-
2
-
-
0025613812
-
Linkage of early-onset familial breast cancer to chromosome 17q21
-
Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 1990; 250:1684-9.
-
(1990)
Science
, vol.250
, pp. 1684-1689
-
-
Hall, J.M.1
Lee, M.K.2
Newman, B.3
Morrow, J.E.4
Anderson, L.A.5
Huey, B.6
-
3
-
-
0026935108
-
Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome
-
Smith SA, Easton DF, Evans DG, Ponder BA. Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nat Genet 1992; 2:128-31.
-
(1992)
Nat Genet
, vol.2
, pp. 128-131
-
-
Smith, S.A.1
Easton, D.F.2
Evans, D.G.3
Ponder, B.A.4
-
4
-
-
0027960790
-
Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds
-
Neuhausen SL, Marshall CJ. Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds. Cancer Res 1994; 54:6069-72.
-
(1994)
Cancer Res
, vol.54
, pp. 6069-6072
-
-
Neuhausen, S.L.1
Marshall, C.J.2
-
5
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
USA
-
Knudson Jr AG. Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 1971; 68:820-3.
-
(1971)
Proc Natl Acad Sci
, vol.68
, pp. 820-823
-
-
Knudson Jr., A.G.1
-
6
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
-
7
-
-
0028073794
-
BRCA1 mutations in primary breast and ovarian carcinomas
-
Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S et al. BRCA1 mutations in primary breast and ovarian carcinomas. Science 1994; 266:120-2.
-
(1994)
Science
, vol.266
, pp. 120-122
-
-
Futreal, P.A.1
Liu, Q.2
Shattuck-Eidens, D.3
Cochran, C.4
Harshman, K.5
Tavtigian, S.6
-
9
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995; 378:789-92.
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
Mangion, J.6
-
10
-
-
0029919109
-
Hereditary cancer: Two hits revisited
-
Knudson AG. Hereditary cancer: Two hits revisited. J Cancer Res Clin Oncol 1996; 122:135-40.
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 135-140
-
-
Knudson, A.G.1
-
11
-
-
9044225148
-
BRCA2 mutations in primary breast and ovarian cancers
-
Lancaster JM, Wooster R, Mangion J, Phelan CM, Cochran C, Gumbs C et al. BRCA2 mutations in primary breast and ovarian cancers. Nat Genet 1996; 13:238-40.
-
(1996)
Nat Genet
, vol.13
, pp. 238-240
-
-
Lancaster, J.M.1
Wooster, R.2
Mangion, J.3
Phelan, C.M.4
Cochran, C.5
Gumbs, C.6
-
12
-
-
0030843274
-
Methylation of the BRCA1 gene in sporadic breast cancer
-
Dobrovic A, Simpfendorfer D. Methylation of the BRCA1 gene in sporadic breast cancer. Cancer Res 1997; 57:3347-50.
-
(1997)
Cancer Res
, vol.57
, pp. 3347-3350
-
-
Dobrovic, A.1
Simpfendorfer, D.2
-
13
-
-
0032497635
-
Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells
-
Rice JC, Massey-Brown KS, Futscher BW. Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells. Oncogene 1998; 17:1807-12.
-
(1998)
Oncogene
, vol.17
, pp. 1807-1812
-
-
Rice, J.C.1
Massey-Brown, K.S.2
Futscher, B.W.3
-
14
-
-
0032542339
-
Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region
-
Magdinier F, Ribieras S, Lenoir GM, Frappart L, Dante R. Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region. Oncogene 1998; 17:3169-76.
-
(1998)
Oncogene
, vol.17
, pp. 3169-3176
-
-
Magdinier, F.1
Ribieras, S.2
Lenoir, G.M.3
Frappart, L.4
Dante, R.5
-
16
-
-
0023712476
-
The RAD9 gene controls the cell cycle response to DNA damage in saccharomyces cerevisiae
-
Weinert TA, Hartwell LH. The RAD9 gene controls the cell cycle response to DNA damage in saccharomyces cerevisiae. Science 1988; 241:317-22.
-
(1988)
Science
, vol.241
, pp. 317-322
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
17
-
-
0031046294
-
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
-
Bork P, Hofmann K, Bucher P, Neuwald AF, Altschul SF, Koonin EV. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB Journal 1997; 11:68-76.
-
(1997)
FASEB Journal
, vol.11
, pp. 68-76
-
-
Bork, P.1
Hofmann, K.2
Bucher, P.3
Neuwald, A.F.4
Altschul, S.F.5
Koonin, E.V.6
-
18
-
-
0031031787
-
From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair
-
Callebaut I, Mornon JP. From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair. FEBS Letters 1997; 400:25-30.
