메뉴 건너뛰기




Volumn 10, Issue 2, 2000, Pages 151-156

Replication and recombination intersect

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DOUBLE STRANDED DNA;

EID: 0034026997     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(00)00059-9     Document Type: Review
Times cited : (84)

References (59)
  • 1
    • 0031025093 scopus 로고    scopus 로고
    • DNA double-strand breaks caused by replication arrest
    • Michel B., Erlich S.D., Uzest M. DNA double-strand breaks caused by replication arrest. EMBO J. 16:1997;430-438.
    • (1997) EMBO J , vol.16 , pp. 430-438
    • Michel, B.1    Erlich, S.D.2    Uzest, M.3
  • 2
    • 0023654911 scopus 로고
    • Helicase action of DnaB protein during replication from the Escherichia coli chromosomal origin in vitro
    • Baker T.A., Sekimizu K., Funnell B.E., Kornberg A. Helicase action of DnaB protein during replication from the Escherichia coli chromosomal origin in vitro. J Biol Chem. 262:1987;6877-6885.
    • (1987) J Biol Chem , vol.262 , pp. 6877-6885
    • Baker, T.A.1    Sekimizu, K.2    Funnell, B.E.3    Kornberg, A.4
  • 3
    • 0022977660 scopus 로고
    • The Escherichia coli dnaB protein is a DNA helicase
    • LeBowitz J.H., McMacken R. The Escherichia coli dnaB protein is a DNA helicase. J Biol Chem. 261:1986;4738-4748.
    • (1986) J Biol Chem , vol.261 , pp. 4738-4748
    • Lebowitz, J.H.1    McMacken, R.2
  • 4
    • 0023646050 scopus 로고
    • The Escherichia coli preprimosome and DnaB helicase can form replication forks that move at the same rate
    • Mok M., Marians K.J. The Escherichia coli preprimosome and DnaB helicase can form replication forks that move at the same rate. J Biol Chem. 262:1987;16644-16654.
    • (1987) J Biol Chem , vol.262 , pp. 16644-16654
    • Mok, M.1    Marians, K.J.2
  • 5
    • 0032582794 scopus 로고    scopus 로고
    • RuvAB acts at arrested replication forks
    • Double-strand break formation and suppression at replication forks that stall in rep mutant strains is dependent on the interconnected action of RecBCD, RuvAB and RuvC, suggesting that these proteins act on a common intermediate - a Holliday-like junction formed by reverse branch migration of the nascent DNA at the fork. An important observation which reveals an initiation pathway for replication-fork reactivation.
    • Seigneur M., Bidnenko V., Ehrlich S.D., Michel B. RuvAB acts at arrested replication forks. Cell. 95:1998;419-430. Double-strand break formation and suppression at replication forks that stall in rep mutant strains is dependent on the interconnected action of RecBCD, RuvAB and RuvC, suggesting that these proteins act on a common intermediate - a Holliday-like junction formed by reverse branch migration of the nascent DNA at the fork. An important observation which reveals an initiation pathway for replication-fork reactivation.
    • (1998) Cell , vol.95 , pp. 419-430
    • Seigneur, M.1    Bidnenko, V.2    Ehrlich, S.D.3    Michel, B.4
  • 6
    • 0031453378 scopus 로고    scopus 로고
    • Processing of recombination intermediates by the RuvABC proteins
    • West S.C. Processing of recombination intermediates by the RuvABC proteins. Annu Rev Genet. 31:1997;213-244.
    • (1997) Annu Rev Genet , vol.31 , pp. 213-244
    • West, S.C.1
  • 7
    • 0019826181 scopus 로고
    • Spontaneous mitotic recombination in mms8-1, an allele of the CDC9 gene of Saccharomyces cerevisiae
    • Montelone B.A., Prakash S., Prakash L. Spontaneous mitotic recombination in mms8-1, an allele of the CDC9 gene of Saccharomyces cerevisiae. J Bacteriol. 147:1981;517-525.
