메뉴 건너뛰기




Volumn 222, Issue 1, 2005, Pages 1-10

Wnt signaling in lung cancer

Author keywords

APC; Beta catenin; Dishevelled; Lung cancer; sFRP; WIF; Wnt

Indexed keywords

APC PROTEIN; BETA CATENIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1; WNT PROTEIN; WNT1 PROTEIN; WNT2 PROTEIN; WNT7A PROTEIN;

EID: 17444419037     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.08.040     Document Type: Review
Times cited : (232)

References (102)
  • 1
    • 2342549269 scopus 로고    scopus 로고
    • The care of the lung cancer patient in the 21st century: A new age
    • W. Smith, and F.R. Khuri The care of the lung cancer patient in the 21st century: a new age Semin. Oncol. 31 2004 11 15
    • (2004) Semin. Oncol. , vol.31 , pp. 11-15
    • Smith, W.1    Khuri, F.R.2
  • 2
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • R. Nusse, and H.E. Varmus Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome Cell 31 1982 99 109
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 3
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • M. Bienz, and H. Clevers Linking colorectal cancer to Wnt signaling Cell 103 2000 311 320
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 4
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • P. Polakis Wnt signaling and cancer Genes Dev. 14 2000 1837 1851
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 5
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, and B. Vogelstein Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC Science 275 1997 1787 1790
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6
  • 6
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/-colon carcinoma
    • V. Korinek, N. Barker, P.J. Morin, D. Van Wichen, R. de Weger, and K.W. Kinzler Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/-colon carcinoma Science 275 1997 1784 1787
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3    Van Wichen, D.4    De Weger, R.5    Kinzler, K.W.6
  • 7
    • 0037179894 scopus 로고    scopus 로고
    • Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
    • C.S. Rhee, M. Sen, D. Lu, C. Wu, L. Leoni, and J. Rubin Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas Oncogene 21 2002 6598 6605
    • (2002) Oncogene , vol.21 , pp. 6598-6605
    • Rhee, C.S.1    Sen, M.2    Lu, D.3    Wu, C.4    Leoni, L.5    Rubin, J.6
  • 10
    • 0037778008 scopus 로고    scopus 로고
    • The Wnt signaling pathway and its role in tumor development
    • B. Lustig, and J. Behrens The Wnt signaling pathway and its role in tumor development J. Cancer Res. Clin. Oncol. 129 2003 199 221
    • (2003) J. Cancer Res. Clin. Oncol. , vol.129 , pp. 199-221
    • Lustig, B.1    Behrens, J.2
  • 11
    • 0037309239 scopus 로고    scopus 로고
    • You Wnt some, you lose some: Oncogenes in the Wnt signaling pathway
    • J.H. Van Es, N. Barker, and H. Clevers You Wnt some, you lose some: oncogenes in the Wnt signaling pathway Curr. Opin. Genet. Dev. 13 2003 28 33
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 28-33
    • Van Es, J.H.1    Barker, N.2    Clevers, H.3
  • 13
    • 0032941717 scopus 로고    scopus 로고
    • Regulation of LEF-1/TCF transcription factors by Wnt and other signals
    • Q. Eastman, and R. Grosschedl Regulation of LEF-1/TCF transcription factors by Wnt and other signals Curr. Opin. Cell Biol. 11 1999 233 240
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 233-240
    • Eastman, Q.1    Grosschedl, R.2
  • 14
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling
    • M.T. Veeman, J.D. Axelrod, and R.T. Moon A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling Dev. Cell 5 2003 367 377
    • (2003) Dev. Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 15
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • V. Korinek, N. Barker, P. Moerer, E. van Donselaar, G. Huls, and P.J. Peters Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 Nat. Genet. 19 1998 379 383
    • (1998) Nat. Genet. , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3    Van Donselaar, E.4    Huls, G.5    Peters, P.J.6
  • 17
    • 0037043688 scopus 로고    scopus 로고
    • Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis
    • P. Pandur, M. Lasche, L.M. Eisenberg, and M. Kuhl Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis Nature 418 2002 636 641
    • (2002) Nature , vol.418 , pp. 636-641
    • Pandur, P.1    Lasche, M.2    Eisenberg, L.M.3    Kuhl, M.4
  • 18
