-
4
-
-
0030587603
-
NK-2 homeobox genes and heart development
-
(1996)
Dev Biol
, vol.178
, pp. 203-216
-
-
Harvey, R.P.1
-
5
-
-
0031805612
-
Vertebrate homologs of tinman and bagpipe: Roles of the homeobox genes in cardiovascular development
-
(1998)
Dev Genet
, vol.22
, pp. 239-249
-
-
Tanaka, M.1
Kasahara, H.2
Bartunkova, S.3
Schinke, M.4
Komuro, I.5
Inagaki, H.6
Lee, Y.7
Lyons, G.E.8
Izumo, S.9
-
8
-
-
0034650311
-
Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand
-
(2000)
Dev Biol
, vol.217
, pp. 266-277
-
-
Bruneau, B.G.1
Bao, Z.Z.2
Tanaka, M.3
Schott, J.J.4
Izumo, S.5
Cepko, C.L.6
Seidman, J.G.7
Seidman, C.E.8
-
9
-
-
0034663328
-
Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera
-
(2000)
Dev Biol
, vol.224
, pp. 152-167
-
-
Wang, C.C.1
Biben, C.2
Robb, L.3
Nassir, F.4
Barnett, L.5
Davidson, N.O.6
Koentgen, F.7
Tarlinton, D.8
Harvey, R.P.9
-
14
-
-
0032380010
-
Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5
-
(1998)
Dev Biol
, vol.204
, pp. 187-196
-
-
Grow, M.W.1
Krieg, P.A.2
-
16
-
-
13144257684
-
Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9366-9371
-
-
Park, M.1
Lewis, C.2
Turbay, D.3
Chung, A.4
Chen, J.N.5
Evans, S.6
Breitbart, R.E.7
Fishman, M.C.8
Izumo, S.9
Bodmer, R.10
-
17
-
-
0035967868
-
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor
-
(2001)
Cell
, vol.105
, pp. 851-862
-
-
Wang, D.1
Chang, P.S.2
Wang, Z.3
Sutherland, L.4
Richardson, J.A.5
Small, E.6
Krieg, P.A.7
Olson, E.N.8
-
19
-
-
0030916211
-
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
-
(1997)
Genes Dev
, vol.11
, pp. 1048-1060
-
-
Kuo, C.T.1
Morrisey, E.E.2
Anandappa, R.3
Sigrist, K.4
Lu, M.M.5
Parmacek, M.S.6
Soudais, C.7
Leiden, J.M.8
-
26
-
-
0031032654
-
Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors
-
(1997)
EMBO J
, vol.16
, pp. 355-368
-
-
Gove, C.1
Walmsley, M.2
Nijjar, S.3
Bertwistle, D.4
Guille, M.5
Partington, G.6
Bomford, A.7
Patient, R.8
-
38
-
-
0034662018
-
Chamber formation and morphogenesis in the developing mammalian heart
-
(2000)
Dev Biol
, vol.223
, pp. 266-278
-
-
Christoffels, V.M.1
Habets, P.E.2
Franco, D.3
Campione, M.4
De Jong, F.5
Lamers, W.H.6
Bao, Z.Z.7
Palmer, S.8
Biben, C.9
Harvey, R.P.10
Moorman, A.F.11
-
40
-
-
0035133913
-
Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1730-1736
-
-
Bruneau, B.G.1
Bao, Z.Z.2
Fatkin, D.3
Xavier-Neto, J.4
Georgakopoulos, D.5
Maguire, C.T.6
Berul, C.I.7
Kass, D.A.8
Kuroski-de Bold, M.L.9
De Bold, A.J.10
Conner, D.A.11
Rosenthal, N.12
Cepko, C.L.13
Seidman, C.E.14
Seidman, J.G.15
-
42
-
-
0032808941
-
A retinoic acid-inducible transgenic marker of sino-atrial development in the mouse heart
-
(1999)
Development
, vol.126
, pp. 2677-2687
-
-
Xavier-Neto, J.1
Neville, C.M.2
Shapiro, M.D.3
Houghton, L.4
Wang, G.F.5
Nikovits, W.6
Stockdale, F.E.7
Rosenthal, N.8
-
46
-
-
0032715827
-
HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
-
(1999)
Dev Biol
, vol.216
, pp. 72-84
-
-
Nakagawa, O.1
Nakagawa, M.2
Richardson, J.A.3
Olson, E.N.4
Srivastava, D.5
-
48
-
-
0034011764
-
Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system
-
(2000)
J Biol Chem
, vol.275
, pp. 6381-6387
-
-
Chin, M.T.1
Maemura, K.2
Fukumoto, S.3
Jain, M.K.4
Layne, M.D.5
Watanabe, M.6
Hsieh, C.M.7
Lee, M.E.8
-
51
-
-
0030926451
-
Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development
-
(1997)
Genes Dev
, vol.11
, pp. 1357-1369
-
-
Biben, C.1
Harvey, R.P.2
-
61
-
-
17944378083
-
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.G.1
Nemer, G.2
Schmitt, J.P.3
Charron, F.4
Robitaille, L.5
Caron, S.6
Conner, D.7
Gessler, M.8
Nemer, M.9
Seidman, C.E.10
Seidman, J.G.11
-
65
-
-
17744395906
-
TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome
-
(2001)
Cell
, vol.104
, pp. 619-629
-
-
Merscher, S.1
Funke, B.2
Epstein, J.A.3
Heyer, J.4
Puech, A.5
Lu, M.M.6
Xavier, R.J.7
Demay, M.B.8
Russell, R.G.9
Factor, S.10
Tokooya, K.11
St. Jore, B.12
Lopez, M.13
Pandita, R.K.14
Lia, M.15
Carrion, D.16
Xu, H.17
Schorle, H.18
Kobler, J.B.19
Scambler, P.J.20
Wynshaw-Boris, A.21
Skoultchi, A.I.22
Morrow, B.E.23
Kucherlapati, R.24
more..