    • (1981) J Bacteriol , vol.147 , pp. 517-525
    • Montelone, B.A.1    Prakash, S.2    Prakash, L.3
  • 8
    • 0021796842 scopus 로고
    • Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae
    • Hartwell L.H., Smith D. Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae. Genetics. 110:1985;381-395.
    • (1985) Genetics , vol.110 , pp. 381-395
    • Hartwell, L.H.1    Smith, D.2
  • 9
    • 0032109778 scopus 로고    scopus 로고
    • Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand break repair
    • Chen C., Umezu K., Kolodner R.D. Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand break repair. Mol Cell. 2:1998;9-22.
    • (1998) Mol Cell , vol.2 , pp. 9-22
    • Chen, C.1    Umezu, K.2    Kolodner, R.D.3
  • 10
    • 0030814759 scopus 로고    scopus 로고
    • Involvement of the yeast DNA polymerase delta in DNA repair in vivo
    • Giot L., Chanet R., Simon M., Facca C., Faye G. Involvement of the yeast DNA polymerase delta in DNA repair in vivo. Genetics. 146:1997;1239-1251.
    • (1997) Genetics , vol.146 , pp. 1239-1251
    • Giot, L.1    Chanet, R.2    Simon, M.3    Facca, C.4    Faye, G.5
  • 11
    • 0031442653 scopus 로고    scopus 로고
    • A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair
    • Tishkoff D.X., Filosi N., Gaida G.M., Kolodner R.D. A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell. 88:1997;253-263.
    • (1997) Cell , vol.88 , pp. 253-263
    • Tishkoff, D.X.1    Filosi, N.2    Gaida, G.M.3    Kolodner, R.D.4
  • 12
    • 0031886721 scopus 로고    scopus 로고
    • The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis
    • Merrill B.J., Holm C. The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis. Genetics. 148:1998;611-624.
    • (1998) Genetics , vol.148 , pp. 611-624
    • Merrill, B.J.1    Holm, C.2
  • 13
    • 0032870740 scopus 로고    scopus 로고
    • A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutants
    • Hydroxyurea-treated cells accumulate single-stranded breaks in nascent DNA which progress to DSBs in rad52 mutants during DNA replication. Similarly, mec1-srf mutations, which are synthetically lethal with rad52, also cause the accumulation of single-strand breaks. These observations suggest that during S phase DSBs arise frequently as a result of DNA replication and are repaired by a recombinational mechanism. This is very suggestive of the CPR pathway in bacteria.
    • Merrill B.J., Holm C. A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutants. Genetics. 153:1999;595-605. Hydroxyurea-treated cells accumulate single-stranded breaks in nascent DNA which progress to DSBs in rad52 mutants during DNA replication. Similarly, mec1-srf mutations, which are synthetically lethal with rad52, also cause the accumulation of single-strand breaks. These observations suggest that during S phase DSBs arise frequently as a result of DNA replication and are repaired by a recombinational mechanism. This is very suggestive of the CPR pathway in bacteria.
    • (1999) Genetics , vol.153 , pp. 595-605
    • Merrill, B.J.1    Holm, C.2
  • 14
    • 0029085781 scopus 로고
    • A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage
    • Paulovich A.G., Hartwell L.H. A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell. 82:1995;841-847.
    • (1995) Cell , vol.82 , pp. 841-847
    • Paulovich, A.G.1    Hartwell, L.H.2
  • 15
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Pâques F., Haber J.E. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 63:1999;349-404.
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 349-404
    • Pâques, F.1    Haber, J.E.2
  • 16
    • 0017366328 scopus 로고
    • Analysis of the frequency and distribution of sister chromatid exchanges in cultured human lymphocytes
    • Crossen P.E., Drets M.E., Arrighi F.E., Johnston D.A. Analysis of the frequency and distribution of sister chromatid exchanges in cultured human lymphocytes. Hum Genet. 35:1977;345-352.
