-
1
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
4S-study-group
-
S-study-group. 1994. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 344(8934):1383-1389.
-
(1994)
Lancet
, vol.344
, Issue.8934
, pp. 1383-1389
-
-
-
2
-
-
0034066646
-
Alzheimer's disease and vascular dementia. Some points of confluence
-
Aguero-Torres H, Winblad B. 2000. Alzheimer's disease and vascular dementia. Some points of confluence. Ann NY Acad Sci 903:547-552.
-
(2000)
Ann. NY Acad. Sci.
, vol.903
, pp. 547-552
-
-
Aguero-Torres, H.1
Winblad, B.2
-
3
-
-
0020007559
-
The role of apolipoproteins in lipid transport processes
-
Alaupovic P. 1982. The role of apolipoproteins in lipid transport processes. Ric Clin Lab 12(1):3-21.
-
(1982)
Ric. Clin. Lab.
, vol.12
, Issue.1
, pp. 3-21
-
-
Alaupovic, P.1
-
4
-
-
0032557425
-
Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis
-
Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush AI. 1998. Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. J Biol Chem 273(21):12817-12826.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.21
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.C.4
Bacarra, N.M.5
Romano, D.M.6
Hartshorn, M.A.7
Tanzi, R.E.8
Bush, A.I.9
-
5
-
-
0031278270
-
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition
-
Bales KR, Verina T, Dodel RC, Du Y, Altstiel L, Bender M, Hyslop P, Johnstone EM, Little SP, Cummins DJ, Piccardo P, Ghetti B, Paul SM. 1997. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat Genet 17(3):263-264.
-
(1997)
Nat. Genet.
, vol.17
, Issue.3
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
Hyslop, P.7
Johnstone, E.M.8
Little, S.P.9
Cummins, D.J.10
Piccardo, P.11
Ghetti, B.12
Paul, S.M.13
-
6
-
-
0031882562
-
Beta-amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons
-
Beffert U, Aumont N, Dea D, Lussier Cacan S, Davignon J, Poirier J. 1998. Beta-amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons. J Neurochem 70(4):1458-1466.
-
(1998)
J. Neurochem.
, vol.70
, Issue.4
, pp. 1458-1466
-
-
Beffert, U.1
Aumont, N.2
Dea, D.3
Lussier Cacan, S.4
Davignon, J.5
Poirier, J.6
-
7
-
-
0033532373
-
Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures
-
Beffert U, Aumont N, Dea D, Lussier-Cacan S, Davignon J, Poirier J. 1999. Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures. Brain Res Mol Brain Res 68(1-2):181-185.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.68
, Issue.1-2
, pp. 181-185
-
-
Beffert, U.1
Aumont, N.2
Dea, D.3
Lussier-Cacan, S.4
Davignon, J.5
Poirier, J.6
-
8
-
-
0030009670
-
Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease
-
Beffert U, Poirier J. 1996. Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease. Ann NY Acad Sci 777:166-174.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 166-174
-
-
Beffert, U.1
Poirier, J.2
-
9
-
-
0032487497
-
ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation
-
Beffert U, Poirier J. 1998. ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation. Neuroreport 9(14):3321-3323.
-
(1998)
Neuroreport
, vol.9
, Issue.14
, pp. 3321-3323
-
-
Beffert, U.1
Poirier, J.2
-
10
-
-
0032751475
-
Genetic testing for Alzheimer's disease: How close is reality?
-
Blennow K, Skoog I. 1999. Genetic testing for Alzheimer's disease: How close is reality? Curr Opin Psychiatry 12:487-493.
-
(1999)
Curr. Opin. Psychiatry
, vol.12
, pp. 487-493
-
-
Blennow, K.1
Skoog, I.2
-
11
-
-
0034068864
-
Statins: Effective antiatherosclerotic therapy
-
Blumenthal RS. 2000. Statins: Effective antiatherosclerotic therapy. Am Heart J 139(4):577-583.
-
(2000)
Am. Heart J.
, vol.139
, Issue.4
, pp. 577-583
-
-
Blumenthal, R.S.1
-
12
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz S, Klein WL. 1996. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271(8):4436-4440.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.8
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
13
-
-
0036015984
-
Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes
-
Bonn V, Cheung RC, Chen B, Taghibiglou C, Van Iderstine SC, Adeli K. 2002. Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes. Atherosclerosis 163(1):59-68.
-
(2002)
Atherosclerosis
, vol.163
, Issue.1
, pp. 59-68
-
-
Bonn, V.1
Cheung, R.C.2
Chen, B.3
Taghibiglou, C.4
Van Iderstine, S.C.5
Adeli, K.6
-
14
-
-
2542523048
-
Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzheimer Disease: From risk factors to disease modulators
-
Borroni B, Archetti S, Agosti C, Akkawi N, Brambilla C, Caimi L, Caltagirone C, Di Luca M, Padovani A. 2004. Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzheimer Disease: From risk factors to disease modulators. Neurobiol Aging 25(6):747-751.
-
(2004)
Neurobiol. Aging
, vol.25
, Issue.6
, pp. 747-751
-
-
Borroni, B.1
Archetti, S.2
Agosti, C.3
Akkawi, N.4
Brambilla, C.5
Caimi, L.6
Caltagirone, C.7
Di Luca, M.8
Padovani, A.9
-
15
-
-
0024574009
-
A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve
-
Boyles JK, Zoellner CD, Anderson LJ, Kosik LM, Pitas RE, Weisgraber KH, Hui DY, Mahley RW, Gebicke-Haerter PJ, Ignatius MJ, et al. 1989. A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J Clin Invest 83(3):1015-1031.
-
(1989)
J. Clin. Invest.
, vol.83
, Issue.3
, pp. 1015-1031
-
-
Boyles, J.K.1
Zoellner, C.D.2
Anderson, L.J.3
Kosik, L.M.4
Pitas, R.E.5
Weisgraber, K.H.6
Hui, D.Y.7
Mahley, R.W.8
Gebicke-Haerter, P.J.9
Ignatius, M.J.10
-
16
-
-
0028227379
-
Cardiovascular disease and distribution of cognitive function in elderly people: The Rotterdam Study
-
Breteler MM, Claus JJ, Grobbee DE, Hofman A. 1994. Cardiovascular disease and distribution of cognitive function in elderly people: The Rotterdam Study. Br Med J 308(6944):1604-1608.
-
(1994)
Br. Med. J.
, vol.308
, Issue.6944
, pp. 1604-1608
-
-
Breteler, M.M.1
Claus, J.J.2
Grobbee, D.E.3
Hofman, A.4
-
17
-
-
0031695197
-
Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
-
Brookmeyer R, Gray S, Kawas C. 1998. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 88(9):1337-1342.
-
(1998)
Am. J. Public Health
, vol.88
, Issue.9
, pp. 1337-1342
-
-
Brookmeyer, R.1
Gray, S.2
Kawas, C.3
-
18
-
-
0027322448
-
Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease
-
Brown BG, Zhao XQ, Sacco DE, Albers JJ. 1993. Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease. Circulation 87(6):1781-1791.
-
(1993)
Circulation
, vol.87
, Issue.6
, pp. 1781-1791
-
-
Brown, B.G.1
Zhao, X.Q.2
Sacco, D.E.3
Albers, J.J.4
-
19
-
-
0036860349
-
Metal complexing agents as therapies for Alzheimer's disease
-
Bush AI. 2002. Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging 23(6):1031-1038.
-
(2002)
Neurobiol. Aging
, vol.23
, Issue.6
, pp. 1031-1038
-
-
Bush, A.I.1
-
20
-
-
0141483385
-
Copper, zinc, and the metallobiology of Alzheimer disease
-
Bush AI. 2003. Copper, zinc, and the metallobiology of Alzheimer disease. Alzheimer Dis Assoc Disord 17(3):147-150.
-
(2003)
Alzheimer Dis. Assoc. Disord.
, vol.17
, Issue.3
, pp. 147-150
-
-
Bush, A.I.1
-
21
-
-
0028180196
-
Modulation of A beta adhesiveness and secretase site cleavage by zinc
-
Bush AI, Pettingell WH Jr, Paradis MD, Tanzi RE. 1994a. Modulation of A beta adhesiveness and secretase site cleavage by zinc. J Biol Chem 269(16):12152-12158.
