Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas

Biochemical and Biophysical Research Communications

Volumn 289, Issue 1, 2001, Pages 257-263

  Tsuji, Toshiya ^a   Nozaki, Isao ^a   Miyazaki, Masahiro ^a   Sakaguchi, Masakiyo ^a   Pu, Hong ^a   Hamazaki, Yusuke ^a   Iijima, Osamu ^b   Namba, Masayoshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b HISAMITSU PHARMACEUTICAL CO INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MESSENGER RNA; PROTEIN DKK 3; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CHROMOSOME 11P; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE LOCUS; GROWTH INHIBITION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0035940982     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5972     Document Type: Article

References (25)

1. A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines
2. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
3. Functional and structural diversity of the human Dickkopf gene family
4. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
5. Transformation by Wnt family proteins correlates with regulation of beta-catenin
6. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
7. Stabilization of beta-catenin by genetic defects in melanoma cell lines
8. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
9. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
10. Apoptosis and APC in colorectal tumorigenesis
11. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
12. Allelotype analysis of oesophageal adenocarcinoma: Loss of heterozygosity occurs at multiple sites
13. Allelic loss and replication errors at microsatellite loci on chromosome 11p in head and neck squamous carcinoma: Association with aggressive biological features
14. Allelic loss on the short arm of chromosome 11 in non-small-cell lung cancer
15. Loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in Taiwan
16. Loss of Heterozygosity for chromosome 11 in adenocarcinoma of the stomach
17. Refinement of regional loss of heterozygosity for chromosome 11p15.5 in human breast tumors
18. Deletion of chromosome 11p15, p12, q22, q23-24 loci in human prostrate cancer
19. Chromosomal localization of two putative 11p oncosuppressor genes involved in human ovarian tumours
20. Localization of a tumor suppressor gene in 11p15.5 using the G401 Wilms' tumor assay
21. Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11
22. Multiple loci on human chromosome 11 control tumorigenicity of BK virus transformed cells
23. Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: An introduction
24. Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15
25. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling