메뉴 건너뛰기




Volumn 28, Issue 10, 2000, Pages 1495-1506

Nitric oxide (NO)-related pharmaceuticals: Contemporary approaches to therapeutic no modulation

Author keywords

Drug discovery and development; Free radical; Gastrointestinal toxicity; Nitric oxide; Nonsteroidal anti inflammatory drug; Pharmaceuticals; Restenosis; Sexual dysfunction

Indexed keywords

CYCLIC GMP; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; SILDENAFIL;

EID: 0034656835     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00247-1     Document Type: Conference Paper
Times cited : (57)

References (96)
  • 1
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial muscle by acetylcholine
    • Furchgott R.F., Zawadski J.V. The obligatory role of endothelial cells in the relaxation of arterial muscle by acetylcholine. Nature. 288:1980;373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadski, J.V.2
  • 2
    • 0032252190 scopus 로고    scopus 로고
    • Nobel Prize awarded to scientists for nitric oxide discoveries
    • SoRelle R. Nobel Prize awarded to scientists for nitric oxide discoveries. Circulation. 98:1998;2365-2366.
    • (1998) Circulation , vol.98 , pp. 2365-2366
    • Sorelle, R.1
  • 5
    • 0030694038 scopus 로고    scopus 로고
    • Biosynthesis and action of nitric oxide in mammalian cells
    • Mayer B., Hemmens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem. Sci. 22:1997;477-481.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 477-481
    • Mayer, B.1    Hemmens, B.2
  • 7
    • 0032910873 scopus 로고    scopus 로고
    • Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: Implications in inflammation
    • Grisham M.B., Jourd'Heuil D., Wink D.A. Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites implications in inflammation . Am. J. Physiol. 276:1999;G315-G321.
    • (1999) Am. J. Physiol. , vol.276 , pp. 315-G321
    • Grisham, M.B.1    Jourd'Heuil, D.2    Wink, D.A.3
  • 8
    • 0031195049 scopus 로고    scopus 로고
    • Reactivity of nitrogen monoxide species with NADH: Implications for nitric oxide-dependent posttranslational protein modification
    • Ewing J.F., Janero D.R., Grinnell T.A., Schroeder J.D., Garvey D.S. Reactivity of nitrogen monoxide species with NADH implications for nitric oxide-dependent posttranslational protein modification . Arch. Biochem. Biophys. 343:1997;131-139.
    • (1997) Arch. Biochem. Biophys. , vol.343 , pp. 131-139
    • Ewing, J.F.1    Janero, D.R.2    Grinnell, T.A.3    Schroeder, J.D.4    Garvey, D.S.5
  • 9
    • 0032902722 scopus 로고    scopus 로고
    • Guanylate cyclase and the NO/cGMP signaling pathway
    • Denninger J.W., Marletta M.A. Guanylate cyclase and the NO/cGMP signaling pathway. Biochim. Biophys. Acta. 1411:1999;334-350.
    • (1999) Biochim. Biophys. Acta , vol.1411 , pp. 334-350
    • Denninger, J.W.1    Marletta, M.A.2
  • 10
    • 0031623305 scopus 로고    scopus 로고
    • Nitric oxide signaling: Would you believe that a simple free radical could be a second messenger, autacoid, paracrine substance, neurotransmitter, and hormone?
    • Murad F. Nitric oxide signaling would you believe that a simple free radical could be a second messenger, autacoid, paracrine substance, neurotransmitter, and hormone? Recent Prog. Horm. Res. 53:1998;43-60.
    • (1998) Recent Prog. Horm. Res. , vol.53 , pp. 43-60
    • Murad, F.1
  • 11
    • 0032464635 scopus 로고    scopus 로고
    • Pathophysiology of nitric oxide and related species: Free radical reactions and modification of biomolecules
    • Eiserich J.P., Patel R.P., O'Donnell V.B. Pathophysiology of nitric oxide and related species free radical reactions and modification of biomolecules . Mol. Aspects Med. 19:1998;221-357.
    • (1998) Mol. Aspects Med. , vol.19 , pp. 221-357
    • Eiserich, J.P.1    Patel, R.P.2    O'Donnell, V.B.3
  • 12
    • 0032171425 scopus 로고    scopus 로고
    • The basic chemistry of nitrogen monoxide and peroxynitrite
    • Koppenol W.H. The basic chemistry of nitrogen monoxide and peroxynitrite. Free Radic. Biol. Med. 25:1998;385-391.