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.16
, pp. 12152-12158
-
-
Bush, A.I.1
Pettingell Jr., W.H.2
Paradis, M.D.3
Tanzi, R.E.4
-
22
-
-
0027980901
-
Rapid induction of Alzheimer A beta amyloid formation by zinc
-
Bush AI, Pettingell WH, Multhaup G, Paradis MD, Vonsattel JP, Gusella JF, Beyreuther K, Masters CL, Tanzi RE. 1994b. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science 265(5177):1464-1467.
-
(1994)
Science
, vol.265
, Issue.5177
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
Paradis, M.D.4
Vonsattel, J.P.5
Gusella, J.F.6
Beyreuther, K.7
Masters, C.L.8
Tanzi, R.E.9
-
23
-
-
0242424155
-
Self-assembly of Abeta(1-42) into globular neurotoxins
-
Chromy BA, Nowak RJ, Lambert MP, Viola KL, Chang L, Velasco PT, Jones BW, Fernandez SJ, Lacor PN, Horowitz P, Finch CE, Kraft GA, Klein WL. 2003. Self-assembly of Abeta(1-42) into globular neurotoxins. Biochemistry 42(44):12749-12760.
-
(2003)
Biochemistry
, vol.42
, Issue.44
, pp. 12749-12760
-
-
Chromy, B.A.1
Nowak, R.J.2
Lambert, M.P.3
Viola, K.L.4
Chang, L.5
Velasco, P.T.6
Jones, B.W.7
Fernandez, S.J.8
Lacor, P.N.9
Horowitz, P.10
Finch, C.E.11
Kraft, G.A.12
Klein, W.L.13
-
24
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. 1993. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261(5123):921-923.
-
(1993)
Science
, vol.261
, Issue.5123
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
25
-
-
3042567016
-
Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised double-blind trial
-
Courtney C, Farrell D, Gray R, Hills R, Lynch L, Sellwood E, Edwards S, Hardyman W, Raftery J, Crome P, Lendon C, Shaw H, Bentham P. 2004. Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised double-blind trial. Lancet 363(9427):2105-2115.
-
(2004)
Lancet
, vol.363
, Issue.9427
, pp. 2105-2115
-
-
Courtney, C.1
Farrell, D.2
Gray, R.3
Hills, R.4
Lynch, L.5
Sellwood, E.6
Edwards, S.7
Hardyman, W.8
Raftery, J.9
Crome, P.10
Lendon, C.11
Shaw, H.12
Bentham, P.13
-
26
-
-
0035916233
-
Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
-
Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. 2001. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 103(7):926-933.
-
(2001)
Circulation
, vol.103
, Issue.7
, pp. 926-933
-
-
Crisby, M.1
Nordin-Fredriksson, G.2
Shah, P.K.3
Yano, J.4
Zhu, J.5
Nilsson, J.6
-
27
-
-
0022435132
-
Image reconstruction of the Alzheimer paired helical filament
-
Crowther RA, Wischik CM. 1985. Image reconstruction of the Alzheimer paired helical filament. EMBO J 4(13B):3661-3665.
-
(1985)
EMBO J.
, vol.4
, Issue.13 B
, pp. 3661-3665
-
-
Crowther, R.A.1
Wischik, C.M.2
-
28
-
-
0035875462
-
Use of statins in CNS disorders
-
Cucchiara B, Kasner SE. 2001. Use of statins in CNS disorders. J Neurol Sci 187(1-2):81-89.
-
(2001)
J. Neurol. Sci.
, vol.187
, Issue.1-2
, pp. 81-89
-
-
Cucchiara, B.1
Kasner, S.E.2
-
29
-
-
0033393022
-
Low-density lipoprotein-independent effects of statins
-
Davignon J, Laaksonen R. 1999. Low-density lipoprotein-independent effects of statins. Curr Opin Lipidol 10(6):543-59.
-
(1999)
Curr. Opin. Lipidol.
, vol.10
, Issue.6
, pp. 543-559
-
-
Davignon, J.1
Laaksonen, R.2
-
30
-
-
0036218738
-
Alzheimer disease as a vascular disorder: Nosological evidence
-
de la Torre JC. 2002. Alzheimer disease as a vascular disorder: Nosological evidence. Stroke 33 (4): 1152-1162.
-
(2002)
Stroke
, vol.33
, Issue.4
, pp. 1152-1162
-
-
de la Torre, J.C.1
-
31
-
-
0032556859
-
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
De Strooper B, Saftig P, Craessaerts K, Vanderstichele H, Guhde G, Annaert W, Von Figura K, Van Leuven F. 1998. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 391(6665):387-390.
-
(1998)
Nature
, vol.391
, Issue.6665
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Guhde, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
32
-
-
0035902619
-
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. 2001. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 98(15):8850-8855.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.15
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
33
-
-
0030579742
-
The challenge of the dementias
-
Eastwood R, Amaducci L, Brayne C, Broe T, Burns A, Copeland J, Dickens B, Goate A, Hachinski V, Henderson S, Jolles J, Ritchie MJK, Roses A, Rossor M, Schellenberg G, Skoog I, Storandt M, Tallis R, Whitehouse P, Clark S, Evans I, Horton R, Sharp D. 1996. The challenge of the dementias. Lancet 347:1303-1307.
-
(1996)
Lancet
, vol.347
, pp. 1303-1307
-
-
Eastwood, R.1
Amaducci, L.2
Brayne, C.3
Broe, T.4
Burns, A.5
Copeland, J.6
Dickens, B.7
Goate, A.8
Hachinski, V.9
Henderson, S.10
Jolles, J.11
Ritchie, M.J.K.12
Roses, A.13
Rossor, M.14
Schellenberg, G.15
Skoog, I.16
Storandt, M.17
Tallis, R.18
Whitehouse, P.19
Clark, S.20
Evans, I.21
Horton, R.22
Sharp, D.23
more..
-
34
-
-
0035901715
-
Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice
-
Eckert GP, Kirsch C, Mueller WE. 2001. Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice. Neuroreport 12(5):883-887.
-
(2001)
Neuroreport
, vol.12
, Issue.5
, pp. 883-887
-
-
Eckert, G.P.1
Kirsch, C.2
Mueller, W.E.3
-
35
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer {beta}-amyloid precursor protein depends on lipid rafts
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K. 2003. Amyloidogenic processing of the Alzheimer {beta}-amyloid precursor protein depends on lipid rafts. J Cell Biol 160(1):113-123.
-
(2003)
J. Cell Biol.
, vol.160
, Issue.1
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
36
-
-
0023764870
-
Familial hypercholesterolemia and apolipoprotein E4
-
Eto M, Watanabe K, Chonan N, Ishii K. 1988. Familial hypercholesterolemia and apolipoprotein E4. Atherosclerosis 72(2-3):123-128.
-
(1988)
Atherosclerosis
, vol.72
, Issue.2-3
, pp. 123-128
-
-
Eto, M.1
Watanabe, K.2
Chonan, N.3
Ishii, K.4
-
37
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
-
Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P, Runz H, Kuhl S, Bertsch T, von Bergmann K, Hermerici M, Beyreuther K, Hartmann T. 2001. Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc Natl Acad Sci USA 98(10):5856-5861.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.10
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
Runz, H.7
Kuhl, S.8
Bertsch, T.9
von Bergmann, K.10
Hermerici, M.11
Beyreuther, K.12
Hartmann, T.13
-
38
-
-
0141960033
-
Beta-Amyloid induces paired helical filament-like tau filaments in tissue culture
-
Ferrari A, Hoerndli F, Baechi T, Nitsch RM, Gotz J. 2003. beta-Amyloid induces paired helical filament-like tau filaments in tissue culture. J Biol Chem 278(41):40162-40168.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.41
, pp. 40162-40168
-
-
Ferrari, A.1
Hoerndli, F.2
Baechi, T.3
Nitsch, R.M.4
Gotz, J.5
-
39
-
-
0042021925
-
Current status of metals as therapeutic targets in Alzheimer's disease
-
Finefrock AE, Bush AI, Doraiswamy PM. 2003. Current status of metals as therapeutic targets in Alzheimer's disease. J Am Geriatr Soc 51(8):1143-1148.
