-
1
-
-
0033710938
-
Clinical ascertainment of nijmegen breakage syndrome (nbs) and prevalence of the major mutation, 657del5, in three slav populations
-
R Varon, E Seemanova, K Chrzanowska, O Hnateyko, D Piekutowska-Abramczuk, M Krajewska-Walasek, J Sykut-Cegielska, K Sperling, A Reis. Clinical ascertainment of Nijmegen breakage syndrome (NBS) and prevalence of the major mutation, 657del5, in three Slav populations. Eur J Hum Genet 8:900-902, 2000.
-
(2000)
Eur J Hum Genet
, vol.8
, pp. 900-902
-
-
Varon, R.E.1
Seemanova, K.2
Chrzanowska, O.3
Hnateyko, D.4
Piekutowska-Abramczuk, M.5
Krajewska-Walasek, J.6
Sykut-Cegielska, K.7
Sperling Reis, A.8
-
2
-
-
0030022497
-
Nijmegen breakage syndrome
-
I van der Burgt, KH Chrzanowska, D Smeets, C Weemaes. Nijmegen breakage syndrome. J Med Genet 33:153-156, 1996.
-
(1996)
J Med Genet
, vol.33
, pp. 153-156
-
-
Van Der Burgt, I.1
Chrzanowska, K.H.2
Smeets, D.3
Weemaes, C.4
-
3
-
-
0031466618
-
Ataxia-telangiectasia and the nijmegen breakage syndrome: Related disorders but genes apart
-
Y Shiloh. Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart. Annu Rev Genet 31:635-662, 1997.
-
(1997)
Annu Rev Genet
, vol.31
, pp. 635-662
-
-
Shiloh, Y.1
-
4
-
-
0017782437
-
Evolution of ageing
-
TB Kirkwood. Evolution of ageing. Nature 270:301-304, 1977.
-
(1977)
Nature
, vol.270
, pp. 301-304
-
-
Kirkwood, T.B.1
-
5
-
-
0030447280
-
Human senescence
-
TB Kirkwood. Human senescence. Bioessays 18:1009-1016, 1996.
-
(1996)
Bioessays
, vol.18
, pp. 1009-1016
-
-
Kirkwood, T.B.1
-
6
-
-
0033548034
-
Unlimited mileage from telomerase?
-
T de Lange, RA DePinho. Unlimited mileage from telomerase? Science 283:947-949, 1999.
-
(1999)
Science
, vol.283
, pp. 947-949
-
-
De Lange, T.1
DePinho, R.A.2
-
7
-
-
0002229288
-
Ataxia-telangiectasia variants
-
HD Ochs, CIE Smith, JM Puck, eds., Oxford, UK: Oxford University Press
-
RD Wegner, KH Chrzanowska, K Sperling, M Stumm. Ataxia-telangiectasia variants. In: HD Ochs, CIE Smith, JM Puck, eds. Primary Immunodeficiency Diseases: A Molecular and Genetic Approach. Oxford, UK: Oxford University Press, 1998, pp 324-334.
-
(1998)
Primary Immunodeficiency Diseases: A Molecular and Genetic Approach
, pp. 324-334
-
-
Wegner, R.1
Chrzanowska, K.2
Sperling Stumm, M.3
-
8
-
-
0021946340
-
Familial microcephaly with normal intelligence, immunodeficiency, and risk for lym-phoreticular malignancies: A new autosomal recessive disorder
-
E Seemanova, E Passarge, D Beneskova, J Houstek, P Kasal, M Sevcikova. Familial microcephaly with normal intelligence, immunodeficiency, and risk for lym-phoreticular malignancies: a new autosomal recessive disorder. Am J Med Genet 20:639-648, 1985.
-
(1985)
Am J Med Genet
, vol.20
, pp. 639-648
-
-
Seemanova, E.E.1
Passarge, D.2
Beneskova, J.3
Houstek, P.4
Kasal Sevcikova, M.5
-
9
-
-
0029056905
-
G lyson-wojciechowska. Eleven polish patients with microcephaly, immunodeficiency, and chromosomal instability: The nijmegen breakage syndrome
-
KH Chrzanowska, WJ Kleijer, M Krajewska-Walasek, M Bialecka, A Gutkowska, B Goryluk-Kozakiewicz, J Michalkiewicz, J Stachowski, H Gregorek, G Lyson-Wojciechowska. Eleven Polish patients with microcephaly, immunodeficiency, and chromosomal instability: The Nijmegen breakage syndrome. Am J Med Genet 57:462-471, 1995.
-
(1995)
Am J Med Genet
, vol.57
, pp. 462-471
-
-
Chrzanowska, K.H.1
Kleijer, W.J.2
Krajewska-Walasek, M.3
Bialecka, M.4
Gutkowska, A.5
Goryluk-Kozakiewicz, B.6
Michalkiewicz, J.7
Stachowski, J.8
Gregorek, H.9
-
10
-
-
0019478575
-
A new chromosomal instability disorder: The nijmegen breakage syndrome
-
CM Weemaes, TW Hustinx, JM Scheres, PJ van Munster, JA Bakkeren, RD Taal-man. A new chromosomal instability disorder: the Nijmegen breakage syndrome. Acta Paediatr Scand 70:557-564, 1981.
-
(1981)
Acta Paediatr Scand
, vol.70
, pp. 557-564
-
-
Weemaes, C.1
Hustinx, J.M.2
Scheres, P.J.3
Van Munster, J.A.4
Bakkeren Taal-Man, R.D.5
-
11
-
-
0028200107
-
Radiosensitivity of ataxia-telangiectasia, x-linked agammaglobulinemia, and related syndromes using a modified colony survival assay
-
YK Huo, Z Wang, JH Hong, L Chessa, WH McBride, SL Perlman, RA Gatti. Radiosensitivity of ataxia-telangiectasia, X-linked agammaglobulinemia, and related syndromes using a modified colony survival assay. Cancer Res 54:2544-2547, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 2544-2547
-
-
Huo, Y.K.Z.1
Wang, J.H.2
Hong, L.3
Chessa, W.H.4
McBride, S.L.5
Perlman Gatti, R.A.6
-
12
-
-
0022290578
-
On the nature of a “dna-processing” defect in ataxia-telangiectasia
-
P Hanawalt, R Painter. On the nature of a “DNA-processing” defect in ataxia-telangiectasia. Kroc Found Ser 19:67-71, 1985.
-
(1985)
Kroc Found Ser
, vol.19
, pp. 67-71
-
-
Hanawalt, P.1
Painter, R.2
-
13
-
-
0000770165
-
Nijmegen breakage syndrome
-
The International Nijmegen Breakage Syndrome Study Group. Nijmegen breakage syndrome. Arch Dis Child 82:400-406, 2000.
-
(2000)
Arch Dis Child
, vol.82
, pp. 400-406
-
-
-
14
-
-
0342680014
-
Cranial mri in the nijmegen breakage syndrome
-
M Bekiesinska-Figatowska, KH Chrzanowska, J Sikorska, J Walecki, M Krajew-ska-Walasek, S Jozwiak, WJ Kleijer. Cranial MRI in the Nijmegen breakage syndrome. Neuroradiology 42:43-47, 2000.
-
(2000)
Neuroradiology
, vol.42
, pp. 43-47
-
-
Bekiesinska-Figatowska, M.K.1
Chrzanowska, J.2
Sikorska, J.3
Walecki, M.4
Krajew-Ska-Walasek, S.5
Jozwiak Kleijer, W.J.6
-
15
-
-
0028017698
-
Postmortem findings in the nijmegen breakage syndrome
-
CA Van de Kaa, CM Weemaes, P Wesseling, HE Schaafsma, A Haraldsson, RA De Weger. Postmortem findings in the Nijmegen breakage syndrome. Pediatr Pathol 14:787-796, 1994.