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 385-391
    • Koppenol, W.H.1
  • 13
    • 0026490231 scopus 로고
    • Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide
    • Lepoivre M., Flaman J.M., Henry Y. Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide. J. Biol. Chem. 267:1992;22994-23000.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22994-23000
    • Lepoivre, M.1    Flaman, J.M.2    Henry, Y.3
  • 14
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • Wink D.A., Mitchell J.B. Chemical biology of nitric oxide insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide . Free Radic. Biol. Med. 25:1998;434-456.
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 15
    • 0344936731 scopus 로고    scopus 로고
    • Nitric oxide: Cytoxicity versus cytoprotection - how, why, when, and where?
    • Kröncke K.-D., Fehsel K., Kolb-Bachofen V. Nitric oxide cytoxicity versus cytoprotection - how, why, when, and where? Nitric Oxide Biol. Chem. 1:1997;107-120.
    • (1997) Nitric Oxide Biol. Chem. , vol.1 , pp. 107-120
    • Kröncke, K.-D.1    Fehsel, K.2    Kolb-Bachofen, V.3
  • 17
    • 0032951905 scopus 로고    scopus 로고
    • Nitric oxide and iron proteins
    • Cooper C.E. Nitric oxide and iron proteins. Biochim. Biophys. Acta. 1411:1999;290-309.
    • (1999) Biochim. Biophys. Acta , vol.1411 , pp. 290-309
    • Cooper, C.E.1
  • 18
    • 0001149069 scopus 로고    scopus 로고
    • The chemistry of peroxynitrite and peroxynitrous acid: Products from the reaction of nitric oxide with superoxide
    • Pryor W.A., Squadrito G.L. The chemistry of peroxynitrite and peroxynitrous acid products from the reaction of nitric oxide with superoxide . Am. J. Physiol. 268:1996;L699-L721.
    • (1996) Am. J. Physiol. , vol.268 , pp. 699-L721
    • Pryor, W.A.1    Squadrito, G.L.2
  • 19
    • 0025837118 scopus 로고
    • Hydrogen peroxide-induced oxidative stress to the mammalian heart-muscle cell (cardiomyocyte); Lethal peroxidative membrane injury
    • Janero D.R., Hreniuk D., Sharif H.A. Hydrogen peroxide-induced oxidative stress to the mammalian heart-muscle cell (cardiomyocyte); lethal peroxidative membrane injury. J. Cell. Physiol. 149:1991;347-364.
    • (1991) J. Cell. Physiol. , vol.149 , pp. 347-364
    • Janero, D.R.1    Hreniuk, D.2    Sharif, H.A.3
  • 20
  • 24
    • 0032426602 scopus 로고    scopus 로고
    • Inflammation, lipids, and free radicals: Lessons learned from the atherogenic process
    • Rosenfeld M.E. Inflammation, lipids, and free radicals lessons learned from the atherogenic process . Semin. Reprod. Endocrinol. 16:1998;249-261.
    • (1998) Semin. Reprod. Endocrinol. , vol.16 , pp. 249-261
    • Rosenfeld, M.E.1
  • 26
    • 0032797262 scopus 로고    scopus 로고
    • Nitric oxide synthases: Targets for therapeutic strategies in neurological diseases
    • Chabrier P.E., Demerlé Pallardy C., Auget M. Nitric oxide synthases targets for therapeutic strategies in neurological diseases . Cell. Mol. Life Sci. 55:1999;1029-1035.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1029-1035
    • Chabrier, P.E.1    Demerlé Pallardy, C.2    Auget, M.3
  • 27
    • 0032200944 scopus 로고    scopus 로고
    • Nitric oxide in allergic rhinitis and asthma
    • Frieri M. Nitric oxide in allergic rhinitis and asthma. Allergy Asthma Proc. 19:1998;349-351.
    • (1998) Allergy Asthma Proc. , vol.19 , pp. 349-351
    • Frieri, M.1
  • 28
    • 0031900542 scopus 로고    scopus 로고
    • Role of nitric oxide in tumor progression: Lessons from human tumors
    • Thomsen L.L., Miles D.W. Role of nitric oxide in tumor progression lessons from human tumors . Cancer Metastasis Rev. 17:1998;107-118.
