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Volumn 6, Issue 2, 2005, Pages 85-97

The link between cholesterol and Alzheimer's disease

Author keywords

amyloid; secretase; Amyloid precursor protein; Cholesterol; Statins

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E4; ATORVASTATIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA SECRETASE; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; DIURETIC AGENT; GAMMA SECRETASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METHYL BETA CYCLODEXTRIN; MEVINOLIN; OLIGOMER; PRAVASTATIN; PRESENILIN 1; PRESENILIN 2; ROSUVASTATIN; SIMVASTATIN;

EID: 21244494408     PISSN: 15622975     EISSN: None     Source Type: Journal    
DOI: 10.1080/15622970510029795     Document Type: Review
Times cited : (50)

References (150)
  • 1
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • 4S-study-group
    • S-study-group. 1994. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 344(8934):1383-1389.
    • (1994) Lancet , vol.344 , Issue.8934 , pp. 1383-1389
  • 2
    • 0034066646 scopus 로고    scopus 로고
    • Alzheimer's disease and vascular dementia. Some points of confluence
    • Aguero-Torres H, Winblad B. 2000. Alzheimer's disease and vascular dementia. Some points of confluence. Ann NY Acad Sci 903:547-552.
    • (2000) Ann. NY Acad. Sci. , vol.903 , pp. 547-552
    • Aguero-Torres, H.1    Winblad, B.2
  • 3
    • 0020007559 scopus 로고
    • The role of apolipoproteins in lipid transport processes
    • Alaupovic P. 1982. The role of apolipoproteins in lipid transport processes. Ric Clin Lab 12(1):3-21.
    • (1982) Ric. Clin. Lab. , vol.12 , Issue.1 , pp. 3-21
    • Alaupovic, P.1
  • 6
    • 0031882562 scopus 로고    scopus 로고
    • Beta-amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons
    • Beffert U, Aumont N, Dea D, Lussier Cacan S, Davignon J, Poirier J. 1998. Beta-amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons. J Neurochem 70(4):1458-1466.
    • (1998) J. Neurochem. , vol.70 , Issue.4 , pp. 1458-1466
    • Beffert, U.1    Aumont, N.2    Dea, D.3    Lussier Cacan, S.4    Davignon, J.5    Poirier, J.6
  • 8
    • 0030009670 scopus 로고    scopus 로고
    • Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease
    • Beffert U, Poirier J. 1996. Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease. Ann NY Acad Sci 777:166-174.
    • (1996) Ann. NY Acad. Sci. , vol.777 , pp. 166-174
    • Beffert, U.1    Poirier, J.2
  • 9
    • 0032487497 scopus 로고    scopus 로고
    • ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation
    • Beffert U, Poirier J. 1998. ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation. Neuroreport 9(14):3321-3323.
    • (1998) Neuroreport , vol.9 , Issue.14 , pp. 3321-3323
    • Beffert, U.1    Poirier, J.2
  • 10
    • 0032751475 scopus 로고    scopus 로고
    • Genetic testing for Alzheimer's disease: How close is reality?
    • Blennow K, Skoog I. 1999. Genetic testing for Alzheimer's disease: How close is reality? Curr Opin Psychiatry 12:487-493.
    • (1999) Curr. Opin. Psychiatry , vol.12 , pp. 487-493
    • Blennow, K.1    Skoog, I.2
  • 11
    • 0034068864 scopus 로고    scopus 로고
    • Statins: Effective antiatherosclerotic therapy
    • Blumenthal RS. 2000. Statins: Effective antiatherosclerotic therapy. Am Heart J 139(4):577-583.
    • (2000) Am. Heart J. , vol.139 , Issue.4 , pp. 577-583
    • Blumenthal, R.S.1
  • 12
    • 0029671454 scopus 로고    scopus 로고
    • Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
    • Bodovitz S, Klein WL. 1996. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271(8):4436-4440.
    • (1996) J. Biol. Chem. , vol.271 , Issue.8 , pp. 4436-4440
    • Bodovitz, S.1    Klein, W.L.2
  • 13
    • 0036015984 scopus 로고    scopus 로고
    • Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes
    • Bonn V, Cheung RC, Chen B, Taghibiglou C, Van Iderstine SC, Adeli K. 2002. Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes. Atherosclerosis 163(1):59-68.
    • (2002) Atherosclerosis , vol.163 , Issue.1 , pp. 59-68
    • Bonn, V.1    Cheung, R.C.2    Chen, B.3    Taghibiglou, C.4    Van Iderstine, S.C.5    Adeli, K.6
  • 16
    • 0028227379 scopus 로고
    • Cardiovascular disease and distribution of cognitive function in elderly people: The Rotterdam Study
    • Breteler MM, Claus JJ, Grobbee DE, Hofman A. 1994. Cardiovascular disease and distribution of cognitive function in elderly people: The Rotterdam Study. Br Med J 308(6944):1604-1608.