-
(1997)
FEBS Letters
, vol.400
, pp. 25-30
-
-
Callebaut, I.1
Mornon, J.P.2
-
19
-
-
0036906303
-
Checkpoint signalling: Focusing on 53BP1
-
Abraham RT. Checkpoint signalling: Focusing on 53BP1. Nat Cell Biol 2002; 4:E277-9.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Abraham, R.T.1
-
20
-
-
0029830051
-
Transcriptional activation by BRCA1
-
Chapman MS, Verma IM. Transcriptional activation by BRCA1. Nature 1996; 382:678-9.
-
(1996)
Nature
, vol.382
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
21
-
-
0030474170
-
Evidence for a transcriptional activation function of BRCA1 C-terminal region
-
USA
-
Monteiro AN, August A, Hanafusa H. Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci USA 1996; 93:13595-9.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 13595-13599
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
22
-
-
0030965157
-
BRCA1 is a component of the RNA polymerase II holoenzyme
-
USA
-
Scully R, Anderson SF, Chao DM, Wei W, Ye L, Young RA, et al. BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci USA 1997; 94:5605-10.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 5605-5610
-
-
Scully, R.1
Anderson, S.F.2
Chao, D.M.3
Wei, W.4
Ye, L.5
Young, R.A.6
-
24
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu X, Wu LC, Bowcock AM, Aronheim A, Baer R. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J Biol Chem 1998; 273:25388-92.
-
(1998)
J Biol Chem
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
25
-
-
0035842893
-
BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
-
Ye Q, Hu YF, Zhong H, Nye AC, Belmont AS, Li R. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol 2001; 155:911-21.
-
(2001)
J Cell Biol
, vol.155
, pp. 911-921
-
-
Ye, Q.1
Hu, Y.F.2
Zhong, H.3
Nye, A.C.4
Belmont, A.S.5
Li, R.6
-
26
-
-
20644461718
-
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
-
Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, et al. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell 2001; 105:149-60.
-
(2001)
Cell
, vol.105
, pp. 149-160
-
-
Cantor, S.B.1
Bell, D.W.2
Ganesan, S.3
Kass, E.M.4
Drapkin, R.5
Grossman, S.6
-
27
-
-
2342618304
-
The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations
-
USA
-
Cantor S, Drapkin R, Zhang F, Lin Y, Han J, Pamidi S, et al. The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. Proc Natl Acad Sci USA 2004; 101:2357-62.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 2357-2362
-
-
Cantor, S.1
Drapkin, R.2
Zhang, F.3
Lin, Y.4
Han, J.5
Pamidi, S.6
-
28
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science 2003; 302:639-42.
-
(2003)
Science
, vol.302
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
29
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
Manke IA, Lowery DM, Nguyen A, Yaffe MB. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 2003; 302:636-9.
-
(2003)
Science
, vol.302
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
30
-
-
2542490186
-
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
-
Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol 2004; 11:519-25.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 519-525
-
-
Williams, R.S.1
Lee, M.S.2
Hau, D.D.3
Glover, J.N.4
-
31
-
-
0025856958
-
Colinearity of novel genes in the class II regions of the MHC in mouse and human
-
Hanson IM, Trowsdale J. Colinearity of novel genes in the class II regions of the MHC in mouse and human. Immunogenetics 1991; 34:5-11.
-
(1991)
Immunogenetics
, vol.34
, pp. 5-11
-
-
Hanson, I.M.1
Trowsdale, J.2
-
32
-
-
0028181750
-
Structure of the C3HC4 domain by 1H-nuclear magnetic resonance spectroscopy. A new structural class of zinc-finger
-
Barlow PN, Luisi B, Milner A, Elliott M, Everett R. Structure of the C3HC4 domain by 1H-nuclear magnetic resonance spectroscopy. A new structural class of zinc-finger. J Mol Biol 1994; 237:201-11.
-
(1994)
J Mol Biol
, vol.237
, pp. 201-211
-
-
Barlow, P.N.1
Luisi, B.2
Milner, A.3
Elliott, M.4
Everett, R.5
-
33
-
-
0034804672
-
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
-
Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol 2001; 8:833-7.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 833-837
-
-
Brzovic, P.S.1
Rajagopal, P.2
Hoyt, D.W.3
King, M.C.4
Klevit, R.E.5
-
34
-
-
10544231876
-
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
-
Wu LC, Wang ZW, Tsan JT, Spillman MA, Phung A, Xu XL, et al. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nature Genetics 1996; 14:430-40.