    • (1998) Cancer Metastasis Rev. , vol.17 , pp. 107-118
    • Thomsen, L.L.1    Miles, D.W.2
  • 29
    • 84941138007 scopus 로고
    • Myocardial ischemia-reperfusion injury and the cardioprotective potential of natural antioxidants
    • B. Frei. San Diego: Academic Press
    • Janero D.R. Myocardial ischemia-reperfusion injury and the cardioprotective potential of natural antioxidants. Frei B. Natural antioxidants in human health and disease. 1994;411-445 Academic Press, San Diego.
    • (1994) Natural Antioxidants in Human Health and Disease , pp. 411-445
    • Janero, D.R.1
  • 30
    • 0032776548 scopus 로고    scopus 로고
    • Reperfusion injury: Experimental evidence and clinical implications
    • Ambrosio G., Tritto I. Reperfusion injury experimental evidence and clinical implications . Am. Heart J. 138:1999;69-75.
    • (1999) Am. Heart J. , vol.138 , pp. 69-75
    • Ambrosio, G.1    Tritto, I.2
  • 32
    • 0032998811 scopus 로고    scopus 로고
    • Nitric oxide synthase and cyclooxygenases: Distribution, regulation, and intervention in arthritis
    • Amin A.R., Attur M., Abramson S.B. Nitric oxide synthase and cyclooxygenases distribution, regulation, and intervention in arthritis . Curr. Opin. Rheumatol. 11:1999;202-209.
    • (1999) Curr. Opin. Rheumatol. , vol.11 , pp. 202-209
    • Amin, A.R.1    Attur, M.2    Abramson, S.B.3
  • 33
    • 0033063534 scopus 로고    scopus 로고
    • Nitric oxide. V. Therapeutic potential of nitric oxide donors and inhibitors
    • Muscara M.N., Wallace J.L. Nitric oxide. V. Therapeutic potential of nitric oxide donors and inhibitors. Am. J. Physiol. 276:1999;G1313-G1316.
    • (1999) Am. J. Physiol. , vol.276 , pp. 1313-G1316
    • Muscara, M.N.1    Wallace, J.L.2
  • 34
    • 0032133353 scopus 로고    scopus 로고
    • Design of isoform-selective inhibitors of nitric oxide synthase
    • Babu B.R., Griffith O.W. Design of isoform-selective inhibitors of nitric oxide synthase. Curr. Opin. Chem. Biol. 2:1998;491-500.
    • (1998) Curr. Opin. Chem. Biol. , vol.2 , pp. 491-500
    • Babu, B.R.1    Griffith, O.W.2
  • 35
    • 0342668663 scopus 로고    scopus 로고
    • Medinox moves forward with plan to neutralize NO directly
    • Pihl-Carey K. Medinox moves forward with plan to neutralize NO directly. BioWorld Today. 10:1999;1.
    • (1999) BioWorld Today , vol.10 , pp. 1
    • Pihl-Carey, K.1
  • 36
    • 0030712983 scopus 로고    scopus 로고
    • Nitric oxide and cardiovascular disease
    • McIntyre M., Dominiczak A.F. Nitric oxide and cardiovascular disease. Postgrad. Med. 73:1997;630-634.
    • (1997) Postgrad. Med. , vol.73 , pp. 630-634
    • McIntyre, M.1    Dominiczak, A.F.2
  • 38
    • 0028221190 scopus 로고
    • Role of NO in vascular smooth muscle and cardiac muscle function
    • Shulz R., Triggle C.R. Role of NO in vascular smooth muscle and cardiac muscle function. Trends Pharmacol. Sci. 15:1994;255-259.
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 255-259
    • Shulz, R.1    Triggle, C.R.2
  • 39
    • 0031661735 scopus 로고    scopus 로고
    • Inhaled nitric oxide therapy for pulmonary disease in pediatrics
    • Abman S.H., Kinsella J.P. Inhaled nitric oxide therapy for pulmonary disease in pediatrics. Curr. Opin. Pediatr. 10:1998;236-242.
    • (1998) Curr. Opin. Pediatr. , vol.10 , pp. 236-242
    • Abman, S.H.1    Kinsella, J.P.2
  • 40
    • 0032941593 scopus 로고    scopus 로고
    • Nitric oxide in adult lung disease
    • Hart C.M. Nitric oxide in adult lung disease. Chest. 115:1999;1407-1417.
    • (1999) Chest , vol.115 , pp. 1407-1417
    • Hart, C.M.1
  • 41
    • 0030007350 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus
    • Williams S.B., Cusco J.A., Roddy M.A., Johnstone M.T., Creager M.A. Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J. Am. Coll. Cardiol. 27:1996;567-574.
    • (1996) J. Am. Coll. Cardiol. , vol.27 , pp. 567-574
    • Williams, S.B.1    Cusco, J.A.2    Roddy, M.A.3    Johnstone, M.T.4    Creager, M.A.5
  • 42
    • 0031786851 scopus 로고    scopus 로고
    • Impaired endothelial regulation of vascular tone in patients with systemic arterial hypertension
    • Cardillo C., Panza J.A. Impaired endothelial regulation of vascular tone in patients with systemic arterial hypertension. Vasc. Med. 3:1998;138-144.
    • (1998) Vasc. Med. , vol.3 , pp. 138-144
    • Cardillo, C.1    Panza, J.A.2
  • 44
    • 0030980611 scopus 로고    scopus 로고
    • Coronary risk factors, endothelial function, and atherosclerosis: A review
    • Vogel R.A. Coronary risk factors, endothelial function, and atherosclerosis a review . Clin. Cardiol. 20:1997;426-432.
    • (1997) Clin. Cardiol. , vol.20 , pp. 426-432
    • Vogel, R.A.1
  • 45
    • 0033055559 scopus 로고    scopus 로고
    • Endothelial dysfunction: From physiology to therapy
    • Mombouli J.V., Vanhoutte P.M. Endothelial dysfunction from physiology to therapy . J. Mol. Cell. Cardiol. 31:1999;61-74.
    • (1999) J. Mol. Cell. Cardiol. , vol.31 , pp. 61-74
    • Mombouli, J.V.1    Vanhoutte, P.M.2
  • 46
    • 0018630817 scopus 로고
    • Nitroglycerine - The first one hundred years: New facts about an old drug
    • Parrat J.R. Nitroglycerine - the first one hundred years new facts about an old drug . J. Pharm. Pharmacol. 31:1979;801-809.
    • (1979) J. Pharm. Pharmacol. , vol.31 , pp. 801-809
    • Parrat, J.R.1
  • 47
    • 0031906370 scopus 로고    scopus 로고
    • How toxic is nitric oxide?
    • Gordge M.P. How toxic is nitric oxide? Exp. Nephrol. 6:1998;12-16.
    • (1998) Exp. Nephrol. , vol.6 , pp. 12-16
    • Gordge, M.P.1
  • 48
    • 0032171427 scopus 로고    scopus 로고
    • Specific S-nitrosothiol (thionitrite) quantification as solution nitrite after vanadium(III) reduction and ozone-chemiluminescent detection
    • Ewing J.F., Janero D.R. Specific S-nitrosothiol (thionitrite) quantification as solution nitrite after vanadium(III) reduction and ozone-chemiluminescent detection. Free Radic. Biol. Med. 25:1998;621-628.
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 621-628
    • Ewing, J.F.1    Janero, D.R.2
  • 49
    • 0031866978 scopus 로고    scopus 로고
    • The use of inhaled nitric oxide in a wide variety of clinical problems
    • Nelin K.D., Hoffman G.M. The use of inhaled nitric oxide in a wide variety of clinical problems. Pediatr. Clin. North Am. 45:1998;531-548.
    • (1998) Pediatr. Clin. North Am. , vol.45 , pp. 531-548
    • Nelin, K.D.1    Hoffman, G.M.2
  • 50
    • 0029133926 scopus 로고
    • FK409, a new nitric oxide-donor, suppressed smooth muscle proliferation in the rat model of balloon angioplasty
    • Seki J., Nishio M., Kato Y., Motoyama Y., Yoshida K. FK409, a new nitric oxide-donor, suppressed smooth muscle proliferation in the rat model of balloon angioplasty. Atherosclerosis. 117:1995;97-106.