-
(2003)
J. Am. Geriatr. Soc.
, vol.51
, Issue.8
, pp. 1143-1148
-
-
Finefrock, A.E.1
Bush, A.I.2
Doraiswamy, P.M.3
-
40
-
-
0033519601
-
The role of cholesterol in the biosynthesis of beta-amyloid
-
Frears ER, Stephens DJ, Walters CE, Davies H, Austen BM. 1999. The role of cholesterol in the biosynthesis of beta-amyloid. Neuroreport 10(8):1699-1705.
-
(1999)
Neuroreport
, vol.10
, Issue.8
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
41
-
-
0024779411
-
Neurobiology of zinc and zinc-containing neurons
-
Frederickson CJ. 1989. Neurobiology of zinc and zinc-containing neurons. Int Rev Neurobiol 31:145-238.
-
(1989)
Int. Rev. Neurobiol.
, vol.31
, pp. 145-238
-
-
Frederickson, C.J.1
-
42
-
-
0034956750
-
Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide
-
Friedhoff LT, Cullen EI, Geoghagen NS, Buxbaum JD. 2001. Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide. Int J Neuropsychopharmacol 4(2):127-130.
-
(2001)
Int. J. Neuropsychopharmacol.
, vol.4
, Issue.2
, pp. 127-130
-
-
Friedhoff, L.T.1
Cullen, E.I.2
Geoghagen, N.S.3
Buxbaum, J.D.4
-
43
-
-
2342536907
-
Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: Potential relevance to atherosclerotic plaque stability
-
Furman C, Copin C, Kandoussi M, Davidson R, Moreau M, McTaggiart F, Chapman MJ, Fruchart JC, Rouis M. 2004. Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: Potential relevance to atherosclerotic plaque stability. Atherosclerosis 174(1):93-98.
-
(2004)
Atherosclerosis
, vol.174
, Issue.1
, pp. 93-98
-
-
Furman, C.1
Copin, C.2
Kandoussi, M.3
Davidson, R.4
Moreau, M.5
McTaggiart, F.6
Chapman, M.J.7
Fruchart, J.C.8
Rouis, M.9
-
44
-
-
0034214328
-
Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway
-
Galbete JL, Martin TR, Peressini E, Modena P, Bianchi R, Forloni G. 2000. Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway. Biochem J 348(Pt 2):307-313.
-
(2000)
Biochem. J.
, vol.348
, Issue.PART 2
, pp. 307-313
-
-
Galbete, J.L.1
Martin, T.R.2
Peressini, E.3
Modena, P.4
Bianchi, R.5
Forloni, G.6
-
45
-
-
18844479720
-
Heritability for Alzheimer's disease: The study of dementia in Swedish twins
-
Gatz M, Pedersen NL, Berg S, Johansson B, Johansson K, Mortimer JA, Posner SF, Viitanen M, Winblad B, Ahlbom A. 1997. Heritability for Alzheimer's disease: The study of dementia in Swedish twins. J Gerontol A Biol Sci Med Sci 52(2):M117-125.
-
(1997)
J. Gerontol. A. Biol. Sci. Med. Sci.
, vol.52
, Issue.2
-
-
Gatz, M.1
Pedersen, N.L.2
Berg, S.3
Johansson, B.4
Johansson, K.5
Mortimer, J.A.6
Posner, S.F.7
Viitanen, M.8
Winblad, B.9
Ahlbom, A.10
-
46
-
-
0031824782
-
Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity
-
Geula C, Wu CK, Saroff D, Lorenzo A, Yuan M, Yankner BA. 1998. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity. Nat Med 4(7):827-831.
-
(1998)
Nat. Med.
, vol.4
, Issue.7
, pp. 827-831
-
-
Geula, C.1
Wu, C.K.2
Saroff, D.3
Lorenzo, A.4
Yuan, M.5
Yankner, B.A.6
-
47
-
-
0027420369
-
Tau protein and the neurofibrillary pathology of Alzheimer's disease
-
Goedert M. 1993. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends Neurosci 16(11):460-465.
-
(1993)
Trends Neurosci.
, vol.16
, Issue.11
, pp. 460-465
-
-
Goedert, M.1
-
48
-
-
0002792366
-
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
-
Goedert M, Wischik CM, Crowther RA, Walker JE, Klug A. 1988. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau. Proc Natl Acad Sci USA 85(11):4051-4055.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, Issue.11
, pp. 4051-4055
-
-
Goedert, M.1
Wischik, C.M.2
Crowther, R.A.3
Walker, J.E.4
Klug, A.5
-
49
-
-
0035943436
-
Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Abeta 42 fibrils
-
Gotz J, Chen F, van Dorpe J, Nitsch RM. 2001. Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Abeta 42 fibrils. Science 293(5534):1491-1495.
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
van Dorpe, J.3
Nitsch, R.M.4
-
50
-
-
0025740733
-
Alcohol and tobacco consumption as risk factors for Alzheimer's disease: A collaborative re-analysis of case-control studies
-
EURODEM Risk Factors Research Group
-
Graves AB, van Duijn CM, Chandra V, Fratiglioni L, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Rocca WA, et al. 1991. Alcohol and tobacco consumption as risk factors for Alzheimer's disease: A collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group. Int J Epidemiol 20(Suppl 2):S48-57.
-
(1991)
Int. J. Epidemiol.
, vol.20
, Issue.SUPPL. 2
-
-
Graves, A.B.1
van Duijn, C.M.2
Chandra, V.3
Fratiglioni, L.4
Heyman, A.5
Jorm, A.F.6
Kokmen, E.7
Kondo, K.8
Mortimer, J.A.9
Rocca, W.A.10
-
51
-
-
0027333557
-
Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide
-
Haass C, Selkoe DJ. 1993. Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell 75(6):1039-1042.
-
(1993)
Cell
, vol.75
, Issue.6
, pp. 1039-1042
-
-
Haass, C.1
Selkoe, D.J.2
-
52
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J, Allsop D. 1991. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 12:383-388.
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
53
-
-
0028298389
-
Apolipoprotein E and cholesterol affect neuronal calcium signalling: The possible relationship to beta-amyloid neurotoxicity
-
Hartmann H, Eckert A, Muller WE. 1994. Apolipoprotein E and cholesterol affect neuronal calcium signalling: The possible relationship to beta-amyloid neurotoxicity. Biochem Biophys Res Commun 200(3):1185-1192.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.200
, Issue.3
, pp. 1185-1192
-
-
Hartmann, H.1
Eckert, A.2
Muller, W.E.3
-
54
-
-
0023616195
-
Low density lipoprotein receptor regulation and the cellular basis of atherosclerosis: Implications for nutritional and pharmacologic treatment of hypercholesterolemia
-
Heber D, Koziol BJ, Henson LC. 1987. Low density lipoprotein receptor regulation and the cellular basis of atherosclerosis: Implications for nutritional and pharmacologic treatment of hypercholesterolemia. Am J Cardiol 60(12):4-8G.
-
(1987)
Am. J. Cardiol.
, vol.60
, Issue.12
-
-
Heber, D.1
Koziol, B.J.2
Henson, L.C.3
-
55
-
-
0030802435
-
Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials
-
Hebert PR, Gaziano JM, Chan KS, Hennekens CH. 1997. Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. J Am Med Assoc 278(4):313-321.
-
(1997)
J. Am. Med. Assoc.
, vol.278
, Issue.4
, pp. 313-321
-
-
Hebert, P.R.1
Gaziano, J.M.2
Chan, K.S.3
Hennekens, C.H.4
-
56
-
-
0346736491
-
Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
-
Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, Sanchez-Pascuala R, Hernandez G, Diaz C, Lamas S. 1998. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J Clin Invest 101(12):2711-2719.
-
(1998)
J. Clin. Invest.
, vol.101
, Issue.12
, pp. 2711-2719
-
-
Hernandez-Perera, O.1
Perez-Sala, D.2
Navarro-Antolin, J.3
Sanchez-Pascuala, R.4
Hernandez, G.5
Diaz, C.6
Lamas, S.7
-
57
-
-
0034730781
-
Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells
-
Hernandez-Perera O, Perez-Sala D, Soria E, Lamas S. 2000. Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells. Circ Res 87(7):616-622.
-
(2000)
Circ. Res.
, vol.87
, Issue.7
, pp. 616-622
-
-
Hernandez-Perera, O.1
Perez-Sala, D.2
Soria, E.3
Lamas, S.4
-
58
-
-
0031026879
-
Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study
-
Hofman A, Ott A, Breteler MM, Bots MI, Slooter AJ, van Harskamp F, van Duijn CN, Van Broeckhoven C, Grobbee DE. 1997. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet 349(9046):151-154.