-
(1996)
Nature Genetics
, vol.14
, pp. 430-440
-
-
Wu, L.C.1
Wang, Z.W.2
Tsan, J.T.3
Spillman, M.A.4
Phung, A.5
Xu, X.L.6
-
35
-
-
0035833994
-
Functional communication between endogenous BRCA1 and its partner, BARD1, during xenopus laevis development
-
USA
-
Joukov V, Chen J, Fox EA, Green JB, Livingston DM. Functional communication between endogenous BRCA1 and its partner, BARD1, during xenopus laevis development. Proc Natl Acad Sci USA 2001; 98:12078-83.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 12078-12083
-
-
Joukov, V.1
Chen, J.2
Fox, E.A.3
Green, J.B.4
Livingston, D.M.5
-
36
-
-
0033613222
-
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
-
USA
-
Lorick KL, Jensen JP, Fang S, Ong AM, Hatakeyama S, Weissman AM. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc Natl Acad Sci USA 1999; 96:11364-9.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 11364-11369
-
-
Lorick, K.L.1
Jensen, J.P.2
Fang, S.3
Ong, A.M.4
Hatakeyama, S.5
Weissman, A.M.6
-
37
-
-
0035942190
-
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
-
USA
-
Ruffner H, Joazeiro CA, Hemmati D, Hunter T, Verma IM. Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci USA 2001; 98:5134-9.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 5134-5139
-
-
Ruffner, H.1
Joazeiro, C.A.2
Hemmati, D.3
Hunter, T.4
Verma, I.M.5
-
38
-
-
0035805582
-
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
-
Hashizume R, Fukuda M, Maeda I, Nishikawa H, Oyake D, Yabuki Y, et al. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem 2001; 276:14537-40.
-
(2001)
J Biol Chem
, vol.276
, pp. 14537-14540
-
-
Hashizume, R.1
Fukuda, M.2
Maeda, I.3
Nishikawa, H.4
Oyake, D.5
Yabuki, Y.6
-
39
-
-
0038237514
-
Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein
-
Xia Y, Pao GM, Chen HW, Verma IM, Hunter T. Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein. J Biol Chem 2003; 278:5255-63.
-
(2003)
J Biol Chem
, vol.278
, pp. 5255-5263
-
-
Xia, Y.1
Pao, G.M.2
Chen, H.W.3
Verma, I.M.4
Hunter, T.5
-
40
-
-
0042317328
-
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin
-
Wu-Baer F, Lagrazon K, Yuan W, Baer R. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin. J Biol Chem 2003; 278:34743-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 34743-34746
-
-
Wu-Baer, F.1
Lagrazon, K.2
Yuan, W.3
Baer, R.4
-
41
-
-
1042278177
-
Mass spectrometric and mutational analyses reveal lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase
-
Nishikawa H, Ooka S, Sato K, Arima K, Okamoto J, Klevit RE, et al. Mass spectrometric and mutational analyses reveal lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase. J Biol Chem 2004; 279:3916-24.
-
(2004)
J Biol Chem
, vol.279
, pp. 3916-3924
-
-
Nishikawa, H.1
Ooka, S.2
Sato, K.3
Arima, K.4
Okamoto, J.5
Klevit, R.E.6
-
42
-
-
1842364973
-
Localization of BRCA1 and a splice variant identifies the nuclear localization signal
-
Thakur S, Zhang HB, Peng Y, Le H, Carroll B, Ward T, et al. Localization of BRCA1 and a splice variant identifies the nuclear localization signal. Molecular & Cellular Biology 1997; 17:444-52.
-
(1997)
Molecular & Cellular Biology
, vol.17
, pp. 444-452
-
-
Thakur, S.1
Zhang, H.B.2
Peng, Y.3
Le, H.4
Carroll, B.5
Ward, T.6
-
43
-
-
0035018530
-
Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci
-
Huber LJ, Yang TW, Sarkisian CJ, Master SR, Deng CX, Chodosh LA. Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci. Mol Cell Biol 2001; 21:4005-15.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4005-4015
-
-
Huber, L.J.1
Yang, T.W.2
Sarkisian, C.J.3
Master, S.R.4
Deng, C.X.5
Chodosh, L.A.6
-
44
-
-
0032587877
-
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
-
Xu X, Wagner KU, Larson D, Weaver Z, Li C, Ried T, et al. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat Genet 1999; 22:37-43.
-
(1999)
Nat Genet
, vol.22
, pp. 37-43
-
-
Xu, X.1
Wagner, K.U.2
Larson, D.3
Weaver, Z.4
Li, C.5
Ried, T.6
-
45
-
-
0035932978
-
Direct DNA binding by Brca1
-
USA
-
Paull TT, Cortez D, Bowers B, Elledge SJ, Gellert M. Direct DNA binding by Brca1. Proc Natl Acad Sci USA 2001; 98:6086-91.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 6086-6091
-
-
Paull, T.T.1
Cortez, D.2
Bowers, B.3
Elledge, S.J.4
Gellert, M.5
-
46
-
-
0031472370
-
Association of BRCA1 with Rad51 in mitotic and meiotic cells
-
Scully R, Chen J, Plug A, Xiao Y, Weaver D, Feunteun J, et al. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 1997; 88:265-75.
-
(1997)
Cell
, vol.88
, pp. 265-275
-
-
Scully, R.1
Chen, J.2
Plug, A.3
Xiao, Y.4
Weaver, D.5
Feunteun, J.6
-
47
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 1997; 90:425-35.
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
Keegan, K.4
Hoekstra, M.5
Feunteun, J.6
-
48
-
-
0030839860
-
Induction of phosphorylation on BRCA1 during the cell cycle and after DNA damage
-
Thomas JE, Smith M, Tonkinson JL, Rubinfeld B, Polakis P. Induction of phosphorylation on BRCA1 during the cell cycle and after DNA damage. Cell Growth Differ 1997; 8:801-9.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 801-809
-
-
Thomas, J.E.1
Smith, M.2
Tonkinson, J.L.3
Rubinfeld, B.4
Polakis, P.5
-
49
-
-
0029845485
-
Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells
-
Gudas JM, Li T, Nguyen H, Jensen D, Rauscher Jr F, Cowan KH. Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells. Cell Growth Differ 1996; 7:717-23.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 717-723
-
-
Gudas, J.M.1
Li, T.2
Nguyen, H.3
Jensen, D.4
Rauscher Jr., F.5
Cowan, K.H.6
-
50
-
-
10244246652
-
BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells
-
Vaughn JP, Davis PL, Jarboe MD, Huper G, Evans AC, Wiseman RW, et al. BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. Cell Growth Differ 1996; 7:711-5.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 711-715
-
-
Vaughn, J.P.1
Davis, P.L.2
Jarboe, M.D.3
Huper, G.4
Evans, A.C.5
Wiseman, R.W.6
-
51
-
-
0029115660
-
The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues
-
Marquis ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin GY, Abel KJ, et al. The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. Nat Genet 1995; 11:17-26.
-
(1995)
Nat Genet
, vol.11
, pp. 17-26
-
-
Marquis, S.T.1
Rajan, J.V.2
Wynshaw-Boris, A.3
Xu, J.4
Yin, G.Y.5
Abel, K.J.6
-
52
-
-
0032999336
-
BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site
-
Ruffner H, Jiang W, Craig AG, Hunter T, Verma IM. BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site. Mol Cell Biol 1999; 19:4843-54.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4843-4854
-
-
Ruffner, H.1
Jiang, W.2
Craig, A.G.3
Hunter, T.4
Verma, I.M.5
-
53
-
-
0027978039
-
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein
-
Sung P. Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein. Science 1994; 265:1241-3.
-
(1994)
Science
, vol.265
, pp. 1241-1243
-
-
Sung, P.1
-
54
-
-
0030584084
-
Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
-
Baumann P, Benson FE, West SC. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 1996; 87:757-66.
-
(1996)
Cell
, vol.87
, pp. 757-766
-
-
Baumann, P.1
Benson, F.E.2
West, S.C.3
-
55
-
-
0029775620
-
Meiosis: How could it work?
-
USA
-
Kleckner N. Meiosis: How could it work? Proc Natl Acad Sci USA 1996; 93:8167-74.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 8167-8174
-
-
Kleckner, N.1
-
56
-
-
0030933762
-
Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
-
Sharan SK, Morimatsu M, Albrecht U, Lim DS, Regel E, Dinh C, et al. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature 1997; 386:804-10.
-
(1997)
Nature
, vol.386
, pp. 804-810
-
-
Sharan, S.K.1
Morimatsu, M.2
Albrecht, U.3
Lim, D.S.4
Regel, E.5
Dinh, C.6
-
57
-
-
0031466027
-
RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2
-
Wong AK, Pero R, Ormonde PA, Tavtigian SV, Bartel PL. RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2. J Biol Chem 1997; 272:31941-4.
-
(1997)
J Biol Chem
, vol.272
, pp. 31941-31944
-
-
Wong, A.K.1
Pero, R.2
Ormonde, P.A.3
Tavtigian, S.V.4
Bartel, P.L.5
-
58
-
-
0035105999
-
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein
-
Davies AA, Masson JY, McIlwraith MJ, Stasiak AZ, Stasiak A, Venkitaraman AR, et al. Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol Cell 2001; 7:273-82.
-
(2001)
Mol Cell
, vol.7
, pp. 273-282
-
-
Davies, A.A.1
Masson, J.Y.2
McIlwraith, M.J.3
Stasiak, A.Z.4
Stasiak, A.5
Venkitaraman, A.R.6
-
59
-
-
2242443513
-
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
-
Pellegrini L, Yu DS, Lo T, Anand S, Lee M, Blundell TL, et al. Insights into DNA recombination from the structure of a RAD51-BRCA2 complex. Nature 2002; 420:287-93.
-
(2002)
Nature
, vol.420
, pp. 287-293
-
-
Pellegrini, L.1
Yu, D.S.2
Lo, T.3
Anand, S.4
Lee, M.5
Blundell, T.L.6
-
60
-
-
0032159062
-
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
-
Chen J, Silver DP, Walpita D, Cantor SB, Gazdar AF, Tomlinson G, et al. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell 1998; 2:317-28.
-
(1998)
Mol Cell
, vol.2
, pp. 317-328
-
-
Chen, J.1
Silver, D.P.2
Walpita, D.3
Cantor, S.B.4
Gazdar, A.F.5
Tomlinson, G.6
-
61
-
-
0345276495
-
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair
-
Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, et al. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Mol Cell 2003; 12:1087-99.
-
(2003)
Mol Cell
, vol.12
, pp. 1087-1099
-
-
Dong, Y.1
Hakimi, M.A.2
Chen, X.3
Kumaraswamy, E.4
Cooch, N.S.5
Godwin, A.K.6
-
62
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
-
Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science 1999; 286:1162-6.
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
63
-
-
0033637170
-
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
-
Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston DM, Elledge SJ et al. Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev 2000; 14:2989-3002.
-
(2000)
Genes Dev
, vol.14
, pp. 2989-3002
-
-
Tibbetts, R.S.1
Cortez, D.2
Brumbaugh, K.M.3
Scully, R.4
Livingston, D.M.5
Elledge, S.J.6
-
64
-
-
0015527017
-
Postreplicational repair of DNA in ultraviolet-irradiated mammalian cells
-
Lehmann AR. Postreplicational repair of DNA in ultraviolet-irradiated mammalian cells. J Mol Biol 1972; 66:319-37.
-
(1972)
J Mol Biol
, vol.66
, pp. 319-337
-
-
Lehmann, A.R.1
-
65
-
-
0018950869
-
Replication of ultraviolet-irradiated simian virus 40 in monkey kidney cells
-
Sarasin AR, Hanawalt PC. Replication of ultraviolet-irradiated simian virus 40 in monkey kidney cells. J Mol Biol 1980; 138:299-319.
-
(1980)
J Mol Biol
, vol.138
, pp. 299-319
-
-
Sarasin, A.R.1
Hanawalt, P.C.2
-
66
-
-
0013984737
-
DNA repair and genetic recombination: Studies on mutants of Escherichia coli defective in these processes
-
Howard-Flanders P, Boyce RP. DNA repair and genetic recombination: Studies on mutants of Escherichia coli defective in these processes. Radiat Res 1966; 6:156-84.
-
(1966)
Radiat Res
, vol.6
, pp. 156-184
-
-
Howard-Flanders, P.1
Boyce, R.P.2
-
67
-
-
0035902608
-
Rescue of arrested replication forks by homologous recombination
-
USA
-
Michel B, Flores MJ, Viguera E, Grompone G, Seigneur M, Bidnenko V. Rescue of arrested replication forks by homologous recombination. Proc Natl Acad Sci USA 2001; 98:8181-8.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 8181-8188
-
-
Michel, B.1
Flores, M.J.2
Viguera, E.3
Grompone, G.4
Seigneur, M.5
Bidnenko, V.6
-
68
-
-
0034026997
-
Replication and recombination intersect
-
Marians KJ. Replication and recombination intersect. Curr Opin Genet Dev 2000; 10:151-6.
-
(2000)
Curr Opin Genet Dev
, vol.10
, pp. 151-156
-
-
Marians, K.J.1
-
69
-
-
0034595010
-
The importance of repairing stalled replication forks
-
Cox MM, Goodman MF, Kreuzer KN, Sherratt DJ, Sandler SJ, Marians KJ. The importance of repairing stalled replication forks. Nature 2000; 404:37-41.
-
(2000)
Nature
, vol.404
, pp. 37-41
-
-
Cox, M.M.1
Goodman, M.F.2
Kreuzer, K.N.3
Sherratt, D.J.4
Sandler, S.J.5
Marians, K.J.6
-
70
-
-
0034177982
-
Links between replication, recombination and genome instability in eukaryotes
-
Flores-Rozas H, Kolodner RD. Links between replication, recombination and genome instability in eukaryotes. Trends Biochem Sci 2000; 25:196-200.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 196-200
-
-
Flores-Rozas, H.1
Kolodner, R.D.2
-
71
-
-
0031886721
-
The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis
-
Merrill BJ, Holm C. The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis. Genetics 1998; 148:611-24.
-
(1998)
Genetics
, vol.148
, pp. 611-624
-
-
Merrill, B.J.1
Holm, C.2
-
72
-
-
0029827367
-
The schizosaccharomyces pombe rad3 checkpoint gene
-
Bentley NJ, Holtzman DA, Flaggs G, Keegan KS, DeMaggio A, Ford JC, et al. The schizosaccharomyces pombe rad3 checkpoint gene. EMBO J 1996; 15:6641-51.
-
(1996)
EMBO J
, vol.15
, pp. 6641-6651
-
-
Bentley, N.J.1
Holtzman, D.A.2
Flaggs, G.3
Keegan, K.S.4
DeMaggio, A.5
Ford, J.C.6
-
73
-
-
0028353634
-
Mitotic check point genes in budding yeast and the dependence of mitosis on DNA replication and repair
-
Weinert TA, Kiser GL, Hartwell LH. Mitotic check point genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 1994; 8:652-65.
-
(1994)
Genes Dev
, vol.8
, pp. 652-665
-
-
Weinert, T.A.1
Kiser, G.L.2
Hartwell, L.H.3
-
74
-
-
0029085781
-
A checkpoint regulates the rate of progression through S phase in S. Cerevisiae in response to DNA damage
-
Paulovich AG, Hartwell LH. A checkpoint regulates the rate of progression through S phase in S. Cerevisiae in response to DNA damage. Cell 1995; 82:841-7.
-
(1995)
Cell
, vol.82
, pp. 841-847
-
-
Paulovich, A.G.1
Hartwell, L.H.2
-
75
-
-
0032497529
-
A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication
-
Santocanale C, Diffley JF. A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication. Nature 1998; 395:615-8.
-
(1998)
Nature
, vol.395
, pp. 615-618
-
-
Santocanale, C.1
Diffley, J.F.2
-
76
-
-
0035797383
-
The DNA replication checkpoint response stabilizes stalled replication forks
-
Lopes M, Cotta-Ramusino C, Pellicioli A, Liberi G, Plevani P, Muzi-Falconi M, et al. The DNA replication checkpoint response stabilizes stalled replication forks. Nature 2001; 412:557-61.
-
(2001)
Nature
, vol.412
, pp. 557-561
-
-
Lopes, M.1
Cotta-Ramusino, C.2
Pellicioli, A.3
Liberi, G.4
Plevani, P.5
Muzi-Falconi, M.6
-
77
-
-
0037178740
-
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
-
Sogo JM, Lopes M, Foiani M. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 2002; 297:599-602.
-
(2002)
Science
, vol.297
, pp. 599-602
-
-
Sogo, J.M.1
Lopes, M.2
Foiani, M.3
-
78
-
-
0035797444
-
Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
-
Tercero JA, Diffley JF. Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature 2001; 412:553-7.
-
(2001)
Nature
, vol.412
, pp. 553-557
-
-
Tercero, J.A.1
Diffley, J.F.2
-
79
-
-
0037178723
-
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
-
Cha RS, Kleckner N. ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 2002; 297:602-6.
-
(2002)
Science
, vol.297
, pp. 602-606
-
-
Cha, R.S.1
Kleckner, N.2
-
80
-
-
0035830498
-
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in saccharomyces cerevisiae
-
Myung K, Datta A, Kolodner RD. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in saccharomyces cerevisiae. Cell 2001; 104:397-408.
-
(2001)
Cell
, vol.104
, pp. 397-408
-
-
Myung, K.1
Datta, A.2
Kolodner, R.D.3
-
82
-
-
0346095320
-
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair
-
Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, et al. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair. Mol Cell Biol 2004; 24:708-18.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 708-718
-
-
Zhang, J.1
Willers, H.2
Feng, Z.3
Ghosh, J.C.4
Kim, S.5
Weaver, D.T.6
-
83
-
-
15844371372
-
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
-
Hakem R, de la Pompa JL, Sirard C, Mo R, Woo M, Hakem A, et al. The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell 1996; 85:1009-23.
-
(1996)
Cell
, vol.85
, pp. 1009-1023
-
-
Hakem, R.1
De La Pompa, J.L.2
Sirard, C.3
Mo, R.4
Woo, M.5
Hakem, A.6
-
84
-
-
0030924656
-
Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
-
Ludwig T, Chapman DL, Papaioannou VE, Efstratiadis A. Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev 1997; 11:1226-41.
-
(1997)
Genes Dev
, vol.11
, pp. 1226-1241
-
-
Ludwig, T.1
Chapman, D.L.2
Papaioannou, V.E.3
Efstratiadis, A.4
-
85
-
-
0032542216
-
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability
-
Shen SX, Weaver Z, Xu X, Li C, Weinstein M, Chen L, et al. A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. Oncogene 1998; 17:3115-24.
-
(1998)
Oncogene
, vol.17
, pp. 3115-3124
-
-
Shen, S.X.1
Weaver, Z.2
Xu, X.3
Li, C.4
Weinstein, M.5
Chen, L.6
-
86
-
-
0030981170
-
Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation
-
Hakem R, de la Pompa Jl, Elia A, Potter J, Mak TW. Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation. Nat Genet 1997; 16:298-302.
-
(1997)
Nat Genet
, vol.16
, pp. 298-302
-
-
Hakem, R.1
De La Pompa, J.L.2
Elia, A.3
Potter, J.4
Mak, T.W.5
-
87
-
-
0030932869
-
Cancer-susceptibility genes. Gatekeepers and caretakers
-
Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 1997; 386:761-3.
-
(1997)
Nature
, vol.386
, pp. 761-763
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
88
-
-
0034696394
-
Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation
-
Deng CX, Scott F. Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation. Oncogene 2000; 19:1059-64.
-
(2000)
Oncogene
, vol.19
, pp. 1059-1064
-
-
Deng, C.X.1
Scott, F.2
-
89
-
-
0035872860
-
Tumorigenesis in mice carrying a truncating Brca1 mutation
-
Ludwig T, Fisher P, Ganesan S, Efstratiadis A. Tumorigenesis in mice carrying a truncating Brca1 mutation. Genes Dev 2001; 15:1188-93.
-
(2001)
Genes Dev
, vol.15
, pp. 1188-1193
-
-
Ludwig, T.1
Fisher, P.2
Ganesan, S.3
Efstratiadis, A.4
-
90
-
-
0034469155
-
Role of BRCA gene dysfunction in breast and ovarian cancer predisposition
-
Scully R. Role of BRCA gene dysfunction in breast and ovarian cancer predisposition. Breast Cancer Research 2000; 2:324-30.
-
(2000)
Breast Cancer Research
, vol.2
, pp. 324-330
-
-
Scully, R.1
-
91
-
-
0036491931
-
The BRCA1 suppressor hypothesis: An explanation for the tissue-specific tumor development in BRCA1 patients
-
Elledge SJ, Amon A. The BRCA1 suppressor hypothesis: An explanation for the tissue-specific tumor development in BRCA1 patients. Cancer Cell 2002; 1:129-32.
-
(2002)
Cancer Cell
, vol.1
, pp. 129-132
-
-
Elledge, S.J.1
Amon, A.2
-
92
-
-
0038204416
-
BRCA1: The enigma of tissue-specific tumor development
-
Monteiro AN. BRCA1: The enigma of tissue-specific tumor development. Trends Genet 2003; 19:312-5.
-
(2003)
Trends Genet
, vol.19
, pp. 312-315
-
-
Monteiro, A.N.1
-
93
-
-
0142154273
-
Phenotypic effects of heterozygosity for a BRCA2 mutation
-
Warren M, Lord CJ, Masabanda J, Griffin D, Ashworth A. Phenotypic effects of heterozygosity for a BRCA2 mutation. Hum Mol Genet 2003; 12:2645-56.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2645-2656
-
-
Warren, M.1
Lord, C.J.2
Masabanda, J.3
Griffin, D.4
Ashworth, A.5
-
94
-
-
0033400828
-
Genetic analysis of BRCA1 function in a defined tumor cell line
-
Scully R, Ganesan S, Vlasakova K, Chen J, Socolovsky M, Livingston DM. Genetic analysis of BRCA1 function in a defined tumor cell line. Mol Cell 1999; 4:1093-9.
-
(1999)
Mol Cell
, vol.4
, pp. 1093-1099
-
-
Scully, R.1
Ganesan, S.2
Vlasakova, K.3
Chen, J.4
Socolovsky, M.5
Livingston, D.M.6
-
95
-
-
0035874894
-
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation
-
Moynahan ME, Cui TY, Jasin M. Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. Cancer Res 2001; 61:4842-50.
-
(2001)
Cancer Res
, vol.61
, pp. 4842-4850
-
-
Moynahan, M.E.1
Cui, T.Y.2
Jasin, M.3
-
97
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TP, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Current Biology 2000; 10:886-95.
-
(2000)
Current Biology
, vol.10
, pp. 886-895
-
-
Paull, T.P.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
98
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273:5858-68.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
99
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999; 146:905-16.
-
(1999)
J Cell Biol
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
100
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 2001; 276:42462-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
101
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
Ward IM, Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J Biol Chem 2001; 276:47759-62.
-
(2001)
J Biol Chem
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
102
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Lobrich M, Jeggo PA. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res 2004; 64:2390-6.
-
(2004)
Cancer Res
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
103
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, et al. Genomic instability in mice lacking histone H2AX. Science 2002; 296:922-7.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
-
104
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
USA
-
Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, et al. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci USA 2002; 99:8173-8.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 8173-8178
-
-
Bassing, C.H.1
Chua, K.F.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.R.5
Fleming, J.C.6
-
105
-
-
18644367144
-
NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain
-
Kobayashi J, Tauchi H, Sakamoto S, Nakamura A, Morishima K, Matsuura S, et al. NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain. Curr Biol 2002; 12:1846-51.
-
(2002)
Curr Biol
, vol.12
, pp. 1846-1851
-
-
Kobayashi, J.1
Tauchi, H.2
Sakamoto, S.3
Nakamura, A.4
Morishima, K.5
Matsuura, S.6
-
106
-
-
0035972194
-
Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
-
Rappold I, Iwabuchi K, Date T, Chen J. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J Cell Biol 2001; 153:613-20.
-
(2001)
J Cell Biol
, vol.153
, pp. 613-620
-
-
Rappold, I.1
Iwabuchi, K.2
Date, T.3
Chen, J.4
-
107
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 2003; 421:961-6.
-
(2003)
Nature
, vol.421
, pp. 961-966
-
-
Stewart, G.S.1
Wang, B.2
Bignell, C.R.3
Taylor, A.M.4
Elledge, S.J.5
-
108
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 2003; 5:675-9.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
-
109
-
-
0035105291
-
Interaction of the fanconi anemia proteins and BRCA1 in a common pathway
-
Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, et al. Interaction of the fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 2001; 7:249-62.
-
(2001)
Mol Cell
, vol.7
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
Meyn, M.S.4
Timmers, C.5
Hejna, J.6
-
110
-
-
0042671242
-
BRCA1-independent ubiquitination of FANCD2
-
Vandenberg CJ, Gergely F, Ong CY, Pace P, Mallery DL, Hiom K, et al. BRCA1-independent ubiquitination of FANCD2. Mol Cell 2003; 12:247-54.
-
(2003)
Mol Cell
, vol.12
, pp. 247-254
-
-
Vandenberg, C.J.1
Gergely, F.2
Ong, C.Y.3
Pace, P.4
Mallery, D.L.5
Hiom, K.6
-
111
-
-
0346335800
-
BRCA1/BARD1 orthologs required for DNA repair in caenorhabditis elegans
-
Boulton SJ, Martin JS, Polanowska J, Hill DE, Gartner A, Vidal M. BRCA1/BARD1 orthologs required for DNA repair in caenorhabditis elegans. Curr Biol 2004; 14:33-9.
-
(2004)
Curr Biol
, vol.14
, pp. 33-39
-
-
Boulton, S.J.1
Martin, J.S.2
Polanowska, J.3
Hill, D.E.4
Gartner, A.5
Vidal, M.6
|