    • (1994) Br. Med. J. , vol.308 , Issue.6944 , pp. 1604-1608
    • Breteler, M.M.1    Claus, J.J.2    Grobbee, D.E.3    Hofman, A.4
  • 17
    • 0031695197 scopus 로고    scopus 로고
    • Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    • Brookmeyer R, Gray S, Kawas C. 1998. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 88(9):1337-1342.
    • (1998) Am. J. Public Health , vol.88 , Issue.9 , pp. 1337-1342
    • Brookmeyer, R.1    Gray, S.2    Kawas, C.3
  • 18
    • 0027322448 scopus 로고
    • Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease
    • Brown BG, Zhao XQ, Sacco DE, Albers JJ. 1993. Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease. Circulation 87(6):1781-1791.
    • (1993) Circulation , vol.87 , Issue.6 , pp. 1781-1791
    • Brown, B.G.1    Zhao, X.Q.2    Sacco, D.E.3    Albers, J.J.4
  • 19
    • 0036860349 scopus 로고    scopus 로고
    • Metal complexing agents as therapies for Alzheimer's disease
    • Bush AI. 2002. Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging 23(6):1031-1038.
    • (2002) Neurobiol. Aging , vol.23 , Issue.6 , pp. 1031-1038
    • Bush, A.I.1
  • 20
    • 0141483385 scopus 로고    scopus 로고
    • Copper, zinc, and the metallobiology of Alzheimer disease
    • Bush AI. 2003. Copper, zinc, and the metallobiology of Alzheimer disease. Alzheimer Dis Assoc Disord 17(3):147-150.
    • (2003) Alzheimer Dis. Assoc. Disord. , vol.17 , Issue.3 , pp. 147-150
    • Bush, A.I.1
  • 21
    • 0028180196 scopus 로고
    • Modulation of A beta adhesiveness and secretase site cleavage by zinc
    • Bush AI, Pettingell WH Jr, Paradis MD, Tanzi RE. 1994a. Modulation of A beta adhesiveness and secretase site cleavage by zinc. J Biol Chem 269(16):12152-12158.
    • (1994) J. Biol. Chem. , vol.269 , Issue.16 , pp. 12152-12158
    • Bush, A.I.1    Pettingell Jr., W.H.2    Paradis, M.D.3    Tanzi, R.E.4
  • 26
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
    • Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. 2001. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 103(7):926-933.
    • (2001) Circulation , vol.103 , Issue.7 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3    Yano, J.4    Zhu, J.5    Nilsson, J.6
  • 27
    • 0022435132 scopus 로고
    • Image reconstruction of the Alzheimer paired helical filament
    • Crowther RA, Wischik CM. 1985. Image reconstruction of the Alzheimer paired helical filament. EMBO J 4(13B):3661-3665.
    • (1985) EMBO J. , vol.4 , Issue.13 B , pp. 3661-3665
    • Crowther, R.A.1    Wischik, C.M.2
  • 28
    • 0035875462 scopus 로고    scopus 로고
    • Use of statins in CNS disorders
    • Cucchiara B, Kasner SE. 2001. Use of statins in CNS disorders. J Neurol Sci 187(1-2):81-89.
    • (2001) J. Neurol. Sci. , vol.187 , Issue.1-2 , pp. 81-89
    • Cucchiara, B.1    Kasner, S.E.2
  • 29
    • 0033393022 scopus 로고    scopus 로고
    • Low-density lipoprotein-independent effects of statins
    • Davignon J, Laaksonen R. 1999. Low-density lipoprotein-independent effects of statins. Curr Opin Lipidol 10(6):543-59.
    • (1999) Curr. Opin. Lipidol. , vol.10 , Issue.6 , pp. 543-559
    • Davignon, J.1    Laaksonen, R.2
  • 30
    • 0036218738 scopus 로고    scopus 로고
    • Alzheimer disease as a vascular disorder: Nosological evidence
    • de la Torre JC. 2002. Alzheimer disease as a vascular disorder: Nosological evidence. Stroke 33 (4): 1152-1162.
    • (2002) Stroke , vol.33 , Issue.4 , pp. 1152-1162
    • de la Torre, J.C.1
  • 32
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
    • DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. 2001. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 98(15):8850-8855.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.15 , pp. 8850-8855
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.C.4    Paul, S.M.5    Holtzman, D.M.6
  • 34
    • 0035901715 scopus 로고    scopus 로고
    • Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice
    • Eckert GP, Kirsch C, Mueller WE. 2001. Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice. Neuroreport 12(5):883-887.
    • (2001) Neuroreport , vol.12 , Issue.5 , pp. 883-887
    • Eckert, G.P.1    Kirsch, C.2    Mueller, W.E.3
  • 35
    • 0037421206 scopus 로고    scopus 로고
    • Amyloidogenic processing of the Alzheimer {beta}-amyloid precursor protein depends on lipid rafts
    • Ehehalt R, Keller P, Haass C, Thiele C, Simons K. 2003. Amyloidogenic processing of the Alzheimer {beta}-amyloid precursor protein depends on lipid rafts. J Cell Biol 160(1):113-123.
