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Biochemistry

Volumn 40, Issue 45, 2001, Pages 13448-13455

Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism

(6) Raman, C S a Li, H a Martasek P b,c Southan, G d Masters, B S S b Poulos, T L a

a UNIVERSITY OF CALIFORNIA (United States)

b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO (United States)

c CHARLES UNIVERSITY (Czech Republic)

d INOTEK CORPORATION (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGANDS;

CONFORMATIONS; CRYSTAL STRUCTURE; DISEASES; ENZYMES; SUBSTRATES;

BIOCHEMISTRY;

3 BROMO 7 NITROINDAZOLE; INDAZOLE DERIVATIVE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRO DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; ENZYME INACTIVATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; MOLECULAR MODEL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

BINDING SITES; BIOPTERIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENZYME INHIBITORS; INDAZOLES; MODELS, MOLECULAR; NITRIC OXIDE SYNTHASE; NITROARGININE; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 0035856516 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi010957u Document Type: Article

Times cited : (84)

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