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • T. Reya, A.W. Duncan, L. Ailles, J. Domen, D.C. Scherer, and K. Willert A role for Wnt signalling in self-renewal of haematopoietic stem cells Nature 423 2003 409 414
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3    Domen, J.4    Scherer, D.C.5    Willert, K.6
  • 19
    • 0023653232 scopus 로고
    • The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
    • F. Rijsewijk, M. Schuermann, E. Wagenaar, P. Parren, D. Weigel, and R. Nusse The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless Cell 50 1987 649 657
    • (1987) Cell , vol.50 , pp. 649-657
    • Rijsewijk, F.1    Schuermann, M.2    Wagenaar, E.3    Parren, P.4    Weigel, D.5    Nusse, R.6
  • 20
    • 0037408422 scopus 로고    scopus 로고
    • Wnt signaling and pulmonary fibrosis
    • E.E. Morrisey Wnt signaling and pulmonary fibrosis Am. J. Pathol. 162 2003 1393 1397
    • (2003) Am. J. Pathol. , vol.162 , pp. 1393-1397
    • Morrisey, E.E.1
  • 21
    • 0032938813 scopus 로고    scopus 로고
    • A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
    • T.P. Yamaguchi, A. Bradley, A.P. McMahon, and S. Jones A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo Development 126 1999 1211 1223
    • (1999) Development , vol.126 , pp. 1211-1223
    • Yamaguchi, T.P.1    Bradley, A.2    McMahon, A.P.3    Jones, S.4
  • 22
    • 0037036408 scopus 로고    scopus 로고
    • The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium
    • J. Weidenfeld, W. Shu, L. Zhang, S.E. Millar, and E.E. Morrisey The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium J. Biol. Chem. 277 2002 21061 21070
    • (2002) J. Biol. Chem. , vol.277 , pp. 21061-21070
    • Weidenfeld, J.1    Shu, W.2    Zhang, L.3    Millar, S.E.4    Morrisey, E.E.5
  • 23
    • 0036056189 scopus 로고    scopus 로고
    • Wnt5a participates in distal lung morphogenesis
    • C. Li, J. Xiao, K. Hormi, Z. Borok, and P. Minoo Wnt5a participates in distal lung morphogenesis Dev. Biol. 248 2002 68 81
    • (2002) Dev. Biol. , vol.248 , pp. 68-81
    • Li, C.1    Xiao, J.2    Hormi, K.3    Borok, Z.4    Minoo, P.5
  • 24
    • 0036802645 scopus 로고    scopus 로고
    • Wnt7b regulates mesenchymal proliferation and vascular development in the lung
    • W. Shu, Y.Q. Jiang, M.M. Lu, and E.E. Morrisey Wnt7b regulates mesenchymal proliferation and vascular development in the lung Development 129 2002 4831 4842
    • (2002) Development , vol.129 , pp. 4831-4842
    • Shu, W.1    Jiang, Y.Q.2    Lu, M.M.3    Morrisey, E.E.4
  • 25
    • 0037531706 scopus 로고    scopus 로고
    • Gene expression signatures identify novel regulatory pathways during murine lung development: Implications for lung tumorigenesis
    • A.E. Bonner, W.J. Lemon, and M. You Gene expression signatures identify novel regulatory pathways during murine lung development: implications for lung tumorigenesis J. Med. Genet. 40 2003 408 417
    • (2003) J. Med. Genet. , vol.40 , pp. 408-417
    • Bonner, A.E.1    Lemon, W.J.2    You, M.3
  • 26
    • 0242500879 scopus 로고    scopus 로고
    • Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
    • M. Chilosi, V. Poletti, A. Zamo, M. Lestani, L. Montagna, and P. Piccoli Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis Am. J. Pathol. 162 2003 1495 1502
    • (2003) Am. J. Pathol. , vol.162 , pp. 1495-1502
    • Chilosi, M.1    Poletti, V.2    Zamo, A.3    Lestani, M.4    Montagna, L.5    Piccoli, P.6
  • 27
    • 3042740437 scopus 로고    scopus 로고
    • From stem cells to cancer: Balancing immortality and neoplasia
    • W.N. Keith From stem cells to cancer: balancing immortality and neoplasia Oncogene 23 2004 5092 5094
    • (2004) Oncogene , vol.23 , pp. 5092-5094
    • Keith, W.N.1
  • 28
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • N. Sato, L. Meijer, L. Skaltsounis, P. Greengard, and A.H. Brivanlou Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor Nat. Med. 10 2004 55 63
    • (2004) Nat. Med. , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 30
    • 0032567078 scopus 로고    scopus 로고
    • De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • U. Gat, R. DasGupta, L. Degenstein, and E. Fuchs De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin Cell 95 1998 605 614
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    Dasgupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 31
    • 18644373146 scopus 로고    scopus 로고
    • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • M. van de Wetering, E. Sancho, C. Verweij, W. de Lau, I. Oving, and A. Hurlstone The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 111 2002 241 250
    • (2002) Cell , vol.111 , pp. 241-250
    • Van De Wetering, M.1    Sancho, E.2    Verweij, C.3    De Lau, W.4    Oving, I.5    Hurlstone, A.6
  • 32
    • 0043215023 scopus 로고    scopus 로고
    • Expression and regulation of WNT1 in human cancer: Up-regulation of WNT1 by beta-estradiol in MCF-7 cells
    • M. Katoh Expression and regulation of WNT1 in human cancer: up-regulation of WNT1 by beta-estradiol in MCF-7 cells Int. J. Oncol. 22 2003 209 212
    • (2003) Int. J. Oncol. , vol.22 , pp. 209-212
    • Katoh, M.1
  • 33
    • 0036154038 scopus 로고    scopus 로고
    • Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours
    • S.C. Wong, S.F. Lo, K.C. Lee, J.W. Yam, J.K. Chan, and W.L. Wendy Hsiao Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours J. Pathol. 196 2002 145 153
    • (2002) J. Pathol. , vol.196 , pp. 145-153
    • Wong, S.C.1    Lo, S.F.2    Lee, K.C.3    Yam, J.W.4    Chan, J.K.5    Wendy Hsiao, W.L.6
  • 34
    • 0035825119 scopus 로고    scopus 로고
    • Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription
    • S. Chen, D.C. Guttridge, Z. You, Z. Zhang, A. Fribley, and M.W. Mayo Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription J. Cell Biol. 152 2001 87 96
    • (2001) J. Cell Biol. , vol.152 , pp. 87-96
    • Chen, S.1    Guttridge, D.C.2    You, Z.3    Zhang, Z.4    Fribley, A.5    Mayo, M.W.6
  • 35
    • 1642341682 scopus 로고    scopus 로고
    • A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells
    • B. He, L. You, K. Uematsu, Z. Xu, A.Y. Lee, and M. Matsangou A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells Neoplasia 6 2004 7 14
    • (2004) Neoplasia , vol.6 , pp. 7-14
    • He, B.1    You, L.2    Uematsu, K.3    Xu, Z.4    Lee, A.Y.5    Matsangou, M.6
  • 36
    • 0035513435 scopus 로고    scopus 로고
    • Frequent up-regulation of WNT2 in primary gastric cancer and colorectal cancer
    • M. Katoh Frequent up-regulation of WNT2 in primary gastric cancer and colorectal cancer Int. J. Oncol. 19 2001 1003 1007
    • (2001) Int. J. Oncol. , vol.19 , pp. 1003-1007
    • Katoh, M.1
  • 37
    • 0024043519 scopus 로고
    • Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancer
    • M.C. Yoshida, M. Wada, H. Satoh, T. Yoshida, H. Sakamoto, and K. Miyagawa Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancer Proc. Natl Acad. Sci. USA 85 1988 4861 4864
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 4861-4864
    • Yoshida, M.C.1    Wada, M.2    Satoh, H.3    Yoshida, T.4    Sakamoto, H.5    Miyagawa, K.6
  • 38
    • 0026549691 scopus 로고
    • Amplification and proviral activation of several Wnt genes during progression and clonal variation of mouse mammary tumors
    • H. Roelink, E. Wagenaar, and R. Nusse Amplification and proviral activation of several Wnt genes during progression and clonal variation of mouse mammary tumors Oncogene 7 1992 487 492
    • (1992) Oncogene , vol.7 , pp. 487-492
    • Roelink, H.1    Wagenaar, E.2    Nusse, R.3
  • 39
    • 0031735293 scopus 로고    scopus 로고
    • Mapping of chromosomal imbalances in gastric adenocarcinoma revealed amplified protooncogenes MYCN, MET, WNT2, and ERBB2
    • M. Nessling, S. Solinas-Toldo, K.K. Wilgenbus, F. Borchard, and P. Lichter Mapping of chromosomal imbalances in gastric adenocarcinoma revealed amplified protooncogenes MYCN, MET, WNT2, and ERBB2 Genes Chromosomes Cancer 23 1998 307 316
    • (1998) Genes Chromosomes Cancer , vol.23 , pp. 307-316
    • Nessling, M.1    Solinas-Toldo, S.2    Wilgenbus, K.K.3    Borchard, F.4    Lichter, P.5
  • 40
    • 0035930967 scopus 로고    scopus 로고
    • WNT2B2 mRNA, up-regulated in primary gastric cancer, is a positive regulator of the WNT-beta-catenin-TCF signaling pathway
    • M. Katoh, H. Kirikoshi, H. Terasaki, and K. Shiokawa WNT2B2 mRNA, up-regulated in primary gastric cancer, is a positive regulator of the WNT-beta-catenin-TCF signaling pathway Biochem. Biophys. Res. Commun. 289 2001 1093 1098
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 1093-1098
    • Katoh, M.1    Kirikoshi, H.2    Terasaki, H.3    Shiokawa, K.4
  • 41
    • 9044224393 scopus 로고    scopus 로고
    • Evidence for the involvement of the Wnt 2 gene in human colorectal cancer