    • (2003) J. Cell Biol. , vol.160 , Issue.1 , pp. 113-123
    • Ehehalt, R.1    Keller, P.2    Haass, C.3    Thiele, C.4    Simons, K.5
  • 36
    • 0023764870 scopus 로고
    • Familial hypercholesterolemia and apolipoprotein E4
    • Eto M, Watanabe K, Chonan N, Ishii K. 1988. Familial hypercholesterolemia and apolipoprotein E4. Atherosclerosis 72(2-3):123-128.
    • (1988) Atherosclerosis , vol.72 , Issue.2-3 , pp. 123-128
    • Eto, M.1    Watanabe, K.2    Chonan, N.3    Ishii, K.4
  • 38
    • 0141960033 scopus 로고    scopus 로고
    • Beta-Amyloid induces paired helical filament-like tau filaments in tissue culture
    • Ferrari A, Hoerndli F, Baechi T, Nitsch RM, Gotz J. 2003. beta-Amyloid induces paired helical filament-like tau filaments in tissue culture. J Biol Chem 278(41):40162-40168.
    • (2003) J. Biol. Chem. , vol.278 , Issue.41 , pp. 40162-40168
    • Ferrari, A.1    Hoerndli, F.2    Baechi, T.3    Nitsch, R.M.4    Gotz, J.5
  • 39
    • 0042021925 scopus 로고    scopus 로고
    • Current status of metals as therapeutic targets in Alzheimer's disease
    • Finefrock AE, Bush AI, Doraiswamy PM. 2003. Current status of metals as therapeutic targets in Alzheimer's disease. J Am Geriatr Soc 51(8):1143-1148.
    • (2003) J. Am. Geriatr. Soc. , vol.51 , Issue.8 , pp. 1143-1148
    • Finefrock, A.E.1    Bush, A.I.2    Doraiswamy, P.M.3
  • 41
    • 0024779411 scopus 로고
    • Neurobiology of zinc and zinc-containing neurons
    • Frederickson CJ. 1989. Neurobiology of zinc and zinc-containing neurons. Int Rev Neurobiol 31:145-238.
    • (1989) Int. Rev. Neurobiol. , vol.31 , pp. 145-238
    • Frederickson, C.J.1
  • 42
    • 0034956750 scopus 로고    scopus 로고
    • Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide
    • Friedhoff LT, Cullen EI, Geoghagen NS, Buxbaum JD. 2001. Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide. Int J Neuropsychopharmacol 4(2):127-130.
    • (2001) Int. J. Neuropsychopharmacol. , vol.4 , Issue.2 , pp. 127-130
    • Friedhoff, L.T.1    Cullen, E.I.2    Geoghagen, N.S.3    Buxbaum, J.D.4
  • 44
    • 0034214328 scopus 로고    scopus 로고
    • Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway
    • Galbete JL, Martin TR, Peressini E, Modena P, Bianchi R, Forloni G. 2000. Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway. Biochem J 348(Pt 2):307-313.
    • (2000) Biochem. J. , vol.348 , Issue.PART 2 , pp. 307-313
    • Galbete, J.L.1    Martin, T.R.2    Peressini, E.3    Modena, P.4    Bianchi, R.5    Forloni, G.6
  • 46
    • 0031824782 scopus 로고    scopus 로고
    • Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity
    • Geula C, Wu CK, Saroff D, Lorenzo A, Yuan M, Yankner BA. 1998. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity. Nat Med 4(7):827-831.
    • (1998) Nat. Med. , vol.4 , Issue.7 , pp. 827-831
    • Geula, C.1    Wu, C.K.2    Saroff, D.3    Lorenzo, A.4    Yuan, M.5    Yankner, B.A.6
  • 47
    • 0027420369 scopus 로고
    • Tau protein and the neurofibrillary pathology of Alzheimer's disease
    • Goedert M. 1993. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends Neurosci 16(11):460-465.
    • (1993) Trends Neurosci. , vol.16 , Issue.11 , pp. 460-465
    • Goedert, M.1
  • 48
    • 0002792366 scopus 로고
    • Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
    • Goedert M, Wischik CM, Crowther RA, Walker JE, Klug A. 1988. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau. Proc Natl Acad Sci USA 85(11):4051-4055.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , Issue.11 , pp. 4051-4055
    • Goedert, M.1    Wischik, C.M.2    Crowther, R.A.3    Walker, J.E.4    Klug, A.5
  • 49
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Abeta 42 fibrils
    • Gotz J, Chen F, van Dorpe J, Nitsch RM. 2001. Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Abeta 42 fibrils. Science 293(5534):1491-1495.
    • (2001) Science , vol.293 , Issue.5534 , pp. 1491-1495
    • Gotz, J.1    Chen, F.2    van Dorpe, J.3    Nitsch, R.M.4
  • 50
  • 51
    • 0027333557 scopus 로고
    • Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide
    • Haass C, Selkoe DJ. 1993. Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell 75(6):1039-1042.