-
66
-
-
0034947445
-
Progressive atrioventricular conduction defects and heart failure in mice overexpressing a mutant Csx/NLx2.5 homeoprotein
-
(2001)
J Clin Invest
, vol.108
, pp. 189-201
-
-
Kasahara, H.1
Wakimoto, H.2
Liu, M.3
Maguire, C.T.4
Converso, K.L.5
Shioi, T.6
Huang, W.-Y.7
Manning, W.J.8
Paul, D.9
Lawitts, J.10
Berul, C.I.11
Izumo, S.12
-
68
-
-
0034234675
-
Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development
-
(2000)
Mech Dev
, vol.95
, pp. 231-237
-
-
Angelo, S.1
Lohr, J.2
Lee, K.H.3
Ticho, B.S.4
Breitbart, R.E.5
Hill, S.6
Yost, H.J.7
Srivastava, D.8
-
71
-
-
0032479573
-
Congenital heart disease caused by mutations in the transcription factor NKX2-5
-
(1998)
Science
, vol.281
, pp. 108-111
-
-
Schott, J.-J.1
Benson, D.W.2
Basson, C.T.3
Pease, W.4
Silberbach, G.M.5
Moak, J.P.6
Maron, B.7
Seidman, C.E.8
Seidman, J.G.9
-
72
-
-
0033430230
-
Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
-
(1999)
J Clin Invest
, vol.104
, pp. 1567-1573
-
-
Benson, D.W.1
Silberbach, G.M.2
Kavanaugh-McHugh, A.3
Cottrill, C.4
Zhang, Y.5
Riggs, S.6
Smalls, O.7
Johnson, M.C.8
Watson, M.S.9
Seidman, J.G.10
Seidman, C.E.11
Plowden, J.12
Kugler, J.D.13
-
75
-
-
0034634279
-
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5
-
(2000)
Circ Res
, vol.87
, pp. 888-895
-
-
Biben, C.1
Weber, R.2
Kesteven, S.3
Stanley, E.4
McDonald, L.5
Elliott, D.A.6
Barnett, L.7
Koentgen, F.8
Robb, L.9
Feneley, M.10
Harvey, R.P.11
-
76
-
-
0030636780
-
Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome
-
(1997)
Nat Genet
, vol.15
, pp. 30-35
-
-
Basson, C.T.1
Bachinsky, D.R.2
Lin, R.C.3
Levi, T.4
Elkins, J.A.5
Soults, J.6
Grayzel, D.7
Kroumpouzou, E.8
Traill, T.A.9
Leblanc-Straceski, J.10
Renault, B.11
Kucherlapati, R.12
Seidman, J.G.13
Seidman, C.E.14
-
77
-
-
1842413728
-
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
-
(1997)
Nat Genet
, vol.15
, pp. 21-29
-
-
Li, Q.Y.1
Newbury-Ecob, R.A.2
Terrett, J.A.3
Wilson, D.I.4
Curtis, A.R.5
Yi, C.H.6
Gebuhr, T.7
Bullen, P.J.8
Robson, S.C.9
Strachan, T.10
Bonnet, D.11
Lyonnet, S.12
Young, I.D.13
Raeburn, J.A.14
Buckler, A.J.15
Law, D.J.16
Brook, J.D.17
-
78
-
-
13044287363
-
Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2919-2924
-
-
Basson, C.T.1
Huang, T.2
Lin, R.C.3
Bachinsky, D.R.4
Weremowicz, S.5
Vaglio, A.6
Bruzzone, R.7
Quadrelli, R.8
Lerone, M.9
Romeo, G.10
Silengo, M.11
Pereira, A.12
Krieger, J.13
Mesquita, S.F.14
Kamisago, M.15
Morton, C.C.16
Pierpont, M.E.17
Muller, C.W.18
Seidman, J.G.19
Seidman, C.E.20
more..
