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Volumn 87, Issue 2, 1996, Pages 263-276

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

Author keywords

[No Author keywords available]

Indexed keywords

BETA FRUCTOFURANOSIDASE; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; RAG1 PROTEIN; RAG2 PROTEIN; UNCLASSIFIED DRUG;

EID: 0030592523     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81344-6     Document Type: Article
Times cited : (205)

References (57)
  • 3
    • 0029886929 scopus 로고    scopus 로고
    • Mechanism of V(D)J recombination
    • Bogue, M., and Roth, D.B. (1996). Mechanism of V(D)J recombination. Curr. Opin. Immunol. 8, 175-180.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 175-180
    • Bogue, M.1    Roth, D.B.2
  • 4
    • 0027373797 scopus 로고
    • Lactose repressor-operator DNA interactions: Kinetic analysis by a surface plasmon resonance biosensor
    • Bondeson, K.A., Frostell-Karlsson, A.F., Fagerstam, L., and Magnusson, G. (1993). Lactose repressor-operator DNA interactions: kinetic analysis by a surface plasmon resonance biosensor. Anal. Biochem. 214, 245-251.
    • (1993) Anal. Biochem. , vol.214 , pp. 245-251
    • Bondeson, K.A.1    Frostell-Karlsson, A.F.2    Fagerstam, L.3    Magnusson, G.4
  • 5
    • 0025811882 scopus 로고
    • The SCID mouse mutant: Definition, characterization, and potential uses
    • Bosma, M.J., and Carroll, A.M. (1991). The SCID mouse mutant: definition, characterization, and potential uses. Annu. Rev. Immunol. 9, 323-350.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 323-350
    • Bosma, M.J.1    Carroll, A.M.2
  • 6
    • 0024236673 scopus 로고
    • The mechanism of conservative site-specific recombination
    • Craig, N.L. (1988). The mechanism of conservative site-specific recombination. Annu. Rev. Genet. 22, 77-105.
    • (1988) Annu. Rev. Genet. , vol.22 , pp. 77-105
    • Craig, N.L.1
  • 7
    • 0028307661 scopus 로고
    • Analysis of regions of Rag-2 important for V(D)J recombination
    • Cuomo, C.A., and Oettinger, M.A. (1994). Analysis of regions of Rag-2 important for V(D)J recombination. Nucl. Acids Res. 10, 1810-1814.
    • (1994) Nucl. Acids Res. , vol.10 , pp. 1810-1814
    • Cuomo, C.A.1    Oettinger, M.A.2
  • 8
    • 0026784161 scopus 로고
    • Binding of IS903 transposase to its inverted repeat in vitro
    • Derbyshire, K.M., and Grindley, N.D. (1992). Binding of IS903 transposase to its inverted repeat in vitro. EMBO J. 11, 3449-3455.
    • (1992) EMBO J. , vol.11 , pp. 3449-3455
    • Derbyshire, K.M.1    Grindley, N.D.2
  • 9
    • 0001265782 scopus 로고    scopus 로고
    • Rag-1 mediates signal sequence recognition and recruitment of Rag-2 in V(D)J recombination
    • this issue
    • Difilippantonio, M.J., McMahan, C.J., Eastman, Q.M., Spanopoulou, E., and Schatz, D.G. (1996). Rag-1 mediates signal sequence recognition and recruitment of Rag-2 in V(D)J recombination. Cell 87, this issue.
    • (1996) Cell , vol.87
    • Difilippantonio, M.J.1    McMahan, C.J.2    Eastman, Q.M.3    Spanopoulou, E.4    Schatz, D.G.5
  • 10
    • 0026704685 scopus 로고
    • Evidence suggesting an evolutionary relationship between transposable elements and immune system recombination sequences
    • Dreyfus, D.H. (1992). Evidence suggesting an evolutionary relationship between transposable elements and immune system recombination sequences. Mol. Immunol. 29, 807-810.