    • (1993) Cell , vol.75 , Issue.6 , pp. 1039-1042
    • Haass, C.1    Selkoe, D.J.2
  • 52
    • 0025899041 scopus 로고
    • Amyloid deposition as the central event in the aetiology of Alzheimer's disease
    • Hardy J, Allsop D. 1991. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 12:383-388.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 383-388
    • Hardy, J.1    Allsop, D.2
  • 53
    • 0028298389 scopus 로고
    • Apolipoprotein E and cholesterol affect neuronal calcium signalling: The possible relationship to beta-amyloid neurotoxicity
    • Hartmann H, Eckert A, Muller WE. 1994. Apolipoprotein E and cholesterol affect neuronal calcium signalling: The possible relationship to beta-amyloid neurotoxicity. Biochem Biophys Res Commun 200(3):1185-1192.
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , Issue.3 , pp. 1185-1192
    • Hartmann, H.1    Eckert, A.2    Muller, W.E.3
  • 54
    • 0023616195 scopus 로고
    • Low density lipoprotein receptor regulation and the cellular basis of atherosclerosis: Implications for nutritional and pharmacologic treatment of hypercholesterolemia
    • Heber D, Koziol BJ, Henson LC. 1987. Low density lipoprotein receptor regulation and the cellular basis of atherosclerosis: Implications for nutritional and pharmacologic treatment of hypercholesterolemia. Am J Cardiol 60(12):4-8G.
    • (1987) Am. J. Cardiol. , vol.60 , Issue.12
    • Heber, D.1    Koziol, B.J.2    Henson, L.C.3
  • 55
    • 0030802435 scopus 로고    scopus 로고
    • Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials
    • Hebert PR, Gaziano JM, Chan KS, Hennekens CH. 1997. Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. J Am Med Assoc 278(4):313-321.
    • (1997) J. Am. Med. Assoc. , vol.278 , Issue.4 , pp. 313-321
    • Hebert, P.R.1    Gaziano, J.M.2    Chan, K.S.3    Hennekens, C.H.4
  • 56
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
    • Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, Sanchez-Pascuala R, Hernandez G, Diaz C, Lamas S. 1998. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J Clin Invest 101(12):2711-2719.
    • (1998) J. Clin. Invest. , vol.101 , Issue.12 , pp. 2711-2719
    • Hernandez-Perera, O.1    Perez-Sala, D.2    Navarro-Antolin, J.3    Sanchez-Pascuala, R.4    Hernandez, G.5    Diaz, C.6    Lamas, S.7
  • 57
    • 0034730781 scopus 로고    scopus 로고
    • Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells
    • Hernandez-Perera O, Perez-Sala D, Soria E, Lamas S. 2000. Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells. Circ Res 87(7):616-622.
    • (2000) Circ. Res. , vol.87 , Issue.7 , pp. 616-622
    • Hernandez-Perera, O.1    Perez-Sala, D.2    Soria, E.3    Lamas, S.4
  • 62
    • 0037028782 scopus 로고    scopus 로고
    • Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: A randomized controlled trial
    • Jula A, Marniemi J, Huupponen R, Virtanen A, Pastas M, Ronnemaa T. 2002. Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: A randomized controlled trial. J Am Med Assoc 287(5):598-605.
    • (2002) J. Am. Med. Assoc. , vol.287 , Issue.5 , pp. 598-605
    • Jula, A.1    Marniemi, J.2    Huupponen, R.3    Virtanen, A.4    Pastas, M.5    Ronnemaa, T.6
  • 63
    • 0034980106 scopus 로고    scopus 로고
    • Intracellular calcium changes in neuronal cells induced by Alzheimer's beta-amyloid protein are blocked by estradiol and cholesterol
    • Kawahara M, Kuroda Y. 2001. Intracellular calcium changes in neuronal cells induced by Alzheimer's beta-amyloid protein are blocked by estradiol and cholesterol. Cell Mol Neurobiol 21(1):1-13.
    • (2001) Cell Mol. Neurobiol. , vol.21 , Issue.1 , pp. 1-13
    • Kawahara, M.1    Kuroda, Y.2
  • 64
    • 37049048544 scopus 로고
    • Paired helical filaments in electron microscopy of Alzheimer's disease
    • Kidd M. 1963. Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 197:192-193.
    • (1963) Nature , vol.197 , pp. 192-193
    • Kidd, M.1
  • 67
    • 0035826909 scopus 로고    scopus 로고
    • Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10
    • Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F. 2001. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10. Proc Natl Acad Sci USA 98(10):5815-5820.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.10 , pp. 5815-5820
    • Kojro, E.1    Gimpl, G.2    Lammich, S.3    Marz, W.4    Fahrenholz, F.5
  • 69
    • 0028176821 scopus 로고
    • Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
    • Kurochkin IV, Goto S. 1994. Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett 345(1):33-37.
    • (1994) FEBS Lett. , vol.345 , Issue.1 , pp. 33-37
    • Kurochkin, I.V.1    Goto, S.2
  • 70
    • 0037465360 scopus 로고    scopus 로고
    • Reduced connexin3 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice
    • Kwak BR, Veillard N, Pelli G, Mulhaupt F, James RW, Chanson M, Mach F. 2003. Reduced connexin3 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice. Circulation 107(7):1033-1039.
    • (2003) Circulation , vol.107 , Issue.7 , pp. 1033-1039
    • Kwak, B.R.1    Veillard, N.2    Pelli, G.3    Mulhaupt, F.4    James, R.W.5    Chanson, M.6    Mach, F.7
  • 71
    • 0033800718 scopus 로고    scopus 로고
    • Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice
    • Laufs U, Gertz K, Huang P, Nickenig G, Bohm M, Dirnagl U, Endres M. 2000. Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice. Stroke 31(10):2442-2449.
    • (2000) Stroke , vol.31 , Issue.10 , pp. 2442-2449
    • Laufs, U.1    Gertz, K.2    Huang, P.3    Nickenig, G.4    Bohm, M.5    Dirnagl, U.6    Endres, M.7
  • 72
    • 0030953045 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences
    • Lennernas H, Fager G. 1997. Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clin Pharmacokinet 32(5):403-425.
    • (1997) Clin. Pharmacokinet. , vol.32 , Issue.5 , pp. 403-425
    • Lennernas, H.1    Fager, G.2
  • 75
    • 0036128358 scopus 로고    scopus 로고
    • Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: Evidence that simvastatin affects cholesterol metabolism in the human brain
    • Locatelli S, Lutjohann D, Schmidt HH, Otto C, Beisiegel U, von Bergmann K. 2002. Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: Evidence that simvastatin affects cholesterol metabolism in the human brain. Arch Neurol 59(2):213-216.
    • (2002) Arch. Neurol. , vol.59 , Issue.2 , pp. 213-216
    • Locatelli, S.1    Lutjohann, D.2    Schmidt, H.H.3    Otto, C.4    Beisiegel, U.5    von Bergmann, K.6
  • 78
    • 0033984436 scopus 로고    scopus 로고
    • Current perspectives on statins
    • Maron DJ, Fazio S, Linton MF. 2000. Current perspectives on statins. Circulation 101(2):207-213.
    • (2000) Circulation , vol.101 , Issue.2 , pp. 207-213
    • Maron, D.J.1    Fazio, S.2    Linton, M.F.3
  • 79
    • 0033968648 scopus 로고    scopus 로고
    • Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
    • Michikawa M, Fan QW, Isobe I, Yanagisawa K. 2000. Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 74(3):1008-1016.
    • (2000) J. Neurochem. , vol.74 , Issue.3 , pp. 1008-1016
    • Michikawa, M.1    Fan, Q.W.2    Isobe, I.3    Yanagisawa, K.4
  • 80
    • 0141452104 scopus 로고    scopus 로고
    • Reduction in serum levels of adhesion molecules, interleukin-6 and C-reactive protein following short-term low-dose atorvastatin treatment in patients with non-familial hypercholesterolemia
    • Nawawi H, Osman NS, Yusoff K, Khalid BA. 2003. Reduction in serum levels of adhesion molecules, interleukin-6 and C-reactive protein following short-term low-dose atorvastatin treatment in patients with non-familial hypercholesterolemia. Horm Metab Res 35(8):479-485.
    • (2003) Horm. Metab. Res. , vol.35 , Issue.8 , pp. 479-485
    • Nawawi, H.1    Osman, N.S.2    Yusoff, K.3    Khalid, B.A.4
  • 82
    • 0029450271 scopus 로고
    • The amyloid peptide precursor in Alzheimer's disease
    • Octave JN. 1995. The amyloid peptide precursor in Alzheimer's disease. Acta Neurol Belg 95(4):197-209.
    • (1995) Acta Neurol. Belg. , vol.95 , Issue.4 , pp. 197-209
    • Octave, J.N.1
  • 88
    • 11444256434 scopus 로고    scopus 로고
    • Apolipoprotein E: A Novel therapeutic target for the treatment of Alzheimer's disease
    • Poirier J, Panisset M. 2002. Apolipoprotein E: A Novel therapeutic target for the treatment of Alzheimer's disease. Adv Behav Biol 1:36-42.
    • (2002) Adv. Behav. Biol. , vol.1 , pp. 36-42
    • Poirier, J.1    Panisset, M.2
  • 89
    • 2542454942 scopus 로고    scopus 로고
    • Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex
    • Prokop S, Shirotani K, Edbauer D, Haass C, Steiner H. 2004. Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex. J Biol Chem 279(22):23255-23261.
    • (2004) J. Biol. Chem. , vol.279 , Issue.22 , pp. 23255-23261
    • Prokop, S.1    Shirotani, K.2    Edbauer, D.3    Haass, C.4    Steiner, H.5
  • 95
    • 0035853154 scopus 로고    scopus 로고
    • Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease
    • Reiman EM, Caselli RJ, Chen K, Alexander GE, Bandy D, Frost J. 2001. Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci USA 98(6):3334-3339.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.6 , pp. 3334-3339
    • Reiman, E.M.1    Caselli, R.J.2    Chen, K.3    Alexander, G.E.4    Bandy, D.5    Frost, J.6
  • 97
    • 0038240721 scopus 로고    scopus 로고
    • Causative and susceptibility genes for Alzheimer's disease: A review
    • Rocchi A, Pellegrini S, Siciliano G, Murri L. 2003. Causative and susceptibility genes for Alzheimer's disease: A review. Brain Res Bull 61(1):1-24.
