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Volumn 10, Issue 3, 2004, Pages 1192-1200

A Definitive Role of RhoC in Metastasis of Orthotopic Lung Cancer in Mice

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GUANINE NUCLEOTIDE BINDING PROTEIN; MATRIX METALLOPROTEINASE; PROTEIN DNRHO; PROTEIN RHOC; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 1042278714     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0275     Document Type: Article
Times cited : (98)

References (42)
  • 1
    • 0037216616 scopus 로고    scopus 로고
    • Classification, staging and prognosis of lung cancer
    • Beadsmoore, C. J., and Screaton, N. J. Classification, staging and prognosis of lung cancer. Eur. J. Radiol., 45: 8-17, 2003.
    • (2003) Eur. J. Radiol. , vol.45 , pp. 8-17
    • Beadsmoore, C.J.1    Screaton, N.J.2
  • 2
    • 0037246734 scopus 로고    scopus 로고
    • Follow-up and surveillance of the lung cancer patient following curative-intent therapy
    • Colice, G. L., Rubins, J., and Unger, M. Follow-up and surveillance of the lung cancer patient following curative-intent therapy. Chest, 123: 272S-283S, 2003.
    • (2003) Chest , vol.123
    • Colice, G.L.1    Rubins, J.2    Unger, M.3
  • 4
    • 0033215250 scopus 로고    scopus 로고
    • Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: A 7-year assessment of a randomized controlled trial
    • Rosell, R., Gomez-Codina, J., Camps, C., Javier Sanchez, J., Maestre, J., Padilla, J., Canto, A., Abad, A., and Roig, J. Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: a 7-year assessment of a randomized controlled trial. Lung Cancer, 26: 7-14, 1999.
    • (1999) Lung Cancer , vol.26 , pp. 7-14
    • Rosell, R.1    Gomez-Codina, J.2    Camps, C.3    Javier Sanchez, J.4    Maestre, J.5    Padilla, J.6    Canto, A.7    Abad, A.8    Roig, J.9
  • 5
    • 0028997226 scopus 로고
    • Long-term survival in small-cell lung cancer: Posttreatment characteristics in patients surviving 5 to 18+ years - An analysis of 1,714 consecutive patients
    • Lassen, U., Osterlind, K., Hansen, M., Dombernowsky, P., Bergman, B., and Hansen, H. H. Long-term survival in small-cell lung cancer: posttreatment characteristics in patients surviving 5 to 18+ years - an analysis of 1,714 consecutive patients. J. Clin. Oncol., 13: 1215-1220, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1215-1220
    • Lassen, U.1    Osterlind, K.2    Hansen, M.3    Dombernowsky, P.4    Bergman, B.5    Hansen, H.H.6
  • 6
    • 0036263780 scopus 로고    scopus 로고
    • Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model
    • Fukunaga, M., Takamori, S., Hayashi, A., Shirouzu, K., and Kosai, K. Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model. Ann. Thorac. Surg., 73: 1740-1746, 2002.
    • (2002) Ann. Thorac. Surg. , vol.73 , pp. 1740-1746
    • Fukunaga, M.1    Takamori, S.2    Hayashi, A.3    Shirouzu, K.4    Kosai, K.5
  • 7
    • 0030701975 scopus 로고    scopus 로고
    • Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer
    • Kwong, Y. L., Chen, S. H., Kosai, K., Finegold, M., and Woo, S. L. Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer. Chest, 112: 1332-1337, 1997.
    • (1997) Chest , vol.112 , pp. 1332-1337
    • Kwong, Y.L.1    Chen, S.H.2    Kosai, K.3    Finegold, M.4    Woo, S.L.5
  • 8
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta, L. A., Steeg, P. S., and Stetler-Stevenson, W. G. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell, 64: 327-336, 1991.
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 9
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark, E. A., Golub, T. R., Lander, E. S., and Hynes, R. O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature (Lond.), 406: 532-535, 2000.