-
79
-
-
0033788894
-
The mutation spectrum in Holt-Oram syndrome
-
(2000)
J Med Genet
, vol.37
, pp. 785-787
-
-
Cross, S.J.1
Ching, Y.-H.2
Li, Q.Y.3
Armstrong-Buisseret, L.4
Spranger, S.5
Lyonnet, S.6
Bonnet, D.7
Penttinen, M.8
Jonveaux, P.9
Leheup, B.10
Mortier, G.11
Van Ravenswaaij, C.12
Gardiner, C.-A.13
Brook, J.D.14
Newbury-Ecob, R.A.15
-
82
-
-
0033387975
-
Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism
-
(1999)
Development
, vol.126
, pp. 5749-5758
-
-
Kitamura, K.1
Miura, H.2
Miyagawa-Tomita, S.3
Yanazawa, M.4
Katoh-Fukui, Y.5
Suzuki, R.6
Ohuchi, H.7
Suehiro, A.8
Motegi, Y.9
Nakahara, Y.10
Kondo, S.11
Yokoyama, M.12
-
83
-
-
0033575971
-
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis
-
(1999)
Nature
, vol.401
, pp. 279-282
-
-
Lin, C.R.1
Kioussi, C.2
O'Connell, S.3
Briata, P.4
Szeto, D.5
Liu, F.6
Izpisua-Belmonte, J.C.7
Rosenfeld, M.G.8
-
86
-
-
0034705318
-
FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium
-
(2000)
Cell
, vol.101
, pp. 729-739
-
-
Tevosian, S.G.1
Deconinck, A.E.2
Tanaka, M.3
Schinke, M.4
Litovsky, S.H.5
Izumo, S.6
Fujiwara, Y.7
Orkin, S.H.8
-
87
-
-
0033945862
-
A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2
-
(2000)
Nat Genet
, vol.25
, pp. 353-356
-
-
Svensson, E.C.1
Huggins, G.S.2
Lin, H.3
Clendenin, C.4
Jiang, F.5
Tufts, R.6
Dardik, F.B.7
Leiden, J.M.8
-
89
-
-
0028168007
-
Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis
-
(1994)
Cell
, vol.78
, pp. 987-1003
-
-
Kastner, P.1
Grondona, J.M.2
Mark, M.3
Gansmuller, A.4
LeMeur, M.5
Decimo, D.6
Vonesch, J.L.7
Dolle, P.8
Chambon, P.9
-
90
-
-
0029780320
-
RXRα deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice
-
(1996)
J Clin Invest
, vol.98
, pp. 1332-1343
-
-
Gruber, P.J.1
Kubalak, S.W.2
Pexieder, T.3
Sucov, H.M.4
Evans, R.M.5
Chien, K.R.6
-
92
-
-
0031470903
-
Vitamin A deficiency and mutations of RXRα, RXRβ and RARα lead to early differentiation of embryonic ventricular cardiomyocytes
-
(1997)
Development
, vol.124
, pp. 4749-4758
-
-
Kastner, P.1
Messaddeq, N.2
Mark, M.3
Wendling, O.4
Grondona, J.M.5
Ward, S.6
Ghyselinck, N.7
Chambon, P.8
-
93
-
-
0031596654
-
The RXRα gene functions in a non-cell-autonomous manner during mouse cardiac morphogenesis
-
(1998)
Development
, vol.125
, pp. 1951-1956
-
-
Tran, C.1
Sucov, H.2
-
94
-
-
0031799964
-
Ventricular muscle-restricted targeting of the RXRα gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis
-
(1998)
Development
, vol.125
, pp. 1943-1949
-
-
Chen, J.1
Kubalak, S.2
Chien, K.R.3
-
100
-
-
0032510493
-
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
-
(1998)
Nature
, vol.392
, pp. 182-186
-
-
De la Pompa, J.L.1
Timmerman, L.A.2
Takimoto, H.3
Yoshida, H.4
Elia, A.J.5
Samper, E.6
Potter, J.7
Wakeham, A.8
Marengere, L.9
Langille, B.L.10
Crabtree, G.R.11
Mak, T.W.12
-
101
-
-
0032510581
-
The transcription factor NF-ATc is essential for cardiac valve formation
-
(1998)
Nature
, vol.392
, pp. 186-190
-
-
Ranger, A.M.1
Grusby, M.J.2
Hodge, M.R.3
Gravallese, E.M.4
De la Brousse, F.C.5
Hoey, T.6
Mickanin, C.7
Baldwin, H.S.8
Glimcher, L.H.9
-
102
-
-
18344389337