-
(1997)
Lancet
, vol.349
, Issue.9046
, pp. 151-154
-
-
Hofman, A.1
Ott, A.2
Breteler, M.M.3
Bots, M.I.4
Slooter, A.J.5
van Harskamp, F.6
van Duijn, C.N.7
Van Broeckhoven, C.8
Grobbee, D.E.9
-
59
-
-
4243215848
-
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
-
Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. 2000. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 97(6):2892-2897.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, Issue.6
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
Mackey, B.7
Olney, J.8
McKeel, D.9
Wozniak, D.10
Paul, S.M.11
-
60
-
-
0032568843
-
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol
-
Howland DS, Trusko SP, Savage MJ, Reaume AG, Lang DM, Hirsch JD, Maeda N, Siman R, Greenberg BD, Scott RW, Flood DG. 1998. Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J Biol Chem 273(26):16576-16582.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.26
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maeda, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
61
-
-
0034638746
-
2000 Statins and the risk of dementia
-
Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA. 2000. Statins and the risk of dementia. Lancet 356(9242):1627-1631.
-
Lancet
, vol.356
, Issue.9242
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
62
-
-
0037028782
-
Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: A randomized controlled trial
-
Jula A, Marniemi J, Huupponen R, Virtanen A, Pastas M, Ronnemaa T. 2002. Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: A randomized controlled trial. J Am Med Assoc 287(5):598-605.
-
(2002)
J. Am. Med. Assoc.
, vol.287
, Issue.5
, pp. 598-605
-
-
Jula, A.1
Marniemi, J.2
Huupponen, R.3
Virtanen, A.4
Pastas, M.5
Ronnemaa, T.6
-
63
-
-
0034980106
-
Intracellular calcium changes in neuronal cells induced by Alzheimer's beta-amyloid protein are blocked by estradiol and cholesterol
-
Kawahara M, Kuroda Y. 2001. Intracellular calcium changes in neuronal cells induced by Alzheimer's beta-amyloid protein are blocked by estradiol and cholesterol. Cell Mol Neurobiol 21(1):1-13.
-
(2001)
Cell Mol. Neurobiol.
, vol.21
, Issue.1
, pp. 1-13
-
-
Kawahara, M.1
Kuroda, Y.2
-
64
-
-
37049048544
-
Paired helical filaments in electron microscopy of Alzheimer's disease
-
Kidd M. 1963. Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 197:192-193.
-
(1963)
Nature
, vol.197
, pp. 192-193
-
-
Kidd, M.1
-
65
-
-
0029120852
-
Cellular cholesterol efflux mediated by cyclodextrins
-
Kilsdonk EP, Yancey PG, Stoudt GW, Bangerter FW, Johnson WJ, Phillips MC, Rothblat GH. 1995. Cellular cholesterol efflux mediated by cyclodextrins. J Biol Chem 270(29):17250-17256.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.29
, pp. 17250-17256
-
-
Kilsdonk, E.P.1
Yancey, P.G.2
Stoudt, G.W.3
Bangerter, F.W.4
Johnson, W.J.5
Phillips, M.C.6
Rothblat, G.H.7
-
66
-
-
0035897938
-
Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
-
Kivipelto M, Helkala EL, Laakso MP, Hanninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A. 2001. Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study. Br Med J 322(7300):1447-1451.
-
(2001)
Br. Med. J.
, vol.322
, Issue.7300
, pp. 1447-1451
-
-
Kivipelto, M.1
Helkala, E.L.2
Laakso, M.P.3
Hanninen, T.4
Hallikainen, M.5
Alhainen, K.6
Soininen, H.7
Tuomilehto, J.8
Nissinen, A.9
-
67
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10
-
Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F. 2001. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10. Proc Natl Acad Sci USA 98(10):5815-5820.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.10
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
68
-
-
0036384169
-
Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease
-
Kolsch H, Lutjohann D, Ludwig M, Schulte A, Ptok U, Jessen F, von Bergmann K, Rao ME, Maier W, Heun R. 2002. Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease. Mol Psychiatry 7(8):899-902.
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.8
, pp. 899-902
-
-
Kolsch, H.1
Lutjohann, D.2
Ludwig, M.3
Schulte, A.4
Ptok, U.5
Jessen, F.6
von Bergmann, K.7
Rao, M.E.8
Maier, W.9
Heun, R.10
-
69
-
-
0028176821
-
Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
-
Kurochkin IV, Goto S. 1994. Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett 345(1):33-37.
-
(1994)
FEBS Lett.
, vol.345
, Issue.1
, pp. 33-37
-
-
Kurochkin, I.V.1
Goto, S.2
-
70
-
-
0037465360
-
Reduced connexin3 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice
-
Kwak BR, Veillard N, Pelli G, Mulhaupt F, James RW, Chanson M, Mach F. 2003. Reduced connexin3 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice. Circulation 107(7):1033-1039.
-
(2003)
Circulation
, vol.107
, Issue.7
, pp. 1033-1039
-
-
Kwak, B.R.1
Veillard, N.2
Pelli, G.3
Mulhaupt, F.4
James, R.W.5
Chanson, M.6
Mach, F.7
-
71
-
-
0033800718
-
Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice
-
Laufs U, Gertz K, Huang P, Nickenig G, Bohm M, Dirnagl U, Endres M. 2000. Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice. Stroke 31(10):2442-2449.
-
(2000)
Stroke
, vol.31
, Issue.10
, pp. 2442-2449
-
-
Laufs, U.1
Gertz, K.2
Huang, P.3
Nickenig, G.4
Bohm, M.5
Dirnagl, U.6
Endres, M.7
-
72
-
-
0030953045
-
Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences
-
Lennernas H, Fager G. 1997. Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clin Pharmacokinet 32(5):403-425.
-
(1997)
Clin. Pharmacokinet.
, vol.32
, Issue.5
, pp. 403-425
-
-
Lennernas, H.1
Fager, G.2
-
73
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K, et al. 1995. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269(5226):973-977.
-
(1995)
Science
, vol.269
, Issue.5226
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
-
74
-
-
0343819757
-
Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state
-
Li YM, Lai MT, Xu M, Huang Q, DiMuzio-Mower J, Sardana MK, Shi XP, Yin KC, Sharer JA, Gardell SJ. 2000. Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state. Proc Natl Acad Sci USA 97(11):6138-6143.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, Issue.11
, pp. 6138-6143
-
-
Li, Y.M.1
Lai, M.T.2
Xu, M.3
Huang, Q.4
DiMuzio-Mower, J.5
Sardana, M.K.6
Shi, X.P.7
Yin, K.C.8
Sharer, J.A.9
Gardell, S.J.10
-
75
-
-
0036128358
-
Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: Evidence that simvastatin affects cholesterol metabolism in the human brain
-
Locatelli S, Lutjohann D, Schmidt HH, Otto C, Beisiegel U, von Bergmann K. 2002. Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: Evidence that simvastatin affects cholesterol metabolism in the human brain. Arch Neurol 59(2):213-216.
-
(2002)
Arch. Neurol.
, vol.59
, Issue.2
, pp. 213-216
-
-
Locatelli, S.1
Lutjohann, D.2
Schmidt, H.H.3
Otto, C.4
Beisiegel, U.5
von Bergmann, K.6
-
76
-
-
0030963565
-
Reduced levels of antioxidants in brains of apolipoprotein E-defcient mice following closed head injury
-
Lomnitski L, Kohen R, Chen Y, Shohami E, Trembovler V, Vogel T, Michaelson DM. 1997. Reduced levels of antioxidants in brains of apolipoprotein E-defcient mice following closed head injury. Pharmacol Biochem Behav 56(4):669-673.
-
(1997)
Pharmacol. Biochem. Behav.
, vol.56
, Issue.4
, pp. 669-673
-
-
Lomnitski, L.1
Kohen, R.2
Chen, Y.3
Shohami, E.4
Trembovler, V.5
Vogel, T.6
Michaelson, D.M.7
-
77
-
-
0343775806
-
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients
-
Lutjohann D, Papassotiropoulos A, Bjorkhem I, Locatelli S, Bagli M, Oehring RD, Schlegel U, Jessen F, Rao ML, von Bergmann K, Heun R. 2000. Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res 41(2):195-198.