    • (1992) Mol. Immunol. , vol.29 , pp. 807-810
    • Dreyfus, D.H.1
  • 11
    • 0029864993 scopus 로고    scopus 로고
    • Initiation of V(D)J recombination in vitro obeying the 12/23 rule
    • Eastman, Q.M., Leu, T.M.J., and Schatz, D.G. (1996). Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature 380, 85-88.
    • (1996) Nature , vol.380 , pp. 85-88
    • Eastman, Q.M.1    Leu, T.M.J.2    Schatz, D.G.3
  • 12
    • 0028118764 scopus 로고
    • Hin recombinase bound to DNA: The origin of specificity in major and minor groove interactions
    • Feng, J.A., Johnson, R.C., and Dickerson, R.E. (1994). Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions. Science 263, 348-355.
    • (1994) Science , vol.263 , pp. 348-355
    • Feng, J.A.1    Johnson, R.C.2    Dickerson, R.E.3
  • 13
    • 0028269682 scopus 로고
    • Real-time DNA binding measurements of the ETSL recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms
    • Fisher, R.J., Fluash, M., Casa-Finet, J., Erckson, J.W., Kondoh, A., Bladen, S.V., Fisher, C., Watson, D.K., and Papas, T. (1994). Real-time DNA binding measurements of the ETSL recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms. Protein Sci. 3, 257-266.
    • (1994) Protein Sci. , vol.3 , pp. 257-266
    • Fisher, R.J.1    Fluash, M.2    Casa-Finet, J.3    Erckson, J.W.4    Kondoh, A.5    Bladen, S.V.6    Fisher, C.7    Watson, D.K.8    Papas, T.9
  • 14
    • 0025011134 scopus 로고
    • The scid mutation in mice causes a general defect in DNA repair
    • Fulop, G.M., and Philips, R.A. (1990). The scid mutation in mice causes a general defect in DNA repair. Nature 347, 479-482.
    • (1990) Nature , vol.347 , pp. 479-482
    • Fulop, G.M.1    Philips, R.A.2
  • 17
    • 0028990214 scopus 로고
    • The recombination activating gene 1 (Rag1) of rainbow trout (Oncorhynchus mykiss): Cloning, expression and phylogenetic analysis
    • Hansen, J.D., and Kaattari, S.L. (1995). The recombination activating gene 1 (Rag1) of rainbow trout (Oncorhynchus mykiss): cloning, expression and phylogenetic analysis. Immunogenetics 42, 188-195.
    • (1995) Immunogenetics , vol.42 , pp. 188-195
    • Hansen, J.D.1    Kaattari, S.L.2
  • 18
    • 0023659483 scopus 로고
    • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V(D)J signals
    • Hesse, J.E., Lieber, M.R., Gellert, M., and Mizuuchi, K. (1987). Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V(D)J signals. Cell 49, 775-783.
    • (1987) Cell , vol.49 , pp. 775-783
    • Hesse, J.E.1    Lieber, M.R.2    Gellert, M.3    Mizuuchi, K.4
  • 19
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • Hesse, J.E., Lieber, M.R., Mizuuchi, K., and Gellert, M. (1989). V(D)J recombination: a functional definition of the joining signals. Genes Dev. 3, 1053-1061.
    • (1989) Genes Dev. , vol.3 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 20
    • 0026748747 scopus 로고
    • Sequence-specific interaction of the Salmonella Hin recombinase in both major and minor grooves of DNA
    • Hughes, K.T., Gaines, P.C.W., Karlinsey, J.E., Vinayak, R., and Simon, M.I. (1992). Sequence-specific interaction of the Salmonella Hin recombinase in both major and minor grooves of DNA. EMBO J. 11, 2695-2705.
    • (1992) EMBO J. , vol.11 , pp. 2695-2705
    • Hughes, K.T.1    Gaines, P.C.W.2    Karlinsey, J.E.3    Vinayak, R.4    Simon, M.I.5
  • 21
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J recombination
    • Jackson, S.P., and Jeggo, P.A. (1995). DNA double-strand break repair and V(D)J recombination. Trends Biochem. Sci. 20, 412-415.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 23
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological and comparative analyses
    • Lewis, S.M. (1994). The mechanism of V(D)J joining: lessons from molecular, immunological and comparative analyses. Adv. Immunol. 56, 27-150.