    • (2000) Nature (Lond.) , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 11
    • 0031042493 scopus 로고    scopus 로고
    • Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton
    • Tapon, N., and Hall, A. Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol., 9: 86-92, 1997.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 86-92
    • Tapon, N.1    Hall, A.2
  • 13
    • 0036599583 scopus 로고    scopus 로고
    • Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor
    • van Golen, K. L., Bao, L., DiVito, M. M., Wu, Z., Prendergast, G. C., and Merajver, S. D. Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor. Mol. Cancer Ther., 1: 575-583, 2002.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 575-583
    • Van Golen, K.L.1    Bao, L.2    DiVito, M.M.3    Wu, Z.4    Prendergast, G.C.5    Merajver, S.D.6
  • 14
    • 0036168355 scopus 로고    scopus 로고
    • Characterization of RhoC expression in benign and malignant breast disease: A potential new marker for small breast carcinomas with metastatic ability
    • Kleer, C. G., van Golen, K. L., Zhang, Y., Wu, Z. F., Rubin, M. A., and Merajver, S. D. Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability. Am. J. Pathol., 160: 579-584, 2002.
    • (2002) Am. J. Pathol. , vol.160 , pp. 579-584
    • Kleer, C.G.1    Van Golen, K.L.2    Zhang, Y.3    Wu, Z.F.4    Rubin, M.A.5    Merajver, S.D.6
  • 15
    • 0038679226 scopus 로고    scopus 로고
    • Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
    • Horiuchi, A., Imai, T., Wang, C., Ohira, S., Feng, Y., Nikaido, T., and Konishi, I. Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma. Lab. Investig., 83: 861-870, 2003.
    • (2003) Lab. Investig. , vol.83 , pp. 861-870
    • Horiuchi, A.1    Imai, T.2    Wang, C.3    Ohira, S.4    Feng, Y.5    Nikaido, T.6    Konishi, I.7
  • 18
    • 0030044503 scopus 로고    scopus 로고
    • Cellular activation of mesangial gelatinase A by cytochalasin D is accompanied by enhanced mRNA expression of both gelatinase A and its membrane-associated gelatinase A activator (MT-MMP)
    • Ailenberg, M., and Silverman, M. Cellular activation of mesangial gelatinase A by cytochalasin D is accompanied by enhanced mRNA expression of both gelatinase A and its membrane-associated gelatinase A activator (MT-MMP). Biochem. J., 313: 879-884, 1996.
    • (1996) Biochem. J. , vol.313 , pp. 879-884
    • Ailenberg, M.1    Silverman, M.2
  • 21
    • 0032503632 scopus 로고    scopus 로고
    • Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy
    • Kosai, K. I., Finegold, M. J., Thi-Huynh, B. T., Tewson, M., Ou, C. N., Bowles, N., Woo, S. L., Schwall, R. H., and Darlington, G. J. Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy. Hum. Gene Ther., 9: 1293-1301, 1998.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1293-1301
    • Kosai, K.I.1    Finegold, M.J.2    Thi-Huynh, B.T.3    Tewson, M.4    Ou, C.N.5    Bowles, N.6    Woo, S.L.7    Schwall, R.H.8    Darlington, G.J.9
  • 22
    • 0033025433 scopus 로고    scopus 로고
    • Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice
    • Doki, Y., Murakami, K., Yamaura, T., Sugiyama, S., Misaki, T., and Saiki, I. Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice. Br. J. Cancer, 79: 1121-1126, 1999.
