2-amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo

British Journal of Pharmacology

Volumn 119, Issue 6, 1996, Pages 1101-1108

  Faraci, W Stephen ^a   Nagel, Arthur A ^a   Verdries, Kimberly A ^a   Vincent, Lawrence A ^a   Xu, Hong ^a   Nichols, Lois E ^a   Labasi, Jeffrey M ^a   Salter, Eben D ^a   Pettipher, E Roy ^a  

^a PFIZER INC   (United States)

Author keywords

2 amino 4 methylpyridine; Endotoxin; Inflammation; Nitric oxide synthase inhibitors; Nitric oxide synthases

Indexed keywords

2 AMINO 4 PICOLINE; AMINOGUANIDINE; ARGININE; ARGININE DERIVATIVE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; LYSINE DERIVATIVE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CELL CULTURE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; ENZYME KINETICS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MACROPHAGE; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029903915     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16010.x     Document Type: Article

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