-
(2000)
J. Lipid Res.
, vol.41
, Issue.2
, pp. 195-198
-
-
Lutjohann, D.1
Papassotiropoulos, A.2
Bjorkhem, I.3
Locatelli, S.4
Bagli, M.5
Oehring, R.D.6
Schlegel, U.7
Jessen, F.8
Rao, M.L.9
von Bergmann, K.10
Heun, R.11
-
78
-
-
0033984436
-
Current perspectives on statins
-
Maron DJ, Fazio S, Linton MF. 2000. Current perspectives on statins. Circulation 101(2):207-213.
-
(2000)
Circulation
, vol.101
, Issue.2
, pp. 207-213
-
-
Maron, D.J.1
Fazio, S.2
Linton, M.F.3
-
79
-
-
0033968648
-
Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
-
Michikawa M, Fan QW, Isobe I, Yanagisawa K. 2000. Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 74(3):1008-1016.
-
(2000)
J. Neurochem.
, vol.74
, Issue.3
, pp. 1008-1016
-
-
Michikawa, M.1
Fan, Q.W.2
Isobe, I.3
Yanagisawa, K.4
-
80
-
-
0141452104
-
Reduction in serum levels of adhesion molecules, interleukin-6 and C-reactive protein following short-term low-dose atorvastatin treatment in patients with non-familial hypercholesterolemia
-
Nawawi H, Osman NS, Yusoff K, Khalid BA. 2003. Reduction in serum levels of adhesion molecules, interleukin-6 and C-reactive protein following short-term low-dose atorvastatin treatment in patients with non-familial hypercholesterolemia. Horm Metab Res 35(8):479-485.
-
(2003)
Horm. Metab. Res.
, vol.35
, Issue.8
, pp. 479-485
-
-
Nawawi, H.1
Osman, N.S.2
Yusoff, K.3
Khalid, B.A.4
-
81
-
-
0031976318
-
Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease
-
Notkola IL, Sulkava R, Pekkanen J, Erkinjuntti T, Ehnholm C, Kivinen P, Tuomilehto J, Nissinen A. 1998. Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease. Neuroepidemiology 17(1):14-20.
-
(1998)
Neuroepidemiology
, vol.17
, Issue.1
, pp. 14-20
-
-
Notkola, I.L.1
Sulkava, R.2
Pekkanen, J.3
Erkinjuntti, T.4
Ehnholm, C.5
Kivinen, P.6
Tuomilehto, J.7
Nissinen, A.8
-
82
-
-
0029450271
-
The amyloid peptide precursor in Alzheimer's disease
-
Octave JN. 1995. The amyloid peptide precursor in Alzheimer's disease. Acta Neurol Belg 95(4):197-209.
-
(1995)
Acta Neurol. Belg.
, vol.95
, Issue.4
, pp. 197-209
-
-
Octave, J.N.1
-
83
-
-
0030977937
-
Wine consumption and dementia in the elderly: A prospective community study in the Bordeaux area
-
Orgogozo JM, Dartigues JF, Lafont S, Letenneur L, Commenges D, Salamon R, Renaud S, Breteler MB. 1997. Wine consumption and dementia in the elderly: A prospective community study in the Bordeaux area. Rev Neurol (Paris) 153(3):185-192.
-
(1997)
Rev. Neurol. (Paris)
, vol.153
, Issue.3
, pp. 185-192
-
-
Orgogozo, J.M.1
Dartigues, J.F.2
Lafont, S.3
Letenneur, L.4
Commenges, D.5
Salamon, R.6
Renaud, S.7
Breteler, M.B.8
-
84
-
-
0029966901
-
Association of diabetes mellitus and dementia: The Rotterdam Study
-
Ott A, Stolk RP, Hofman A, van Harskamp F, Grobbee DE, Breteler MM.. 1996. Association of diabetes mellitus and dementia: the Rotterdam Study. Diabetologia 39(11):1392-1397.
-
(1996)
Diabetologia
, vol.39
, Issue.11
, pp. 1392-1397
-
-
Ott, A.1
Stolk, R.P.2
Hofman, A.3
van Harskamp, F.4
Grobbee, D.E.5
Breteler, M.M.6
-
85
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A, Stolk RP, van Harskamp F, Pols HA, Hofman A, Breteler MM. 1999. Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 53(9):1937-1942.
-
(1999)
Neurology
, vol.53
, Issue.9
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
van Harskamp, F.3
Pols, H.A.4
Hofman, A.5
Breteler, M.M.6
-
86
-
-
0036138648
-
24S-Hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia
-
Papassotiropoulos A, Lutjohann D, Bagli M, Locatelli S, Jessen F, Buschfort R, Ptok U, Bjorkhem I, von Bergmann K, Heun R. 2002. 24S-Hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. J Psychiatr Res 36(1):27-32.
-
(2002)
J. Psychiatr. Res.
, vol.36
, Issue.1
, pp. 27-32
-
-
Papassotiropoulos, A.1
Lutjohann, D.2
Bagli, M.3
Locatelli, S.4
Jessen, F.5
Buschfort, R.6
Ptok, U.7
Bjorkhem, I.8
von Bergmann, K.9
Heun, R.10
-
87
-
-
0037227538
-
Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism
-
Papassotiropoulos A, Streffer JR, Tsolaki M, Schmid S, Thal D, Nicosia F, Iakovidou V, Maddalena A, Lutjohann D, Ghebremedhin E, Hegi T, Pasch T, Traxler M, Bruhl A, Benussi L, Binetti G, Braak H, Nitsch RM, Hock C. 2003. Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Arch Neurol 60(1):29-35.
-
(2003)
Arch. Neurol.
, vol.60
, Issue.1
, pp. 29-35
-
-
Papassotiropoulos, A.1
Streffer, J.R.2
Tsolaki, M.3
Schmid, S.4
Thal, D.5
Nicosia, F.6
Iakovidou, V.7
Maddalena, A.8
Lutjohann, D.9
Ghebremedhin, E.10
Hegi, T.11
Pasch, T.12
Traxler, M.13
Bruhl, A.14
Benussi, L.15
Binetti, G.16
Braak, H.17
Nitsch, R.M.18
Hock, C.19
-
88
-
-
11444256434
-
Apolipoprotein E: A Novel therapeutic target for the treatment of Alzheimer's disease
-
Poirier J, Panisset M. 2002. Apolipoprotein E: A Novel therapeutic target for the treatment of Alzheimer's disease. Adv Behav Biol 1:36-42.
-
(2002)
Adv. Behav. Biol.
, vol.1
, pp. 36-42
-
-
Poirier, J.1
Panisset, M.2
-
89
-
-
2542454942
-
Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex
-
Prokop S, Shirotani K, Edbauer D, Haass C, Steiner H. 2004. Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex. J Biol Chem 279(22):23255-23261.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.22
, pp. 23255-23261
-
-
Prokop, S.1
Shirotani, K.2
Edbauer, D.3
Haass, C.4
Steiner, H.5
-
90
-
-
0034795651
-
Acyl-coenzyme A:cholesterol acyltransferase modulates the generation of the amyloid beta-peptide
-
Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. 2001. Acyl-coenzyme A:cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol 3(10):905-912.
-
(2001)
Nat. Cell Biol.
, vol.3
, Issue.10
, pp. 905-912
-
-
Puglielli, L.1
Konopka, G.2
Pack-Chung, E.3
Ingano, L.A.4
Berezovska, O.5
Hyman, B.T.6
Chang, T.Y.7
Tanzi, R.E.8
Kovacs, D.M.9
-
91
-
-
17644429206
-
Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content
-
Racchi M, Baetta R, Salvietti N, Ianna P, Franceschini G, Paoletti R, Fumagalli R, Govoni S, Trabucchi M, Soma M. 1997. Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content. Biochem J 322(Pt 3):893-898.
-
(1997)
Biochem. J.
, vol.322
, Issue.PART 3
, pp. 893-898
-
-
Racchi, M.1
Baetta, R.2
Salvietti, N.3
Ianna, P.4
Franceschini, G.5
Paoletti, R.6
Fumagalli, R.7
Govoni, S.8
Trabucchi, M.9
Soma, M.10
-
92
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA. 2000. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7(4):321-331.
-
(2000)
Neurobiol. Dis.