    • B.Z. Vider, A. Zimber, E. Chastre, S. Prevot, C. Gespach, and D. Estlein Evidence for the involvement of the Wnt 2 gene in human colorectal cancer Oncogene 12 1996 153 158
    • (1996) Oncogene , vol.12 , pp. 153-158
    • Vider, B.Z.1    Zimber, A.2    Chastre, E.3    Prevot, S.4    Gespach, C.5    Estlein, D.6
  • 42
    • 0036342469 scopus 로고    scopus 로고
    • Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma
    • R.F. Holcombe, J.L. Marsh, M.L. Waterman, F. Lin, T. Milovanovic, and T. Truong Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma Mol. Pathol. 55 2002 220 226
    • (2002) Mol. Pathol. , vol.55 , pp. 220-226
    • Holcombe, R.F.1    Marsh, J.L.2    Waterman, M.L.3    Lin, F.4    Milovanovic, T.5    Truong, T.6
  • 43
    • 0035650631 scopus 로고    scopus 로고
    • Differential regulation of WNT2 and WNT2B expression in human cancer
    • M. Katoh Differential regulation of WNT2 and WNT2B expression in human cancer Int. J. Mol. Med. 8 2001 657 660
    • (2001) Int. J. Mol. Med. , vol.8 , pp. 657-660
    • Katoh, M.1
  • 44
    • 0141884398 scopus 로고    scopus 로고
    • Wnt ligand expression in malignant melanoma: Pilot study indicating correlation with histopathological features
    • K. Pham, T. Milovanovic, R.J. Barr, T. Truong, and R.F. Holcombe Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features Mol. Pathol. 56 2003 280 285
    • (2003) Mol. Pathol. , vol.56 , pp. 280-285
    • Pham, K.1    Milovanovic, T.2    Barr, R.J.3    Truong, T.4    Holcombe, R.F.5
  • 45
    • 4344570800 scopus 로고    scopus 로고
    • Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells
    • L. You, B. He, Z. Xu, K. Uematsu, J. Mazieres, and I. Mikami Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells Oncogene 23 2004 6170 6174
    • (2004) Oncogene , vol.23 , pp. 6170-6174
    • You, L.1    He, B.2    Xu, Z.3    Uematsu, K.4    Mazieres, J.5    Mikami, I.6
  • 49
    • 0031128225 scopus 로고    scopus 로고
    • WNTs modulate cell fate and behavior during vertebrate development
    • R.T. Moon, J.D. Brown, and M. Torres WNTs modulate cell fate and behavior during vertebrate development Trends Genet. 13 1997 157 162
    • (1997) Trends Genet. , vol.13 , pp. 157-162
    • Moon, R.T.1    Brown, J.D.2    Torres, M.3
  • 50
    • 0036583231 scopus 로고    scopus 로고
    • Frequent up-regulation of WNT5A mRNA in primary gastric cancer
    • T. Saitoh, T. Mine, and M. Katoh Frequent up-regulation of WNT5A mRNA in primary gastric cancer Int. J. Mol. Med. 9 2002 515 519
    • (2002) Int. J. Mol. Med. , vol.9 , pp. 515-519
    • Saitoh, T.1    Mine, T.2    Katoh, M.3
  • 51
    • 0345356929 scopus 로고    scopus 로고
    • Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
    • H. Liang, Q. Chen, A.H. Coles, S.J. Anderson, G. Pihan, and A. Bradley Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue Cancer Cell 4 2003 349 360
    • (2003) Cancer Cell , vol.4 , pp. 349-360
    • Liang, H.1    Chen, Q.2    Coles, A.H.3    Anderson, S.J.4    Pihan, G.5    Bradley, A.6
  • 52
    • 0345304776 scopus 로고    scopus 로고
    • Biological properties and gene expression associated with metastatic potential of human osteosarcoma
    • T. Nakano, M. Tani, Y. Ishibashi, K. Kimura, Y.B. Park, and N. Imaizumi Biological properties and gene expression associated with metastatic potential of human osteosarcoma Clin. Exp. Metastasis 20 2003 665 674
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 665-674
    • Nakano, T.1    Tani, M.2    Ishibashi, Y.3    Kimura, K.4    Park, Y.B.5    Imaizumi, N.6
  • 53
    • 0031457978 scopus 로고    scopus 로고
    • The mouse fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
    • L. Zeng, F. Fagotto, T. Zhang, W. Hsu, T.J. Vasicek, and W.L. Perry 3rd The mouse fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation Cell 90 1997 181 192
    • (1997) Cell , vol.90 , pp. 181-192
    • Zeng, L.1    Fagotto, F.2    Zhang, T.3    Hsu, W.4    Vasicek, T.J.5    Perry III, W.L.6
  • 54
    • 0031171361 scopus 로고    scopus 로고
    • PDZ domains: Targeting signalling molecules to sub-membranous sites
    • C.P. Ponting, C. Phillips, K.E. Davies, and D.J. Blake PDZ domains: targeting signalling molecules to sub-membranous sites Bioessays 19 1997 469 479
    • (1997) Bioessays , vol.19 , pp. 469-479
    • Ponting, C.P.1    Phillips, C.2    Davies, K.E.3    Blake, D.J.4
  • 55
    • 0030200001 scopus 로고    scopus 로고
    • Pleckstrin's repeat performance: A novel domain in G-protein signaling?