    • (1994) Adv. Immunol. , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 25
    • 0025836948 scopus 로고
    • Site-specific recombination in the immune system
    • Lieber, M.R. (1991). Site-specific recombination in the immune system. FASEB J. 5, 2934-2944.
    • (1991) FASEB J. , vol.5 , pp. 2934-2944
    • Lieber, M.R.1
  • 28
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger, M.A., Schatz, D.G., Gorka, C., and Baltimore, D. (1990). RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 248, 1517-1523.
    • (1990) Science , vol.248 , pp. 1517-1523
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 30
    • 0027245559 scopus 로고
    • V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
    • Pergola, F., Zdzienicka, M.Z., and Lieber, M.R. (1993). V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol Cell. Biol. 13, 3464-3471.
    • (1993) Mol Cell. Biol. , vol.13 , pp. 3464-3471
    • Pergola, F.1    Zdzienicka, M.Z.2    Lieber, M.R.3
  • 31
    • 0028291092 scopus 로고
    • Conservation of sequence in recombination signal sequence spacers
    • Ramsden, D.A., Baetz, K., and Wu, G.E. (1994). Conservation of sequence in recombination signal sequence spacers. Nucl. Acids Res. 22, 1785-1796.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 1785-1796
    • Ramsden, D.A.1    Baetz, K.2    Wu, G.E.3
  • 32
    • 0029891597 scopus 로고    scopus 로고
    • Distinct DNA sequence and structure requirements forthe two steps of V(D)J recombination signal cleavage
    • Ramsden, D.A., McBlane, J.F., van Gent, D.C., and Gellert, M. (1996). Distinct DNA sequence and structure requirements forthe two steps of V(D)J recombination signal cleavage. EMBO J. 15, 3197-3206.
    • (1996) EMBO J. , vol.15 , pp. 3197-3206
    • Ramsden, D.A.1    McBlane, J.F.2    Van Gent, D.C.3    Gellert, M.4
  • 33
    • 0002819749 scopus 로고
    • Conservation of sequences necessary for V gene recombination
    • G. Kelsoe and D.H. Shultze, eds. (New York: Academic Press)
    • Rathbun, G.A., and Tucker, P.W. (1987). Conservation of sequences necessary for V gene recombination. In Evolution and Vertebrate Immunity: The Antigen Receptor and MHC Families, G. Kelsoe and D.H. Shultze, eds. (New York: Academic Press), pp. 85-115.
    • (1987) Evolution and Vertebrate Immunity: The Antigen Receptor and MHC Families , pp. 85-115
    • Rathbun, G.A.1    Tucker, P.W.2
  • 34
    • 0029966374 scopus 로고    scopus 로고
    • Genetic evidence that the Rag-1 protein directly participates in V(D)J recombination through substrate recognition
    • Roman, C.A.J., and Baltimore, D. (1996). Genetic evidence that the Rag-1 protein directly participates in V(D)J recombination through substrate recognition. Proc. Natl. Acad. Sci. USA 93, 2333-2338.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2333-2338
    • Roman, C.A.J.1    Baltimore, D.2
  • 35
    • 0026792892 scopus 로고
    • V(D)J recombination: Covalently sealed (hairpin) coding ends in scid mouse thymocytes
    • Roth, D.B., Menetski, J.P., Nakajima, P.M., Bosma, M.J., and Gellert, M. (1992). V(D)J recombination: covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell 70, 983-991.
    • (1992) Cell , vol.70 , pp. 983-991
    • Roth, D.B.1    Menetski, J.P.2    Nakajima, P.M.3    Bosma, M.J.4    Gellert, M.5
  • 36
    • 0027770854 scopus 로고
    • Expression and V(D)J recombination activity of mutated Rag-1 proteins
    • Sadofsky, M.J., Hesse, J.E., McBlane, J.F., and Gellert, M. (1993). Expression and V(D)J recombination activity of mutated Rag-1 proteins. Nucl. Acids Res. 21, 5644-5650.
    • (1993) Nucl. Acids Res. , vol.21 , pp. 5644-5650
    • Sadofsky, M.J.1    Hesse, J.E.2    McBlane, J.F.3    Gellert, M.4
  • 37
    • 0028237683 scopus 로고
    • Definition of a core region of Rag-2 that is functional in V(D)J recombination
    • Sadofsky, M., Hesse, J.E., and Gellert, M. (1994). Definition of a core region of Rag-2 that is functional in V(D)J recombination. Nucl. Acids Res. 22, 1805-1809.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 1805-1809
    • Sadofsky, M.1    Hesse, J.E.2    Gellert, M.3
  • 38
    • 0029092358 scopus 로고
    • Rag-1 mutations that affect the target specificity of V(D)J recombination: A possible direct role of Rag-1 in site recognition
    • Sadofsky, M.J., Hesse, J.E., van Gent, D.C., and Gellert, M. (1995). Rag-1 mutations that affect the target specificity of V(D)J recombination: a possible direct role of Rag-1 in site recognition. Genes Dev. 9, 2193-2199.
    • (1995) Genes Dev. , vol.9 , pp. 2193-2199
    • Sadofsky, M.J.1    Hesse, J.E.2    Van Gent, D.C.3    Gellert, M.4
  • 39
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene RAG-1
    • Schatz, D., Oettinger, M.A., and Baltimore, D. (1989). The V(D)J recombination activating gene RAG-1. Cell 59, 1035-1048.
    • (1989) Cell , vol.59 , pp. 1035-1048
    • Schatz, D.1    Oettinger, M.A.2    Baltimore, D.3
  • 40
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., Constantinescu, A., Morrow, T., Baxter, M., and Beug, A. (1993). Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 7, 2520-2532.
    • (1993) Genes Dev. , vol.7 , pp. 2520-2532
    • Schlissel, M.1    Constantinescu, A.2    Morrow, T.3    Baxter, M.4    Beug, A.5
  • 43
    • 0027197151 scopus 로고
    • Dispensable sequence motifs in the Rag-1 and Rag-2 genes for plasmid V(D)J recombination
    • Silver, D.P., Spanopoulou, E., Mulligan, R.C., and Baltimore, D. (1993). Dispensable sequence motifs in the Rag-1 and Rag-2 genes for plasmid V(D)J recombination. Proc. Natl. Acad. Sci. USA 90, 6100-6104.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6100-6104
    • Silver, D.P.1    Spanopoulou, E.2    Mulligan, R.C.3    Baltimore, D.4
  • 44
    • 0030512103 scopus 로고    scopus 로고
    • Cellular and molecular analysis of lymphoid development using Rag-deficient mice
    • Spanopoulou, E. (1996). Cellular and molecular analysis of lymphoid development using Rag-deficient mice. Int. Rev. Immunol. 13, 257-288.
    • (1996) Int. Rev. Immunol. , vol.13 , pp. 257-288
    • Spanopoulou, E.1
  • 46
    • 0029553231 scopus 로고
    • Localization, interaction, and RNA-binding properties of the V(D)J recombination activating proteins Rag-1 and Rag-2
    • Spanopoulou, E., Cortes, P., Huang, E., Shih, C., Silver, D., Svec, P., and Baltimore, D. (1995). Localization, interaction, and RNA-binding properties of the V(D)J recombination activating proteins Rag-1 and Rag-2. Immunity 3, 715-726.
    • (1995) Immunity , vol.3 , pp. 715-726
    • Spanopoulou, E.1    Cortes, P.2    Huang, E.3    Shih, C.4    Silver, D.5    Svec, P.6    Baltimore, D.7
  • 47
    • 0027156278 scopus 로고
    • Impairment of V(D)J recombination in double strand break mutants
    • Taccioli, G.E., Rathbun, G., Oltz, E., Stamato, T., Jeggo, P.A., and Alt, F.W. (1993). Impairment of V(D)J recombination in double strand break mutants. Science 260, 207-210.
