Wnt7b regulates mesenchymal proliferation and vascular development in the lung

Development

Volumn 129, Issue 20, 2002, Pages 4831-4842

  Shu, Weiguo ^a   Jiang, Yue Qin ^a   Lu, Min Min ^a   Morrisey, Edward E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Lung; Mesenchyme; Proliferation; Vascular smooth muscle; Wnt7b

Indexed keywords

BETA GALACTOSIDASE; WNT PROTEIN;

ANGIOGENESIS; ARTICLE; BLOOD VESSEL RUPTURE; CELL INTERACTION; CELL PROLIFERATION; CODING; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; EXON; GENE MUTATION; GERM LINE; HYPOTHESIS; LUNG BLOOD VESSEL; LUNG DEVELOPMENT; LUNG HEMORRHAGE; LUNG HYPOPLASIA; MESENCHYME CELL; MOUSE; NONHUMAN; PERINATAL DEATH; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM; RESPIRATORY FAILURE; VASCULAR SMOOTH MUSCLE;

ACTINS; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL DIVISION; EPITHELIAL CELLS; FETAL DEATH; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC ENGINEERING; GLYCOPROTEINS; LUNG; MESODERM; MICE; MICE, MUTANT STRAINS; MUSCLE, SMOOTH, VASCULAR; PROTO-ONCOGENE PROTEINS; RESPIRATORY INSUFFICIENCY; WNT PROTEINS;

