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Volumn 28, Issue 10, 2000, Pages 1470-1477

Discovery and development of neuronal nitric oxide synthase inhibitors

Author keywords

Antioxidant; Free radical; Ischemia; Neuroprotectant; Nitric oxide; Peroxynitrite

Indexed keywords

FREE RADICAL; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE;

EID: 0034656844     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00250-1     Document Type: Conference Paper
Times cited : (38)

References (31)
  • 1
    • 0033600277 scopus 로고    scopus 로고
    • The changing landscape of ischemic brain injury
    • Lee J.-M., Zipfel G.J., Choi D.W. The changing landscape of ischemic brain injury. Nature. 399:1999;A7-A14.
    • (1999) Nature , vol.399 , pp. 7-A14
    • Lee, J.-M.1    Zipfel, G.J.2    Choi, D.W.3
  • 2
    • 0028799654 scopus 로고
    • Calcium: Still center-stage in hypoxic-ischemic neuronal death
    • Choi D.W. Calcium still center-stage in hypoxic-ischemic neuronal death . Trends Neurosci. 18:1995;58-60.
    • (1995) Trends Neurosci. , vol.18 , pp. 58-60
    • Choi, D.W.1
  • 3
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischemic stroke: An integrated view
    • Dirnagl U., Iadecola C., Moskowitz M.A. Pathobiology of ischemic stroke an integrated view . Trends Neurosci. 22:1999;391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 5
    • 0032930417 scopus 로고    scopus 로고
    • Mammalian nitric oxide synthases
    • Stuehr D.J. Mammalian nitric oxide synthases. Biochim. Biophys. Acta. 1411:1999;217-230.
    • (1999) Biochim. Biophys. Acta , vol.1411 , pp. 217-230
    • Stuehr, D.J.1
  • 6
    • 0025731384 scopus 로고
    • Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes
    • Stadler J., Billiar T.R., Curran R.D., Stuehr D.J., Ochoa J.B., Simmons R.L. Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol. 260:1991;C910-C916.
    • (1991) Am. J. Physiol. , vol.260 , pp. 910-C916
    • Stadler, J.1    Billiar, T.R.2    Curran, R.D.3    Stuehr, D.J.4    Ochoa, J.B.5    Simmons, R.L.6
  • 7
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity
    • Zhang J., Dawson V.L., Dawson T.M., Snyder S.H. Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science. 263:1994;687-689.
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 8
    • 0025854274 scopus 로고
    • The double-edged role of nitric oxide in brain function and superoxide-mediated injury
    • Beckman J.S. The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J. Dev. Physiol. 15:1991;53-59.
    • (1991) J. Dev. Physiol. , vol.15 , pp. 53-59
    • Beckman, J.S.1
  • 9
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly
    • Beckman J.S., Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite the good, the bad, and the ugly . Am. J. Physiol. 271:1996;C1424-C1437.
    • (1996) Am. J. Physiol. , vol.271 , pp. 1424-C1437
    • Beckman, J.S.1    Koppenol, W.H.2
  • 10
    • 0027945658 scopus 로고
    • Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
    • Huang Z., Huang P.L., Panahian N., Dalkara T., Fishman M.C., Moskowitz M.A. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 265:1994;1883-1885.
    • (1994) Science , vol.265 , pp. 1883-1885
    • Huang, Z.1    Huang, P.L.2    Panahian, N.3    Dalkara, T.4    Fishman, M.C.5    Moskowitz, M.A.6
  • 11
    • 0027942138 scopus 로고
    • The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels
    • Yoshida T., Limmroth V., Irikura K., Moskowitz M.A. The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J. Cereb. Blood Flow Metab. 14:1994;924-929.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 924-929
    • Yoshida, T.1    Limmroth, V.2    Irikura, K.3    Moskowitz, M.A.4
  • 12
    • 0028851010 scopus 로고
    • Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion
    • Zhang Z.G., Chopp M., Bailey F., Malinski T. Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion. J. Neurolog. Sci. 128:1995;22-27.
    • (1995) J. Neurolog. Sci. , vol.128 , pp. 22-27
    • Zhang, Z.G.1    Chopp, M.2    Bailey, F.3    Malinski, T.4
  • 13
    • 0030664096 scopus 로고    scopus 로고
    • Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene
    • Iadecola C., Zhang F., Casey R., Nagayama M., Ross M.E. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J. Neurosci. 17:1997;9157-9164.
    • (1997) J. Neurosci. , vol.17 , pp. 9157-9164
    • Iadecola, C.1    Zhang, F.2    Casey, R.3    Nagayama, M.4    Ross, M.E.5
  • 14
    • 0029294575 scopus 로고
    • Inducible nitric oxide synthase gene expression in brain following cerebral ischemia
    • Iadecola C., Zhang F., Xu S., Casey R., Ross M.E. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J. Cereb. Blood Flow Metab. 15:1995;378-384.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 378-384
    • Iadecola, C.1    Zhang, F.2    Xu, S.3    Casey, R.4    Ross, M.E.5
  • 15
    • 0029670958 scopus 로고    scopus 로고
    • Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion
    • Zhang F., Casey R.M., Ross M.E., Iadecola C. Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke. 27:1996;317-323.
    • (1996) Stroke , vol.27 , pp. 317-323
    • Zhang, F.1    Casey, R.M.2    Ross, M.E.3    Iadecola, C.4
  • 18
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reducatse inhibitors mediated by endothelial nitric oxide synthase
    • Endres M., Caufs U., Huang Z., Nakamura T., Huang P., Moskowitz M.A., Liao J.K. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reducatse inhibitors mediated by endothelial nitric oxide synthase. Proc. Natl. Acad. Sci USA. 95:1998;8880-8885.
    • (1998) Proc. Natl. Acad. Sci USA , vol.95 , pp. 8880-8885
    • Endres, M.1    Caufs, U.2    Huang, Z.3    Nakamura, T.4    Huang, P.5    Moskowitz, M.A.6    Liao, J.K.7
  • 20
    • 0028978149 scopus 로고
    • N-nitro-l-arginine and N-monomethyl-l-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases
    • Reif D.W., McCreedy S.A. N-nitro-l-arginine and N-monomethyl-l-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases. Arch. Biochem. Biophys. 320:1995;170-176.
    • (1995) Arch. Biochem. Biophys. , vol.320 , pp. 170-176
    • Reif, D.W.1    McCreedy, S.A.2
  • 21
  • 23
    • 0029950863 scopus 로고    scopus 로고
    • Administration of a competitive NMDA antagonist MDL-100,453 reduces infarct size after permanent middle cerebral artery occlusion in rat
    • Jiang N., Zhang R.L., Baron B.M., Chopp M. Administration of a competitive NMDA antagonist MDL-100,453 reduces infarct size after permanent middle cerebral artery occlusion in rat. J. Neurolog. Sci. 138:1996;36-41.
    • (1996) J. Neurolog. Sci. , vol.138 , pp. 36-41
    • Jiang, N.1    Zhang, R.L.2    Baron, B.M.3    Chopp, M.4
  • 27
    • 0030878787 scopus 로고    scopus 로고
    • Synthesis, in vivo evaluation and PET study of carbon-11-labeled neuronal nitric oxide synthase (nNOS inhibitor) S-methyl-L-thiocitrulline
    • Zhang J., Xu M., Dence C., Sherman E.L.C., McCarthy T.J., Welch M.J. Synthesis, in vivo evaluation and PET study of carbon-11-labeled neuronal nitric oxide synthase (nNOS inhibitor) S-methyl-L-thiocitrulline. J. Nucl. Med. 38:1997;1273-1278.
    • (1997) J. Nucl. Med. , vol.38 , pp. 1273-1278
    • Zhang, J.1    Xu, M.2    Dence, C.3    Sherman, E.L.C.4    McCarthy, T.J.5    Welch, M.J.6
  • 30
    • 0032416666 scopus 로고    scopus 로고
    • Crystal structure of constitutive endothelial nitric oxide synthase: A paradigm for pterin function involving a novel metal center
    • Raman C.S., Li H., Martasek P., Kral V., Masters B.S., Poulos T.L. Crystal structure of constitutive endothelial nitric oxide synthase a paradigm for pterin function involving a novel metal center . Cell. 95:1998;939-950.
    • (1998) Cell , vol.95 , pp. 939-950
    • Raman, C.S.1    Li, H.2    Martasek, P.3    Kral, V.4    Masters, B.S.5    Poulos, T.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.