Selective inhibition of neuronal nitric oxide synthase by N(ω)- nitroarginine- and phenylalanine-containing dipeptides and dipeptide esters

Journal of Medicinal Chemistry

Volumn 40, Issue 18, 1997, Pages 2813-2817

  Silverman, Richard B ^a   Huang, Hui ^a   Marletta, Michael A ^b   Martasek, Pavel ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE; CALCIUM CHLORIDE; CALMODULIN; DITHIOTHREITOL; ESTER DERIVATIVE; N(G) METHYLARGININE; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; OXYHEMOGLOBIN; PHENYLALANINE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRAHYDROBIOPTERIN; TRIFLUOROACETIC ACID;

ARTICLE; CHIRALITY; COMPETITIVE INHIBITION; DRUG SELECTIVITY; ENDOTHELIUM CELL; ENZYME INHIBITION; MACROPHAGE;

ANIMALS; BRAIN; CATTLE; DIPEPTIDES; ENZYME INHIBITORS; ETHERS; KINETICS; NEURONS; NITRIC OXIDE SYNTHASE; NITROARGININE; PHENYLALANINE; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030773013     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970200u     Document Type: Article

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