메뉴 건너뛰기




Volumn 312, Issue 3, 1996, Pages 341-347

S-Substituted isothioureas are potent inhibitors of nitric oxide biosynthesis in cartilage

Author keywords

Arthritis; Cartilage; Chondrocyte; Free radical; Inducible; Nitric oxide (NO) synthase

Indexed keywords

AMINOGUANIDINE; N(G) METHYLARGININE; N(G) NITROARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; S METHYLPSEUDOTHIOUREA; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0030567955     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00369-X     Document Type: Article
Times cited : (24)

References (24)
  • 2
    • 0026576899 scopus 로고
    • Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter
    • Bogle, R.G., S. Moncada, J.D. Pearson and G.E. Mann, 1992, Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter, Br. J. Pharmacol. 105, 768.
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 768
    • Bogle, R.G.1    Moncada, S.2    Pearson, J.D.3    Mann, G.E.4
  • 4
    • 0026467074 scopus 로고
    • Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases
    • Farrell, A.J., D.R. Blake, R.M. Palmer and S. Moncada, 1992, Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases, Ann. Rheum. Dis. 51, 1219.
    • (1992) Ann. Rheum. Dis. , vol.51 , pp. 1219
    • Farrell, A.J.1    Blake, D.R.2    Palmer, R.M.3    Moncada, S.4
  • 6
    • 0024210874 scopus 로고
    • Interleukin 1 suppresses expression of cartilage-specific Types II and IX collagens and increases type I and III collagens in human chondrocytes
    • Goldring, S.B., J. Birkhead, L.J. Sandell, T. Kimura and S.M. Krane, 1988, Interleukin 1 suppresses expression of cartilage-specific Types II and IX collagens and increases type I and III collagens in human chondrocytes, J. Clin. Invest. 82, 2026.
    • (1988) J. Clin. Invest. , vol.82 , pp. 2026
    • Goldring, S.B.1    Birkhead, J.2    Sandell, L.J.3    Kimura, T.4    Krane, S.M.5
  • 7
    • 0015025415 scopus 로고
    • Behaviour of articular chondrocytes in cell culture
    • Green, W.T., 1971, Behaviour of articular chondrocytes in cell culture, Clin. Orthop. 75, 248.
    • (1971) Clin. Orthop. , vol.75 , pp. 248
    • Green, W.T.1
  • 8
    • 0026323665 scopus 로고
    • Purification of the inducible murine macrophage nitric oxide synthase
    • Hevel, J.M., K.A. White and M.A. Marletta, 1991, Purification of the inducible murine macrophage nitric oxide synthase, J. Biol. Chem. 266, 22789.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22789
    • Hevel, J.M.1    White, K.A.2    Marletta, M.A.3
  • 11
    • 0029992922 scopus 로고    scopus 로고
    • Nitric oxide enhances cyclooxygenase activity in articular cartilage
    • Manfield, L., D. Jang and G.A.C. Murrell, 1996, Nitric oxide enhances cyclooxygenase activity in articular cartilage, Inflamm. Res. 45, 254.
    • (1996) Inflamm. Res. , vol.45 , pp. 254
    • Manfield, L.1    Jang, D.2    Murrell, G.A.C.3
  • 14
    • 0028872942 scopus 로고
    • Nitric oxide activates metalloprotease activity in articular cartilage
    • Murrell, G.A.C., D. Jang and R.J. Williams, 1995b, Nitric oxide activates metalloprotease activity in articular cartilage, Biochem. Biophys. Res. Commun. 206, 15.
    • (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 15
    • Murrell, G.A.C.1    Jang, D.2    Williams, R.J.3
  • 16
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage microbial activity
    • Nathan, C.F. and J.B. Hibbs, 1991, Role of nitric oxide synthesis in macrophage microbial activity, Curr. Opin. Immunol. 3, 65.
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 65
    • Nathan, C.F.1    Hibbs, J.B.2
  • 18
    • 0025327911 scopus 로고
    • Synthesis of a nitric oxide factor from L-arginine by rat serosal mast cells: Stimulation of guanylate cyclase and inhibition of platelet aggregation
    • Salvemini, D., E. Masini, E. Änggård, P.F. Mannaioni and J. Vane, 1990, Synthesis of a nitric oxide factor from L-arginine by rat serosal mast cells: stimulation of guanylate cyclase and inhibition of platelet aggregation, Biochem. Biophys. Res. Commun. 169, 596.
    • (1990) Biochem. Biophys. Res. Commun. , vol.169 , pp. 596
    • Salvemini, D.1    Masini, E.2    Änggård, E.3    Mannaioni, P.F.4    Vane, J.5
  • 20
    • 0028848015 scopus 로고
    • Isothioureas: Potent inhibitors of nitric oxide synthases with variable isoform selectivity
    • Southan, G.J., C. Szabo and C. Thiemermann, 1995, Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity, Br. J. Pharmacol. 114, 510.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 510
    • Southan, G.J.1    Szabo, C.2    Thiemermann, C.3
  • 22
    • 0028945506 scopus 로고
    • Alterations in nitric oxide production in various forms of circulatory shock
    • Szabo, C., 1995, Alterations in nitric oxide production in various forms of circulatory shock, New Horizons 3, 2.
    • (1995) New Horizons , vol.3 , pp. 2
    • Szabo, C.1
  • 23
    • 0028577721 scopus 로고
    • Beneficial effects and improved survival in rodent models of septic shock with S-methyl-isothioures sulfate, a novel, potent and selective inhibitor of inducible nitric oxide synthase
    • Szabo, C., G.J. Southan and C. Thiemermann, 1994, Beneficial effects and improved survival in rodent models of septic shock with S-methyl-isothioures sulfate, a novel, potent and selective inhibitor of inducible nitric oxide synthase, Proc. Natl. Acad. Sci. USA 91, 12472.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12472
    • Szabo, C.1    Southan, G.J.2    Thiemermann, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.