    • C.P. Ponting, and P. Bork Pleckstrin's repeat performance: a novel domain in G-protein signaling? Trends Biochem. Sci. 21 1996 245 246
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 245-246
    • Ponting, C.P.1    Bork, P.2
  • 56
    • 0242551656 scopus 로고    scopus 로고
    • Activation of the Wnt pathway in non small cell lung cancer: Evidence of dishevelled overexpression
    • K. Uematsu, B. He, L. You, Z. Xu, F. McCormick, and D.M. Jablons Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression Oncogene 22 2003 7218 7221
    • (2003) Oncogene , vol.22 , pp. 7218-7221
    • Uematsu, K.1    He, B.2    You, L.3    Xu, Z.4    McCormick, F.5    Jablons, D.M.6
  • 57
    • 0043092191 scopus 로고    scopus 로고
    • Wnt pathway activation in mesothelioma: Evidence of dishevelled overexpression and transcriptional activity of beta-catenin
    • K. Uematsu, S. Kanazawa, L. You, B. He, Z. Xu, and K. Li Wnt pathway activation in mesothelioma: evidence of dishevelled overexpression and transcriptional activity of beta-catenin Cancer Res. 63 2003 4547 4551
    • (2003) Cancer Res. , vol.63 , pp. 4547-4551
    • Uematsu, K.1    Kanazawa, S.2    You, L.3    He, B.4    Xu, Z.5    Li, K.6
  • 58
    • 0037229938 scopus 로고    scopus 로고
    • Runnin' with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
    • K.A. Wharton Jr. Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction Dev. Biol. 253 2003 1 17
    • (2003) Dev. Biol. , vol.253 , pp. 1-17
    • Wharton Jr., K.A.1
  • 59
    • 0036469157 scopus 로고    scopus 로고
    • Increased expression of beta-catenin predicts better prognosis in nonsmall cell lung carcinomas
    • F. Hommura, K. Furuuchi, K. Yamazaki, S. Ogura, I. Kinoshita, and M. Shimizu Increased expression of beta-catenin predicts better prognosis in nonsmall cell lung carcinomas Cancer 94 2002 752 758
    • (2002) Cancer , vol.94 , pp. 752-758
    • Hommura, F.1    Furuuchi, K.2    Yamazaki, K.3    Ogura, S.4    Kinoshita, I.5    Shimizu, M.6
  • 60
    • 0032431279 scopus 로고    scopus 로고
    • The expression of beta-catenin in non-small-cell lung cancer: A clinicopathological study
    • J.M. Retera, M.P. Leers, M.A. Sulzer, and P.H. Theunissen The expression of beta-catenin in non-small-cell lung cancer: a clinicopathological study J. Clin. Pathol. 51 1998 891 894
    • (1998) J. Clin. Pathol. , vol.51 , pp. 891-894
    • Retera, J.M.1    Leers, M.P.2    Sulzer, M.A.3    Theunissen, P.H.4
  • 61
    • 0034489809 scopus 로고    scopus 로고
    • Expression of E-cadherin and beta-catenin in human non-small cell lung cancer and the clinical significance
    • S. Kase, K. Sugio, K. Yamazaki, T. Okamoto, T. Yano, and K. Sugimachi Expression of E-cadherin and beta-catenin in human non-small cell lung cancer and the clinical significance Clin. Cancer Res. 6 2000 4789 4796
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4789-4796
    • Kase, S.1    Sugio, K.2    Yamazaki, K.3    Okamoto, T.4    Yano, T.5    Sugimachi, K.6
  • 62
  • 63
    • 0035146996 scopus 로고    scopus 로고
    • Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma
    • N. Sunaga, T. Kohno, F.T. Kolligs, E.R. Fearon, R. Saito, and J. Yokota Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma Genes Chromosomes Cancer 30 2001 316 321
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 316-321
    • Sunaga, N.1    Kohno, T.2    Kolligs, F.T.3    Fearon, E.R.4    Saito, R.5    Yokota, J.6
  • 64
    • 17944377840 scopus 로고    scopus 로고
    • Genetic alteration of the beta-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion
    • K. Shigemitsu, Y. Sekido, N. Usami, S. Mori, M. Sato, and Y. Horio Genetic alteration of the beta-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion Oncogene 20 2001 4249 4257
    • (2001) Oncogene , vol.20 , pp. 4249-4257
    • Shigemitsu, K.1    Sekido, Y.2    Usami, N.3    Mori, S.4    Sato, M.5    Horio, Y.6
  • 65
    • 0035816261 scopus 로고    scopus 로고
    • Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas
    • M. Ueda, R.M. Gemmill, J. West, R. Winn, M. Sugita, and N. Tanaka Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas Br. J. Cancer 85 2001 64 68
    • (2001) Br. J. Cancer , vol.85 , pp. 64-68
    • Ueda, M.1    Gemmill, R.M.2    West, J.3    Winn, R.4    Sugita, M.5    Tanaka, N.6
  • 66
    • 18444380534 scopus 로고    scopus 로고
    • Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: Up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules
    • Y. Nakatani, K. Masudo, Y. Miyagi, Y. Inayama, N. Kawano, and Y. Tanaka Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules Mod. Pathol. 15 2002 617 624
    • (2002) Mod. Pathol. , vol.15 , pp. 617-624
    • Nakatani, Y.1    Masudo, K.2    Miyagi, Y.3    Inayama, Y.4    Kawano, N.5    Tanaka, Y.6
  • 67
    • 0029909652 scopus 로고    scopus 로고
    • Loss of heterozygosity at 5q21 in non-small cell lung cancer: A frequent event but without evidence of apc mutation
    • C.A. Cooper, V.J. Bubb, N. Smithson, R.L. Carter, S. Gledhill, and D. Lamb Loss of heterozygosity at 5q21 in non-small cell lung cancer: a frequent event but without evidence of apc mutation J. Pathol. 180 1996 33 37
    • (1996) J. Pathol. , vol.180 , pp. 33-37
    • Cooper, C.A.1    Bubb, V.J.2    Smithson, N.3    Carter, R.L.4    Gledhill, S.5    Lamb, D.6
  • 68
    • 0026470030 scopus 로고
    • Frequent somatic mutations of the APC gene in human pancreatic cancer
    • A. Horii, S. Nakatsuru, Y. Miyoshi, S. Ichii, H. Nagase, and H. Ando Frequent somatic mutations of the APC gene in human pancreatic cancer Cancer Res. 52 1992 6696 6698
    • (1992) Cancer Res. , vol.52 , pp. 6696-6698
    • Horii, A.1    Nakatsuru, S.2    Miyoshi, Y.3    Ichii, S.4    Nagase, H.5    Ando, H.6
  • 71
    • 0035966322 scopus 로고    scopus 로고
    • Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
    • R. Habas, Y. Kato, and X. He Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1 Cell 107 2001 843 854
    • (2001) Cell , vol.107 , pp. 843-854
    • Habas, R.1    Kato, Y.2    He, X.3
  • 72
    • 0037090909 scopus 로고    scopus 로고
    • Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway
    • S.C. Choi, and J.K. Han Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway Dev. Biol. 244 2002 342 357
    • (2002) Dev. Biol. , vol.244 , pp. 342-357
    • Choi, S.C.1    Han, J.K.2
  • 73
    • 0037447932 scopus 로고    scopus 로고
    • Activation of Gbetagamma signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation
    • A. Penzo-Mendez, M. Umbhauer, A. Djiane, J.C. Boucaut, and J.F. Riou Activation of Gbetagamma signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation Dev. Biol. 257 2003 302 314
    • (2003) Dev. Biol. , vol.257 , pp. 302-314
    • Penzo-Mendez, A.1    Umbhauer, M.2    Djiane, A.3    Boucaut, J.C.4    Riou, J.F.5
  • 75
    • 0038175548 scopus 로고    scopus 로고
    • Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation
    • L.L. Soon, T.A. Yie, A. Shvarts, A.J. Levine, F. Su, and K.M. Tchou-Wong Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation J. Biol. Chem. 278 2003 11465 11470
    • (2003) J. Biol. Chem. , vol.278 , pp. 11465-11470
    • Soon, L.L.1    Yie, T.A.2    Shvarts, A.3    Levine, A.J.4    Su, F.5    Tchou-Wong, K.M.6
  • 76
    • 0035878110 scopus 로고    scopus 로고
    • Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1
    • W. Tao, D. Pennica, L. Xu, R.F. Kalejta, and A.J. Levine Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1 Genes Dev. 15 2001 1796 1807
    • (2001) Genes Dev. , vol.15 , pp. 1796-1807
    • Tao, W.1    Pennica, D.2    Xu, L.3    Kalejta, R.F.4    Levine, A.J.5
  • 77
    • 0037439138 scopus 로고    scopus 로고
    • Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
    • R. Habas, I.B. Dawid, and X. He Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation Genes Dev. 17 2003 295 309
    • (2003) Genes Dev. , vol.17 , pp. 295-309
