Apolipoprotein E genotype influences cognitive phenotype' in patients with Alzheimer's disease but not in healthy control subjects

Neurology

Volumn 50, Issue 2, 1998, Pages 355-362

  Smith, Glenn E ^a   Bohac, D L ^a   Waring, S C ^a   Kokmen, E ^a   Tangalos, E G ^a   Ivnik, R J ^a   Petersen, R C ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4;

AGED; ALZHEIMER DISEASE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECALL; SCORING SYSTEM;

EID: 0031911493     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.50.2.355     Document Type: Article

References (46)

1. Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-1981.
2. National Institute on Aging, Alzheimer's Association Working Group. Apolipoprotein E genotyping in Alzheimer's disease. Lancet 1996;347:1091-1095.
3. Tsai M, Tangalos EG, Petersen RC, et al. Apolipoprotein E: Risk factor for Alzheimer's disease. American Journal of Human Genetics 1994;54:643-649.
4. Mayeux R, Stern Y, Ottman R, et al. The Apolipoprotein E4 allele in patients with Alzheimer's disease. Ann Neurol 1993; 34:752-754.
5. Rebeck GW, Reiter JS, Strickland DK, Hyman BT. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 1993;11:575-580.
6. Strittmatter WJ, Saunders AM, Goedert M, et al. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein Tau: implications for Alzheimer's disease. Proc Natl Acad Sci USA 1994;91:11183-11186.
7. Petersen RC, Smith GE, Ivnik RJ, et al. Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals. JAMA 1995;273:1274-1278.
8. Smith GE, Petersen RC, Parisi JE, et al. Definition, course and outcome of mild cognitive impairment. Aging Neuropsychol Cogn 1996;3:141-147.
9. Tierney MC, Szalai JP, Snow WG, et al. Prediction of probable Alzheimer's disease in memory-impaired patients: a prospective longitudinal study. Neurology 1996;46:661-665.
10. Frisoni GB, Govoni S, Geroldi C, et al. Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease. Ann Neurol 1995;37: 596-604.
11. Folstein MF, Folstein SE, McHugh PR. "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
12. Basun H, Grut M, Winblad B, Lannfelt L. Apolipoprotein epsilon 4 allele and disease progression in patients with late-onset Alzheimer's disease. Neurosci Lett 1995;183:32-34.
13. Waring SC, Rocca WA, Smith GE, Tangalos EG, Kokmen E, Petersen RC. Apolipoprotein E and rate of clinical progression in Alzheimer's disease. Neurology 1996;46:A348.
14. Mattis S. Dementia rating scale. Professional manual. Odessa, Fl: Psychological Assessment Resources, 1988.
15. Weintraub S. The Record of Independent Living: an informant-completed measure of activities of daily living and behavior in elderly patients with cognitive impairment. Am J Alzh Care Relat Dis 1986;7:35-39.
16. Bondi MW, Salmon DP, Monsch AU, et al. Episodic memory changes are associated with the apo E-e4 allele in nondemented older adults. Neurology 1995;45:2203-2206.
17. Jacobs D, Stern Y, Tycko B, Maestre G, Mayeux R. Apolipoprotein-E and cognitive function in nondemented older adults. J Int Neuropsychol Soc 1995;1:131.
18. Reed T, Carmelli D, Swan GE, et al. Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E e4 allele. Arch Neurol 1994;51:1189-1192.
19. Rebeck GW, Perls TT, West HL, Sodhi P, Lipsitz LA, Hyman BT. Reduced apolipoprotein E4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals. Neurology 1994;44:1513-1516.
20. Waring SC, Rocca WA, Schaid DJ, et al. Apolipoprotein E and Alzheimer's disease: trends in risk by age at onset. Ann Neurol 1995;38:324.
21. Flicker C, Ferris SH, Reisberg B. Mild cognitive impairment in the elderly: predictors of dementia. Neurology 1991;41: 1006-1009.
22. Petersen RC, Kokmen E, Tangalos E, Ivnik RJ, Kurland LT. Mayo Clinic Alzheimer's Disease Patient Registry. Aging 1990;2:408-415.