-
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator
-
(2001)
Nat Genet
, vol.29
, pp. 469-474
-
-
Bamforth, S.D.1
Bragança, J.2
Eloranta, J.J.3
Murdoch, J.N.4
Marques, F.I.R.5
Kranc, K.R.6
Farza, H.7
Henderson, D.J.8
Hurst, H.C.9
Bhattacharya, S.10
-
105
-
-
0034264850
-
A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages
-
(2000)
Cell
, vol.102
, pp. 671-682
-
-
Nguyen-Tran, V.T.1
Kubalak, S.W.2
Minamisawa, S.3
Fiset, C.4
Wollert, K.C.5
Brown, A.B.6
Ruiz-Lozano, P.7
Barrere-Lemaire, S.8
Kondo, R.9
Norman, L.W.10
Gourdie, R.G.11
Rahme, M.M.12
Feld, G.K.13
Clark, R.B.14
Giles, W.R.15
Chien, K.R.16
-
110
-
-
17744364498
-
Two-step regulation of left-right asymmetric expression of Pitx2: Initiation by nodal signaling and maintenance by Nkx2
-
(2001)
Mol Cell
, vol.7
, pp. 137-149
-
-
Shiratori, H.1
Sakuma, R.2
Watanabe, M.3
Hashiguchi, H.4
Mochida, K.5
Sakai, Y.6
Nishino, J.7
Saijoh, Y.8
Whitman, M.9
Hamada, H.10
-
118
-
-
0035912754
-
The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7342-7347
-
-
Fossett, N.1
Tevosian, S.G.2
Gajewski, K.3
Zhang, Q.4
Orkin, S.H.5
Schulz, R.A.6
-
120
-
-
0033583178
-
Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4
-
(1999)
J Biol Chem
, vol.274
, pp. 8231-8239
-
-
Shiojima, I.1
Komuro, I.2
Oka, T.3
Hiroi, Y.4
Mizuno, T.5
Takimoto, E.6
Monzen, K.7
Aikawa, R.8
Akazawa, H.9
Yamazaki, T.10
Kudoh, S.11
Yazaki, Y.12
-
124
-
-
0000634381
-
Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac α-actin gene transcription
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6372-6384
-
-
Chen, C.Y.1
Schwartz, R.J.2
-
126
-
-
0035008873
-
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2085-2097
-
-
Kuwahara, K.1
Saito, Y.2
Ogawa, E.3
Takahashi, N.4
Nakagawa, Y.5
Naruse, Y.6
Harada, M.7
Hamanaka, I.8
Izumi, T.9
Miyamoto, Y.10
Kishimoto, I.11
Kawakami, R.12
Nakanishi, M.13
Mori, N.14
Nakao, K.15
-
131
-
-
17644445419
-
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
-
(1998)
Cell
, vol.93
, pp. 361-372
-
-
Yao, T.P.1
Oh, S.P.2
Fuchs, M.3
Zhou, N.D.4
Ch'ng, L.E.5
Newsome, D.6
Bronson, R.T.7
Li, E.8
Livingston, D.M.9
Eckner, R.10
-
132
-
-
0035887278
-
Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA
-
(2001)
Genes Dev
, vol.15
, pp. 2702-2719
-
-
Charron, F.1
Tsimiklis, G.2
Arcand, M.3
Robitaille, L.4
Liang, Q.5
Molkentin, J.D.6
Meloche, S.7
Nemer, M.8
-
133
-
-
0034883426
-
Rho kinases play an obligatory role in vertebrate embryonic organogenesis
-
(2001)
Development
, vol.128
, pp. 2953-2962
-
-
Wei, L.1
Roberts, W.2
Wang, L.3
Yamada, M.4
Zhang, S.5
Zhao, Z.6
Rivkees, S.A.7
Schwartz, R.J.8
Imanaka-Yoshida, K.9
-
134
-
-
0032959891
-
Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tissue-specifying homeobox gene product Csx/Nkx2.5
-
(1999)
Mol Cell Biol
, vol.19
, pp. 526-536
-
-
Kasahara, H.1
Izumo, S.2
-
136
-
-
19244386873
-
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
-
(2000)
J Clin Invest
, vol.105
, pp. 1395-1406
-
-
Passier, R.1
Zeng, H.2
Frey, N.3
Naya, F.J.4
Nicol, R.L.5
McKinsey, T.A.6
Overbeek, P.7
Richardson, J.A.8
Grant, S.R.9
Olson, E.N.10
|