    • (1977) Hum Genet , vol.35 , pp. 345-352
    • Crossen, P.E.1    Drets, M.E.2    Arrighi, F.E.3    Johnston, D.A.4
  • 17
    • 0016840623 scopus 로고
    • Sister chromatid exchanges in human chromosomes from normal individuals and patients with ataxia telangiectasia
    • Galloway S.M., Evans H.J. Sister chromatid exchanges in human chromosomes from normal individuals and patients with ataxia telangiectasia. Cytogenet Cell Genet. 15:1975;17-29.
    • (1975) Cytogenet Cell Genet , vol.15 , pp. 17-29
    • Galloway, S.M.1    Evans, H.J.2
  • 18
    • 0032999346 scopus 로고    scopus 로고
    • Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells
    • Homologous recombination, but not NHEJ, generates SCEs in chicken B-cell lines. This raises the possibility that long-track gene conversions are the product of recombination-directed replication.
    • Sonoda E., Masao S.S., Morrison C., Yamaguch-Iwai Y., Takata M., Takeda S. Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells. Mol Cell Biol. 19:1999;5166-5169. Homologous recombination, but not NHEJ, generates SCEs in chicken B-cell lines. This raises the possibility that long-track gene conversions are the product of recombination-directed replication.
    • (1999) Mol Cell Biol , vol.19 , pp. 5166-5169
    • Sonoda, E.1    Masao, S.S.2    Morrison, C.3    Yamaguch-Iwai, Y.4    Takata, M.5    Takeda, S.6
  • 19
    • 0029117310 scopus 로고
    • What to do at an end: DNA double-strand break-repair
    • Weaver D.T. What to do at an end: DNA double-strand break-repair. Trends Genet. 11:1995;388-392.
    • (1995) Trends Genet , vol.11 , pp. 388-392
    • Weaver, D.T.1
  • 20
    • 0033594509 scopus 로고    scopus 로고
    • Gatekeepers of recombination
    • Haber J.E. Gatekeepers of recombination. Nature. 398:1999;665-667.
    • (1999) Nature , vol.398 , pp. 665-667
    • Haber, J.E.1
  • 21
    • 0032426554 scopus 로고    scopus 로고
    • Recombination and recombination-dependent DNA replication in bacteriophage T4
    • Mosig G. Recombination and recombination-dependent DNA replication in bacteriophage T4. Annu Rev Genet. 32:1998;379-413.
    • (1998) Annu Rev Genet , vol.32 , pp. 379-413
    • Mosig, G.1
  • 22
    • 0028839302 scopus 로고
    • Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4
    • Kreuzer K.N., Saunders M., Weislo L.J., Kreuzer H.W.E. Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4. J Bacteriol. 177:1995;6844-6853.
    • (1995) J Bacteriol , vol.177 , pp. 6844-6853
    • Kreuzer, K.N.1    Saunders, M.2    Weislo, L.J.3    Kreuzer, H.W.E.4
  • 23
    • 0029848499 scopus 로고    scopus 로고
    • Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication
    • George J.W., Kreuer K.N. Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication. Genetics. 143:1996;1507-1520.
    • (1996) Genetics , vol.143 , pp. 1507-1520
    • George, J.W.1    Kreuer, K.N.2
  • 24
    • 0030737725 scopus 로고    scopus 로고
    • Stable DNA replication. Interplay between DNA replication, homologous recombination, and transcription
    • Kogoma T. Stable DNA replication. Interplay between DNA replication, homologous recombination, and transcription. Microbiol Mol Biol Rev. 61:1997;212-238.
    • (1997) Microbiol Mol Biol Rev , vol.61 , pp. 212-238
    • Kogoma, T.1
  • 25
    • 0016813835 scopus 로고
    • DnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form
    • Bouché J-P., Zechel K., Kornberg A. dnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form. J Biol Chem. 250:1975;5995-6001.
    • (1975) J Biol Chem , vol.250 , pp. 5995-6001
    • Bouché, J.-P.1    Zechel, K.2    Kornberg, A.3
  • 26
    • 0008186555 scopus 로고
    • DNA or RNA priming of bacteriophage G4 synthesis by Escherichia coli dnaG protein
    • Wickner S. DNA or RNA priming of bacteriophage G4 synthesis by Escherichia coli dnaG protein. Proc Natl Acad Sci USA. 74:1977;2815-2819.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 2815-2819
    • Wickner, S.1
  • 27
    • 0026777126 scopus 로고
    • Prokaryotic DNA replication
    • Marians K.J. Prokaryotic DNA replication. Annu Rev Biochem. 61:1992;673-719.
    • (1992) Annu Rev Biochem , vol.61 , pp. 673-719
    • Marians, K.J.1
  • 28
    • 0032605883 scopus 로고    scopus 로고
    • PriA: At the crossroads of DNA replication and recombination
    • Marians K.J. PriA: At the crossroads of DNA replication and recombination. Prog Nucleic Acids Res Molec Biol. 63:1999;39-67.
    • (1999) Prog Nucleic Acids Res Molec Biol , vol.63 , pp. 39-67
    • Marians, K.J.1
  • 29
    • 0025836589 scopus 로고
    • Inactivation of the Escherichia coli PriA DNA replication protein induces the SOS response
    • Nurse P., Zavitz K.H., Marians K.J. Inactivation of the Escherichia coli PriA DNA replication protein induces the SOS response. J Bacteriol. 173:1991;6686-6693.
    • (1991) J Bacteriol , vol.173 , pp. 6686-6693
    • Nurse, P.1    Zavitz, K.H.2    Marians, K.J.3
  • 30
    • 0026356063 scopus 로고
    • Replication deficiencies in priA mutants of Escherichia coli lacking the primosomal replication n′ protein
    • Lee E.H., Kornberg A. Replication deficiencies in priA mutants of Escherichia coli lacking the primosomal replication n′ protein. Proc Natl Acad Sci USA. 88:1991;3029-3032.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3029-3032
    • Lee, E.H.1    Kornberg, A.2
  • 31
    • 0028148226 scopus 로고
    • Escherichia coli PriA protein is essential for inducible and constitutive stable DNA replication
    • Masai H., Asai T., Kubota Y., Arai K-I., Kogoma T. Escherichia coli PriA protein is essential for inducible and constitutive stable DNA replication. EMBO J. 13:1994;5338-5345.
    • (1994) EMBO J , vol.13 , pp. 5338-5345
    • Masai, H.1    Asai, T.2    Kubota, Y.3    Arai, K.-I.4    Kogoma, T.5
  • 32
    • 0029960337 scopus 로고    scopus 로고
    • Differential suppression of priA2: Kan phenotypes in Escherichia coli K12 by mutations in priA, lexA, and dnaC
    • Sandler S.J., Sawra H.S., Clark A.J. Differential suppression of priA2: kan phenotypes in Escherichia coli K12 by mutations in priA, lexA, and dnaC. Genetics. 143:1996;5-13.
    • (1996) Genetics , vol.143 , pp. 5-13
    • Sandler, S.J.1    Sawra, H.S.2    Clark, A.J.3
  • 33
    • 0029863634 scopus 로고    scopus 로고
    • The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair
    • Kogoma T., Cadwell G.W., Barnard K.G., Asai T. The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair. J Bacteriol. 178:1996;1258-1264.
    • (1996) J Bacteriol , vol.178 , pp. 1258-1264
    • Kogoma, T.1    Cadwell, G.W.2    Barnard, K.G.3    Asai, T.4
  • 34
    • 0026320399 scopus 로고
    • Dissecting the functional role of PriA protein-catalyzed primosome assembly in Escherichia coli DNA replication
    • Zavitz K.H., Marians K.J. Dissecting the functional role of PriA protein-catalyzed primosome assembly in Escherichia coli DNA replication. Mol Microbiol. 5:1991;2869-2873.