    • (2003) Brain Res. Bull. , vol.61 , Issue.1 , pp. 1-24
    • Rocchi, A.1    Pellegrini, S.2    Siciliano, G.3    Murri, L.4
  • 99
    • 0034643888 scopus 로고    scopus 로고
    • The molecular and genetic basis of AD: The end of the beginning: The 2000 Wartenberg Lecture
    • Rosenberg RN. 2000. The molecular and genetic basis of AD: The end of the beginning: The 2000 Wartenberg Lecture. Neurology 54(11):2045-2054.
    • (2000) Neurology , vol.54 , Issue.11 , pp. 2045-2054
    • Rosenberg, R.N.1
  • 100
    • 0035081589 scopus 로고    scopus 로고
    • Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: Structure and function in atherosclerosis
    • Rudel LL, Lee RG, Cockman TL. 2001. Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr Opin Lipidol 12(2):121-127.
    • (2001) Curr. Opin. Lipidol. , vol.12 , Issue.2 , pp. 121-127
    • Rudel, L.L.1    Lee, R.G.2    Cockman, T.L.3
  • 101
    • 0036523031 scopus 로고    scopus 로고
    • Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells
    • Runz H, Rietdorf J, Tomic I, de Bernard M, Beyreuther K, Pepperkok R, Hartmann T. 2002. Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J Neurosci 22(5):1679-1689.
    • (2002) J. Neurosci. , vol.22 , Issue.5 , pp. 1679-1689
    • Runz, H.1    Rietdorf, J.2    Tomic, I.3    de Bernard, M.4    Beyreuther, K.5    Pepperkok, R.6    Hartmann, T.7
  • 102
    • 0035954426 scopus 로고    scopus 로고
    • The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
    • Sabo SL, Ikin AF, Buxbaum JD, Greengard P. 2001. The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. J Cell Biol 153(7):1403-1414.
    • (2001) J. Cell Biol. , vol.153 , Issue.7 , pp. 1403-1414
    • Sabo, S.L.1    Ikin, A.F.2    Buxbaum, J.D.3    Greengard, P.4
  • 104
    • 0025675999 scopus 로고
    • Familial hypercholesterolemia: Dissection of a receptor disease
    • Schneider WJ. 1990. Familial hypercholesterolemia: Dissection of a receptor disease. Z Kardiol 79(Suppl 3):3-7.
    • (1990) Z. Kardiol. , vol.79 , Issue.SUPPL. 3 , pp. 3-7
    • Schneider, W.J.1
  • 106
  • 107
    • 0034516988 scopus 로고    scopus 로고
    • Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein
    • Selkoe DJ. 2000. Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Ann NY Acad Sci 924:17-25.
    • (2000) Ann. NY Acad. Sci. , vol.924 , pp. 17-25
    • Selkoe, D.J.1
  • 109
    • 0034529050 scopus 로고    scopus 로고
    • How cells handle cholesterol
    • Simons K, Ikonen E. 2000. How cells handle cholesterol. Science 290(5497):1721-1726.
    • (2000) Science , vol.290 , Issue.5497 , pp. 1721-1726
    • Simons, K.1    Ikonen, E.2
  • 112
    • 0021824223 scopus 로고
    • Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation
    • Sing CF, Davignon J. 1985. Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet 37(2):268-285.
    • (1985) Am. J. Hum. Genet. , vol.37 , Issue.2 , pp. 268-285
    • Sing, C.F.1    Davignon, J.2
  • 114
    • 0031569486 scopus 로고    scopus 로고
    • Elevated blood pressure and Alzheimer's disease
    • 16, 21
    • Skoog I. 1997. Elevated blood pressure and Alzheimer's disease. Hosp Pract(Off Ed) 32(4):13-14, 16, 21.
    • (1997) Hosp. Pract. (Off. Ed.) , vol.32 , Issue.4 , pp. 13-14
    • Skoog, I.1
  • 115
    • 0002723163 scopus 로고    scopus 로고
    • The interaction between vascular disorders and Alzheimer's disease
    • Wisniewski H, editor. Chichester: John Wiley & Sons Ltd
    • Skoog I. 1999. The interaction between vascular disorders and Alzheimer's disease. In: Wisniewski H, editor. Alzheimer's disease and related disorders: Etiology, Pathogenesis and therapeutics. Chichester: John Wiley & Sons Ltd. p 523-530.
    • (1999) Alzheimer's Disease and Related Disorders: Etiology, Pathogenesis and Therapeutics , pp. 523-530
    • Skoog, I.1
  • 116
    • 0033251235 scopus 로고    scopus 로고
    • HRT and dementia
    • discussion 252
    • Skoog I, Gustafson D. 1999. HRT and dementia. J Epidemiol Biostat 4(3) :227-251; discussion 252.
    • (1999) J. Epidemiol. Biostat. , vol.4 , Issue.3 , pp. 227-251
    • Skoog, I.1    Gustafson, D.2
  • 117
    • 0029886238 scopus 로고    scopus 로고
    • High blood pressure and dementia
    • Skoog I, Lernfelt B, Landahl S. 1996a. High blood pressure and dementia. Lancet 348:65-66.
    • (1996) Lancet , vol.348 , pp. 65-66
    • Skoog, I.1    Lernfelt, B.2    Landahl, S.3
  • 121
    • 0028213567 scopus 로고
    • A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
    • Small DH, Nurcombe V, Reed G, Clarris H, Moir R, Beyreuther K, Masters CL. 1994. A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. J Neurosci 14(4):2117-2127.
    • (1994) J. Neurosci. , vol.14 , Issue.4 , pp. 2117-2127
    • Small, D.H.1    Nurcombe, V.2    Reed, G.3    Clarris, H.4    Moir, R.5    Beyreuther, K.6    Masters, C.L.7
  • 122
    • 0031911493 scopus 로고    scopus 로고
    • Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects
    • Smith GE, Bohac DL, Waring SC, Kokmen E, Tangalos EG, Ivnik RJ, Petersen RC. 1998. Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects. Neurology 50(2):355-362.
    • (1998) Neurology , vol.50 , Issue.2 , pp. 355-362
    • Smith, G.E.1    Bohac, D.L.2    Waring, S.C.3    Kokmen, E.4    Tangalos, E.G.5    Ivnik, R.J.6    Petersen, R.C.7
  • 123
    • 9844226208 scopus 로고    scopus 로고
    • Coronary artery disease, hypertension, ApoE, and cholesterol: A link to Alzheimer's disease?
    • Sparks DL. 1997. Coronary artery disease, hypertension, ApoE, and cholesterol: A link to Alzheimer's disease? Ann NY Acad Sci 826:128-146.
    • (1997) Ann. NY Acad. Sci. , vol.826 , pp. 128-146
    • Sparks, D.L.1
  • 124
    • 0028177562 scopus 로고
    • Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
    • Sparks DL, Scheff SW, Hunsaker JC 3rd, Liu H, Landers T, Gross DR. 1994. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol 126(1):88-94.
    • (1994) Exp. Neurol. , vol.126 , Issue.1 , pp. 88-94
    • Sparks, D.L.1    Scheff, S.W.2    Hunsaker III, J.C.3    Liu, H.4    Landers, T.5    Gross, D.R.6
  • 125
    • 0034663175 scopus 로고    scopus 로고
    • Link between heart disease, cholesterol, and Alzheimer's disease: A review
    • Sparks DL, Martin TA, Gross DR, Hunsaker JC 3rd. 2000. Link between heart disease, cholesterol, and Alzheimer's disease: A review. Microsc Res Tech 50(4):287-290.
    • (2000) Microsc. Res. Tech. , vol.50 , Issue.4 , pp. 287-290
    • Sparks, D.L.1    Martin, T.A.2    Gross, D.R.3    Hunsaker III, J.C.4
  • 126
    • 31644445523 scopus 로고    scopus 로고
    • Benefit of atorvastatin in the treatment of Alzheimer's disease
    • Sparks L. 2004. Benefit of atorvastatin in the treatment of Alzheimer's disease. Springfield Symposium 2004, Montreal.
    • (2004) Springfield Symposium 2004, Montreal
    • Sparks, L.1
  • 128
    • 0023737363 scopus 로고
    • Dietary cholesterol and human coronary heart disease. The epidemiologic evidence
    • Stamler J, Shekelle R. 1988. Dietary cholesterol and human coronary heart disease. The epidemiologic evidence. Arch Pathol Lab Med 112(10):1032-1040.
    • (1988) Arch. Pathol. Lab. Med. , vol.112 , Issue.10 , pp. 1032-1040
    • Stamler, J.1    Shekelle, R.2
  • 131
    • 0028157335 scopus 로고
    • Membrane. lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form(type I) and demyelination in late-onset form(type II)
    • Svennerholm L, Gottfries CG. 1994. Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form(type I) and demyelination in late-onset form(type II). J Neurochem 62(3):1039-1047.
    • (1994) J. Neurochem. , vol.62 , Issue.3 , pp. 1039-1047
    • Svennerholm, L.1    Gottfries, C.G.2
  • 132
    • 0032507596 scopus 로고    scopus 로고
    • Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells
    • Svensson AL, Nordberg A. 1998. Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells. Neuroreport 9(7):1519-1522.
    • (1998) Neuroreport , vol.9 , Issue.7 , pp. 1519-1522
    • Svensson, A.L.1    Nordberg, A.2
  • 133
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. 2001. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 21(11):1712-1719.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , Issue.11 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 134
    • 3042627230 scopus 로고    scopus 로고
    • Anti-apoptotic effect of atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardiac myocytes through protein kinase C activation
    • Tanaka K, Honda M, Takabatake T. 2004. Anti-apoptotic effect of atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardiac myocytes through protein kinase C activation. Clin Exp Pharmacol Physiol 31(5-6):360-364.