    • (1995) Atherosclerosis , vol.117 , pp. 97-106
    • Seki, J.1    Nishio, M.2    Kato, Y.3    Motoyama, Y.4    Yoshida, K.5
  • 52
    • 0029821342 scopus 로고    scopus 로고
    • "nONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms
    • Keefer L.K., Nims R.W., Davies K.M., Wink D.A. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors convenient nitric oxide dosage forms . Meth. Enzymol. 268:1996;281-293.
    • (1996) Meth. Enzymol. , vol.268 , pp. 281-293
    • Keefer, L.K.1    Nims, R.W.2    Davies, K.M.3    Wink, D.A.4
  • 53
    • 0031866842 scopus 로고    scopus 로고
    • The use of nitric oxide donors in pharmacological studies
    • Feelisch M. The use of nitric oxide donors in pharmacological studies. Naunyn Schmiedebergs Arch. Pharmacol. 358:1998;113-122.
    • (1998) Naunyn Schmiedebergs Arch. Pharmacol. , vol.358 , pp. 113-122
    • Feelisch, M.1
  • 54
    • 0030732453 scopus 로고    scopus 로고
    • Nitrosylated bovine serum albumin derivatives as pharmacologically active nitric oxide congeners
    • Ewing J.F., Young D.V., Janero D.R., Garvey D.S., Grinnell T.A. Nitrosylated bovine serum albumin derivatives as pharmacologically active nitric oxide congeners. J. Pharmacol. Exp. Ther. 283:1997;947-954.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 947-954
    • Ewing, J.F.1    Young, D.V.2    Janero, D.R.3    Garvey, D.S.4    Grinnell, T.A.5
  • 55
    • 0344761974 scopus 로고    scopus 로고
    • The epidemiology and pathophysiology of erectile dysfunction
    • Melman A., Gingell J.C. The epidemiology and pathophysiology of erectile dysfunction. J. Urol. 161:1999;5-11.
    • (1999) J. Urol. , vol.161 , pp. 5-11
    • Melman, A.1    Gingell, J.C.2
  • 57
    • 0342668658 scopus 로고    scopus 로고
    • Anatomy of the penis and elementary physiology of erection
    • H. Porst. New York: Springer-Verlag
    • Juneman K.P. Anatomy of the penis and elementary physiology of erection. Porst H. Penile disorders. 1996;1-12 Springer-Verlag, New York.
    • (1996) Penile Disorders , pp. 1-12
    • Juneman, K.P.1
  • 58
    • 0033050763 scopus 로고    scopus 로고
    • Molecular mechanisms of the effects of sildenafil (Viagra)
    • Glossmann H., Petrischor G., Bartsch G. Molecular mechanisms of the effects of sildenafil (Viagra). Exp. Gerontol. 34:1999;305-318.
    • (1999) Exp. Gerontol. , vol.34 , pp. 305-318
    • Glossmann, H.1    Petrischor, G.2    Bartsch, G.3
  • 59
    • 0343974659 scopus 로고    scopus 로고
    • ICOS receives $15M milestone but also has two failed trials
    • Welch M. ICOS receives $15M milestone but also has two failed trials. BioWorld Today. 10:1999;1.
    • (1999) BioWorld Today , vol.10 , pp. 1
    • Welch, M.1
  • 60
    • 0032976391 scopus 로고    scopus 로고
    • Sildenafil in the treatment of female sexual dysfunction induced by selective serotonin reuptake inhibitors
    • Shen W.W., Urosevich Z., Clayton D.O. Sildenafil in the treatment of female sexual dysfunction induced by selective serotonin reuptake inhibitors. J. Reprod. Med. 44:1999;535-542.
    • (1999) J. Reprod. Med. , vol.44 , pp. 535-542
    • Shen, W.W.1    Urosevich, Z.2    Clayton, D.O.3
  • 64
    • 0025272553 scopus 로고
    • Interventions in acute myocardial infarction
    • Ellis S.G. Interventions in acute myocardial infarction. Circulation. 81:1990;IV43-IV50.
    • (1990) Circulation , vol.81 , pp. 43-IV50
    • Ellis, S.G.1
  • 65
    • 0032169308 scopus 로고    scopus 로고
    • Beyond stents: Third-generation coronary devices
    • Oesterle S.N. Beyond stents third-generation coronary devices . Ann. Thorac. Surg. 66:1998;1045-1049.
