-
1
-
-
0029935269
-
Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability
-
Albakri QA and Stuehr DJ (1996) Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability. J Biol Chem 271:5414-5421.
-
(1996)
J Biol Chem
, vol.271
, pp. 5414-5421
-
-
Albakri, Q.A.1
Stuehr, D.J.2
-
2
-
-
0032524515
-
Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay
-
Alderton WK, Boyhan A, and Lowe PN (1998) Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay. Biochem J 332:195-201.
-
(1998)
Biochem J
, vol.332
, pp. 195-201
-
-
Alderton, W.K.1
Boyhan, A.2
Lowe, P.N.3
-
3
-
-
0032998811
-
Nitric oxide synthase and cyclooxygenases: Distribution, regulation and intervention in arthritis
-
Amin AR, Attur M, and Abramson SB (1999) Nitric oxide synthase and cyclooxygenases: distribution, regulation and intervention in arthritis. Curr Opin Rheumatol 11:202-209.
-
(1999)
Curr Opin Rheumatol
, vol.11
, pp. 202-209
-
-
Amin, A.R.1
Attur, M.2
Abramson, S.B.3
-
4
-
-
0034714237
-
Heme insertion, assembly and activation of apo-neuronal nitric-oxide synthase in vitro
-
Bender AT, Nakatsuka M, and Osawa Y (2000) Heme insertion, assembly and activation of apo-neuronal nitric-oxide synthase in vitro. J Biol Chem 275:26018-26023.
-
(2000)
J Biol Chem
, vol.275
, pp. 26018-26023
-
-
Bender, A.T.1
Nakatsuka, M.2
Osawa, Y.3
-
5
-
-
0037016750
-
Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors
-
Blasko E, Glaser CB, Devlin JJ, Xia W, Feldman RI, Polokoff MA, Phillips GB, Whitlow M, Auld DS, McMillan K, et al. (2002) Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors. J Biol Chem 277:295-302.
-
(2002)
J Biol Chem
, vol.277
, pp. 295-302
-
-
Blasko, E.1
Glaser, C.B.2
Devlin, J.J.3
Xia, W.4
Feldman, R.I.5
Polokoff, M.A.6
Phillips, G.B.7
Whitlow, M.8
Auld, D.S.9
McMillan, K.10
-
6
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
8
-
-
0033160868
-
Endothelial nitric oxide synthase expression and its functionality
-
Feron O (1999) Endothelial nitric oxide synthase expression and its functionality. Curr Opin Clin Nutr Metab Care 2:291-296.
-
(1999)
Curr Opin Clin Nutr Metab Care
, vol.2
, pp. 291-296
-
-
Feron, O.1
-
9
-
-
0034058372
-
Interaction of endothelial and neuronal nitric-oxide syntheses with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation
-
Golser R, Gorren ACF, Leber A, Andrew P, Habisch HJ, Werner ER, Schmidt K, Venema RC, and Mayer B (2000) Interaction of endothelial and neuronal nitric-oxide syntheses with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation. J Biol Chem 275: 5291-5296.
-
(2000)
J Biol Chem
, vol.275
, pp. 5291-5296
-
-
Golser, R.1
Gorren, A.C.F.2
Leber, A.3
Andrew, P.4
Habisch, H.J.5
Werner, E.R.6
Schmidt, K.7
Venema, R.C.8
Mayer, B.9
-
10
-
-
0030464496
-
Pteridine-free neuronal nitric oxide synthase: Evidence for two identical highly anticooperative tetrahydrobiopterin binding sites
-
Gorren ACF, List BM, Schrammel A, Pitters E, Hemmens B, Werner ER, Schmidt K, and Mayer B (1996) Pteridine-free neuronal nitric oxide synthase: evidence for two identical highly anticooperative tetrahydrobiopterin binding sites. Biochemistry 35:16735-16745.
-
(1996)
Biochemistry
, vol.35
, pp. 16735-16745
-
-
Gorren, A.C.F.1
List, B.M.2
Schrammel, A.3
Pitters, E.4
Hemmens, B.5
Werner, E.R.6
Schmidt, K.7
Mayer, B.8
-
11
-
-
0032113555
-
The versatile and complex enzymology of nitric oxide synthase
-
Gorren ACF and Mayer B (1998) The versatile and complex enzymology of nitric oxide synthase. Biochemistry (Moscow) 63:734-743.