    • (2004) Clin. Exp. Pharmacol. Physiol. , vol.31 , Issue.5-6 , pp. 360-364
    • Tanaka, K.1    Honda, M.2    Takabatake, T.3
  • 136
    • 0000741638 scopus 로고
    • Some quantitative cerebral findings in normal and demented old people
    • Terry RD, editor. New York: Raven Press
    • Tomlinson B, Henderson G. 1976. Some quantitative cerebral findings in normal and demented old people. In: Terry RD, editor. Neurobiology of aging. New York: Raven Press.
    • (1976) Neurobiology of Aging
    • Tomlinson, B.1    Henderson, G.2
  • 137
    • 0000383864 scopus 로고
    • Ageing and the dementias
    • Hume Adams J, Corsellis JAN, Duchen LW, editors. London: Edward Arnold
    • Tomlinson BE, Corsellis JAN. 1984. Ageing and the dementias. In: Hume Adams J, Corsellis JAN, Duchen LW, editors. Greenfield's neuropathology. London: Edward Arnold. p 951-1025.
    • (1984) Greenfield's Neuropathology , pp. 951-1025
    • Tomlinson, B.E.1    Corsellis, J.A.N.2
  • 138
    • 0036674082 scopus 로고    scopus 로고
    • Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway
    • Tun H, Marlow L, Pinnix I, Kinsey R, Sambamurti K. 2002. Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway. J Mol Neurosci 19(1-2):31-35.
    • (2002) J. Mol. Neurosci. , vol.19 , Issue.1-2 , pp. 31-35
    • Tun, H.1    Marlow, L.2    Pinnix, I.3    Kinsey, R.4    Sambamurti, K.5
  • 140
    • 0034609516 scopus 로고    scopus 로고
    • The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain
    • Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ. 2000. The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain. Biochemistry 39(35):10831-10839.
    • (2000) Biochemistry , vol.39 , Issue.35 , pp. 10831-10839
    • Walsh, D.M.1    Tseng, B.P.2    Rydel, R.E.3    Podlisny, M.B.4    Selkoe, D.J.5
  • 142
    • 0000306390 scopus 로고    scopus 로고
    • Statins do more than just lower cholesterol
    • Vaughan CJ, Murphy MB, Buckley BM. 1996. Statins do more than just lower cholesterol. Lancet 348(9034):1079-1082.
    • (1996) Lancet , vol.348 , Issue.9034 , pp. 1079-1082
    • Vaughan, C.J.1    Murphy, M.B.2    Buckley, B.M.3
  • 144
    • 18144435700 scopus 로고    scopus 로고
    • Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys
    • Williams JK, Sukhova GK, Herrington DM, Libby P. 1998. Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys. J Am Coll Cardiol 31(3):684-691.
    • (1998) J. Am. Coll. Cardiol. , vol.31 , Issue.3 , pp. 684-691
    • Williams, J.K.1    Sukhova, G.K.2    Herrington, D.M.3    Libby, P.4
  • 146
    • 0018372161 scopus 로고
    • Alzheimer neurofibrillary tangles in diseases other than senile and presenile dementia
    • Wisniewski K, George A, Moretz R, Wisniewski H. 1979. Alzheimer neurofibrillary tangles in diseases other than senile and presenile dementia. Ann Neurol 5:288-294.
    • (1979) Ann. Neurol. , vol.5 , pp. 288-294
    • Wisniewski, K.1    George, A.2    Moretz, R.3    Wisniewski, H.4
  • 147
    • 0033772113 scopus 로고    scopus 로고
    • Decreased prevalence of alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
    • Wolozin B, Kellman W, Ruosseau P, Celesia GG, Siegel G. 2000. Decreased prevalence of alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57(10):1439-1443.
    • (2000) Arch. Neurol. , vol.57 , Issue.10 , pp. 1439-1443
    • Wolozin, B.1    Kellman, W.2    Ruosseau, P.3    Celesia, G.G.4    Siegel, G.5
  • 148
    • 0038182452 scopus 로고    scopus 로고
    • Brain region-dependent increases in beta-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits
    • Wu CW, Liao PC, Lin C, Kuo CJ, Chen ST, Chen H, Kuo YM. 2003. Brain region-dependent increases in beta-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits. J Neural Transm 110(6):641-649.
    • (2003) J. Neural. Transm. , vol.110 , Issue.6 , pp. 641-649
    • Wu, C.W.1    Liao, P.C.2    Lin, C.3    Kuo, C.J.4    Chen, S.T.5    Chen, H.6    Kuo, Y.M.7
  • 149
    • 0036186663 scopus 로고    scopus 로고
    • Serum lipoprotein levels, statin use, and cognitive function in older women
    • Yaffe K, Barrett-Connor E, Lin F, Grady D. 2002. Serum lipoprotein levels, statin use, and cognitive function in older women. Arch Neurol 59(3):378-384.
    • (2002) Arch. Neurol. , vol.59 , Issue.3 , pp. 378-384
    • Yaffe, K.1    Barrett-Connor, E.2    Lin, F.3    Grady, D.4


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