    • (1998) Ann. Thorac. Surg. , vol.66 , pp. 1045-1049
    • Oesterle, S.N.1
  • 67
    • 0029841101 scopus 로고    scopus 로고
    • Intracoronary stenting. From concept to custom
    • Ruygrok P.N., Serruys P.W. Intracoronary stenting. From concept to custom. Circulation. 94:1996;882-890.
    • (1996) Circulation , vol.94 , pp. 882-890
    • Ruygrok, P.N.1    Serruys, P.W.2
  • 68
    • 0030071717 scopus 로고    scopus 로고
    • Chronic inhalation of nitric oxide inhibits neointimal formation after balloon-induced arterial injury
    • Lee J.S., Adrie C., Jacob H.J., Roberts J.D. Jr, Zapol W.M., Bloch K.D. Chronic inhalation of nitric oxide inhibits neointimal formation after balloon-induced arterial injury. Circ. Res. 78:1996;337-342.
    • (1996) Circ. Res. , vol.78 , pp. 337-342
    • Lee, J.S.1    Adrie, C.2    Jacob, H.J.3    Roberts J.D., Jr.4    Zapol, W.M.5    Bloch, K.D.6
  • 69
    • 0032975499 scopus 로고    scopus 로고
    • Continuous perivascular L-arginine delivery increases total vessel area and reduces neointimal thickening after experimental balloon dilatation
    • Bosmans J.M., Vrints C.J., Kocks M.M., Bult H., Cromheeke K.M.C., Herman A.G. Continuous perivascular L-arginine delivery increases total vessel area and reduces neointimal thickening after experimental balloon dilatation. Arteriosclero. Thromb. Vasc. Biol. 19:1999;767-776.
    • (1999) Arteriosclero. Thromb. Vasc. Biol. , vol.19 , pp. 767-776
    • Bosmans, J.M.1    Vrints, C.J.2    Kocks, M.M.3    Bult, H.4    Cromheeke, K.M.C.5    Herman, A.G.6
  • 70
    • 0028787682 scopus 로고
    • Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide
    • Marks D.S., Vita J.A., Folts J.D., Keaney J.F. Jr, Welch G.N., Loscalzo J. Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide. J. Clin. Invest. 96:1995;2630-2638.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2630-2638
    • Marks, D.S.1    Vita, J.A.2    Folts, J.D.3    Keaney J.F., Jr.4    Welch, G.N.5    Loscalzo, J.6
  • 72
    • 0032559625 scopus 로고    scopus 로고
    • Gene therapy for restenosis. Are we ready?
    • De Young M.B., Dichek D.A. Gene therapy for restenosis. Are we ready? Circ. Res. 82:1998;306-313.
    • (1998) Circ. Res. , vol.82 , pp. 306-313
    • De Young, M.B.1    Dichek, D.A.2
  • 73
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study
    • Murray C.J.L., Lopez A.D. Alternative projections of mortality and disability by cause 1990-2020 global burden of disease study . Lancet. 349:1997;1498-1504.
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.L.1    Lopez, A.D.2
  • 74
    • 10544225381 scopus 로고    scopus 로고
    • Gastrointestinal effects of NSAIDs. Difficulties in detection and management
    • Pearson S.P., Kelberman I. Gastrointestinal effects of NSAIDs. Difficulties in detection and management. Postgrad. Med. 100:1996;131-143.
    • (1996) Postgrad. Med. , vol.100 , pp. 131-143
    • Pearson, S.P.1    Kelberman, I.2
  • 75
    • 0028641257 scopus 로고
    • Mechanisms of nonsteroidal anti-inflammatory drug (NSAID) induced gastrointestinal damage - potential for development of gastrointestinal tract safe NSAIDs
    • Wallace J.L. Mechanisms of nonsteroidal anti-inflammatory drug (NSAID) induced gastrointestinal damage - potential for development of gastrointestinal tract safe NSAIDs. Can. J. Physiol. Pharmacol. 72:1994;1493-1498.