    • Habas, R.1    Dawid, I.B.2    He, X.3
  • 78
    • 0034613286 scopus 로고    scopus 로고
    • RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription
    • C. Allal, G. Favre, B. Couderc, S. Salicio, S. Sixou, and A.D. Hamilton RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription J. Biol. Chem. 275 2000 31001 31008
    • (2000) J. Biol. Chem. , vol.275 , pp. 31001-31008
    • Allal, C.1    Favre, G.2    Couderc, B.3    Salicio, S.4    Sixou, S.5    Hamilton, A.D.6
  • 80
    • 1042278714 scopus 로고    scopus 로고
    • A definitive role of RhoC in metastasis of orthotopic lung cancer in mice
    • T. Ikoma, T. Takahashi, S. Nagano, Y.M. Li, Y. Ohno, and K. Ando A definitive role of RhoC in metastasis of orthotopic lung cancer in mice Clin. Cancer Res. 10 2004 1192 1200
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1192-1200
    • Ikoma, T.1    Takahashi, T.2    Nagano, S.3    Li, Y.M.4    Ohno, Y.5    Ando, K.6
  • 82
    • 0037158893 scopus 로고    scopus 로고
    • Differentially expressed genes associated with mouse lung tumor progression
    • R. Yao, Y. Wang, R.A. Lubet, and M. You Differentially expressed genes associated with mouse lung tumor progression Oncogene 21 2002 5814 5821
    • (2002) Oncogene , vol.21 , pp. 5814-5821
    • Yao, R.1    Wang, Y.2    Lubet, R.A.3    You, M.4
  • 83
    • 0141756144 scopus 로고    scopus 로고
    • Role of Rho-family proteins in cell adhesion and cancer
    • A. Malliri, and J.G. Collard Role of Rho-family proteins in cell adhesion and cancer Curr. Opin. Cell Biol. 15 2003 583 589
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 583-589
    • Malliri, A.1    Collard, J.G.2
  • 84
    • 0032504052 scopus 로고    scopus 로고
    • Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
    • M. Boutros, N. Paricio, D.I. Strutt, and M. Mlodzik Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling Cell 94 1998 109 118
    • (1998) Cell , vol.94 , pp. 109-118
    • Boutros, M.1    Paricio, N.2    Strutt, D.I.3    Mlodzik, M.4
  • 85
    • 0032695975 scopus 로고    scopus 로고
    • Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates
    • T. Moriguchi, K. Kawachi, S. Kamakura, N. Masuyama, H. Yamanaka, and K. Matsumoto Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates J. Biol. Chem. 274 1999 30957 30962
    • (1999) J. Biol. Chem. , vol.274 , pp. 30957-30962
    • Moriguchi, T.1    Kawachi, K.2    Kamakura, S.3    Masuyama, N.4    Yamanaka, H.5    Matsumoto, K.6
  • 86
    • 2442694379 scopus 로고    scopus 로고
    • Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells
    • L. You, B. He, K. Uematsu, Z. Xu, J. Mazieres, and A. Lee Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells Cancer Res. 64 2004 3474 3478
    • (2004) Cancer Res. , vol.64 , pp. 3474-3478
    • You, L.1    He, B.2    Uematsu, K.3    Xu, Z.4    Mazieres, J.5    Lee, A.6
  • 87
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Y. Kawano, and R. Kypta Secreted antagonists of the Wnt signalling pathway J. Cell Sci. 116 2003 2627 2634
    • (2003) J. Cell Sci. , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 88
    • 0036429396 scopus 로고    scopus 로고
    • Human secreted frizzled-related protein is down-regulated and induces apoptosis in human cervical cancer
    • J. Ko, K.S. Ryu, Y.H. Lee, D.S. Na, Y.S. Kim, and Y.M. Oh Human secreted frizzled-related protein is down-regulated and induces apoptosis in human cervical cancer Exp. Cell Res. 280 2002 280 287
    • (2002) Exp. Cell Res. , vol.280 , pp. 280-287
    • Ko, J.1    Ryu, K.S.2    Lee, Y.H.3    Na, D.S.4    Kim, Y.S.5    Oh, Y.M.6
  • 89
    • 0035855667 scopus 로고    scopus 로고
    • WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type
    • F. Ugolini, E. Charafe-Jauffret, V.J. Bardou, J. Geneix, J. Adelaide, and F. Labat-Moleur WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type Oncogene 20 2001 5810 5817
    • (2001) Oncogene , vol.20 , pp. 5810-5817
    • Ugolini, F.1    Charafe-Jauffret, E.2    Bardou, V.J.3    Geneix, J.4    Adelaide, J.5    Labat-Moleur, F.6
  • 90
    • 0035861791 scopus 로고    scopus 로고
    • Alterations of frizzled (FzE3) and secreted frizzled related protein (hsFRP) expression in gastric cancer
    • K.F. To, M.W. Chan, W.K. Leung, J. Yu, J.H. Tong, and T.L. Lee Alterations of frizzled (FzE3) and secreted frizzled related protein (hsFRP) expression in gastric cancer Life Sci. 70 2001 483 489
    • (2001) Life Sci. , vol.70 , pp. 483-489
    • To, K.F.1    Chan, M.W.2    Leung, W.K.3    Yu, J.4    Tong, J.H.5    Lee, T.L.6
  • 91
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • H. Suzuki, E. Gabrielson, W. Chen, R. Anbazhagan, M. van Engeland, and M.P. Weijenberg A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer Nat. Genet. 31 2002 141 149
    • (2002) Nat. Genet. , vol.31 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chen, W.3    Anbazhagan, R.4    Van Engeland, M.5    Weijenberg, M.P.6
  • 95
    • 0141995804 scopus 로고    scopus 로고
    • WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer
    • C. Wissmann, P.J. Wild, S. Kaiser, S. Roepcke, R. Stoehr, and M. Woenckhaus WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer J. Pathol. 201 2003 204 212
    • (2003) J. Pathol. , vol.201 , pp. 204-212
    • Wissmann, C.1    Wild, P.J.2    Kaiser, S.3    Roepcke, S.4    Stoehr, R.5    Woenckhaus, M.6
  • 96
    • 3142679453 scopus 로고    scopus 로고
    • Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer
    • J. Mazieres, B. He, L. You, Z. Xu, A.Y. Lee, and I. Mikami Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer Cancer Res. 64 2004 4717 4720
    • (2004) Cancer Res. , vol.64 , pp. 4717-4720
    • Mazieres, J.1    He, B.2    You, L.3    Xu, Z.4    Lee, A.Y.5    Mikami, I.6
  • 97
    • 4444343396 scopus 로고    scopus 로고
    • Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma
    • A.Y. Lee, B. He, L. You, S. Dadfarmay, Z. Xu, and J. Mazieres Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma Oncogene 2004
    • (2004) Oncogene
    • Lee, A.Y.1    He, B.2    You, L.3    Dadfarmay, S.4    Xu, Z.5    Mazieres, J.6
  • 98
    • 0033516577 scopus 로고    scopus 로고
    • Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling
    • P. Fedi, A. Bafico, A. Nieto Soria, W.H. Burgess, T. Miki, and D.P. Bottaro Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling J. Biol. Chem. 274 1999 19465 19472
    • (1999) J. Biol. Chem. , vol.274 , pp. 19465-19472
    • Fedi, P.1    Bafico, A.2    Nieto Soria, A.3    Burgess, W.H.4    Miki, T.5    Bottaro, D.P.6
  • 99
    • 0034607050 scopus 로고    scopus 로고
    • A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines
    • T. Tsuji, M. Miyazaki, M. Sakaguchi, Y. Inoue, and M. Namba A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines Biochem. Biophys. Res. Commun. 268 2000 20 24
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 20-24
    • Tsuji, T.1    Miyazaki, M.2    Sakaguchi, M.3    Inoue, Y.4    Namba, M.5
  • 101
    • 0035940982 scopus 로고    scopus 로고
    • Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas
    • T. Tsuji, I. Nozaki, M. Miyazaki, M. Sakaguchi, H. Pu, and Y. Hamazaki Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas Biochem. Biophys. Res. Commun. 289 2001 257 263
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 257-263
    • Tsuji, T.1    Nozaki, I.2    Miyazaki, M.3    Sakaguchi, M.4    Pu, H.5    Hamazaki, Y.6
  • 102
    • 0037045429 scopus 로고    scopus 로고
    • Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells
    • K. Kobayashi, M. Ouchida, T. Tsuji, H. Hanafusa, M. Miyazaki, and M. Namba Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells Gene 282 2002 151 158
    • (2002) Gene , vol.282 , pp. 151-158
    • Kobayashi, K.1    Ouchida, M.2    Tsuji, T.3    Hanafusa, H.4    Miyazaki, M.5    Namba, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.