, pp. 137-149
-
-
Shiratori, H.1
Sakuma, R.2
Watanabe, M.3
Hashiguchi, H.4
Mochida, K.5
Sakai, Y.6
-
125
-
-
0032567887
-
Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
-
A.M. Simon, D.A. Goodenough, and D.L. Paul Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block Curr Biol 8 1998 295 298
-
(1998)
Curr Biol
, vol.8
, pp. 295-298
-
-
Simon, A.M.1
Goodenough, D.A.2
Paul, D.L.3
-
126
-
-
0033119649
-
T-box genes: What they do and how they do it
-
J. Smith T-box genes: what they do and how they do it Trends Genet 15 1999 154 158
-
(1999)
Trends Genet
, vol.15
, pp. 154-158
-
-
Smith, J.1
-
127
-
-
0033000465
-
HAND proteins: Molecular mediators of cardiac development and congenital heart disease
-
D. Srivastava HAND proteins: molecular mediators of cardiac development and congenital heart disease Trends Cardiovasc Med 9 1999 11 18
-
(1999)
Trends Cardiovasc Med
, vol.9
, pp. 11-18
-
-
Srivastava, D.1
-
128
-
-
0034648772
-
A genetic blueprint for cardiac development
-
D. Srivastava, and E.N. Olson A genetic blueprint for cardiac development Nature 407 2000 221 226
-
(2000)
Nature
, vol.407
, pp. 221-226
-
-
Srivastava, D.1
Olson, E.N.2
-
129
-
-
0030903857
-
Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
-
D. Srivastava, T. Thomas, Q. Lin, M.L. Kirby, D. Brown, and E.N. Olson Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND Nat Genet 16 1997 154 160
-
(1997)
Nat Genet
, vol.16
, pp. 154-160
-
-
Srivastava, D.1
Thomas, T.2
Lin, Q.3
Kirby, M.L.4
Brown, D.5
Olson, E.N.6
-
130
-
-
0028595708
-
Dpp induces mesodermal gene expression in Drosophila
-
K. Staehling-Hampton, F.M. Hoffmann, M.K. Baylies, E. Rushton, and M. Bate Dpp induces mesodermal gene expression in Drosophila Nature 372 1994 783 786
-
(1994)
Nature
, vol.372
, pp. 783-786
-
-
Staehling-Hampton, K.1
Hoffmann, F.M.2
Baylies, M.K.3
Rushton, E.4
Bate, M.5
-
131
-
-
0036362978
-
Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3′UTR-ires-Cre allele of the homeobox gene Nkx2-5
-
E.G. Stanley, C. Biben, A. Elefanty, L. Barnett, F. Koentgen, and L. Robb Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3′UTR-ires-Cre allele of the homeobox gene Nkx2-5 Int J Dev Biol 46 2002 431 439
-
(2002)
Int J Dev Biol
, vol.46
, pp. 431-439
-
-
Stanley, E.G.1
Biben, C.2
Elefanty, A.3
Barnett, L.4
Koentgen, F.5
Robb, L.6
-
132
-
-
0141615095
-
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
-
F.A. Stennard, M.W. Costa, D.A. Elliott, S. Rankin, S.J. Haast, and D. Lai Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart Dev Biol 262 2003 206 224
-
(2003)
Dev Biol
, vol.262
, pp. 206-224
-
-
Stennard, F.A.1
Costa, M.W.2
Elliott, D.A.3
Rankin, S.4
Haast, S.J.5
Lai, D.6
-
133
-
-
20244365621
-
Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice
-
E. Takimoto, T. Mizuno, F. Terasaki, M. Shimoyama, H. Honda, and I. Shiojima Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice Biochem Biophys Res Commun 270 2000 1074 1079
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 1074-1079
-
-
Takimoto, E.1
Mizuno, T.2
Terasaki, F.3
Shimoyama, M.4
Honda, H.5
Shiojima, I.6
-
134
-
-
0032907924
-
The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development
-
M. Tanaka, Z. Chen, S. Bartunkova, N. Yamasaki, and S. Izumo The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development Development 126 1999 1269 1280
-
(1999)
Development
, vol.126
, pp. 1269-1280
-
-
Tanaka, M.1
Chen, Z.2
Bartunkova, S.3
Yamasaki, N.4
Izumo, S.5
-
135
-
-
0344428124
-
Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5
-
M. Tanaka, S.B. Wechsler, I.W. Lee, N. Yamasaki, J.A. Lawitts, and S. Izumo Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5 Development 126 1999 1439 1450
-
(1999)
Development
, vol.126
, pp. 1439-1450
-
-
Tanaka, M.1
Wechsler, S.B.2
Lee, I.W.3
Yamasaki, N.4
Lawitts, J.A.5
Izumo, S.6
-
136
-
-
0034115494
-
Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting
-