    • (1991) Mol Microbiol , vol.5 , pp. 2869-2873
    • Zavitz, K.H.1    Marians, K.J.2
  • 35
    • 0030852247 scopus 로고    scopus 로고
    • The DNA replication protein PriA and the recombination protein RecG bind D-loops
    • McGlynn P., Al-Deib A.A., Liu J., Marians K.J., Lloyd R.G. The DNA replication protein PriA and the recombination protein RecG bind D-loops. J Mol Biol. 270:1997;212-221.
    • (1997) J Mol Biol , vol.270 , pp. 212-221
    • McGlynn, P.1    Al-Deib, A.A.2    Liu, J.3    Marians, K.J.4    Lloyd, R.G.5
  • 36
    • 0033609883 scopus 로고    scopus 로고
    • Two modes of PriA binding to DNA
    • Nurse P., Liu J., Marians K.J. Two modes of PriA binding to DNA. J Biol Chem. 274:1999;25025-25032.
    • (1999) J Biol Chem , vol.274 , pp. 25025-25032
    • Nurse, P.1    Liu, J.2    Marians, K.J.3
  • 37
    • 0033616683 scopus 로고    scopus 로고
    • Replication fork assembly at recombination intermediates is required for bacterial growth
    • The authors show that in vitro replication-fork assembly at a D loop is mediated by formation of the restart primosome. This is a major step in replication-fork reactivation in bacteria.
    • Liu J., Xu L., Sandler S.J., Marians K.J. Replication fork assembly at recombination intermediates is required for bacterial growth. Proc Natl Acad Sci USA. 96:1999;3552-3555. The authors show that in vitro replication-fork assembly at a D loop is mediated by formation of the restart primosome. This is a major step in replication-fork reactivation in bacteria.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3552-3555
    • Liu, J.1    Xu, L.2    Sandler, S.J.3    Marians, K.J.4
  • 38
    • 0033988501 scopus 로고    scopus 로고
    • Role of PriA in replication fork reactivation in Escherichia coli
    • Sandler S.J., Marians K.J. Role of PriA in replication fork reactivation in Escherichia coli. J Bacteriol. 182:2000;9-13.
    • (2000) J Bacteriol , vol.182 , pp. 9-13
    • Sandler, S.J.1    Marians, K.J.2
  • 39
    • 0032916453 scopus 로고    scopus 로고
    • Recovery of DNA replication in UV-irradiated Escherichia coli requires both excision repair and RecF protein function
    • Courcelle J., Growley D.J., Hanawalt P.C. Recovery of DNA replication in UV-irradiated Escherichia coli requires both excision repair and RecF protein function. J Bacteriol. 181:1999;916-922.
    • (1999) J Bacteriol , vol.181 , pp. 916-922
    • Courcelle, J.1    Growley, D.J.2    Hanawalt, P.C.3
  • 40
    • 0027265542 scopus 로고
    • Degradation of individual chromosomes in recA mutants of Escherichia coli
    • Skarstad K., Boye E. Degradation of individual chromosomes in recA mutants of Escherichia coli. J Bacteriol. 175:1993;5505-5509.
    • (1993) J Bacteriol , vol.175 , pp. 5505-5509
    • Skarstad, K.1    Boye, E.2
  • 41
    • 0025630657 scopus 로고
    • Gene Conversion tracts stimulated by HOT1-promoted transcription are long and continuous
    • Voelkel-Meiman K., Roeder G.S. Gene Conversion tracts stimulated by HOT1-promoted transcription are long and continuous. Genetics. 126:1990;851-867.
    • (1990) Genetics , vol.126 , pp. 851-867
    • Voelkel-Meiman, K.1    Roeder, G.S.2
  • 42
    • 0029947714 scopus 로고    scopus 로고
    • Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication
    • Malkova A., Ivanov E.L., Haber J.E. Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci USA. 93:1996;7131-7136.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7131-7136
    • Malkova, A.1    Ivanov, E.L.2    Haber, J.E.3
  • 43
    • 0030760609 scopus 로고    scopus 로고
    • 'Break copy' duplication: A model for chromosome fragment formation in Saccharomyces cerevisiae
    • Morrow D.M., Connelly C., Hieter P. 'Break copy' duplication: a model for chromosome fragment formation in Saccharomyces cerevisiae. Genetics. 147:1997;371-382.
    • (1997) Genetics , vol.147 , pp. 371-382
    • Morrow, D.M.1    Connelly, C.2    Hieter, P.3
  • 44
    • 0033525095 scopus 로고    scopus 로고
    • Double-strand break repair in yeast requires both leading and lagging strand DNA polymerises
    • Double-strand break repair is shown to require essentially all of the known components of the replication fork. This indicates that even if the region that is duplicated by replication is limited to the gap created by resection of the break, the recombination and replication machinery are able to cooperate to repair DNA damage.
    • Holmes A.M., Haber J.E. Double-strand break repair in yeast requires both leading and lagging strand DNA polymerises. Cell. 96:1999;415-424. Double-strand break repair is shown to require essentially all of the known components of the replication fork. This indicates that even if the region that is duplicated by replication is limited to the gap created by resection of the break, the recombination and replication machinery are able to cooperate to repair DNA damage.
    • (1999) Cell , vol.96 , pp. 415-424
    • Holmes, A.M.1    Haber, J.E.2
  • 45
    • 0032574750 scopus 로고    scopus 로고
    • Homology-directed repair is a major double-strand break repair pathway in mammalian cells
    • Physical analysis reveals that as much as 50% of the products of repair from a chromosomal DSB generated by the use of a rare-cutting endonuclease can be attributed to HR. A revealing and informative approach to the study of recombination in mammalian systems
    • Liang F., Han M., Romanienko P.J., Jasin M. Homology-directed repair is a major double-strand break repair pathway in mammalian cells. Proc Natl Acad Sci USA. 95:1998;5172-5177. Physical analysis reveals that as much as 50% of the products of repair from a chromosomal DSB generated by the use of a rare-cutting endonuclease can be attributed to HR. A revealing and informative approach to the study of recombination in mammalian systems.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5172-5177
    • Liang, F.1    Han, M.2    Romanienko, P.J.3    Jasin, M.4
  • 46
    • 0032535036 scopus 로고    scopus 로고
    • Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocation
    • Homologous recombination between repeats on heterologous chromosomes is stimulated 1000-fold by DSB formation. Some long-tract gene-conversion events are likely to involve recombination-directed replication. Thus, the tools exist in mammalian cells for a housekeeping function that combines recombination and replication to repair replication forks arrested by encountering a nick in the template strand.
    • Richardson C., Moynahan M.E., Jasin M. Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocation. Genes Dev. 12:1998;3831-3842. Homologous recombination between repeats on heterologous chromosomes is stimulated 1000-fold by DSB formation. Some long-tract gene-conversion events are likely to involve recombination-directed replication. Thus, the tools exist in mammalian cells for a housekeeping function that combines recombination and replication to repair replication forks arrested by encountering a nick in the template strand.
    • (1998) Genes Dev , vol.12 , pp. 3831-3842
    • Richardson, C.1    Moynahan, M.E.2    Jasin, M.3
  • 47
    • 0033598437 scopus 로고    scopus 로고
    • Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination
    • This paper shows that a gene product known to be required for the repair of DNA damage is required for DSB-initiated HR between sister chromatids. This echoes the situation in bacteria where sensitivity to UV-irradiation of mutations in genes such as priA is coupled to a HR defect and can be attributed to a defect in replication fork reactivation.
    • Johnson R.D., Liu N., Jasin M. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature. 401:1999;397-399. This paper shows that a gene product known to be required for the repair of DNA damage is required for DSB-initiated HR between sister chromatids. This echoes the situation in bacteria where sensitivity to UV-irradiation of mutations in genes such as priA is coupled to a HR defect and can be attributed to a defect in replication fork reactivation.
    • (1999) Nature , vol.401 , pp. 397-399
    • Johnson, R.D.1    Liu, N.2    Jasin, M.3
  • 48
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • ••], except that the HR was measured using a GFP fluorescence assay.
    • ••], except that the HR was measured using a GFP fluorescence assay.
    • (1999) Genes Dev , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3    Jasin, M.4
  • 49
    • 0033213392 scopus 로고    scopus 로고
    • Brca1 controls homology-directed DNA repair
    • The authors show that a protein associated with increased occurrence of breast and ovarian tumors and known to associate with RAD51 is involved in DSB-initiated HR, but not NHEJ, between direct repeats on the same chromosome. This suggests that that the increased genome instability observed in the absence of Brca1 results from the lack of a housekeeping function that acts to repair DSBs. Is this an intimation of mammalian CPR? Could be!
    • Moynahan M.E., Chiu J.W., Koller B.H., Jasin M. Brca1 controls homology-directed DNA repair. Mol Cell. 4:1999;511-518. The authors show that a protein associated with increased occurrence of breast and ovarian tumors and known to associate with RAD51 is involved in DSB-initiated HR, but not NHEJ, between direct repeats on the same chromosome. This suggests that that the increased genome instability observed in the absence of Brca1 results from the lack of a housekeeping function that acts to repair DSBs. Is this an intimation of mammalian CPR? Could be!
    • (1999) Mol Cell , vol.4 , pp. 511-518
    • Moynahan, M.E.1    Chiu, J.W.2    Koller, B.H.3    Jasin, M.4
  • 50
    • 0022968662 scopus 로고
    • Radiation-induced chromosome damage in X-ray sensitive mutants (xrs) of the Chinese hamater ovary cell line
    • Kemp L.M., Jeggo P.A. Radiation-induced chromosome damage in X-ray sensitive mutants (xrs) of the Chinese hamater ovary cell line. Mutat Res. 166:1986;255-263.
    • (1986) Mutat Res , vol.166 , pp. 255-263
    • Kemp, L.M.1    Jeggo, P.A.2
  • 56
    • 0029909565 scopus 로고    scopus 로고
    • A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
    • Lim D-S., Hasty P. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol. 16:1996;7133-7145.
    • (1996) Mol Cell Biol , vol.16 , pp. 7133-7145
    • Lim, D.-S.1    Hasty, P.2
  • 58
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and s-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • 1 and early S. Thus, the availability of the sister chromatid plays a role in dictating the method of repair. One would therefore expect that the DNA replication machinery will be available when most HR is occurring.
    • 1 and early S. Thus, the availability of the sister chromatid plays a role in dictating the method of repair. One would therefore expect that the DNA replication machinery will be available when most HR is occurring.
    • (1998) EMBO J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, S.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utzumi, H.6    Yamaguchi-Iwai, Y.7    Shinohara, A.8    Takeda, S.9
  • 59
    • 0032749835 scopus 로고    scopus 로고
    • Double-strand-break repair recombination in Escherichia coli: Physical evidence for a DNA replication mechanism in vivo
    • The authors provide physical evidence that RecBCD-mediated repair of double-strand breaks in E. coli proceeds by a pathway that involves participation of the cellular replicase, the DNA polymerase III holoenzyme. This is an important observation confirming that recombination-directed replication initiates at recombination intermediates under conditions of normal growth.
    • Motamedi M.R., Szigety S.K., Rosenberg S.M. Double-strand-break repair recombination in Escherichia coli: physical evidence for a DNA replication mechanism in vivo. Genes Dev. 13:1999;2889-2903. The authors provide physical evidence that RecBCD-mediated repair of double-strand breaks in E. coli proceeds by a pathway that involves participation of the cellular replicase, the DNA polymerase III holoenzyme. This is an important observation confirming that recombination-directed replication initiates at recombination intermediates under conditions of normal growth.
    • (1999) Genes Dev , vol.13 , pp. 2889-2903
    • Motamedi, M.R.1    Szigety, S.K.2    Rosenberg, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.