, vol.7
, Issue.4
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
LaFrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
Sambamurti, K.7
Duff, K.8
Pappolla, M.A.9
-
93
-
-
0035160066
-
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease
-
Refolo LM, Pappolla MA, LaFrancois J, Malester B, Schmidt SD, Thomas-Bryant T, Tint GS, Wang R, Mercken M, Petanceska SS, Duff KE. 2001. A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis 8(5):890-899.
-
(2001)
Neurobiol. Dis.
, vol.8
, Issue.5
, pp. 890-899
-
-
Refolo, L.M.1
Pappolla, M.A.2
LaFrancois, J.3
Malester, B.4
Schmidt, S.D.5
Thomas-Bryant, T.6
Tint, G.S.7
Wang, R.8
Mercken, M.9
Petanceska, S.S.10
Duff, K.E.11
-
94
-
-
18444399243
-
Treatment of Alzheimer's disease with clioquinol
-
Regland B, Lehmann W, Abedini I, Blennow K, Jonsson M, Karlsson I, Sjogren M, Wallin A, Xilinas M, Gotffries CG. 2001. Treatment of Alzheimer's disease with clioquinol. Dement Geriatr Cogn Disord 12(6):408-414.
-
(2001)
Dement. Geriatr. Cogn. Disord.
, vol.12
, Issue.6
, pp. 408-414
-
-
Regland, B.1
Lehmann, W.2
Abedini, I.3
Blennow, K.4
Jonsson, M.5
Karlsson, I.6
Sjogren, M.7
Wallin, A.8
Xilinas, M.9
Gotffries, C.G.10
-
95
-
-
0035853154
-
Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease
-
Reiman EM, Caselli RJ, Chen K, Alexander GE, Bandy D, Frost J. 2001. Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci USA 98(6):3334-3339.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.6
, pp. 3334-3339
-
-
Reiman, E.M.1
Caselli, R.J.2
Chen, K.3
Alexander, G.E.4
Bandy, D.5
Frost, J.6
-
96
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, Davis S, Beyreuther K, Tanzi RE, Masters CL. 2003. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial. Arch Neurol 60(12):1685-1691.
-
(2003)
Arch. Neurol.
, vol.60
, Issue.12
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
Macfarlane, S.4
Mastwyk, M.5
MacGregor, L.6
Kiers, L.7
Cherny, R.8
Li, Q.X.9
Tammer, A.10
Carrington, D.11
Mavros, C.12
Volitakis, I.13
Xilinas, M.14
Ames, D.15
Davis, S.16
Beyreuther, K.17
Tanzi, R.E.18
Masters, C.L.19
-
97
-
-
0038240721
-
Causative and susceptibility genes for Alzheimer's disease: A review
-
Rocchi A, Pellegrini S, Siciliano G, Murri L. 2003. Causative and susceptibility genes for Alzheimer's disease: A review. Brain Res Bull 61(1):1-24.
-
(2003)
Brain Res. Bull.
, vol.61
, Issue.1
, pp. 1-24
-
-
Rocchi, A.1
Pellegrini, S.2
Siciliano, G.3
Murri, L.4
-
98
-
-
0036126850
-
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people
-
Rockwood K, Kirkland S, Hogan DB, MacKnight C, Merry H, Verreault R, Wolfson C, McDowell I.. 2002. Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people. Arch Neurol 59(2):223-7.
-
(2002)
Arch. Neurol.
, vol.59
, Issue.2
, pp. 223-227
-
-
Rockwood, K.1
Kirkland, S.2
Hogan, D.B.3
MacKnight, C.4
Merry, H.5
Verreault, R.6
Wolfson, C.7
McDowell, I.8
-
99
-
-
0034643888
-
The molecular and genetic basis of AD: The end of the beginning: The 2000 Wartenberg Lecture
-
Rosenberg RN. 2000. The molecular and genetic basis of AD: The end of the beginning: The 2000 Wartenberg Lecture. Neurology 54(11):2045-2054.
-
(2000)
Neurology
, vol.54
, Issue.11
, pp. 2045-2054
-
-
Rosenberg, R.N.1
-
100
-
-
0035081589
-
Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: Structure and function in atherosclerosis
-
Rudel LL, Lee RG, Cockman TL. 2001. Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr Opin Lipidol 12(2):121-127.
-
(2001)
Curr. Opin. Lipidol.
, vol.12
, Issue.2
, pp. 121-127
-
-
Rudel, L.L.1
Lee, R.G.2
Cockman, T.L.3
-
101
-
-
0036523031
-
Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells
-
Runz H, Rietdorf J, Tomic I, de Bernard M, Beyreuther K, Pepperkok R, Hartmann T. 2002. Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J Neurosci 22(5):1679-1689.
-
(2002)
J. Neurosci.
, vol.22
, Issue.5
, pp. 1679-1689
-
-
Runz, H.1
Rietdorf, J.2
Tomic, I.3
de Bernard, M.4
Beyreuther, K.5
Pepperkok, R.6
Hartmann, T.7
-
102
-
-
0035954426
-
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
-
Sabo SL, Ikin AF, Buxbaum JD, Greengard P. 2001. The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. J Cell Biol 153(7):1403-1414.
-
(2001)
J. Cell Biol.
, vol.153
, Issue.7
, pp. 1403-1414
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
103
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease
-
Sano M, Ernesto C, Thomas R, Klanber M, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman C, Pfeiffer E, Schneider L, Thal L. 1997. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. New Engl J Med 336:1216-1222.
-
(1997)
New Engl. J. Med.
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.3
Klanber, M.4
Schafer, K.5
Grundman, M.6
Woodbury, P.7
Growdon, J.8
Cotman, C.9
Pfeiffer, E.10
Schneider, L.11
Thal, L.12
-
104
-
-
0025675999
-
Familial hypercholesterolemia: Dissection of a receptor disease
-
Schneider WJ. 1990. Familial hypercholesterolemia: Dissection of a receptor disease. Z Kardiol 79(Suppl 3):3-7.
-
(1990)
Z. Kardiol.
, vol.79
, Issue.SUPPL. 3
, pp. 3-7
-
-
Schneider, W.J.1
-
105
-
-
0037052771
-
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls
-
Schonknecht P, Lutjohann D, Pantel J, Bardenheuer H, Hartmann T, von Bergmann K, Beyreuther K, Schroder J. 2002.
-
(2002)
Neurosci. Lett.
, vol.324
, Issue.1
, pp. 83-85
-
-
Schonknecht, P.1
Lutjohann, D.2
Pantel, J.3
Bardenheuer, H.4
Hartmann, T.5
von Bergmann, K.6
Beyreuther, K.7
Schroder, J.8
-
107
-
-
0034516988
-
Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein
-
Selkoe DJ. 2000. Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Ann NY Acad Sci 924:17-25.
-
(2000)
Ann. NY Acad. Sci.
, vol.924
, pp. 17-25
-
-
Selkoe, D.J.1
-
108
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, et al. 1995. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375(6534):754-760.
-
(1995)
Nature
, vol.375
, Issue.6534
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
-
109
-
-
0034529050
-
How cells handle cholesterol
-
Simons K, Ikonen E. 2000. How cells handle cholesterol. Science 290(5497):1721-1726.
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1721-1726
-
-
Simons, K.1
Ikonen, E.2
-
110
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. 1998. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc Natl Acad Sci USA 95(11):6460-6464.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
111
-
-
0036714243
-
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial
-
Simons M, Schwarzler F, Lutjohann D, von Bergmann K, Beyreuther K, Dichgans I, Wormstall H, Hartmann T, Schulz JB. 2002. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. Ann Neurol 52(3):346-350.
-
(2002)
Ann. Neurol.
, vol.52
, Issue.3
, pp. 346-350
-
-
Simons, M.1
Schwarzler, F.2
Lutjohann, D.3
von Bergmann, K.4
Beyreuther, K.5
Dichgans, I.6
Wormstall, H.7
Hartmann, T.8
Schulz, J.B.9
-
112
-
-
0021824223
-
Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation
-
Sing CF, Davignon J. 1985. Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet 37(2):268-285.
-
(1985)
Am. J. Hum. Genet.
, vol.37
, Issue.2
, pp. 268-285
-
-
Sing, C.F.1
Davignon, J.2
-
113
-
-
0037262480
-
Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved APP
-
Sjogren M, Gustafsson K, Syversen S, Olsson A, Edman A, Davidsson P, Wallin A, Blennow K. 2003. Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved APP. Dementia Geriatr Cogn Dis 16(1):25-30.