23. Kokmen E, Naessens JM, Offord KP. A short test of mental status: description and preliminary results. Mayo Clin Proc 1987;62:281-288.
24. Hachinski VC, Iliff LD, Zilhka E, et al. Cerebral blood flow in dementia. Arch Neurol 1975;32:632-637.
25. Sheikh JI, Yesavage JA. Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. In: Brink TL, ed. Clinical gerontology: a guide to assessment and intervention. New York: Haworth Press, 1986:165-173.
26. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 3rd ed., revised. Washington, DC: American Psychiatric Association, 1987.
27. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
28. Ivnik RJ, Malec JF, Smith GE, et al. Mayo's older Americans normative studies: WAIS-R, WMS-R and AVLT norms for ages 56 through 97. Clin Neuropsychol 1992;6(suppl):1-104.
29. Hixon JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplication and cleavage with Hha I. J Lipid Res 1990;31:545-548.
30. Smith GE, Ivnik RJ, Malec JF, Petersen RC, Kokmen E, Tangalos EG. Mayo Cognitive Factor Scales: derivation of a short battery and norms for factor scores. Neuropsychology 1994;8: 194-202.
31. Wechsler DA. Wechsler Adult Intelligence Scale-revised. New York: Psychological Corporation, 1981.
32. Wechsler DA. Wechsler Memory Scale-revised. New York: Psychological Corporation, 1987.
33. Rey A. L'examen clinique en psychologie. Paris: Presses Universitaires de France, 1964.
34. Smith GE, Ivnik RJ, Malec JF, Petersen RC, Tangalos EG, Kurland LT. Mayo's Older Americans Normative Studies (MOANS): factor structure of a core battery. Psychol Assess JCCP 1992;4:382-390.
35. Smith GE, Ivnik RJ, Malec JF, Tangalos EG. Factor structure of the MOANS core battery: replication in a clinical sample. Psychol Assess JCCP 1993;5:121-124.
36. Ivnik RJ, Malec JF, Smith GE, Tangalos EG, Petersen RC. Neuropsychological tests' norms above age 55: COWAT, BNT, MAE Token, WRAT-R Reading, AMNART, STROOP, TMT and JLO. Clin Neuropsychol 1996;10:262-278.
37. Kaplan EF, Goodglass H, Weintraub S. The Boston Naming Test. Boston: E. Kaplan & H. Goodglass, 1978.
38. Petersen RC, Jack CR Jr, Smith GE, Kokmen E, Ivnik RJ, Tangalos EG. MR volumetric dissociation of memory and naming in Alzheimer's disease. Neurology 1994;44:209S.
39. Welsh K, Butters N, Hughes J, Mohs R, Heyman A. Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures. Arch Neurol 1991;48:278-281.
40. Masur DM, Sliwinski M, Lipton RB, Blau AD, Crystal HA. Neuropsychological prediction of dementia and the absence of dementia in healthy elderly persons. Neurology 1994;44:1427-1432.
41. Ivnik RJ, Malec JF, Smith GE, et al. Mayo's Older Americans Normative Studies: updated AVLT norms for ages 56 to 97. Clin Neuropsychol 1992;6(suppl):83-104.
42. Poirier J. Neurobiology of apolipoprotein E in the normal brain and in Alzheimer's disease. In: Iqbal K, Winblad B, Nishimura T, Takeda M, Wisniewski HM, eds. Alzheimer's disease: biology, diagnosis and therapeutics. West Sussex, England: John Wiley & Sons, 1997:93-101.
43. Monsch AU, Bondi MW, Butters N, et al. A comparison of category and letter fluency in Alzheimer's disease and Huntington's disease. Neuropsychology 1994;8:25-30.
44. Lemsky CM, Smith GE, Malec JF, Ivnik RJ. Identifying risk for functional impairment using cognitive measures: an application of CART modeling. Neuropsychology 1996;10:368-375.
45. Arnold SE, Hyman BT, Flory J, Damasio AR, VanHoesen GW. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cerebr Cortex 1991;1:103-116.
46. Roses AD. The predictive value of APOE genotyping in the early diagnosis of dementia of the Alzheimer type: data from three independent series. In: Iqbal K, Winblad B, Nishimura T, Takeda M, Wisniewski HM, eds. Alzheimer's disease: biology, diagnosis and therapeutics. West Sussex, England: John Wiley & Sons, 1997:85-91.