-
(1998)
Biochemistry (Moscow)
, vol.63
, pp. 734-743
-
-
Gorren, A.C.F.1
Mayer, B.2
-
12
-
-
0028577804
-
Expression of rat brain nitric oxide synthase in baculovirus-infected insect cells and characterization of the purified enzyme
-
Harteneck C, Klatt P, Schmidt K, and Mayer B (1994) Expression of rat brain nitric oxide synthase in baculovirus-infected insect cells and characterization of the purified enzyme. Biochem J 304:683-686.
-
(1994)
Biochem J
, vol.304
, pp. 683-686
-
-
Harteneck, C.1
Klatt, P.2
Schmidt, K.3
Mayer, B.4
-
13
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, and Vogelstein B (1998) A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95: 2509-2514.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
14
-
-
0026584089
-
2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
-
2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 281:627-630.
-
(1992)
Biochem J
, vol.281
, pp. 627-630
-
-
Heinzel, B.1
John, M.2
Klatt, P.3
Böhme, E.4
Mayer, B.5
-
15
-
-
0032103447
-
Haem insertion, dimerization and reactivation of haem-free neuronal nitric oxide synthase
-
Hemmens B, Gorren ACF, Schmidt K, Werner ER, and Mayer B (1998) Haem insertion, dimerization and reactivation of haem-free neuronal nitric oxide synthase. Biochem J 332:337-342.
-
(1998)
Biochem J
, vol.332
, pp. 337-342
-
-
Hemmens, B.1
Gorren, A.C.F.2
Schmidt, K.3
Werner, E.R.4
Mayer, B.5
-
16
-
-
0035283321
-
Expression and function of inducible nitric oxide synthase in neurons
-
Heneka MT and Feinstein DL (2001) Expression and function of inducible nitric oxide synthase in neurons. J Neuroimmunol 114:8-18.
-
(2001)
J Neuroimmunol
, vol.114
, pp. 8-18
-
-
Heneka, M.T.1
Feinstein, D.L.2
-
17
-
-
0028302095
-
The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity and allosteric interaction with the substrate domain
-
Klatt P, Schmid M, Leopold E, Schmidt K, Werner ER, and Mayer B (1994) The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity and allosteric interaction with the substrate domain. J Biol Chem 269:13861-13866.
-
(1994)
J Biol Chem
, vol.269
, pp. 13861-13866
-
-
Klatt, P.1
Schmid, M.2
Leopold, E.3
Schmidt, K.4
Werner, E.R.5
Mayer, B.6
-
18
-
-
0029125762
-
Structural analysis of porcine brain nitric oxide synthase reveals novel role of tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer
-
Klatt P, Schmidt K, Lehner D, Glatter O, Bächinger HP, and Mayer B (1995) Structural analysis of porcine brain nitric oxide synthase reveals novel role of tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer. EMBO (Eur Mol Biol Organ) J 14:3687-3695.
-
(1995)
EMBO (Eur Mol Biol Organ) J
, vol.14
, pp. 3687-3695
-
-
Klatt, P.1
Schmidt, K.2
Lehner, D.3
Glatter, O.4
Bächinger, H.P.5
Mayer, B.6
-
19
-
-
0029819905
-
Determination of nitric oxide synthase cofartors: Heme, FAD, FMN and tetrahydrobiopterin
-
Klatt P, Schmidt K, Werner ER, and Mayer B (1996a) Determination of nitric oxide synthase cofartors: heme, FAD, FMN and tetrahydrobiopterin. Methods Enzymol 268:358-365.
-
(1996)
Methods Enzymol
, vol.268
, pp. 358-365
-
-
Klatt, P.1
Schmidt, K.2
Werner, E.R.3
Mayer, B.4
-
20
-
-
0029929385
-
Characterization of heme-deficient neuronal nitric oxide synthase reveals role for heme in subunit dimerization and binding of amino acid substrate and tetrahydrobiopterin
-
Klatt P, Pfeiffer S, List BM, Lehner D, Glatter O, Werner ER, Schmidt K, and Mayer B (1996b) Characterization of heme-deficient neuronal nitric oxide synthase reveals role for heme in subunit dimerization and binding of amino acid substrate and tetrahydrobiopterin. J Biol Chem 271:7336-7342.