-
(2003)
Dementia Geriatr. Cogn. Dis.
, vol.16
, Issue.1
, pp. 25-30
-
-
Sjogren, M.1
Gustafsson, K.2
Syversen, S.3
Olsson, A.4
Edman, A.5
Davidsson, P.6
Wallin, A.7
Blennow, K.8
-
114
-
-
0031569486
-
Elevated blood pressure and Alzheimer's disease
-
16, 21
-
Skoog I. 1997. Elevated blood pressure and Alzheimer's disease. Hosp Pract(Off Ed) 32(4):13-14, 16, 21.
-
(1997)
Hosp. Pract. (Off. Ed.)
, vol.32
, Issue.4
, pp. 13-14
-
-
Skoog, I.1
-
115
-
-
0002723163
-
The interaction between vascular disorders and Alzheimer's disease
-
Wisniewski H, editor. Chichester: John Wiley & Sons Ltd
-
Skoog I. 1999. The interaction between vascular disorders and Alzheimer's disease. In: Wisniewski H, editor. Alzheimer's disease and related disorders: Etiology, Pathogenesis and therapeutics. Chichester: John Wiley & Sons Ltd. p 523-530.
-
(1999)
Alzheimer's Disease and Related Disorders: Etiology, Pathogenesis and Therapeutics
, pp. 523-530
-
-
Skoog, I.1
-
117
-
-
0029886238
-
High blood pressure and dementia
-
Skoog I, Lernfelt B, Landahl S. 1996a. High blood pressure and dementia. Lancet 348:65-66.
-
(1996)
Lancet
, vol.348
, pp. 65-66
-
-
Skoog, I.1
Lernfelt, B.2
Landahl, S.3
-
118
-
-
0030003819
-
15-year longitudinal study of blood pressure and dementia
-
Skoog I, Lernfelt B, Landahl S, Palmertz B, Andreasson LA, Nilsson L, Persson G, Oden A, Svanborg A. 1996b. 15-year longitudinal study of blood pressure and dementia. Lancet 347(9009):1141-1145.
-
(1996)
Lancet
, vol.347
, Issue.9009
, pp. 1141-1145
-
-
Skoog, I.1
Lernfelt, B.2
Landahl, S.3
Palmertz, B.4
Andreasson, L.A.5
Nilsson, L.6
Persson, G.7
Oden, A.8
Svanborg, A.9
-
120
-
-
0034643749
-
Is APOE-epsilon4 a risk factor for cognitive impairment in normal aging?
-
Small BJ, Graves AB, McEvoy CL, Crawford FC, Mullan M, Mortimer JA. 2000. Is APOE-epsilon4 a risk factor for cognitive impairment in normal aging? Neurology 54(11):2082-2088.
-
(2000)
Neurology
, vol.54
, Issue.11
, pp. 2082-2088
-
-
Small, B.J.1
Graves, A.B.2
McEvoy, C.L.3
Crawford, F.C.4
Mullan, M.5
Mortimer, J.A.6
-
121
-
-
0028213567
-
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
-
Small DH, Nurcombe V, Reed G, Clarris H, Moir R, Beyreuther K, Masters CL. 1994. A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. J Neurosci 14(4):2117-2127.
-
(1994)
J. Neurosci.
, vol.14
, Issue.4
, pp. 2117-2127
-
-
Small, D.H.1
Nurcombe, V.2
Reed, G.3
Clarris, H.4
Moir, R.5
Beyreuther, K.6
Masters, C.L.7
-
122
-
-
0031911493
-
Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects
-
Smith GE, Bohac DL, Waring SC, Kokmen E, Tangalos EG, Ivnik RJ, Petersen RC. 1998. Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects. Neurology 50(2):355-362.
-
(1998)
Neurology
, vol.50
, Issue.2
, pp. 355-362
-
-
Smith, G.E.1
Bohac, D.L.2
Waring, S.C.3
Kokmen, E.4
Tangalos, E.G.5
Ivnik, R.J.6
Petersen, R.C.7
-
123
-
-
9844226208
-
Coronary artery disease, hypertension, ApoE, and cholesterol: A link to Alzheimer's disease?
-
Sparks DL. 1997. Coronary artery disease, hypertension, ApoE, and cholesterol: A link to Alzheimer's disease? Ann NY Acad Sci 826:128-146.
-
(1997)
Ann. NY Acad. Sci.
, vol.826
, pp. 128-146
-
-
Sparks, D.L.1
-
124
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
Sparks DL, Scheff SW, Hunsaker JC 3rd, Liu H, Landers T, Gross DR. 1994. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol 126(1):88-94.
-
(1994)
Exp. Neurol.
, vol.126
, Issue.1
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker III, J.C.3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
125
-
-
0034663175
-
Link between heart disease, cholesterol, and Alzheimer's disease: A review
-
Sparks DL, Martin TA, Gross DR, Hunsaker JC 3rd. 2000. Link between heart disease, cholesterol, and Alzheimer's disease: A review. Microsc Res Tech 50(4):287-290.
-
(2000)
Microsc. Res. Tech.
, vol.50
, Issue.4
, pp. 287-290
-
-
Sparks, D.L.1
Martin, T.A.2
Gross, D.R.3
Hunsaker III, J.C.4
-
126
-
-
31644445523
-
Benefit of atorvastatin in the treatment of Alzheimer's disease
-
Sparks L. 2004. Benefit of atorvastatin in the treatment of Alzheimer's disease. Springfield Symposium 2004, Montreal.
-
(2004)
Springfield Symposium 2004, Montreal
-
-
Sparks, L.1
-
127
-
-
0032970522
-
Apolipoprotein E genotypes and cognitive functions in healthy elderly persons
-
Staehelin HB, Perrig-Chiello P, Mitrache C, Miserez AR, Perrig WJ. 1999. Apolipoprotein E genotypes and cognitive functions in healthy elderly persons. Acta Neurol Scand 100(1):53-60.
-
(1999)
Acta Neurol. Scand.
, vol.100
, Issue.1
, pp. 53-60
-
-
Staehelin, H.B.1
Perrig-Chiello, P.2
Mitrache, C.3
Miserez, A.R.4
Perrig, W.J.5
-
128
-
-
0023737363
-
Dietary cholesterol and human coronary heart disease. The epidemiologic evidence
-
Stamler J, Shekelle R. 1988. Dietary cholesterol and human coronary heart disease. The epidemiologic evidence. Arch Pathol Lab Med 112(10):1032-1040.
-
(1988)
Arch. Pathol. Lab. Med.
, vol.112
, Issue.10
, pp. 1032-1040
-
-
Stamler, J.1
Shekelle, R.2
-
130
-
-
0027956675
-
High tissue content of soluble beta1-40 is linked to cerebral amyloid angiopathy
-
Suzuki N, Iwatsubo T, Odaka A, Ishibashi Y, Kitada C, Ihara Y. 1994. High tissue content of soluble beta1-40 is linked to cerebral amyloid angiopathy. Am J Pathol 145:452-460.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 452-460
-
-
Suzuki, N.1
Iwatsubo, T.2
Odaka, A.3
Ishibashi, Y.4
Kitada, C.5
Ihara, Y.6
-
131
-
-
0028157335
-
Membrane. lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form(type I) and demyelination in late-onset form(type II)
-
Svennerholm L, Gottfries CG. 1994. Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form(type I) and demyelination in late-onset form(type II). J Neurochem 62(3):1039-1047.
-
(1994)
J. Neurochem.
, vol.62
, Issue.3
, pp. 1039-1047
-
-
Svennerholm, L.1
Gottfries, C.G.2
-
132
-
-
0032507596
-
Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells
-
Svensson AL, Nordberg A. 1998. Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells. Neuroreport 9(7):1519-1522.
-
(1998)
Neuroreport
, vol.9
, Issue.7
, pp. 1519-1522
-
-
Svensson, A.L.1
Nordberg, A.2
-
133
-
-
0035572718
-
Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
-
Takemoto M, Liao JK. 2001. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 21(11):1712-1719.
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, Issue.11
, pp. 1712-1719
-
-
Takemoto, M.1
Liao, J.K.2
-
134
-
-
3042627230
-
Anti-apoptotic effect of atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardiac myocytes through protein kinase C activation
-
Tanaka K, Honda M, Takabatake T. 2004. Anti-apoptotic effect of atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardiac myocytes through protein kinase C activation. Clin Exp Pharmacol Physiol 31(5-6):360-364.