-
(1994)
Pediatr Pathol
, vol.14
, pp. 787-796
-
-
Van De Kaa, C.A.1
Weemaes, C.M.2
Wesseling, P.3
Schaafsma, H.E.4
Haraldsson, A.5
De Weger, R.A.6
-
16
-
-
0028884148
-
Severe microcephaly with normal intellectual development: The nijmegen breakage syndrome
-
AJ Green, JR Yates, AM Taylor, P Biggs, GM McGuire, CM McConville, CJ Billing, ND Barnes. Severe microcephaly with normal intellectual development: the Nijmegen breakage syndrome. Arch Dis Child 73:431-434, 1995.
-
(1995)
Arch Dis Child
, vol.73
, pp. 431-434
-
-
Green, A.1
Yates, A.M.2
Taylor, P.3
Biggs, G.M.4
McGuire, C.M.5
McConville, C.J.6
Billing Barnes, N.D.7
-
18
-
-
0033994079
-
Non-hodgkin’s lymphoma in pediatric patients with chromosomal breakage syndromes (at and nbs). Wxperience from the bfm trials
-
K Seidemann, G Henze, JD Beck, A Sauerbrey, J Kuhl, G Mann, A Reiter. Non-Hodgkin’s lymphoma in pediatric patients with chromosomal breakage syndromes (AT and NBS). Experience from the BFM trials. Ann Oncol 11:141-145, 2000.
-
(2000)
Ann Oncol
, vol.11
, pp. 141-145
-
-
Seidemann, K.1
Henze, G.2
Beck, J.D.3
Sauerbrey, A.4
Kuhl, J.5
Mann, G.6
Reiter, A.7
-
19
-
-
0033761081
-
T-cell prolymphocytic leukaemia: Antigen receptor gene rearrangement and a novel mode of mtcp1 b1 activation
-
PJ De Schouwer, MJ Dyer, VB Brito-Babapulle, E Matutes, D Catovsky, MR Yuille. T-cell prolymphocytic leukaemia: antigen receptor gene rearrangement and a novel mode of MTCP1 B1 activation. Br J Haematol 110:831-838, 2000.
-
(2000)
Br J Haematol
, vol.110
, pp. 831-838
-
-
De Schouwer, P.1
Dyer, V.B.2
Brito-Babapulle, E.3
Matutes, D.4
Catovsky Yuille, M.R.5
-
20
-
-
0031989598
-
Reversible epstein-barr virus associated t cell non-hodgkin’s lymphoma in a patient with rheumatoid arthritis undergoing chronic immunosuppressive therapy
-
D Vassilopoulos, J Waltuck, G Clarke, DC Farhi, J Williams, MP Fanucchi. Reversible Epstein-Barr virus associated T cell non-Hodgkin’s lymphoma in a patient with rheumatoid arthritis undergoing chronic immunosuppressive therapy. J Rheumatol 25:389-391, 1998.
-
(1998)
J Rheumatol
, vol.25
, pp. 389-391
-
-
Vassilopoulos, D.J.1
Waltuck, G.2
Clarke, D.C.3
Farhi, J.4
Williams Fanucchi, M.P.5
-
21
-
-
0028300489
-
Posttransplant t-cell lymphoma. report of three cases and A review of the literature
-
J van Gorp, H Doornewaard, LF Verdonck, C Klopping, PF Vos, JG van den Tweel. Posttransplant T-cell lymphoma. Report of three cases and A review of the literature. Cancer 73:3064-3072, 1994.
-
(1994)
Cancer
, vol.73
, pp. 3064-3072
-
-
Van Gorp, J.1
Doornewaard, H.2
Verdonck, L.F.3
Klopping, C.4
Vos, P.F.5
van Den Tweel, J.G.6
-
22
-
-
0033854211
-
The effect of age on the b-cell repertoire
-
ME Weksler, P Szabo. The effect of age on the B-cell repertoire. J Clin Immunol 20:240-249, 2000.
-
(2000)
J Clin Immunol
, vol.20
, pp. 240-249
-
-
Weksler, M.E.1
Szabo, P.2
-
23
-
-
0034194058
-
Shortage of circulating naive cd8(+) t cells provides new insights on immunodeficiency in ageing
-
FF Fagnoni, R Vescovini, G Passeri, G Bologna, M Pedrazzoni, G Lavagetto, A Casti, C Franceschi, M Passeri, P Sansoni. Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in ageing. Blood 95:2860-2868, 2000.
-
(2000)
Blood
, vol.95
, pp. 2860-2868
-
-
Fagnoni, F.F.R.1
Vescovini, G.2
Passeri, G.3
Bologna, M.4
Pedrazzoni, G.5
Lavagetto, A.6
Casti, C.7
Franceschi, M.8
Passeri Sansoni, P.9
-
24
-
-
0032696553
-
The immune system in the elderly. Iii. Innate immunity
-
L Ginaldi, M DeMartinis, AD Ostilio, L Marini, MF Loreto, D Quaglino. The immune system in the elderly. III. Innate immunity. Immunol Res 20:117-126, 1999.
-
(1999)
Immunol Res
, vol.20
, pp. 117-126
-
-
Ginaldi, L.1
DeMartinis, M.2
Ostilio, A.D.3
Marini, L.4
Loreto, M.F.5
Quaglino, D.6
-
25
-
-
0025268280
-
An increased risk for malignant neoplasms in heterozygotes for a syndrome of microcephaly, normal intelligence, growth retardation, remarkable facies, immunodeficiency and chromosomal instability
-
E Seemanova. An increased risk for malignant neoplasms in heterozygotes for a syndrome of microcephaly, normal intelligence, growth retardation, remarkable facies, immunodeficiency and chromosomal instability. Mutat Res 238:321-324, 1990.
-
(1990)
Mutat Res
, vol.238
, pp. 321-324
-
-
Seemanova, E.1
-
26
-
-
0034085362
-
No evidence for a major role of heterozygous deletion 657del5 within the nbs1 gene in the pathogenesis of non-hodgkin’s lymphoma of childhood and adolescence
-
M Stanulla, M Stumm, BO Dieckvoss, K Seidemann, V Schemmel, A Muller-Brechlin, M Schrappe, K Welte, A Reiter. No evidence for a major role of heterozygous deletion 657del5 within the NBS1 gene in the pathogenesis of non-Hodgkin’s lymphoma of childhood and adolescence. Br J Haematol 109:117-120, 2000.
-
(2000)
Br J Haematol
, vol.109
, pp. 117-120
-
-
Stanulla, M.M.1
Stumm, B.O.2
Dieckvoss, K.3
Seidemann, V.4
Schemmel, A.5
Muller-Brechlin, M.6
Schrappe, K.7
Welte Reiter, A.8
-
27
-
-
0033869097
-
Absence of mutations in the nbs1 gene in b-cell malignant lymphoma patients
-
S Hama, S Matsuura, H Tauchi, J Sawada, C Kato, F Yamasaki, H Yoshioka, K Sugiyama, K Arita, K Kurisu, N Kamada, Y Heike, K Komatsu. Absence of mutations in the NBS1 gene in B-cell malignant lymphoma patients. Anticancer Res 20:1897-1900, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 1897-1900
-
-
Hama, S.S.1
Matsuura, H.2
Tauchi, J.3
Sawada, C.4
Kato, F.5
Yamasaki, H.6
Yoshioka, K.7
Sugiyama, K.8
Arita, K.9
Kurisu, N.10
Kamada, Y.11
Heike Komatsu, K.12
-
28
-
-
0035306631
-
No evidence for deletions of the nbs1 gene in lymphomas
-
M Stumm, A von Ruskowsky, R Siebert, S Harder, R Varon, P Wieacker, B Schlegelberger. No evidence for deletions of the NBS1 gene in lymphomas. Cancer Genet Cytogenet 126:60-62, 2001
-
(2001)
Cancer Genet Cytogenet
, vol.126
, pp. 60-62
-
-
Stumm, M.A.1
Von Ruskowsky, R.2
Siebert, S.3
Harder, R.4
Varon, P.5
Wieacker Schlegelberger, B.6
-
29
-
-
0035328489
-
Seeger. Mutations in the nijmegen breakage syndrome gene (nbs1) in childhood acute lymphoblastic leukemia (all)
-
R Varon, A Reis, G Henze, HG von Einsiedel, K Sperling, K Seeger. Mutations in the Nijmegen breakage syndrome gene (NBS1) in childhood acute lymphoblastic leukemia (ALL). Cancer Res 61:3570-3572, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 3570-3572
-
-
R Varon, A.1
Reis, G.2
Henze, H.G.3
Von Einsiedel, K.4
Sperling, K.5
-
30
-
-
0034146132
-
Allelic imbalance at nbs1 is frequent in both proximal and distal colorectal carcinoma
-
N Uhrhammer, JO Bay, S Gosse-Brun, F Kwiatkowski, P Rio, A Daver, YJ Bignon. Allelic imbalance at NBS1 is frequent in both proximal and distal colorectal carcinoma. Oncol Rep 7:427-431, 2000.
