Nitric oxide synthase generates Superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 13, 1996, Pages 6770-6774

  Xia, Yong ^a   Dawson, Valina L ^b   Dawson, Ted M ^b   Snyder, Solomon H ^b   Zweier, Jay L ^a  

^a Department of Medicine   (United States)

^b JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

Author keywords

Electron paramagnetic resonance; Free radicals; Nitrotyrosine; Spin trapping

Indexed keywords

3 NITROTYROSINE; ARGININE; CALCIMYCIN; LACTATE DEHYDROGENASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXIDE; PEROXYNITRITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL DAMAGE; CONTROLLED STUDY; CYTOTOXICITY; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL;

ARGININE; CELL LINE; ENZYME INHIBITORS; HUMANS; L-LACTATE DEHYDROGENASE; NG-NITROARGININE METHYL ESTER; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDES;

EID: 0029900905     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.13.6770     Document Type: Article

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