Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage

Journal of Biological Chemistry

Volumn 272, Issue 14, 1997, Pages 9030-9036

  Szabó, Csaba ^a   Ferrer Sueta, Gerardo ^b,c   Zingarelli, Basilia ^a   Southan, Garry J ^a   Salzman, Andrew L ^a   Radi, Rafael ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^c CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GUANIDINE; GUANIDINE DERIVATIVE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CYTOPATHOGENIC EFFECT; DNA STRAND BREAKAGE; DRUG EFFECT; ENZYME INHIBITION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; CELL LINE; ENZYME INHIBITORS; GUANIDINES; KINETICS; MODELS, CHEMICAL; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NITRATES; NITRIC OXIDE SYNTHASE; NOREPINEPHRINE; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; RATS; VASOCONSTRICTOR AGENTS;

EID: 0030938584     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.14.9030     Document Type: Article

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