-
(1996)
J Biol Chem
, vol.271
, pp. 7336-7342
-
-
Klatt, P.1
Pfeiffer, S.2
List, B.M.3
Lehner, D.4
Glatter, O.5
Werner, E.R.6
Schmidt, K.7
Mayer, B.8
-
21
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond) 227:680-685.
-
(1970)
Nature (Lond)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
22
-
-
0029913323
-
Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of heme for tetrahydrobiopterin binding
-
List BM, Klatt P, Werner ER, Schmidt K, and Mayer B (1996) Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of heme for tetrahydrobiopterin binding. Biochem J 315:57-63.
-
(1996)
Biochem J
, vol.315
, pp. 57-63
-
-
List, B.M.1
Klatt, P.2
Werner, E.R.3
Schmidt, K.4
Mayer, B.5
-
23
-
-
0031844699
-
Nitric oxide synthases: Catalytic function and progress towards selective inhibition
-
Mayer B and Andrew P (1998) Nitric oxide synthases: catalytic function and progress towards selective inhibition. Naunyn-Schmiedeberg's Arch Pharmacol 358:127-133
-
(1998)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.358
, pp. 127-133
-
-
Mayer, B.1
Andrew, P.2
-
24
-
-
0030694038
-
Biosynthesis and action of nitric oxide in mammalian cells
-
Mayer B and Hemmens B (1997) Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 22:477-481.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 477-481
-
-
Mayer, B.1
Hemmens, B.2
-
25
-
-
0029843621
-
Large scale purification of rat brain nitric oxide synthase from a baculovirus overexpression system
-
Mayer B, List BM, Klatt P, Harteneck C, and Schmidt K (1996) Large scale purification of rat brain nitric oxide synthase from a baculovirus overexpression system. Methods Enzymol 268:420-427.
-
(1996)
Methods Enzymol
, vol.268
, pp. 420-427
-
-
Mayer, B.1
List, B.M.2
Klatt, P.3
Harteneck, C.4
Schmidt, K.5
-
26
-
-
2142754958
-
Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry
-
McMillan K, Adler M, Auld DS, Baldwin JJ, Blasko E, Browne LJ, Chelsky D, Davey D, Dolle RE, Eagen KA, et al. (2000) Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry. Proc Natl Acad Sci USA 97:1506-1511.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1506-1511
-
-
McMillan, K.1
Adler, M.2
Auld, D.S.3
Baldwin, J.J.4
Blasko, E.5
Browne, L.J.6
Chelsky, D.7
Davey, D.8
Dolle, R.E.9
Eagen, K.A.10
-
27
-
-
0028863627
-
Molecular mechanisms and therapeutic strategies related to nitric oxide
-
Moncada S and Higgs EA (1995) Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J 9:1319-1330.
-
(1995)
FASEB J
, vol.9
, pp. 1319-1330
-
-
Moncada, S.1
Higgs, E.A.2
-
28
-
-
0034723394
-
Guanabenz-mediated inactivation and enhanced proteolytic degradation of neuronal nitric-oxide synthase
-
Noguchi S, Jianmongkol S, Bender AT, Kamada Y, Demady DR, and Osawa Y (2000) Guanabenz-mediated inactivation and enhanced proteolytic degradation of neuronal nitric-oxide synthase. J Biol Chem 275:2376-2380.
-
(2000)
J Biol Chem
, vol.275
, pp. 2376-2380
-
-
Noguchi, S.1
Jianmongkol, S.2
Bender, A.T.3
Kamada, Y.4
Demady, D.R.5
Osawa, Y.6
-
29
-
-
0015216932
-
The mechanism by which cycloheximide and related glutarimide antibiotics inhibit peptide synthesis on reticulocyte ribosomes
-
Obrig TG, Culp WJ, McKeehan WL, and Hardesty B (1971) The mechanism by which cycloheximide and related glutarimide antibiotics inhibit peptide synthesis on reticulocyte ribosomes. J Biol Chem 246:174-181.
-
(1971)
J Biol Chem
, vol.246
, pp. 174-181
-
-
Obrig, T.G.1
Culp, W.J.2
McKeehan, W.L.3
Hardesty, B.4
-
30
-
-
0037163086
-
Distinct dimer interaction and regulation in nitric-oxide synthase types I, II and III
-
Panda K, Rosenfeld RJ, Ghosh S, Meade AL, Getzoff ED, and Stuehr DJ (2002) Distinct dimer interaction and regulation in nitric-oxide synthase types I, II and III. J Biol Chem 277:31020-31030.
-
(2002)
J Biol Chem
, vol.277
, pp. 31020-31030
-
-
Panda, K.1
Rosenfeld, R.J.2
Ghosh, S.3
Meade, A.L.4
Getzoff, E.D.5
Stuehr, D.J.6
-
31
-
-
0033553802
-
Nitric oxide: Chemical puzzles posed by a biological messenger
-
Pfeiffer S, Mayer B, and Hemmens B (1999) Nitric oxide: chemical puzzles posed by a biological messenger. Angew Chem Int Edit 38:1715-1731.
-
(1999)
Angew Chem Int Edit
, vol.38
, pp. 1715-1731
-
-
Pfeiffer, S.1
Mayer, B.2
Hemmens, B.3
-
32
-
-
0026470180
-
Generation of superoxide by purified brain nitric oxide synthase
-
Pou S, Pou WS, Bredt DS, Snyder SH, and Rosen GM (1992) Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem 267:24173-24176.
-
(1992)
J Biol Chem
, vol.267
, pp. 24173-24176
-
-
Pou, S.1
Pou, W.S.2
Bredt, D.S.3
Snyder, S.H.4
Rosen, G.M.5
-
33
-
-
0035200017
-
Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells
-
Schmidt K, Andrew P, Schrammel A, Groschner K, Schmitz V, Kojda G, and Mayer B (2001) Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells. Am J Physiol 281:H2053-H2061.
-
(2001)
Am J Physiol
, vol.281
-
-
Schmidt, K.1
Andrew, P.2
Schrammel, A.3
Groschner, K.4
Schmitz, V.5
Kojda, G.6
Mayer, B.7
-
34
-
-
0001787956
-
Assay of tissue activity of nitric oxide synthase
-
Maines M, Costa L, Reed D, and Sassa S eds, John Wiley & Sons, Inc., New York
-
Schmidt K and Mayer B (1999) Assay of tissue activity of nitric oxide synthase, in Current Protocols in Toxicology (Maines M, Costa L, Reed D, and Sassa S eds) pp 10.2.1-10.2.13, John Wiley & Sons, Inc., New York.
-
(1999)
Current Protocols in Toxicology
, pp. 1021-10213
-
-
Schmidt, K.1
Mayer, B.2
-
35
-
-
0024347031
-
Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells
-
Schmidt K, Mayer B, and Kukovetz WR (1989) Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells. Eur J Pharmacol 170:157-166.
-
(1989)
Eur J Pharmacol
, vol.170
, pp. 157-166
-
-
Schmidt, K.1
Mayer, B.2
Kukovetz, W.R.3
-
36
-
-
0033534474
-
Antifungal imidazoles block assembly of inducible NO synthase into an active dimer
-
Sennequier N, Wolan D, and Stuehr DJ (1999) Antifungal imidazoles block assembly of inducible NO synthase into an active dimer. J Biol Chem 274:930-938.
-
(1999)
J Biol Chem
, vol.274
, pp. 930-938
-
-
Sennequier, N.1
Wolan, D.2
Stuehr, D.J.3
-
37
-
-
0032563106
-
Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer
-
Siddhanta U, Presta A, Fan BC, Wolan D, Rousseau DL, and Stuehr DJ (1998) Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer. J Biol Chem 273:18950-18958.
-
(1998)
J Biol Chem
, vol.273
, pp. 18950-18958
-
-
Siddhanta, U.1
Presta, A.2
Fan, B.C.3
Wolan, D.4
Rousseau, D.L.5
Stuehr, D.J.6
-
39
-
-
0031002421
-
Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
-
Xia Y and Zweier JL (1997) Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proc Natl Acad Sci USA 94:6954-6958.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6954-6958
-
-
Xia, Y.1
Zweier, J.L.2
-
40
-
-
0035903238
-
Nitric oxide synthase (NOS2) mutation in Dahl/Rapp rats decreases enzyme stability
-
Ying WZ, Xia H, and Sanders PW (2001) Nitric oxide synthase (NOS2) mutation in Dahl/Rapp rats decreases enzyme stability. Circ Res 89:317-322.
-
(2001)
Circ Res
, vol.89
, pp. 317-322
-
-
Ying, W.Z.1
Xia, H.2
Sanders, P.W.3
|