-
(2000)
Oncol Rep
, vol.7
, pp. 427-431
-
-
Uhrhammer, N.J.1
Bay, S.2
Gosse-Brun, F.3
Kwiatkowski, P.4
Rio, A.5
Daver Bignon, Y.J.6
-
31
-
-
0032792820
-
Determination of the frequency of the common 657del5 nijmegen breakage syndrome mutation in the german population. No association with risk of breast cancer
-
F Carlomagno, J Chang-Claude, AM Dunning, BA Ponder. Determination of the frequency of the common 657Del5 Nijmegen breakage syndrome mutation in the German population. No association with risk of breast cancer. Genes Chromosomes Cancer 25:393-395, 1999.
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 393-395
-
-
Carlomagno, F.J.1
Chang-Claude, A.M.2
Dunning Ponder, B.A.3
-
32
-
-
0022973416
-
Hypersensitivity of cells from a new chromosomal-breakage syndrome to dna-damaging agents
-
J Nove, JB Little, PJ Mayer, P Troilo, WW Nichols. Hypersensitivity of cells from a new chromosomal-breakage syndrome to DNA-damaging agents. Mutat Res 163:255-262, 1986.
-
(1986)
Mutat Res
, vol.163
, pp. 255-262
-
-
Nove, J.J.1
Little, P.J.2
Mayer, P.3
Troilo Nichols, W.W.4
-
34
-
-
0033008552
-
Immortalization and characterization of nijmegen breakage syndrome fibroblasts
-
M Kraakman-van der Zwet, WJ Overkamp, AA Friedl, B Klein, GW Verhaegh, NG Jaspers, AT Midro, F Eckardt-Schupp, PH Lohman, MZ Zdzienicka. Immortalization and characterization of Nijmegen breakage syndrome fibroblasts. Mutat Res 434:17-27, 1999.
-
(1999)
Mutat Res
, vol.434
, pp. 17-27
-
-
Kraakman-Van Der Zwet, M.1
Overkamp, W.J.2
Friedl, A.A.3
Klein, B.4
Verhaegh, G.W.5
Jaspers, N.G.6
Midro, A.T.7
Eckardt-Schupp, F.8
Lohman, P.H.9
Zdzienicka, M.Z.10
-
35
-
-
0035254654
-
Sources of variation in patient response to radiation treatment
-
NE Crompton, YQ Shi, GC Emery, L Wisser, H Blattmann, A Maier, L Li, D Schindler, H Ozsahin, M Ozsahin. Sources of variation in patient response to radiation treatment. Int J Radiat Oncol Biol Phys 49:547-554, 2001.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 547-554
-
-
Crompton, N.1
Shi, G.C.2
Emery, L.3
Wisser, H.4
Blattmann, A.5
Maier, L.6
Li, D.7
Schindler, H.8
Ozsahin Ozsahin, M.9
-
36
-
-
0031036995
-
Rad9, rad17, and rad24 are required for s phase regulation in saccharomyces cerevisiae in response to dna damage
-
AG Paulovich, RU Margulies, BM Garvik, LH Hartwell. RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cerevisiae in response to DNA damage. Genetics 145:45-62, 1997.
-
(1997)
Genetics
, vol.145
, pp. 45-62
-
-
Paulovich, A.1
Margulies, B.M.2
Garvik Hartwell, L.H.3
-
37
-
-
0030933152
-
The genetic defect in ataxia-telangiectasia
-
MF Lavin, Y Shiloh. The genetic defect in ataxia-telangiectasia. Annu Rev Immunol 15:177-202, 1997.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 177-202
-
-
Lavin, M.F.1
Shiloh, Y.2
-
38
-
-
0030786912
-
Nijmegen breakage syndrome cells fail to induce the p53-mediated dna damage response following exposure to ionizing radiation
-
W Jongmans, M Vuillaume, K Chrzanowska, D Smeets, K Sperling, J Hall. Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation. Mol Cell Biol 17:5016-5022, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5016-5022
-
-
Jongmans, W.M.1
Vuillaume, K.2
Chrzanowska, D.3
Smeets, K.4
Sperling Hall, J.5
-
39
-
-
0032567642
-
Radiation induction of p53 in cells from nijmegen breakage syndrome is defective but not similar to ataxia-telangiectasia
-
K Matsuura, T Balmukhanov, H Tauchi, C Weemaes, D Smeets, K Chrzanowska, S Endou, S Matsuura, K Komatsu. Radiation induction of p53 in cells from Nijmegen breakage syndrome is defective but not similar to ataxia-telangiectasia. Biochem Biophys Res Commun 242:602-607, 1998.
-
(1998)
Biochem Biophys Res Commun
, vol.242
, pp. 602-607
-
-
Matsuura, K.T.1
Balmukhanov, H.2
Tauchi, C.3
Weemaes, D.4
Smeets, K.5
Chrzanowska, S.6
Endou, S.7
Matsuura Komatsu, K.8
-
40
-
-
0032101583
-
Characterization of cell cycle checkpoint responses after ionizing radiation in nijmegen breakage syndrome cells
-
V Yamazaki, RD Wegner, CU Kirchgessner. Characterization of cell cycle checkpoint responses after ionizing radiation in Nijmegen breakage syndrome cells. Cancer Res 58:2316-2322, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 2316-2322
-
-
Yamazaki, V.R.1
Wegner Kirchgessner, C.U.2
-
41
-
-
0033053329
-
Impaired p53-mediated dna damage response, cell-cycle disturbance and chromosome aberrations in nijmegen breakage syndrome lymphoblastoid cell lines
-
A Antoccia, M Stumm, K Saar, R Ricordy, P Maraschio, C Tanzarella. Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines. Int J Radiat Biol 75:583-591, 1999.
-
(1999)
Int J Radiat Biol
, vol.75
, pp. 583-591
-
-
Antoccia, A.M.1
Stumm, K.2
Saar, R.3
Ricordy, P.4
Maraschio Tanzarella, C.5
-
42
-
-
0034282753
-
Radiosensitivity in nijmegen breakage syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects
-
PM Girard, N Foray, M Stumm, A Waugh, E Riballo, RS Maser, WP Phillips, J Petrini, CF Arlett, PA Jeggo. Radiosensitivity in Nijmegen breakage syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. Cancer Res 60:4881-4888, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 4881-4888
-
-
Girard, P.M.1
Foray, N.2
Stumm, M.3
Waugh, A.4
Riballo, E.5
Maser, R.S.6
Phillips, W.P.7
Petrini, J.8
Arlett, C.F.9
Jeggo, P.A.10
-
43
-
-
0008158443
-
Radiosensitivity in ataxia-telangiectasia. a new explanation
-
RB Painter, BR Young. Radiosensitivity in ataxia-telangiectasia. A new explanation. Proc Natl Acad Sci USA 77:7315-7317, 1980.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 7315-7317
-
-
Painter, R.B.1
Young, B.R.2
-
44
-
-
0019166395
-
Effect of ionizing radiation on dna synthesis in ataxia telangiectasia cells
-
J Houldsworth, MF Lavin. Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells. Nucleic Acids Res 8:3709-3720, 1980.
-
(1980)
Nucleic Acids Res
, vol.8
, pp. 3709-3720
-
-
Houldsworth, J.1
Lavin, M.F.2
-
45
-
-
0020684242
-
Hypersensitivity to ionizing radiation, in vitro, in a new chromosomal breakage disorder, the nijmegen breakage syndrome
-
RD Taalman, NG Jaspers, JM Scheres, J de Wit, TW Hustinx. Hypersensitivity to ionizing radiation, in vitro, in a new chromosomal breakage disorder, the Nijmegen breakage syndrome. Mutat Res 112:23-32, 1983.
-
(1983)
Mutat Res
, vol.112
, pp. 23-32
-
-
Taalman, R.1
Jaspers, J.M.2
Scheres, J.3
De Wit Hustinx, T.W.4
-
46
-
-
0024313378
-
Radioresistant dna synthesis and human genetic diseases
-
BR Young, RB Painter. Radioresistant DNA synthesis and human genetic diseases. Hum Genet 82:113-117, 1989.
-
(1989)
Hum Genet
, vol.82
, pp. 113-117
-
-
Young, B.R.1
Painter, R.B.2
-
47
-
-
0033544724
-
The dna double-strand break repair gene hmre11 is mutated in individuals with an ataxia-telangiectasia-like disorder
-
GS Stewart, RS Maser, T Stankovic, DA Bressan, MI Kaplan, NG Jaspers, A Raams, PJ Byrd, JH Petrini, AM Taylor. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell 99:577-587, 1999.
-
(1999)
Cell
, vol.99
, pp. 577-587
-
-
Stewart, G.1
Maser, T.2
Stankovic, D.A.3
Bressan, M.I.4
Kaplan, N.G.5
Jaspers, A.6
Raams, P.J.7
Byrd, J.H.8
Petrini Taylor, A.M.9
-
48
-
-
0028800878
-
A gene that regulates dna replication in response to dna damage is located on human chromosome 4q
-
GW Verhaegh, W Jongmans, NG Jaspers, AT Natarajan, M Oshimura, PH Lohman, MZ Zdzienicka. A gene that regulates DNA replication in response to DNA damage is located on human chromosome 4q. Am J Hum Genet 57:1095-1103, 1995.
-
(1995)
Am J Hum Genet
, vol.57
, pp. 1095-1103
-
-
Verhaegh, G.W.W.1
Jongmans, N.G.2
Jaspers, A.T.3
Natarajan, M.4
Oshimura, P.H.5
Lohman Zdzienicka, M.Z.6
-
49
-
-
0028810807
-
Characterization of the signal transduction pathway mediating gamma ray-induced inhibition of dna synthesis in human cells: Indirect evidence for involvement of calmodulin but not protein kinase c nor p53
-
R Mirzayans, KS Famulski, L Enns, M Fraser, MC Paterson. Characterization of the signal transduction pathway mediating gamma ray-induced inhibition of DNA synthesis in human cells: indirect evidence for involvement of calmodulin but not protein kinase C nor p53. Oncogene 11:1597-1605, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 1597-1605
-
-
Mirzayans, R.K.1
Famulski, L.2
Enns, M.3
FraserPaterson, M.C.4
-
50
-
-
0034159932
-
The catalytic subunit dna-dependent protein kinase (dna-pkcs) facilitates recovery from radiation-induced inhibition of dna replication
-
J Guan, S DiBiase, G Iliakis. The catalytic subunit DNA-dependent protein kinase (DNA-PKcs) facilitates recovery from radiation-induced inhibition of DNA replication. Nucleic Acids Res 28:1183-1192, 2000.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 1183-1192
-
-
Guan, J.S.1
Dibiase Iliakis, G.2
-
51
-
-
0033619754
-
Expression of full-length nbs1 protein restores normal radiation responses in cells from nijmegen breakage syndrome patients
-
A Ito, H Tauchi, J Kobayashi, K Morishima, A Nakamura, Y Hirokawa, S Matsuura, K Ito, K Komatsu. Expression of full-length NBS1 protein restores normal radiation responses in cells from Nijmegen breakage syndrome patients. Biochem Biophys Res Commun 265:716-721, 1999.
-
(1999)
Biochem Biophys Res CoMmUn
, vol.265
, pp. 716-721
-
-
Ito, A.H.1
Tauchi, J.2
Kobayashi, K.3
Morishima, A.4
Nakamura, Y.5
Hirokawa, S.6
Matsuura, K.7
Ito Komatsu, K.8
-
52
-
-
0031028857
-
Chromosomal sensitivity to clastogenic agents and cell cycle perturbations in nijmegen breakage syndrome lymphoblastoid cell lines
-
A Antoccia, R Ricordy, P Maraschio, S Prudente, C Tanzarella. Chromosomal sensitivity to clastogenic agents and cell cycle perturbations in Nijmegen breakage syndrome lymphoblastoid cell lines. Int J Radiat Biol 71:41-49, 1997.
-
(1997)
Int J Radiat Biol
, vol.71
, pp. 41-49
-
-
Antoccia, A.R.1
Ricordy, P.2
Maraschio, S.3
Prudente Tanzarella, C.4
-
53
-
-
0016786321
-
Ataxia telangiectasia: A human mutation with abnormal radiation sensitivity
-
AM Taylor, DG Harnden, CF Arlett, SA Harcourt, AR Lehmann, S Stevens, BA Bridges. Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 258:427-429, 1975.
-
(1975)
Nature
, vol.258
, pp. 427-429
-
-
Taylor, A.1
Harnden, C.F.2
Arlett, S.A.3
Harcourt, A.R.4
Lehmann, S.5
Stevens Bridges, B.A.6
-
54
-
-
0035085624
-
Normal v(d)j recombination in cells from patients with nijmegen breakage syndrome
-
E Harfst, S Cooper, S Neubauer, L Distel, U Grawunder. Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome. Mol Immunol 37:915-929, 2000.
-
(2000)
Mol Immunol
, vol.37
, pp. 915-929
-
-
Harfst, E.S.1
Cooper, S.2
Neubauer, L.3
Distel Grawunder, U.4
-
55
-
-
0019959755
-
Dna double strand breaks in ehrlich ascites tumor cells at low doses of x-rays. Ii. Can cell death be attributed to double strand breaks?
-
D Blöcher, W Pohlit. DNA double strand breaks in Ehrlich ascites tumor cells at low doses of x-rays. II. Can cell death be attributed to double strand breaks? Int J Radiat Biol Relat Stud Phys Chem Med 42:329-338, 1982.
-
(1982)
Int J Radiat Biol Relat Stud Phys Chem Med
, vol.42
, pp. 329-338
-
-
Blöcher, D.1
Pohlit, W.2
-
56
-
-
0032404350
-
Splitting the atm: Distinct repair and checkpoint defects in ataxia-telangiectasia
-
PA Jeggo, AM Carr, AR Lehmann. Splitting the ATM: Distinct repair and checkpoint defects in ataxia-telangiectasia. Trends Genet 14:312-316, 1998.
-
(1998)
Trends Genet
, vol.14
, pp. 312-316
-
-
Jeggo, P.1
Carr Lehmann, A.R.2
-
57
-
-
0035804778
-
Complementation of chromosomal aberrations in at/nbs hybrids: Inadequacy of rds as an endpoint in complementation studies with immortal nbs cells
-
M Kraakman-van der Zwet, WJI Overkamp, NGJ Jaspers, AT Natarajan, PHM Lohmann, MZ Zdzienicka. Complementation of chromosomal aberrations in AT/NBS hybrids: inadequacy of RDS as an endpoint in complementation studies with immortal NBS cells. Mutat Res 485:177-185, 2001.
-
(2001)
Mutat Res
, vol.485
, pp. 177-185
-
-
Kraakman-Van Der Zwet, M.1
Overkamp, W.J.I.2
Jaspers, N.G.J.3
Natarajan, A.T.4
Lohmann, P.H.M.5
Zdzienicka, M.Z.6
-
58
-
-
0035691835
-
Tel1 from s.Cerevisiae suppresses chromosome aberrations induced by ionizing radiation in ataxia-telangiectasia cells without affecting cell cycle checkpoints
-
JP Cao, MS Meyn, F Eckardt-Schupp, E Fritz. TEL1 from S.cerevisiae suppresses chromosome aberrations induced by ionizing radiation in ataxia-telangiectasia cells without affecting cell cycle checkpoints. Radiat Environ Biophys 40:309-315, 2001.
-
(2001)
Radiat Environ Biophys
, vol.40
, pp. 309-315
-
-
Cao, J.1
Meyn, F.2
Eckardt-Schupp Fritz, E.3
-
59
-
-
16944366639
-
The gene for the ataxia-telangiectasia variant, nijmegen breakage syndrome, maps to a 1-cm interval on chromosome 8q21
-
K Saar, KH Chrzanowska, M Stumm, M Jung, G Nurnberg, TF Wienker, E See-manova, RD Wegner, A Reis, K Sperling. The gene for the ataxia-telangiectasia variant, Nijmegen breakage syndrome, maps to a 1-cM interval on chromosome 8q21. Am J Hum Genet 60:605-610, 1997.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 605-610
-
-
Saar, K.1
Chrzanowska, K.H.2
Stumm, M.3
Jung, M.4
Nurnberg, G.5
Wienker, T.F.6
See-Manova, E.7
Wegner, R.D.8
Reis, A.9
Sperling, K.10
-
60
-
-
16944367119
-
Genetic mapping using microcell-mediated chromosome transfer suggests a locus for nijmegen breakage syndrome at chromosome 8q21-24
-
S Matsuura, C Weemaes, D Smeets, H Takami, N Kondo, S Sakamoto, N Yano, A Nakamura, H Tauchi, S Endo, M Oshimura, K Komatsu. Genetic mapping using microcell-mediated chromosome transfer suggests a locus for Nijmegen breakage syndrome at chromosome 8q21-24. Am J Hum Genet 60:1487-1494, 1997.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 1487-1494
-
-
Matsuura, S.C.1
Weemaes, D.2
Smeets, H.3
Takami, N.4
Kondo, S.5
Sakamoto, N.6
Yano, A.7
Nakamura, H.8
Tauchi, S.9
Endo, M.10
Oshimura Komatsu, K.11
-
61
-
-
0032076190
-
Nib-rin, a novel dna double-strand break repair protein, is mutated in nijmegen breakage syndrome
-
R Varon, C Vissinga, M Platzer, KM Cerosaletti, KH Chrzanowska, K Saar, G Beckmann, E Seemanova, PR Cooper, NJ Nowak, M Stumm, CM Weemaes, RA Gatti, RK Wilson, M Digweed, A Rosenthal, K Sperling, P Concannon, A Reis. Nib-rin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell 93:467-476, 1998.
-
(1998)
Cell
, vol.93
, pp. 467-476
-
-
Varon, R.C.1
Vissinga, M.2
Platzer, K.M.3
Cerosaletti, K.H.4
Chrzanowska, K.5
Saar, G.6
Beckmann, E.7
Seemanova, P.R.8
Cooper, N.J.9
Nowak, M.10
Stumm, C.M.11
Weemaes, R.A.12
Gatti, R.K.13
Wilson, M.14
Digweed, A.15
Rosenthal, K.16
Sperling, P.17
Concannon Reis, A.18
-
62
-
-
17344372572
-
Positional cloning of the gene for nijmegen breakage syndrome
-
S Matsuura, H Tauchi, A Nakamura, N Kondo, S Sakamoto, S Endo, D Smeets, B Solder, BH Belohradsky, VM Der Kaloustian, M Oshimura, M Isomura, Y Nakamura, K Komatsu. Positional cloning of the gene for Nijmegen breakage syndrome. Nat Genet 19:179-181, 1998.
-
(1998)
Nat Genet
, vol.19
, pp. 179-181
-
-
Matsuura, S.H.1
Tauchi, A.2
Nakamura, N.3
Kondo, S.4
Sakamoto, S.5
Endo, D.6
Smeets, B.7
Solder, B.H.8
Belohradsky, V.M.9
Der Kaloustian, M.10
Oshimura, M.11
Isomura, Y.12
Nakamura Komatsu, K.13
-
63
-
-
0038978266
-
Positional cloning and functional analysis of the gene responsible for nijmegen breakage syndrome, nbs1
-
H Tauchi. Positional cloning and functional analysis of the gene responsible for Nijmegen breakage syndrome, NBS1. J Radiat Res 41:9-17, 2000.
-
(2000)
J Radiat Res
, vol.41
, pp. 9-17
-
-
Tauchi, H.1
-
64
-
-
0032076248
-
The hmre11/hrad50 protein complex and nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular dna damage response
-
JP Carney, RS Maser, H Olivares, EM Davis, M Le Beau, JRr Yates, L Hays, WF Morgan, JH Petrini. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell 93:477-486, 1998.
-
(1998)
Cell
, vol.93
, pp. 477-486
-
-
Carney, J.1
Maser, H.2
Olivares, E.M.3
Davis Le Beau, M.4
JRr, Y.5
Hays, L.6
Morgan, W.F.7
Petrini, J.H.8
-
65
-
-
0029095108
-
Weaver. Isolation and characterization of the human mre11 homologue
-
JH Petrini, ME Walsh, C DiMare, XN Chen, JR Korenberg, DT Weaver. Isolation and characterization of the human MRE11 homologue. Genomics 29:80-86, 1995.
-
(1995)
Genomics
, vol.29
, pp. 80-86
-
-
Petrini, J.1
Walsh, C.2
DiMare, X.N.3
Chen JR, D.T.4
-
66
-
-
0029742576
-
Human rad50 is physically associated with human mre11. Identification of a conserved multiprotein complex implicated in recombinational dna repair
-
GM Dolganov, RS Maser, A Novikov, L Tosto, S Chong, DA Bressan, JH Petrini. Human Rad50 is physically associated with human Mre11. Identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol Cell Biol 16:4832-4841, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4832-4841
-
-
Dolganov, G.1
Maser, A.2
Novikov, L.3
Tosto, S.4
Chong, D.A.5
Bressan Petrini, J.H.6
-
67
-
-
0030764691
-
Hmre11 and hrad50 nuclear foci are induced during the normal cellular response to dna double-strand breaks
-
RS Maser, KJ Monsen, BE Nelms, JH Petrini. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol Cell Biol 17:6087-6096, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6087-6096
-
-
Maser, R.1
Monsen Nelms, B.E.2
Petrini, J.H.3
-
68
-
-
0034066847
-
Retroviral expression of the nbs1 gene in cultured nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation
-
KM Cerosaletti, A Desai-Mehta, TC Yeo, M Kraakman-Van Der Zwet, MZ Zdzienicka, P Concannon. Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation. Mutagenesis 15:281-286, 2000.
-
(2000)
Mutagenesis
, vol.15
, pp. 281-286
-
-
Cerosaletti, K.M.A.1
Desai-Mehta, T.C.2
Yeo Kraakman-Van Der Zwet, M.3
Zdzienicka, M.Z.4
Concannon, P.5
-
69
-
-
0033180301
-
Nijmegen breakage syndrome: Consequences of defective dna double strand break repair
-
M Digweed, A Reis, K Sperling. Nijmegen breakage syndrome: consequences of defective DNA double strand break repair. Bioessays 21:649-656, 1999.
-
(1999)
Bioessays
, vol.21
, pp. 649-656
-
-
Digweed, M.A.1
Reis Sperling, K.2
-
70
-
-
0035068565
-
An alternative mode of translation permits production of a variant nbs1 protein from the common nijmegen breakage syndrome allele
-
RS Maser, R Zinkel, JH Petrini. An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele. Nat Genet 27:417-421, 2001.
-
(2001)
Nat Genet
, vol.27
, pp. 417-421
-
-
Maser, R.S.R.1
Zinkel Petrini, J.H.2
-
71
-
-
0035936554
-
Targeted disruption of the nijmegen breakage syndrome gene nbs1 leads to early embryonic lethality in mice
-
J Zhu, S Petersen, L Tessarollo, A Nussenzweig. Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice. Curr Biol 11:105-109, 2001.
-
(2001)
Curr Biol
, vol.11
, pp. 105-109
-
-
Zhu, J.S.1
Petersen, L.2
Tessarollo Nussenzweig, A.3
-
72
-
-
0030749867
-
Conditional gene targeted deletion by cre recombinase demonstrates the requirement for the double-strand break repair mre11 protein in murine embryonic stem cells
-
Y Xiao, DT Weaver. Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. Nucleic Acids Res 25:2985-2991, 1997.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2985-2991
-
-
Xiao, Y.1
Weaver, D.T.2
-
73
-
-
0033485758
-
Mre11 is essential for the maintenance of chromosomal dna in vertebrate cells
-
Y Yamaguchi-Iwai, E Sonoda, MS Sasaki, C Morrison, T Haraguchi, Y Hiraoka, YM Yamashita, T Yagi, M Takata, C Price, N Kakazu, S Takeda. Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells. EMBO J 18, 6619-6629, 1999.
-
(1999)
EMBO J
, vol.18
, pp. 6619-6629
-
-
Yamaguchi-Iwai, Y.E.1
Sonoda, M.S.2
Sasaki, C.3
Morrison, T.4
Haraguchi, Y.5
Hiraoka, Y.M.6
Yamashita, T.7
Yagi, M.8
Takata, C.9
Price, N.10
Kakazu Takeda, S.11
-
74
-
-
0033594904
-
Disruption of mrad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
-
G Luo, MS Yao, CF Bender, M Mills, AR Bladl, A Bradley, JH Petrini. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proc Natl Acad Sci USA 96:7376-7381, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7376-7381
-
-
Luo, G.1
Yao, M.S.2
Bender, C.F.3
Mills, M.4
Bladl, A.R.5
Bradley, A.6
Petrini, J.H.7
-
75
-
-
0034597354
-
Japanese family with an autosomal dominant chromosome instability syndrome. a new neurodegenerative disease
-
S Ishikawa, M Ishikawa, T Tokuda, K Yoshida, K Wakui, S Matsuura, S Ohara, Y Sekijima, E Hidaka, Y Fukushima, H Shigeta, K Komatsu, S Ikeda. Japanese family with an autosomal dominant chromosome instability syndrome. A new neurodegenerative disease? Am J Med Genet 94:265-270, 2000.
-
(2000)
Am J Med Genet
, vol.94
, pp. 265-270
-
-
Ishikawa, S.M.1
Ishikawa, T.2
Tokuda, K.3
Yoshida, K.4
Wakui, S.5
Matsuura, S.6
Ohara, Y.7
Sekijima, E.8
Hidaka, Y.9
Fukushima, H.10
Shigeta, K.11
Komatsu Ikeda, S.12
-
76
-
-
0035871931
-
Combined immunodeficiency, chromosomal instability, and postnatal growth deficiency in a japanese girl
-
M Yamada, S Matsuura, M Tsukahara, K Ebe, M Ohtsu, H Furata, I Kobayashi, N Kawamura, M Okano, R Shouji, K Kobayashi. Combined immunodeficiency, chromosomal instability, and postnatal growth deficiency in a Japanese girl. Am J Med Genet 100:9-12, 2001.
-
(2001)
Am J Med Genet
, vol.100
, pp. 9-12
-
-
Yamada, M.S.1
Matsuura, M.2
Tsukahara, K.3
Ebe, M.4
Ohtsu, H.5
Furata, I.6
Kobayashi, N.7
Kawamura, M.8
Okano, R.9
Shouji Kobayashi, K.10
-
77
-
-
0035374871
-
Nijmegen breakage syndrome in a dutch patient not resulting in a defect in nbs1
-
JA Hiel, CM Weemaes, BG van Engelen, D Smeets, M Ligtenberg, I van der Burgt, LP van den Heuvel, KM Cerosaletti, FJ Gabreels, P Concannon. Nijmegen breakage syndrome in a Dutch patient not resulting in a defect in NBS1. J Med Genet 38:E19, 2001.
-
(2001)
J Med Genet
, vol.38
, pp. E19
-
-
Hiel, J.1
Weemaes, B.G.2
Van Engelen, D.3
Smeets, M.4
Ligtenberg, I.5
Van Der Burgt, L.P.6
Van Den Heuvel, K.M.7
Cerosaletti, F.J.8
Gabreels Concannon, P.9
-
78
-
-
0033563229
-
Nbs1 potentiates atp-driven dna unwinding and endonuclease cleavage by the mre11/rad50 complex
-
TT Paull, M Gellert. Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev 13:1276-1288, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 1276-1288
-
-
Paull, T.T.1
Gellert, M.2
-
79
-
-
0034106722
-
Atm-dependent phosphorylation of nibrin in response to radiation exposure
-
M Gatei, D Young, KM Cerosaletti, A Desai-Mehta, K Spring, S Kozlov, MF Lavin, RA Gatti, P Concannon, K Khanna. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat Genet 25:115-119, 2000.
-
(2000)
Nat Genet
, vol.25
, pp. 115-119
-
-
Gatei, M.D.1
Young, K.M.2
Cerosaletti, A.3
Desai-Mehta, K.4
Spring, S.5
Kozlov, M.F.6
Lavin, R.A.7
Gatti, P.8
Concannon Khanna, K.9
-
80
-
-
0034611728
-
Atm phospho-rylates p95/nbs1 in an s-phase checkpoint pathway
-
DS Lim, ST Kim, B Xu, RS Maser, J Lin, JH Petrini, MB Kastan. ATM phospho-rylates p95/nbs1 in an S-phase checkpoint pathway. Nature 404:613-617, 2000.
-
(2000)
Nature
, vol.404
, pp. 613-617
-
-
Lim, D.S.1
Lim, S.T.2
Xu, B.3
Maser, R.S.4
Lin, J.H.5
Petrini, J.H.6
Kastan, M.B.7
-
81
-
-
0034713393
-
Functional link between ataxia-telangiectasia and nijmegen breakage syndrome gene products
-
S Zhao, YC Weng, SS Yuan, YT Lin, HC Hsu, SC Lin, E Gerbino, MH Song, MZ Zdzienicka, RA Gatti, JW Shay, Y Ziv, Y Shiloh, EY Lee. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature 405:473-477, 2000.
-
(2000)
Nature
, vol.405
, pp. 473-477
-
-
Zhao, S.Y.1
Weng, S.S.2
Yuan, Y.T.3
Lin, H.C.4
Hsu, S.C.5
Lin, E.6
Gerbino, M.H.7
Song, M.Z.8
Zdzienicka, R.A.9
Gatti, J.W.10
Shay, Y.11
Ziv, Y.12
Shiloh Lee, E.Y.13
-
82
-
-
0034713466
-
Atm phosphorylation of nijmegen breakage syndrome protein is required in a dna damage response
-
X Wu, V Ranganathan, DS Weisman, WF Heine, DN Ciccone, TB O’Neill, KE Crick, KA Pierce, WS Lane, G Rathbun, DM Livingston, DT Weaver. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature 405:477-482, 2000.
-
(2000)
Nature
, vol.405
, pp. 477-482
-
-
Wu, X.V.1
Ranganathan, D.S.2
Weisman, W.F.3
Heine, D.N.4
Ciccone, T.B.5
O’Neill, K.E.6
Crick, K.A.7
Pierce, W.S.8
Lane, G.9
Rathbun, D.M.10
Livingston Weaver, D.T.11
-
83
-
-
0033538496
-
The nijmegen breakage syndrome protein is essential for mre11 phosphorylation upon dna damage
-
Z Dong, Q Zhong, PL Chen. The Nijmegen breakage syndrome protein is essential for Mre11 phosphorylation upon DNA damage. J Biol Chem 274:19513-19516, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 19513-19516
-
-
Dong, Z.Q.1
Zhong Chen, P.L.2
-
84
-
-
0033384423
-
Identification, characterization, and mapping of a mouse homolog of the gene mutated in nijmegen breakage syndrome
-
CS Vissinga, TC Yeo, J Woessner, HF Massa, RK Wilson, BJ Trask, P Concannon. Identification, characterization, and mapping of a mouse homolog of the gene mutated in Nijmegen breakage syndrome. Cytogenet Cell Genet 87:80-84, 1999.
-
(1999)
Cytogenet Cell Genet
, vol.87
, pp. 80-84
-
-
Vissinga, C.1
Yeo, J.2
Woessner, H.F.3
Massa, R.K.4
Wilson, B.J.5
Trask Concannon, P.6
-
85
-
-
0033852325
-
Expression pattern of the nijmegen breakage syndrome gene, nbs1, during murine development
-
M Wilda, I Demuth, P Concannon, K Sperling, H Hameister. Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development. Hum Mol Genet 9:1739-1744, 2000.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1739-1744
-
-
Wilda, M.I.1
Demuth, P.2
Concannon, K.3
Sperling Hameister, H.4
-
86
-
-
0026029613
-
The recombination activating gene-1 (rag-1) transcript is present in the murine central nervous system
-
JJ Chun, DG Schatz, MA Oettinger, R Jaenisch, D Baltimore. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell 64:189-200, 1991.
-
(1991)
Cell
, vol.64
, pp. 189-200
-
-
Chun, J.1
Schatz, M.A.2
Oettinger, R.3
Jaenisch Baltimore, D.4
-
87
-
-
0033587098
-
Anderson. Dna-pk, the dna-activated protein kinase, is differentially expressed in normal and malignant human tissues
-
U Moll, R Lau, MA Sypes, MM Gupta, CW Anderson. DNA-PK, the DNA-activated protein kinase, is differentially expressed in normal and malignant human tissues. Oncogene 18:3114-3126, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 3114-3126
-
-
U Moll, R.1
Lau, M.A.2
Sypes, M.M.3
Gupta, C.W.4
-
88
-
-
0035808385
-
The forkhead-associated domain of nbs1 is essential for nuclear foci formation after irradiation but not essential for hrad50-hmre11-nbs1 complex dna repair activity
-
H Tauchi, J Kobayashi, K Morishima, S Matsuura, A Nakamura, T Shiraishi, E Ito, D Masnada, D Delia, K Komatsu. The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50-hMRE11-NBS1 complex DNA repair activity. J Biol Chem 276:12-15, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 12-15
-
-
Tauchi, H.J.1
Kobayashi, K.2
Morishima, S.3
Matsuura, A.4
Nakamura, T.5
Shiraishi, E.6
Ito, D.7
Masnada, D.8
Delia Komatsu, K.9
-
89
-
-
0028819384
-
Multiple pathways for homologous recombination in saccharomyces cerevisiae
-
AJ Rattray, LS Symington. Multiple pathways for homologous recombination in Saccharomyces cerevisiae. Genetics 139:45-56, 1995.
-
(1995)
Genetics
, vol.139
, pp. 45-56
-
-
Rattray, A.J.1
Symington, L.S.2
-
90
-
-
0028943378
-
Functions of the yeast meiotic recombination genes, mre11 and mre2
-
H Ogawa, K Johzuka, T Nakagawa, SH Leem, AH Hagihara. Functions of the yeast meiotic recombination genes, MRE11 and MRE2. Adv Biophys 31:67-76, 1995.
-
(1995)
Adv Biophys
, vol.31
, pp. 67-76
-
-
Ogawa, H.K.1
Johzuka, T.2
Nakagawa, S.H.3
Leem Hagihara, A.H.4
-
91
-
-
0030070982
-
Meiotic recombination initiated by a double-strand break in rad50 delta yeast cells otherwise unable to initiate meiotic recombination
-
A Malkova, L Ross, D Dawson, MF Hoekstra, JE Haber. Meiotic recombination initiated by a double-strand break in rad50 delta yeast cells otherwise unable to initiate meiotic recombination. Genetics 143:741-754, 1996.
-
(1996)
Genetics
, vol.143
, pp. 741-754
-
-
Malkova, A.L.1
Ross, D.2
Dawson, M.F.3
Hoekstra Haber, J.E.4
-
92
-
-
0028789631
-
Covalent protein-dna complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast
-
S Keeney, N Kleckner. Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast. Proc Natl Acad Sci USA 92:11274-11278, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11274-11278
-
-
Keeney, S.1
Kleckner, N.2
-
93
-
-
0032721091
-
The mre11-rad50-xrs2 protein complex facilitates homologous recombination-based double-strand break repair in saccharomyces cerevisiae
-
DA Bressan, BK Baxter, JH Petrini. The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol 19:7681-7687, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7681-7687
-
-
Bressan, D.1
Baxter Petrini, J.H.2
-
94
-
-
0034107667
-
Long palindromic sequences induce double-strand breaks during meiosis in yeast
-
F Nasar, C Jankowski, DK Nag. Long palindromic sequences induce double-strand breaks during meiosis in yeast. Mol Cell Biol 20:3449-3458, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3449-3458
-
-
Nasar, F.C.1
Jankowski Nag, D.K.2
-
95
-
-
0034733599
-
Recombination factors of saccharomyces cerevisiae
-
P Sung, KM Trujillo, S Van Komen. Recombination factors of Saccharomyces cerevisiae. Mutat Res 451:257-275, 2000.
-
(2000)
Mutat Res
, vol.451
, pp. 257-275
-
-
Sung, P.K.1
Trujillo Van Komen, S.2
-
96
-
-
0028246091
-
Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in saccharomyces cerevisiae
-
RH Schiestl, J Zhu, TD Petes. Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol 14:4493-4500, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4493-4500
-
-
Schiestl, R.H.J.1
Zhu Petes, T.D.2
-
97
-
-
0029976325
-
Cell cycle and genetic requirements of two pathways of non-homologous end-joining repair of double-strand breaks in saccharomyces cerevisiae
-
JK Moore, JE Haber. Cell cycle and genetic requirements of two pathways of non-homologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol 16:2164-2173, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2164-2173
-
-
Moore, J.K.1
Haber, J.E.2
-
98
-
-
0030031522
-
Effects of mutations of rad50, rad51, rad52, and related genes on illegitimate recombination in saccharomyces cerevisiae
-
Y Tsukamoto, J Kato, H Ikeda. Effects of mutations of RAD50, RAD51, RAD52, and related genes on illegitimate recombination in Saccharomyces cerevisiae. Genetics 142:383-391, 1996.
-
(1996)
Genetics
, vol.142
, pp. 383-391
-
-
Tsukamoto, Y.J.1
Kato Ikeda, H.2
-
99
-
-
0030849085
-
Identification of saccharomyces cerevisiae dna ligase iv. Involvement in dna double-strand break repair
-
SH Teo, SP Jackson. Identification of Saccharomyces cerevisiae DNA ligase IV. Involvement in DNA double-strand break repair. EMBO J 16:4788-4795, 1997.
-
(1997)
EMBO J
, vol.16
, pp. 4788-4795
-
-
Teo, S.H.1
Jackson, S.P.2
-
101
-
-
0344069724
-
Repair of endonuclease-induced double-strand breaks in saccharomyces cerevisiae. essential role for genes associated with nonhomologous end-joining
-
LK Lewis, JW Westmoreland, MA Resnick. Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae. Essential role for genes associated with nonhomologous end-joining. Genetics 152:1513-1529, 1999.
-
(1999)
Genetics
, vol.152
, pp. 1513-1529
-
-
Lewis, L.K.1
Westmoreland, J.W.2
Resnick, M.A.3
-
102
-
-
0032536861
-
Components of the ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
-
SJ Boulton, SP Jackson. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17:1819-1828, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 1819-1828
-
-
Boulton, S.J.1
Jackson, S.P.2
-
103
-
-
0032959506
-
Rad50 and rad51 define two pathways that collaborate to maintain telomeres in the absence of telomerase
-
S Le, JK Moore, JE Haber, CW Greider. RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics 152:143-152, 1999.
-
(1999)
Genetics
, vol.152
, pp. 143-152
-
-
Le, S.J.1
Moore, J.E.2
Haber Greider, C.W.3
-
104
-
-
0034013797
-
The mre11p/rad50p/xrs2p complex and the tel1p function in a single pathway for telomere maintenance in yeast
-
KB Ritchie, TD Petes. The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics 155:475-479, 2000.
-
(2000)
Genetics
, vol.155
, pp. 475-479
-
-
Ritchie, K.B.1
Petes, T.D.2
-
105
-
-
0032493889
-
Saccharomyces ku70, mre11/rad50 and rpa proteins regulate adaptation to g2/m arrest after dna damage
-
SE Lee, JK Moore, A Holmes, K Umezu, RD Kolodner, JE Haber. Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94:399-409, 1998.
-
(1998)
Cell
, vol.94
, pp. 399-409
-
-
Lee, S.1
Moore, A.2
Holmes, K.3
Umezu, R.D.4
Kolodner Haber, J.E.5
-
106
-
-
0033590179
-
Dna damage-induced cell cycle checkpoints and dna strand break repair in development and tumorige-nesis
-
GK Dasika, SC Lin, S Zhao, P Sung, A Tomkinson, EY Lee. DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorige-nesis. Oncogene 18:7883-7899, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 7883-7899
-
-
Dasika, G.1
Lin, S.2
Zhao, P.3
Sung, A.4
Tomkinson Lee, E.Y.5
-
107
-
-
0026759693
-
Xrs2, a dna repair gene of saccharomyces cerevisiae, is needed for meiotic recombination
-
EL Ivanov, VG Korolev, F Fabre. XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics 132:651-664, 1992.
-
(1992)
Genetics
, vol.132
, pp. 651-664
-
-
Ivanov, E.1
Korolev Fabre, F.2
-
108
-
-
0032860479
-
Gross chromosomal rearrangements in saccharomyces cerevisiae replication and recombination defective mutants
-
C Chen, RD Kolodner. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet 23:81-85, 1999.
-
(1999)
Nat Genet
, vol.23
, pp. 81-85
-
-
Chen, C.1
Kolodner, R.D.2
-
109
-
-
0030000946
-
Genetic requirements for the single-strand annealing pathway of double-strand break repair in saccharomyces cerevisiae
-
EL Ivanov, N Sugawara, J Fishman-Lobell, JE Haber. Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics 142:693-704, 1996.
-
(1996)
Genetics
, vol.142
, pp. 693-704
-
-
Ivanov, E.L.N.1
Sugawara, J.2
Fishman-Lobell Haber, J.E.3
-
110
-
-
0032567108
-
Complex formation and functional versatility of mre11 of budding yeast in recombination
-
T Usui, T Ohta, H Oshiumi, J Tomizawa, H Ogawa, T Ogawa. Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell 95:705-716, 1998.
-
(1998)
Cell
, vol.95
, pp. 705-716
-
-
Usui, T.T.1
Ohta, H.2
Oshiumi, J.3
Tomizawa, H.4
Ogawa Ogawa, T.5
-
111
-
-
0034610290
-
Protein kinase activity of tel1p and mec1p, two saccharomyces cerevisiae proteins related to the human atm protein kinase
-
JC Mallory, TD Petes. Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc Natl Acad Sci USA 97:13749-13754, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13749-13754
-
-
Mallory, J.C.1
Petes, T.D.2
-
112
-
-
0029088371
-
Tel1, a gene involved in controlling telomere length in s. Cerevisiae, is homologous to the human ataxia telangiectasia gene
-
PW Greenwell, SL Kronmal, SE Porter, J Gassenhuber, B Obermaier, TD Petes. TEL1, a gene involved in controlling telomere length in S. Cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82:823-829, 1995.
-
(1995)
Cell
, vol.82
, pp. 823-829
-
-
Greenwell, P.1
Kronmal, S.E.2
Porter, J.3
Gassenhuber, B.4
Obermaier Petes, T.D.5
-
113
-
-
0029150855
-
Tel1, an s. Cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene mec1
-
DM Morrow, DA Tagle, Y Shiloh, FS Collins, P Hieter. TEL1, an S. Cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82:831-840, 1995.
-
(1995)
Cell
, vol.82
, pp. 831-840
-
-
Morrow, D.1
Tagle, Y.2
Shiloh, F.S.3
Collins Hieter, P.4
-
114
-
-
0033836516
-
The yeast tel1 gene partially substitutes for human atm in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in a-t cells
-
E Fritz, AA Friedl, RM Zwacka, F Eckardt-Schupp, MS Meyn. The yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells. Mol Biol Cell 11:2605-2616, 2000.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 2605-2616
-
-
Fritz, E.A.1
Friedl, R.M.2
Zwacka, F.3
Eckardt-Schupp Meyn, M.S.4
-
115
-
-
0034892653
-
Mre11 protein complex prevents double-strand break accumulation during chromosomal dna replication
-
V Costanzo, K Robertson, M Bibikova, E Kim, D Grieco, M Gottesman, D Carroll, J Gautier. Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication. Mol Cell 8:137-147, 2001.
-
(2001)
Mol Cell
, vol.8
, pp. 137-147
-
-
Costanzo, V.K.1
Robertson, M.2
Bibikova, E.3
Kim, D.4
Grieco, M.5
Gottesman, D.6
Carroll Gautier, J.7
-
116
-
-
0032555480
-
Nuclease activities in a complex of human recombination and dna repair factors rad50, mre11, and p95
-
KM Trujillo, SS Yuan, EY Lee, P Sung. Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J Biol Chem 273:21447-21450, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 21447-21450
-
-
Trujillo, K.1
Yuan, E.Y.2
Lee Sung, P.3
-
117
-
-
0024669753
-
The yeast rad50 gene encodes a predicted 153-kd protein containing a purine nucleotide-binding domain and two large heptad-re-peat regions
-
E Alani, S Subbiah, N Kleckner. The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-re-peat regions. Genetics 122:47-57, 1989.
-
(1989)
Genetics
, vol.122
, pp. 47-57
-
-
Alani, E.S.1
Subbiah Kleckner, N.2
-
118
-
-
0032085295
-
The 3' to 5' exonuclease activity of mre 11 facilitates repair of dna double-strand breaks
-
TT Paull, M Gellert. The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol