CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway

Development

Volumn 124, Issue 4, 1997, Pages 793-804

  Zou, Yimin ^a,d   Evans, Sylvia ^a   Chen, Ju ^a   Kuo, Hai Chien ^a   Harvey, Richard P ^b   Chien, Kenneth R ^a,c  

^a AMERICAN HEART ASSOCIATION   (United States)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Ankyrin repeats; Heart development; Homeobox gene; Mouse; Myosin light chain 2v; Nkx2 5; tinman; Transcription regulation; YB 1

Indexed keywords

ANKYRIN; COMPLEMENTARY DNA; LUCIFERASE; MESSENGER RNA; MYOSIN LIGHT CHAIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA LIBRARY; DNA TRANSFECTION; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE ISOLATION; GENE LOCATION; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART VENTRICLE; HOMEOBOX; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; MOUSE; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; RAT; REGULATOR GENE; REPORTER GENE; SKELETAL MUSCLE; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION; TRANSGENE;

AMINO ACID SEQUENCE; ANIMALS; ANKYRIN REPEAT; BASE SEQUENCE; CCAAT-ENHANCER-BINDING PROTEINS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HEART; HOMEODOMAIN PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; MYOCARDIUM; NFI TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); RATS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS PROTEINS; Y-BOX-BINDING PROTEIN 1;

ANIMALIA; CYPRINUS CARPIO; MAMMALIA; MURINAE;