M. Tanaka, N. Yamasaki, and S. Izumo Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting Mol Cell Biol 20 2000 2874 2879
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2874-2879
-
-
Tanaka, M.1
Yamasaki, N.2
Izumo, S.3
-
137
-
-
0034967610
-
Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx
-
M. Tanaka, M. Schinke, H.S. Liao, N. Yamasaki, and S. Izumo Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx Mol Cell Biol 21 2001 4391 4398
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4391-4398
-
-
Tanaka, M.1
Schinke, M.2
Liao, H.S.3
Yamasaki, N.4
Izumo, S.5
-
138
-
-
8444238887
-
Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes
-
H. Terami, K. Hidaka, T. Katsumata, A. Iio, and T. Morisaki Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes Biochem Biophys Res Commun 325 2004 968 975
-
(2004)
Biochem Biophys Res Commun
, vol.325
, pp. 968-975
-
-
Terami, H.1
Hidaka, K.2
Katsumata, T.3
Iio, A.4
Morisaki, T.5
-
139
-
-
0036773644
-
The basic helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene
-
B.D. Thattaliyath, B.A. Firulli, and A.B. Firulli The basic helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene J Mol Cell Cardiol 34 2002 1335 1344
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 1335-1344
-
-
Thattaliyath, B.D.1
Firulli, B.A.2
Firulli, A.B.3
-
140
-
-
0035386434
-
Elevated expression of Nkx-2.5 in developing myocardial conduction cells
-
P.S. Thomas, H. Kasahara, A.M. Edmonson, S. Izumo, M.H. Yacoub, and P.J. Barton Elevated expression of Nkx-2.5 in developing myocardial conduction cells Anat Rec 263 2001 307 313
-
(2001)
Anat Rec
, vol.263
, pp. 307-313
-
-
Thomas, P.S.1
Kasahara, H.2
Edmonson, A.M.3
Izumo, S.4
Yacoub, M.H.5
Barton, P.J.6
-
141
-
-
0031861927
-
Upregulation of the cardiac homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload
-
J.T. Thompson, M.S. Rackley, and T.X. O'Brien Upregulation of the cardiac homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload Am J Physiol 274 1998 H1569 H1573
-
(1998)
Am J Physiol
, vol.274
-
-
Thompson, J.T.1
Rackley, M.S.2
O'Brien, T.X.3
-
142
-
-
0037025368
-
Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart
-
H. Toko, W. Zhu, E. Takimoto, I. Shiojima, Y. Hiroi, and Y. Zou Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart J Biol Chem 277 2002 24735 24743
-
(2002)
J Biol Chem
, vol.277
, pp. 24735-24743
-
-
Toko, H.1
Zhu, W.2
Takimoto, E.3
Shiojima, I.4
Hiroi, Y.5
Zou, Y.6
-
143
-
-
0028294694
-
XNkx- 2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development
-
K.F. Tonissen, T.A. Drysdale, T.J. Lints, R.P. Harvey, and P.A. Krieg XNkx- 2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development Dev Biol 162 1994 325 328
-
(1994)
Dev Biol
, vol.162
, pp. 325-328
-
-
Tonissen, K.F.1
Drysdale, T.A.2
Lints, T.J.3
Harvey, R.P.4
Krieg, P.A.5
-
144
-
-
0029669183
-
Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx
-
D. Turbay, S.B. Wechsler, K.M. Blanchard, and S. Izumo Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx Mol Med 2 1996 86 96
-
(1996)
Mol Med
, vol.2
, pp. 86-96
-
-
Turbay, D.1
Wechsler, S.B.2
Blanchard, K.M.3
Izumo, S.4
-
145
-
-
0035252105
-
Wnt signals from the neural tube block ectopic cardiogenesis
-
E. Tzahor, and A.B. Lassar Wnt signals from the neural tube block ectopic cardiogenesis Genes Dev 15 2001 255 260
-
(2001)
Genes Dev
, vol.15
, pp. 255-260
-
-
Tzahor, E.1
Lassar, A.B.2
-
146
-
-
0345060044
-
Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis
-
T. Ueyama, H. Kasahara, T. Ishiwata, Q. Nie, and S. Izumo Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis Mol Cell Biol 23 2003 9222 9232
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9222-9232
-
-
Ueyama, T.1
Kasahara, H.2
Ishiwata, T.3
Nie, Q.4
Izumo, S.5
-
147
-
-
0041706297
-
Csm, a cardiac-specific isoform of the RNA helicase Mov10l1, is regulated by Nkx2.5 in embryonic heart
-