EID: 0036802645     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Baker, J. C., Beddington, R. S. and Harland, R. M. (1999). Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development. Genes Dev. 13, 3149-3159.
2. Ballard, P. L. (1996). Neonatal respiratory disease due to surfactant protein B deficiency. J. Perinatol. 16, S28-S34.
3. Bellusei, S., Henderson, R., Winnier, G., Oikawa, T. and Hogan, B. L. (1996). Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development 122, 1693-1702.
4. Bellusci, S., Furuta, Y., Rush, M. G., Henderson, R., Winnier, G. and Hogan, B. L. (1997). Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development 124, 53-63.
5. Bradley, R. S. and Brown, A. M. (1995). A soluble form of Wnt-1 protein with mitogenic activity on mammary epitheliat cells. Mol. Cell. Biol. 15, 4616-4622.
6. Cadigan, K. M. and Nusse, R. (1997). Wnt signaling: a common theme in animal development. Genes Dev. 11, 3286-3305.
7. Colvin, J. S., White, A. C., Pratt, S. J. and Ornitz, D. M. (2001). Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. Development 128, 2095-2106.
8. Edwards, P. A., Hiby, S. E., Papkoff, J. and Bradbury, J. M. (1992). Hyperplasia of mouse mammary epithelium induced by expression of the Wnt-1 (int-1) oncogene in reconstituted mammary gland. Oncogene 7, 2041-2051.
9. Ellis, T., Gambardella, L., Horcher, M., Tschanz, S., Capol, J., Bertram, P., Jochum, W., Barrandon, Y. and Busslinger, M. (2001). The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle. Genes Dev. 15, 2307-2319.
10. Evans, M. J., Cabral, L. J., Stephens, R. J. and Freeman, G. (1975). Transformation of alveolar type 2 cells to type 1 cells following exposure to NO2. Exp. Mol. Pathol. 22, 142-150.
11. Gavin, B. J., McMahon, J. A. and McMahon, A. P. (1990). Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 4, 2319-2332.
12. Guyer, B., Hoyert, D. L., Martin, J. A., Ventura, S. J., MacDorman, M. F. and Strobino, D. M. (1999). Annual summary of vital statistics-1998. Pediatrics 104, 1229-1246.
13. Hans, F. and Dimitrov, S. (2001). Histone H3 phosphorylation and cell division. Oncogene 20, 3021-3027.
14. Hogan, B. L. and Yingling, J. M. (1998). Epithelial/mesenchymal interactions and branching morphogenesis of the lung. Curr Opin. Genet. Dev. 8, 481-486.
15. Hollyday, M., McMahon, J. A. and McMahon, A. P. (1995). Wnt expression patterns in chick embryo nervous system. Mech. Dev. 52, 9-25.
16. Hoppler, S., Brown, J. D. and Moon, R. T. (1996). Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes Dev. 10, 2805-2817.
17. Kim, S., Ip, H. S., Lu, M. M., Clendenin, C. and Parmacek, M. S. (1997). A serum response factor-dependent transcriptional regulatory program identifies distinct smooth muscle cell sublineages. Mol. Cell. Biol. 17, 2266-2278.
18. Kuo, C. T., Morrisey, E. E., Anandappa, R., Sigrist, K., Lu, M. M., Parmacek, M. S., Soudais, C. and Leiden, J. M. (1997). GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11, 1048-1060.
19. Lako, M., Strachan, T., Bullen, P., Wilson, D. I, Robson, S. C. and Lindsay, S. (1998). Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11ql3.5 and has possible roles in the development of skeleton, kidney and lung. Gene 219, 101-110.
20. Lee, M. D., King, L. S., Nielsen, S. and Agre, P. (1997). Genomic organization and developmental expression of aquaporin-5 in lung. Chest 111, 111S-113S.
21. Li, L., Liu, Z., Mercer, B., Overbeek, P. and Olson, E. N. (1997). Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cells. Dev. Biol. 187, 311-321.
22. Lickert, H., Domon, C., Huls, G., Wehrle, C., Dulue, L, Clevers, H., Meyer, B. I., Freund, J. N. and Kemler, R. (2000). Wnt(beta)-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine. Development 127, 3805-3813.
23. Lin, Y., Liu, A., Zhang, S., Ruusunen, T., Kreidberg, J. A., Peltoketo, H., Drummond, I. and Vainio, S. (2001). Induction of ureter branching as a response to Wnt-2b signaling during early kidney organogenesis. Dev. Dyn. 222, 26-39.
24. Lippincott-Schwartz, J., Bonifacino, J. S., Yuan, L. C. and Klausner, R. D. (1988). Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell 54, 209-220.
25. Litingtung, Y., Lei, L., Westphal, H. and Chiang, C. (1998). Sonic hedgehog is essential to foregut development. Nat. Genet. 20, 58-61.
26. Lu, M. M., Yang, H., Zhang, L., Shu, W., Blair, D. G. and Morrisey, E. E. (2001). The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev. Dyn. 222, 667-680.
27. Mason, J. O., Kitajewski, J. and Varmus, H. E. (1992). Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line. Mol. Biol. Cell 3, 521-533.