-
(2004)
Clin. Exp. Pharmacol. Physiol.
, vol.31
, Issue.5-6
, pp. 360-364
-
-
Tanaka, K.1
Honda, M.2
Takabatake, T.3
-
135
-
-
0030174981
-
The gene defects responsible for familial Alzheimer's disease
-
Tanzi RE, Kovacs DM, Kim TW, Moir RD, Guenette SY, Wasco W. 1996. The gene defects responsible for familial Alzheimer's disease. Neurobiol Dis 3(3):159-168.
-
(1996)
Neurobiol. Dis.
, vol.3
, Issue.3
, pp. 159-168
-
-
Tanzi, R.E.1
Kovacs, D.M.2
Kim, T.W.3
Moir, R.D.4
Guenette, S.Y.5
Wasco, W.6
-
136
-
-
0000741638
-
Some quantitative cerebral findings in normal and demented old people
-
Terry RD, editor. New York: Raven Press
-
Tomlinson B, Henderson G. 1976. Some quantitative cerebral findings in normal and demented old people. In: Terry RD, editor. Neurobiology of aging. New York: Raven Press.
-
(1976)
Neurobiology of Aging
-
-
Tomlinson, B.1
Henderson, G.2
-
137
-
-
0000383864
-
Ageing and the dementias
-
Hume Adams J, Corsellis JAN, Duchen LW, editors. London: Edward Arnold
-
Tomlinson BE, Corsellis JAN. 1984. Ageing and the dementias. In: Hume Adams J, Corsellis JAN, Duchen LW, editors. Greenfield's neuropathology. London: Edward Arnold. p 951-1025.
-
(1984)
Greenfield's Neuropathology
, pp. 951-1025
-
-
Tomlinson, B.E.1
Corsellis, J.A.N.2
-
138
-
-
0036674082
-
Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway
-
Tun H, Marlow L, Pinnix I, Kinsey R, Sambamurti K. 2002. Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway. J Mol Neurosci 19(1-2):31-35.
-
(2002)
J. Mol. Neurosci.
, vol.19
, Issue.1-2
, pp. 31-35
-
-
Tun, H.1
Marlow, L.2
Pinnix, I.3
Kinsey, R.4
Sambamurti, K.5
-
139
-
-
0345275891
-
Gamma-secretase activity is present in rafts but is not cholesterol-dependent
-
Wada S, Morishima-Kawashima M, Qi Y, Misono H, Shimada Y, Ohno-Iwashita Y, Ihara Y. 2003. Gamma-secretase activity is present in rafts but is not cholesterol-dependent. Biochemistry 42(47):13977-13986.
-
(2003)
Biochemistry
, vol.42
, Issue.47
, pp. 13977-13986
-
-
Wada, S.1
Morishima-Kawashima, M.2
Qi, Y.3
Misono, H.4
Shimada, Y.5
Ohno-Iwashita, Y.6
Ihara, Y.7
-
140
-
-
0034609516
-
The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain
-
Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ. 2000. The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain. Biochemistry 39(35):10831-10839.
-
(2000)
Biochemistry
, vol.39
, Issue.35
, pp. 10831-10839
-
-
Walsh, D.M.1
Tseng, B.P.2
Rydel, R.E.3
Podlisny, M.B.4
Selkoe, D.J.5
-
141
-
-
0036162113
-
Cellular antioxidant effects of atorvastatin in vitro and in vivo
-
Wassmann S, Laufs U, Muller K, Konkol C, Ahlbory K, Baumer AT, Linz W, Bohm M, Nickenig G. 2002. Cellular antioxidant effects of atorvastatin in vitro and in vivo. Arterioscler Thromb Vasc Biol 22(2):300-305.
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, Issue.2
, pp. 300-305
-
-
Wassmann, S.1
Laufs, U.2
Muller, K.3
Konkol, C.4
Ahlbory, K.5
Baumer, A.T.6
Linz, W.7
Bohm, M.8
Nickenig, G.9
-
142
-
-
0000306390
-
Statins do more than just lower cholesterol
-
Vaughan CJ, Murphy MB, Buckley BM. 1996. Statins do more than just lower cholesterol. Lancet 348(9034):1079-1082.
-
(1996)
Lancet
, vol.348
, Issue.9034
, pp. 1079-1082
-
-
Vaughan, C.J.1
Murphy, M.B.2
Buckley, B.M.3
-
143
-
-
0037388527
-
Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease
-
Vega GL, Weiner MF, Lipton AM, Von Bergmann K, Lutjohann D, Moore C, Svetlik D. 2003. Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease. Arch Neurol 60(4):510-515.
-
(2003)
Arch. Neurol.
, vol.60
, Issue.4
, pp. 510-515
-
-
Vega, G.L.1
Weiner, M.F.2
Lipton, A.M.3
Von Bergmann, K.4
Lutjohann, D.5
Moore, C.6
Svetlik, D.7
-
144
-
-
18144435700
-
Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys
-
Williams JK, Sukhova GK, Herrington DM, Libby P. 1998. Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys. J Am Coll Cardiol 31(3):684-691.
-
(1998)
J. Am. Coll. Cardiol.
, vol.31
, Issue.3
, pp. 684-691
-
-
Williams, J.K.1
Sukhova, G.K.2
Herrington, D.M.3
Libby, P.4
-
145
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
-
Wischik CM, Novak M, Thogersen HC, Edwards PC, Runswick MJ, Jakes R, Walker JE, Milstein C, Roth M, Klug A. 1988. Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc Natl Acad Sci USA 85(12):4506-4510.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, Issue.12
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thogersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Roth, M.9
Klug, A.10
-
146
-
-
0018372161
-
Alzheimer neurofibrillary tangles in diseases other than senile and presenile dementia
-
Wisniewski K, George A, Moretz R, Wisniewski H. 1979. Alzheimer neurofibrillary tangles in diseases other than senile and presenile dementia. Ann Neurol 5:288-294.
-
(1979)
Ann. Neurol.
, vol.5
, pp. 288-294
-
-
Wisniewski, K.1
George, A.2
Moretz, R.3
Wisniewski, H.4
-
147
-
-
0033772113
-
Decreased prevalence of alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
-
Wolozin B, Kellman W, Ruosseau P, Celesia GG, Siegel G. 2000. Decreased prevalence of alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57(10):1439-1443.
-
(2000)
Arch. Neurol.
, vol.57
, Issue.10
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Ruosseau, P.3
Celesia, G.G.4
Siegel, G.5
-
148
-
-
0038182452
-
Brain region-dependent increases in beta-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits
-
Wu CW, Liao PC, Lin C, Kuo CJ, Chen ST, Chen H, Kuo YM. 2003. Brain region-dependent increases in beta-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits. J Neural Transm 110(6):641-649.
-
(2003)
J. Neural. Transm.
, vol.110
, Issue.6
, pp. 641-649
-
-
Wu, C.W.1
Liao, P.C.2
Lin, C.3
Kuo, C.J.4
Chen, S.T.5
Chen, H.6
Kuo, Y.M.7
-
149
-
-
0036186663
-
Serum lipoprotein levels, statin use, and cognitive function in older women
-
Yaffe K, Barrett-Connor E, Lin F, Grady D. 2002. Serum lipoprotein levels, statin use, and cognitive function in older women. Arch Neurol 59(3):378-384.
-
(2002)
Arch. Neurol.
, vol.59
, Issue.3
, pp. 378-384
-
-
Yaffe, K.1
Barrett-Connor, E.2
Lin, F.3
Grady, D.4
-
150
-
-
0032568821
-
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin
-
Yu G, Chen F, Levesque G, Nishimura M, Zhang DM, Levesque L, Rogaeva E, Xu D, Liang Y, Duthie M, St George-Hyslop PH, Fraser PE. 1998. The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin. J Biol Chem 273(26):16470-16475.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.26
, pp. 16470-16475
-
-
Yu, G.1
Chen, F.2
Levesque, G.3
Nishimura, M.4
Zhang, D.M.5
Levesque, L.6
Rogaeva, E.7
Xu, D.8
Liang, Y.9
Duthie, M.10
St George-Hyslop, P.H.11
Fraser, P.E.12
|