T. Ueyama, H. Kasahara, T. Ishiwata, N. Yamasaki, and S. Izumo Csm, a cardiac-specific isoform of the RNA helicase Mov10l1, is regulated by Nkx2.5 in embryonic heart J Biol Chem 278 2003 28750 28757
-
(2003)
J Biol Chem
, vol.278
, pp. 28750-28757
-
-
Ueyama, T.1
Kasahara, H.2
Ishiwata, T.3
Yamasaki, N.4
Izumo, S.5
-
148
-
-
0041695485
-
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling
-
M.T. Veeman, J.D. Axelrod, and R.T. Moon A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling Dev Cell 5 2003 367 377
-
(2003)
Dev Cell
, vol.5
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
149
-
-
4544291281
-
Foxh1 is essential for development of the anterior heart field
-
I. von Both, C. Silvestri, T. Erdemir, H. Lickert, J.R. Walls, and R.M. Henkelman Foxh1 is essential for development of the anterior heart field Dev Cell 7 2004 331 345
-
(2004)
Dev Cell
, vol.7
, pp. 331-345
-
-
Von Both, I.1
Silvestri, C.2
Erdemir, T.3
Lickert, H.4
Walls, J.R.5
Henkelman, R.M.6
-
150
-
-
0036848609
-
Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD
-
Y. Watanabe, D.W. Benson, S. Yano, T. Akagi, M. Yoshino, and J.C. Murray Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD J Med Genet 39 2002 807 811
-
(2002)
J Med Genet
, vol.39
, pp. 807-811
-
-
Watanabe, Y.1
Benson, D.W.2
Yano, S.3
Akagi, T.4
Yoshino, M.5
Murray, J.C.6
-
151
-
-
0029149656
-
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
-
G. Winnier, M. Blessing, P.A. Labosky, and B.L. Hogan Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse Genes Dev 9 1995 2105 2116
-
(1995)
Genes Dev
, vol.9
, pp. 2105-2116
-
-
Winnier, G.1
Blessing, M.2
Labosky, P.A.3
Hogan, B.L.4
-
152
-
-
0029000929
-
Heart development in Drosophila requires the segment polarity gene wingless
-
X. Wu, K. Golden, and R. Bodmer Heart development in Drosophila requires the segment polarity gene wingless Dev Biol 169 1995 619 628
-
(1995)
Dev Biol
, vol.169
, pp. 619-628
-
-
Wu, X.1
Golden, K.2
Bodmer, R.3
-
153
-
-
0032145411
-
Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm
-
X. Xu, Z. Yin, J.B. Hudson, E.L. Ferguson, and M. Frasch Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm Genes Dev 12 1998 2354 2370
-
(1998)
Genes Dev
, vol.12
, pp. 2354-2370
-
-
Xu, X.1
Yin, Z.2
Hudson, J.B.3
Ferguson, E.L.4
Frasch, M.5
-
154
-
-
0035891429
-
The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation
-
H. Yamagishi, C. Yamagishi, O. Nakagawa, R.P. Harvey, E.N. Olson, and D. Srivastava The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation Dev Biol 239 2001 190 203
-
(2001)
Dev Biol
, vol.239
, pp. 190-203
-
-
Yamagishi, H.1
Yamagishi, C.2
Nakagawa, O.3
Harvey, R.P.4
Olson, E.N.5
Srivastava, D.6
-
155
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
K. Yamaguchi, K. Shirakabe, H. Shibuya, K. Irie, I. Oishi, and N. Ueno Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction Science 270 1995 2008 2011
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
-
156
-
-
0029850112
-
Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
-
H. Zhang, and A. Bradley Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development Development 122 1996 2977 2986
-
(1996)
Development
, vol.122
, pp. 2977-2986
-
-
Zhang, H.1
Bradley, A.2
-
157
-
-
0034634624
-
Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease
-
W. Zhu, I. Shiojima, Y. Hiroi, Y. Zou, H. Akazawa, and M. Mizukami Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease J Biol Chem 275 2000 35291 35296
-
(2000)
J Biol Chem
, vol.275
, pp. 35291-35296
-
-
Zhu, W.1
Shiojima, I.2
Hiroi, Y.3
Zou, Y.4
Akazawa, H.5
Mizukami, M.6
-
158
-
-
0031029447
-
CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway
-
Y. Zou, S. Evans, J. Chen, H.C. Kuo, R.P. Harvey, and K.R. Chien CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway Development 124 1997 793 804
-
(1997)
Development
, vol.124
, pp. 793-804
-
-
Zou, Y.1
Evans, S.2
Chen, J.3
Kuo, H.C.4
Harvey, R.P.5
Chien, K.R.6
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