EID: 0031029447     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. Azpiazu, N. and Frasch, M. (1993). tinman and bag pipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7(7B), 1325-1340.
2. Badiani, P, Corbella, P, Kioussis, D, Marvel, J and Weston, K. (1994). Dominant interfering alleles define a role for c-Myb in T-cell development. Genes Dev. 8, 770-782.
3. Becker, K.D., O'Donnell, P. T., Heitz, J. M., Vito, M. and Bernstein, S. I. (1992). Analysis of Drosophila paramyosin: identification of a novel isoform which is restricted to a subset of adult muscles. J. Cell. Biol. 116, 669-681.
4. Bodmer, R. (1993). The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118, 719-729.
5. Bodmer, R. (1995). Heart development in Drosophila and its relationship to vertebrates. Trends Cardiovasc. Med. 5, 21-28.
6. Chen, C. and Okayama, H. (1987). High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752.
7. Chien, K. R., Zhu, H., Knowlton, K. U., Miller-Hance, W., van Bilsen, M., O'Brien, T. X. and Evans, S. M. (1993). Transcriptional regulation during cardiac growth and development. Annu. Rev. Physiol. 55, 77-95.
8. Chu, W., Burns, D. K., Swerlick, R. A. and Presky, D. H. (1995). Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells. J. Biol. Chem. 270, 10236-10245.
9. Conlon, F. L., Sedgwick, S. G., Weston, K. M. and Smith, J. C. (1996). Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 122, 2427-2435.
10. Cserjesi, P., Brown, D., Lyons, G.E. and Olson, E. N. (1995). Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extra embryonic membranes during mouse development. Dev. Biol. 170, 644-678.
11. Dyson, E., Sucov, H., Kubalak, S. W., Schmid-Schönbein, G., Delano, F., Evans, R. M., Ross, J., Jr. and Chien, K. R. (1995). Atrial-like phenotype is associated with embryonic ventricular failure in RXRa -/-mice. Proc. Natl. Acad. Sci. USA 92, 7386-7390.
12. Edmondson, D. G., Lyons, G. E., Martin, J. F. and Olson, E. N. (1994). Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development 120, 1251-1263.
13. Evans, S. M., Tai, L-J., Tan, V. P., Newton, C. B. and Chien, K. R. (1994). Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype. Mol. Cell. Biol. 14, 4269-4279.
14. Evans, S. M., Yan, W., Murillo, M. P., Ponce, J. and Papalopulu, N. (1995). tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman. Development 121, 3889-3899.
15. Garcia-Martinez, V. and Schoenwolf, G. C. (1993). Primitive streak origin of the cardiovascular system in avian embryos. Dev. Biol. 159, 706-719.
16. Gassmann, M., Casagranda, F., Orioli, D., Simon, H., Lai, C., Klein, R. and Lemke, G. (1995). Aberrant neural and cardiac development in mice lacking the erbB4 neuregulin receptor. Nature 378, 39-394.
17. Grant, C. E. and Deeley, R. G. (1993). Cloning and characterization of chicken YB-1: regulation of expression in the liver. Mol. Cell. Biol. 13, 4186-4196.
18. Grepin, C., Robitaille, L., Antakly, T. and Nemer, M. (1995). Inhibition of transcription factor GATA-4 expression blocks in vitro cardiac muscle differentiation. Mol. Cell. Biol. 15, 4095-5012.
19. Gruber, P. J., Kubalak, S. W., Pexieder, T., Sucov, H. M., Evans, R. M. and Chien, K. R. (1996). RXRalpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice. J. Clin. Invest. 98, 1332-1343.
20. Gyuris, J., Golemis, E., Chertkov, H. and Brent, R. (1993). Cdi1, a human G1 and S phase protein phosphatase that associates with cdk2. Cell 75, 791-803.
21. Han, K and Manley, J. L. (1993). Functional domains of the Drosophila engrailed protein. EMBO J. 12, 2723-2733.
22. Jaber, M., Koch, W. J., Rockman, H. A., Smith, B., Bond, R. A., Sulik, K., Ross, J., Jr., Lefkowitz, R. J., Caron, M. G. and Giros, B. (1996). Targeted disruption of the ß-adrenergic receptor kinase 1 gene in mice demonstrates essential roles in cardiac development and function. Proc Natl Acad Sci USA, In Press.
23. Jaynes, J. B. and O'Farrell, P. H. (1991). Active repression of transcription by the Engrailed homeodomain protein. EMBO J. 10, 1427-1433.
24. Jiang, Y. and Evans, T. (1996). The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Dev. Biol. 174, 258-270.
25. John, A., Smith, S. T. and Jaynes, B. (1995). Inserting the Ftz homeodomain into Engrailed creates a dominant transcriptional repressor that specifically turns off Ftz target genes in vivo. Development 121, 1801-1813.
26. Jones, W. K., Sanchez, A. and Robbins, J. (1994). Murine pulmonary myocardium: developmental analysis of cardiac gene expression. Dev. Dynamics 200, 117-28.
27. Komuro, I. and Izumo, S. (1993). Csx: a murine homeobox-containing gene specifically expressed in the developing heart. Proc. Natl. Acad. Sci. USA 90, 8145-8149.
28. Kubalak, S. W., Miller-Hance, W. C., O'Brien, T. X., Dyson, E. and Chien, K. R. (1994). Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. J. Biol. Chem. 269, 16961-16970.
29. LaMarco, K., Thompson, C. C., Byers, B. P., Walton, E. M. and McKnight, S. L. (1991). Identification of ETS-related and Notch-related subunits in GA binding protein. Science 253, 789-792.
30. Lee, K-H, Xu, Q. and Breitbart, R. E. (1996). A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. Dev. Biol., In Press.
31. Lee, K. F., Simon, H, Chen, H, Bates, B., Hung, M. C., Hauser, C. (1995) Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 378, 394-398.
32. Lee, K. J., Hickey, R., Zhu, H. and Chien, K. R. (1994). Positive regulatory elements (HF-1a and HF-1b) and a novel, negative regulatory element (HF-3) mediate ventricular muscle-specific expression of myosin light-chain 2-luciferase fusion genes in transgenic mice. Mol. Cell. Biol. 14, 1220-1229.
33. Lee, K. J., Ross, R. S., Rockman, H. A., Harris, A., O'Brien, T. X., van Bilsen, M., Shubeita, H., Kandolf, R., Brem, G., Price, J., Evans, S. M., Zhu, H., Franz, W. M. and Chien, K. R. (1992). Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. J. Biol. Chem. 267, 15875-15885.
34. Lilly, B., Zhao, B., Ranganayakulu, G., Paterson, B. M., Schulz, R. A. and Olson, E. N.. (1995). Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila. Science 267, 688-693.
35. Lints, T. J., Parsons, L. M., Hartley, L., Lyons, I. and Harvey, R. P. (1993). Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119, 419-431.
36. Lyons, G. E., Buckingham, M. E., Tweedie, S. and Edwards, Y. H. (1991a). Carbonic anhydrase-III, an early mesodermal marker, is expressed in embryonic mouse skeletal muscle and notochord. Development 111, 233-244.
37. Lyons, G. E., Muhlebach S., Moser A., Masood, R., Paterson, B. M., Buckingham, M. E. and Perriard, J-C. (1991b). Developmental regulation of creatine kinase gene expression by myogenic factors in embryonic mouse and chick skeletal muscle. Development 113, 1017-1029.
38. Lyons, G. E., Schiaffino S., Sassoon D., Barton P. and Buckingham, M. (1990). Developmental regulation of myosin gene expression in mouse cardiac muscle. J. Cell Biol. 111, 2427-2436.
39. Lyons, I., Parsons, L. M., Hartley, L., Li, R., Andrews, J. E., Robb, L. and Harvey, R. P. (1995). Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev. 9, 1654-1666.
40. Meyer, D. and Birchmeier, C. (1995). Multiple essential functions of neuregulin in development. Nature 378, 386-390.
41. Navankasattusas, S., Sawadogo, M., van Bilsen, M., Dang, C. V. and Chien, K. R. (1994). The basic helix-loop-helix protein upstream stimulating factor regulates the cardiac ventricular myosin lignt-chain 2 gene via independent cis regulatory elements. Mol. Cell. Biol. 14, 7331-7339.
42. Navankasattusas, S., Zhu, H., Garcia, A., Evans, S. M. and Chien, K. R. (1992). A ubiquitous factor (HF-1A) and a distinct muscle factor (HF-1b/MEF-2) form an E-box-independent pathway for cardiac muscle gene expression. Mol. Cell. Biol. 12, 1469-1479.
43. O'Brien, T. X., Lee, K. J. and Chien, K. R. (1993). Positional specification of ventricular myosin light chain-2 expression in the primitive murine heart tube. Proc. Natl. Acad. Sci. USA 90, 5157-5161.
44. O'Donnell, P. T., Collier, V. L., Mogami, K. and Bernstein, S. I. (1989). Ultra structural and molecular analysis of homozygous-viable Drosophila melanogaster muscle mutants indicate there is a complex pattern of myosin heavy-chain isoform distribution. Genes Dev. 3, 1233-1246.
45. Olson, E. N. and Srivastava, D. (1996). Molecular Pathways controlling heart development. Science 272, 671-676.
46. Rosenquist, G. C. and DeHaan, R. L. (1966). Migration of precardiac cells in the chick embryo: a radioautographic study. Carnegie Inst. Wash. Contrib. Embryol. 38, 111-121.
47. Ross, R. S., Navankasattusas, S., Harvey, R. P. and Chien, K. R. (1996). An HF-1a/HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and establishes an anterior-posterior gradient of expression. Development 122, 1799-1809.
48. Ruiz-Lozano, P., De Lecea, L., Buesa, C., de la Osa, P. P., LaPage, D., Gualberto, A., Walsh, K. and Pons, G. (1994). The gene encoding rat phosphoglycerate mutase subunit M: cloning and promoter analysis in skeletal muscle cells. Gene 147, 243-248.
49. Sater, A. K. and Jacobson, A. G. (1990). The role of the dorsal lip in induction of heart mesoderm in Xenopus laevis. Development 108, 461-470.
50. Schultheiss, T., Xydas, S. and Lassar, A. B. (1995). Induction of avian cardiac myogenesis by anterior endoderm. Development 121, 4203-4214.
51. Sheng, Z., Pennica, D., Wood, W. I. and Chien, K. R. (1996). Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac survival. Development 122, 419-428.
52. Sucov, H. M., Dyson, E., Gumeringer, C. L., Price, J., Chien, K. R. and Evans, R. M. (1994). RXRa mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev 8, 1007-1018.
53. Tonissen, K. F., Drysdale, T. A., Lints, T. J., Harvey, R. P. and Krieg, P. A. (1993). XNkx2-5, a Xenopus gene related to Nkx2-5 and tinman-evidence of a conserved role in cardiac development. Dev. Biol. 162, 325-328.
54. Wilens, S. (1955). The migration of heart mesoderm and associated areas in Amblystoma punctatum. J. Exp. Zool. 129, 579-605.
55. Wilkinson, D. G. (1992). In situ hybridization. IRL Press 61, 61-74.
56. Wolffe, A. P., Tafuri, S., Ranjan, M. and Familari, M. (1992). The Y-box factors-a family of nucleic acid binding proteins conserved from Escherichia coli to Man. New Biol. 4, 290-298.
57. Zhu, H., Garcia, A. V., Ross, R. S., Evans, S. M. and Chien, K. R. (1991). A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light chain-2 gene confers cardiac-specific and alpha-adrenergic inducible expression in cultured neonatal rat myocardial cells. Mol. Cell. Biol. 11, 2273-2281.
58. Zou, Y. and Chien, K. R. (1995). EFIA/YB-1 is a component of cardiac HF-1a binding activity and positively regulates transcription of the myosin light chain-2v gene. Mol. Cell. Biol. 15, 2972-2982.