    • (1994) Can. J. Physiol. Pharmacol. , vol.72 , pp. 1493-1498
    • Wallace, J.L.1
  • 76
    • 0029953816 scopus 로고    scopus 로고
    • The cellular and molecular basis of gastric mucosal defense
    • Wallace J.L., Grangier N. The cellular and molecular basis of gastric mucosal defense. FASEB J. 10:1996;731-740.
    • (1996) FASEB J. , vol.10 , pp. 731-740
    • Wallace, J.L.1    Grangier, N.2
  • 78
    • 0030918695 scopus 로고    scopus 로고
    • Nitric oxide-releasing nonsteroidal antiinflammatory drugs: A new generation of antithrombotics?
    • Wallace J.L., Del Soldato P., Cirino G. Nitric oxide-releasing nonsteroidal antiinflammatory drugs a new generation of antithrombotics? Expert Opinion on Investigational Drugs. 6:1997;533-538.
    • (1997) Expert Opinion on Investigational Drugs , vol.6 , pp. 533-538
    • Wallace, J.L.1    Del Soldato, P.2    Cirino, G.3
  • 82
    • 0033524687 scopus 로고    scopus 로고
    • Potential role of a membrane-bound NADH oxidoreductase in nitric oxide release and arterial relaxation to nitroprusside
    • Mohazzab-H K.M., Kaminski P.M., Agarwal R., Wolin M.S. Potential role of a membrane-bound NADH oxidoreductase in nitric oxide release and arterial relaxation to nitroprusside. Circ. Res. 84:1999;220-228.
    • (1999) Circ. Res. , vol.84 , pp. 220-228
    • Mohazzab-H, K.M.1    Kaminski, P.M.2    Agarwal, R.3    Wolin, M.S.4
  • 86
    • 0343538864 scopus 로고    scopus 로고
    • Acquisition allows Apex, shock drug to move ahead
    • Welch M. Acquisition allows Apex, shock drug to move ahead. BioWorld Today. 10:1999;1.
    • (1999) BioWorld Today , vol.10 , pp. 1
    • Welch, M.1
  • 87
    • 0342668648 scopus 로고    scopus 로고
    • NicOx launches $34M IPO to speed up its R&D efforts
    • Etheridge J. NicOx launches $34M IPO to speed up its R&D efforts. BioWorld International. 4:1999;3.
    • (1999) BioWorld International , vol.4 , pp. 3
    • Etheridge, J.1
  • 88
    • 0343102950 scopus 로고    scopus 로고
    • NitroMed to Target Black CHF Patients with BiDil
    • NitroMed to Target Black CHF Patients with BiDil. SCRIP Number 2475:3; 1999.
    • (1999) SCRIP Number , vol.2475 , pp. 3
  • 89
    • 0343974653 scopus 로고    scopus 로고
    • NitroMed signs two research pacts with Johnson & Johnson
    • Bishop F. NitroMed signs two research pacts with Johnson & Johnson. BioWorld Today. 8:1997;1.
    • (1997) BioWorld Today , vol.8 , pp. 1
    • Bishop, F.1
  • 90
    • 0343102951 scopus 로고    scopus 로고
    • Johnson & Johnson/NitroMed Partner to Develop NSAIs
    • Johnson & Johnson/NitroMed Partner to Develop NSAIs. SCRIP Number 2223:15; 1997.
    • (1997) SCRIP Number , vol.2223 , pp. 15
  • 91
  • 93
    • 0032942042 scopus 로고    scopus 로고
    • Basic science and pharmaceutical innovation
    • Drews J. Basic science and pharmaceutical innovation. Nat. Biotechnol. 17:1999;406.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 406
    • Drews, J.1
  • 94
    • 0343974652 scopus 로고    scopus 로고
    • NicOx to start first US trials
    • NicOx to start first US trials. SCRIP Number 2513:18; 2000.
    • (2000) SCRIP Number , vol.2513 , pp. 18
  • 95
    • 0343974651 scopus 로고    scopus 로고
    • Other News to Note. NicOx SA
    • Other News to Note. NicOx SA. BioWorld Today 11:3; 2000.
    • (2000) BioWorld Today , vol.11 , pp. 3
  • 96
    • 0343974650 scopus 로고    scopus 로고
    • Other News to Note. NicOx SA
    • Other News to Note. NicOx SA. BioWorld International 5:4; 2000.
    • (2000) BioWorld International , vol.5 , pp. 4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.