Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoalkyl]aminopentyl)-N′-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase

Journal of Medicinal Chemistry

Volumn 44, Issue 16, 2001, Pages 2667-2670

  Hah, J M ^a   Roman, L J ^b   Martasek P ^b   Silverman, R B ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N [4 AMINO 5 (AMINOETHYL)AMINOPENTYL] N' NITROGUANIDINE; NITRIC OXIDE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS;

ANIMALS; CATTLE; DIPEPTIDES; ENZYME INHIBITORS; ESCHERICHIA COLI; GUANIDINES; KINETICS; MICE; MOLECULAR MIMICRY; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; RATS; RECOMBINANT PROTEINS; STEREOISOMERISM;

EID: 0035797359     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0101491     Document Type: Article

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