Expression of E-cadherin and β-catenin in human non-small cell lung cancer and the clinical significance

Clinical Cancer Research

Volumn 6, Issue 12, 2000, Pages 4789-4796

  Kase, S ^a   Sugio, K ^a   Yamazaki, K ^a   Okamoto, T ^a   Yano, T ^a   Sugimachi, K ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SURVIVAL RATE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BETA CATENIN; BLOTTING, WESTERN; CADHERINS; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CYTOSKELETAL PROTEINS; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHENOTYPE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTEIN BINDING; TIME FACTORS; TRANS-ACTIVATORS;

EID: 0034489809     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Results of surgical treatment of stage I and II lung cancer
2. Prognostic factors in clinical stage I non-small cell lung cancer
3. Stage I non-small cell lung cancer. A multivariate analysis of treatment methods and patterns of recurrence
4. Prognostic significance of surgical-pathologic N1 disease in non-small cell carcinoma of the lung
5. Revisions in the international system for staging lung cancer
6. Cadherin cell adhesion receptors as a morphogenetic regulator
7. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
8. Plakoglobin: A protein common to different kinds of intercellular adhering junctions
9. A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin
10. Plakoglobin and β-catenin: Distinct but closely related
11. Induction of a secondary body axis in Xenopus by antibodies to β-catenin
12. Association of the APC gene product with β-catenin
13. Association of the APC tumor suppressor protein with catenins
14. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
15. Stabilization of β-catenin by genetic defects in melanoma cell lines
16. Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: Correlation with disease progression and dedifferentiation
17. E-cadherin expression in primary and metastatic thoracic neoplasms and in Barrett's oesophagus
18. E-cadherin and α-catenin expression in human esophageal cancer
19. Reduced expression of the cadherin-catenin complex in oesophageal adenocarcinoma correlates with poor prognosis
20. Expression of E-cadherin, α-catenin, β-catenin and plakoglobin in esophageal carcinomas and its prognostic significance: Immunohistochemical analysis of 96 lesions
21. Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: Relationship with patient survival
22. Altered expression of E-cadherin in gastric cancer tissues and carcinomatous fluid
23. Expression of immunoreactive E-cadherin adhesion molecules in human cancers
24. E-cadherin expression in primary and metastatic gastric cancer: Down-regulation correlates with cellular dedifferentiation and glandular disintegration
25. Expression of E-cadherin, α, β and γ-catenin in human colorectal cancer
26. Expression of E-cadherin, α-catenin, β-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: An immunohistochemical study
27. Expression of epithelial cadherin and α- and β-catenins in nontumoral livers and hepatocellular carcinomas
28. Pancreatic carcinoma: Correlation between E-cadherin and α-catenin expression status and liver metastasis
29. Expression of E-cadherin in primary and metastatic prostate cancer
30. Aberrant E-cadherin and α-catenin expression in prostate cancer: Correlation with patient survival
31. Decreased E-cadherin expression is associated with poor prognosis in patients with prostate cancer
32. Prognostic value of cadherin-associated molecules (α-, β-, and γ-catenins and p120cas) in bladder tumors
33. Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer
34. Differences of E-cadherin expression levels and patterns in primary and metastatic human lung cancer
35. Immunohistochemical evaluation of E-cadherin and epidermal growth factor receptor in non-small cell lung cancer
36. Influence of E-cadherin dysfunction upon local invasion and metastasis in non-small cell lung cancer
37. The expression of β-catenin in non-small-cell lung cancer: A clinicopathological study
38. The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas
39. Aberrant expression and phosphorylation of β-catenin in human colorectal cancer
40. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas
41. The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas
42. The H-cadherin (CDH13) gene is inactivated in human lung cancer
43. Embryonic axis induction by the armadillo repeat domain of β-catenin: Evidence for intracellular signaling
44. Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice
45. The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plakoglobin
46. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
47. Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/- colon carcinoma