Structure and activity of NO synthase inhibitors specific to the L-arginine binding site

Biochemistry (Moscow)

Volumn 70, Issue 1, 2005, Pages 8-23

  Proskuryakov, S Ya ^a   Konoplyannikov, A G ^a   Skvortsov, V G ^a   Mandrugin, A A ^b   Fedoseev, V M ^b  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Activity and selectivity of NOS inhibitors; Chemical structure; Nitric oxide synthase (NOS); NOS activity regulation; Reactive oxygen species; Substrate like inhibitors

Indexed keywords

BINDING ENERGY; BIOSYNTHESIS; DIMERIZATION; OXYGEN; PROTEINS; REACTION KINETICS; SUBSTRATES;

ACTIVITY AND SELECTIVITY OF NOS INHIBITORS; NITRIC OXIDE SYNTHASE (NOS); NOS ACTIVITY REGULATION; REACTIVE OXYGEN SPECIES; SUBSTRATE-LIKE INHIBITORS;

ENZYME INHIBITION;

ARGININE; ENZYME INHIBITOR; ISOENZYME; NITRIC OXIDE SYNTHASE;

ANIMAL; BINDING SITE; CHEMISTRY; COENZYME; DRUG ANTAGONISM; HUMAN; METABOLISM; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; ARGININE; BINDING SITES; COENZYMES; ENZYME INHIBITORS; HUMANS; ISOENZYMES; NITRIC OXIDE SYNTHASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 14844310339     PISSN: 00062979     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10541-005-0002-x     Document Type: Review

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