    • (1993) Science , vol.260 , pp. 207-210
    • Taccioli, G.E.1    Rathbun, G.2    Oltz, E.3    Stamato, T.4    Jeggo, P.A.5    Alt, F.W.6
  • 48
    • 0028867419 scopus 로고
    • New insights into V(D)J recombination and its role in the evolution of the immune system
    • Thompson, C.B. (1995). New insights into V(D)J recombination and its role in the evolution of the immune system. Immunity 3, 531-539.
    • (1995) Immunity , vol.3 , pp. 531-539
    • Thompson, C.B.1
  • 49
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. (1983). Somatic generation of antibody diversity. Nature 302, 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 51
    • 0030009253 scopus 로고    scopus 로고
    • The Rag-1 and Rag-2 proteins establish the 12/23 rule in V(D)J recombination
    • van Gent, D.C., Ramsden, D.A., and Gellert, M. (1996a). The Rag-1 and Rag-2 proteins establish the 12/23 rule in V(D)J recombination. Cell 85, 107-114.
    • (1996) Cell , vol.85 , pp. 107-114
    • Van Gent, D.C.1    Ramsden, D.A.2    Gellert, M.3
  • 52
    • 0029967722 scopus 로고    scopus 로고
    • Similarities between initiation of V(D)J recombination and retroviral integration
    • van Gent, D.C., Mizuuchi, K., and Gellert, M. (1996b). Similarities between initiation of V(D)J recombination and retroviral integration. Science 271, 1592-1594.
    • (1996) Science , vol.271 , pp. 1592-1594
    • Van Gent, D.C.1    Mizuuchi, K.2    Gellert, M.3
  • 53
    • 0028598507 scopus 로고
    • Tc1 transposase of Caenorhabditis elegans is an endonuclease with a bipartite DNA binding domain
    • Vos, J.C., and Plasterk, R.H.A. (1994). Tc1 transposase of Caenorhabditis elegans is an endonuclease with a bipartite DNA binding domain. EMBO J. 13, 6125-6132.
    • (1994) EMBO J. , vol.13 , pp. 6125-6132
    • Vos, J.C.1    Plasterk, R.H.A.2
  • 54
    • 0027321357 scopus 로고
    • Characterization of the Caenorhabditis elegans Tc1 transposase in vivo and in vitro
    • Vos, J.C., van Luenen, H.G.A.M., and Plasterk, R.H.A. (1993). Characterization of the Caenorhabditis elegans Tc1 transposase in vivo and in vitro. Genes Dev. 7, 1244-1253.
    • (1993) Genes Dev. , vol.7 , pp. 1244-1253
    • Vos, J.C.1    Van Luenen, H.G.A.M.2    Plasterk, R.H.A.3
  • 55
    • 0028035559 scopus 로고
    • Homeotic genes seek partners
    • White, R. (1994). Homeotic genes seek partners. Curr. Biol. 4, 48-50.
    • (1994) Curr. Biol. , vol.4 , pp. 48-50
    • White, R.1
  • 56
    • 0028919759 scopus 로고
    • Crystal structure of a paired domain-DNA complex at 2.5 Å resolution reveals structure basis for Pax developmental mutations
    • Xu, W., Rould, M.A., Jun, S., Desplan, C., and Pabo, C.O. (1995). Crystal structure of a paired domain-DNA complex at 2.5 Å resolution reveals structure basis for Pax developmental mutations. Cell 80, 639-650.
    • (1995) Cell , vol.80 , pp. 639-650
    • Xu, W.1    Rould, M.A.2    Jun, S.3    Desplan, C.4    Pabo, C.O.5
  • 57
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu, C., Bogue, M.A., Lim, D.-S., Hasty, P., and Roth, D.B. (1996). Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379-390.
    • (1996) Cell , vol.86 , pp. 379-390
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.