28. McMahon, A. P. and Moon, R. T. (1989). Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell 58, 1075-1084.
29. Merscher, S., Funke, B., Epstein, J. A., Heyer, J., Puech, A., Lu, M. M., Xavier, R. J., Demay, M. B., Russell, R. G., Factor, S. et al. (2001). TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell 104, 619-629.
30. Miettinen, P. J., Warburton, D., Bu, D., Zhao, J. S., Berger, J. E., Minoo, P., Koivisto, T., Allen, L., Dobbs, L., Werb, Z. et al. (1997). Impaired lung branching morphogenesis in the absence of functional EGF receptor. Dev. Biol. 186, 224-236.
31. Monkley, S. J., Delaney, S. J., Pennisi, D. J., Christiansen, J. H. and Wainwright, B. J. (1996). Targeted disruption of the Wnt2 gene results in placentation defects. Development 122, 3343-3353.
32. Morin, P. J. (1999). beta-catenin signaling and cancer. BioEssays 21, 1021-1030.
33. Mullor, J. L., Dahmane, N., Sun, T. and Ruiz i Altaba, A. (2001). Wnt signals are targets and mediators of Gli function. Cur.r Biol. 11, 769-773.
34. Murray, N. R., Davidson, L. A., Chapkin, R. S., Clay Gustafson, W., Schattenberg, D. G. and Fields, A. P. (1999). Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis. J. Cell Biol. 145, 699-711.
35. Nielsen, H., Engelbrecht, J., Brunak, S. and von Heijne, G. (1997). Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1-6.
36. Nogee, L. M., Garnier, G., Dietz, H. C., Singer, L., Murphy, A. M., deMello, D. E. and Colten, H. R. (1994). A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds. J. Clin. Invest. 93, 1860-1863.
37. Parr, B. A., Cornish, V. A., Cybulsky, M. I. and McMahon, A. P. (2001). Wnt7b regulates placental development in mice. Dev. Biol. 237, 324-332.
38. Parr, B. A. and McMahon, A. P. (1994). Wnt genes and vertebrate development. Curr Opin. Genet. Dev. 4, 523-528.
39. Parr, B. A., Shea, M. J., Vassileva, G. and McMahon, A. P. (1993). Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.
40. Pepicelli, C. V., Lewis, P. M. and McMahon, A. P. (1998). Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol 8, 1083-1086.
41. Reya, T., O'Riordan, M., Okamura, R., Devaney, E., Willert, K., Nusse, R. and Grosschedl, R. (2000). Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 13, 15-24.
42. Rubenstein, J. L., Anderson, S., Shi, L., Miyashita-Lin, E., Bulfone, A. and Hevner, R. (1999). Genetic control of cortical regionalization and connectivity. Cereb. Cortex 9, 524-532.
43. Saka, Y. and Smith, J. C. (2001). Spatial and temporal patterns of cell division during early Xenopus embryogenesis. Dev. Biol. 229, 307-318.
44. Strobeck, M., Kim, S., Zhang, J. C., Clendenin, C., Du, K. L. and Parmacek, M. S. (2001). Binding of serum response factor to CArG box sequences is necessary but not sufficient to restrict gene expression to arterial smooth muscle cells. J. Biol. Chem. 276, 16418-16424.
45. Van den Berg, D. J., Sharma, A. K., Bruno, E. and Hoffman, R. (1998). Role of members of the Wnt gene family in human hematopoiesis. Blood 92, 3189-3202.
46. Wang, X., Xiao, Y., Mou, Y., Zhao, Y., Blankesteijn, W. M. and Hall, J. L. (2002). A role for the beta-catenin/T-cell factor signaling cascade in vascular remodeling. Circ. Res. 90, 340-347.
47. Warburton, D., Schwarz, M., Tefft, D., Flores-Delgado, G., Anderson, K. D. and Cardoso, W. V. (2000). The molecular basis of lung morphogenesis. Mech. Dev. 92, 55-81.
48. Weaver, M., Yingling, J. M., Dunn, N. R., Bellusci, S. and Hogan, B. L. (1999). Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development 126, 4005-4015.
49. Weidenfeld, J., Shu, W., Zhang, L., Millar, S. E. and Morrisey, E. E. (2002). The WNT7B Promoter is Regulated by TTF-1, GATA6, and Foxa2 in Lung Epithelium. J. Biol. Chem. (in press).
50. Willert, K. and Nusse, R. (1998). Beta-catenin: a key mediator of Wnt signaling. Curr Opin. Genet. Dev. 8, 95-102.
51. Wodarz, A. and Nusse, R. (1998). Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14, 59-88.
52. Wong, M. H., Rubinfeld, B. and Gordon, J. I. (1998). Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis. J. Cell Biol. 141, 765-777.
53. Yamaguchi, T. P., Bradley, A., McMahon, A. P. and Jones, S. (1999). A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126, 1211-1223.
54. Yang, H., Lu, M. M., Zhang, L., Wbitsett, J. A. and Morrisey, E. E. (2002). GATA6 regulates differentiation of distal lung epithelium. Development 129, (in press).
55. Zhang, J. C., Kim, S., Helmke, B. P., Yu, W. W., Du, K. L., Lu, M. M., Strobeck, M., Yu, Q. and Parmacek, M. S. (2001). Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function. Mol. Cell. Biol. 21, 1336-1344.