    • (1999) Br. J. Cancer , vol.79 , pp. 1121-1126
    • Doki, Y.1    Murakami, K.2    Yamaura, T.3    Sugiyama, S.4    Misaki, T.5    Saiki, I.6
  • 23
    • 0030886204 scopus 로고    scopus 로고
    • Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
    • Liu, X., Sun, Y., Constantinescu, S. N., Karam, E., Weinberg, R. A., and Lodish, H. F. Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. USA, 94: 10669-10674, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10669-10674
    • Liu, X.1    Sun, Y.2    Constantinescu, S.N.3    Karam, E.4    Weinberg, R.A.5    Lodish, H.F.6
  • 26
    • 0024296427 scopus 로고
    • Coding sequence of human rho cDNAs clone 6 and clone 9
    • Chardin, P., Madaule, P., and Tavitian, A. Coding sequence of human rho cDNAs clone 6 and clone 9. Nucleic Acids Res., 16: 2717, 1988.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 2717
    • Chardin, P.1    Madaule, P.2    Tavitian, A.3
  • 28
    • 20244378633 scopus 로고    scopus 로고
    • RhoA is associated with invasion and lymph node metastasis in upper urinary tract cancer
    • Kamai, T., Kawakami, S., Koga, F., Arai, G., Takagi, K., Arai, K., Tsujii, T., and Yoshida, K. I. RhoA is associated with invasion and lymph node metastasis in upper urinary tract cancer. BJU Int., 91: 234-238, 2003.
    • (2003) BJU Int. , vol.91 , pp. 234-238
    • Kamai, T.1    Kawakami, S.2    Koga, F.3    Arai, G.4    Takagi, K.5    Arai, K.6    Tsujii, T.7    Yoshida, K.I.8
  • 29
    • 0032939619 scopus 로고    scopus 로고
    • Rho GTPases are over-expressed in human tumors
    • Fritz, G., Just, I., and Kaina, B. Rho GTPases are over-expressed in human tumors. Int. J. Cancer, 81: 682-687, 1999.
    • (1999) Int. J. Cancer , vol.81 , pp. 682-687
    • Fritz, G.1    Just, I.2    Kaina, B.3
  • 30
    • 0036280716 scopus 로고    scopus 로고
    • Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer
    • van Golen, K. L., Bao, L. W., Pan, Q., Miller, F. R., Wu, Z. F., and Merajver, S. D. Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer. Clin. Exp. Metastasis, 19: 301-311, 2002.
    • (2002) Clin. Exp. Metastasis , vol.19 , pp. 301-311
    • Van Golen, K.L.1    Bao, L.W.2    Pan, Q.3    Miller, F.R.4    Wu, Z.F.5    Merajver, S.D.6
  • 31
    • 0037817325 scopus 로고    scopus 로고
    • Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer
    • Kamai, T., Tsujii, T., Arai, K., Takagi, K., Asami, H., Ito, Y., and Oshima, H. Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer. Clin. Cancer Res., 9: 2632-2641, 2003.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2632-2641
    • Kamai, T.1    Tsujii, T.2    Arai, K.3    Takagi, K.4    Asami, H.5    Ito, Y.6    Oshima, H.7
  • 32
    • 0037048326 scopus 로고    scopus 로고
    • Rho GTPases in human breast tumours: Expression and mutation analyses and correlation with clinical parameters
    • Fritz, G., Bráchetti, C., Bahlmann, F., Schmidt, M., and Kaina, B. Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters. Br. J. Cancer, 87: 635-644, 2002.
    • (2002) Br. J. Cancer , vol.87 , pp. 635-644
    • Fritz, G.1    Bráchetti, C.2    Bahlmann, F.3    Schmidt, M.4    Kaina, B.5
  • 33
    • 0030904698 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells
    • Tokman, M. G., Porter, R. A., and Williams, C. L. Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells. Cancer Res., 57: 1785-1793, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1785-1793
    • Tokman, M.G.1    Porter, R.A.2    Williams, C.L.3
  • 34
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
    • Khosravi-Far, R., Solski, P., Clark, G., Kinch, M., and Der, C. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol. Cell. Biol., 15: 6443-6453, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.2    Clark, G.3    Kinch, M.4    Der, C.5
  • 35
    • 0037426578 scopus 로고    scopus 로고
    • Membrane-type 1 matrix metalloproteinase: A key enzyme for tumor invasion
    • Seiki, M. Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion. Cancer Lett., 194: 1-11, 2003.
    • (2003) Cancer Lett. , vol.194 , pp. 1-11
    • Seiki, M.1
  • 36
    • 0037209271 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in lung cancer
    • Lim, M., and Jablons, D. M. Matrix metalloproteinase expression in lung cancer. Methods Mol. Med., 74: 349-356, 2003.
    • (2003) Methods Mol. Med. , vol.74 , pp. 349-356
    • Lim, M.1    Jablons, D.M.2
  • 37
    • 0028838487 scopus 로고
    • Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis
    • Tokuraku, M., Sato, H., Murakami, S., Okada, Y., Watanabe, Y., and Seiki, M. Activation of the precursor of gelatinase A/72 kDa type IV collagenase/ MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int. J. Cancer, 64: 355-359, 1995.
    • (1995) Int. J. Cancer , vol.64 , pp. 355-359
    • Tokuraku, M.1    Sato, H.2    Murakami, S.3    Okada, Y.4    Watanabe, Y.5    Seiki, M.6
  • 38
    • 0035844299 scopus 로고    scopus 로고
    • Rac1 mediates type I collagen-dependent MMP-2 activation: Role in cell invasion across collagen barrier
    • Zhuge, Y., and Xu, J. Rac1 mediates type I collagen-dependent MMP-2 activation: role in cell invasion across collagen barrier. J. Biol. Chem., 276: 16248-16256, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16248-16256
    • Zhuge, Y.1    Xu, J.2
  • 39
    • 0035834754 scopus 로고    scopus 로고
    • Rac affects invasion of human renal cell carcinomas by upregulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression
    • Engers, R., Springer, E., Michiels, F., Collard, J. G., and Gabbert, H. E. Rac affects invasion of human renal cell carcinomas by upregulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression. J. Biol. Chem., 276: 41889-41897, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41889-41897
    • Engers, R.1    Springer, E.2    Michiels, F.3    Collard, J.G.4    Gabbert, H.E.5
  • 40
    • 0035004670 scopus 로고    scopus 로고
    • Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells
    • Matsumoto, Y., Tanaka, K., Harimaya, K., Nakatani, F., Matsuda, S., and Iwamoto, Y. Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells. Jpn. J. Cancer Res., 92: 429-438, 2001.
    • (2001) Jpn. J. Cancer Res. , vol.92 , pp. 429-438
    • Matsumoto, Y.1    Tanaka, K.2    Harimaya, K.3    Nakatani, F.4    Matsuda, S.5    Iwamoto, Y.6
  • 41
    • 0035801473 scopus 로고    scopus 로고
    • Homophilic complex formation of MTI-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion
    • Itoh, Y., Takamura, A., Ito, N., Maru, Y., Sato, H., Suenaga, N., Aoki, T., and Seiki, M. Homophilic complex formation of MTI-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J., 20: 4782-4793, 2001.
    • (2001) EMBO J. , vol.20 , pp. 4782-4793
    • Itoh, Y.1    Takamura, A.2    Ito, N.3    Maru, Y.4    Sato, H.5    Suenaga, N.6    Aoki, T.7    Seiki, M.8
  • 42
    • 0036683241 scopus 로고    scopus 로고
    • CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain
    • Mori, H., Tomari, T., Koshikawa, N., Kajita, M., Itoh, Y., Sato, H., Tojo, H., Yana, I., and Seiki, M. CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain. EMBO J., 21: 3949-3959, 2002.
    • (2002) EMBO J. , vol.21 , pp. 3949-3959
    • Mori, H.1    Tomari, T.2    Koshikawa, N.3    Kajita, M.4    Itoh, Y.5    Sato, H.6    Tojo, H.7    Yana, I.8    Seiki, M.9


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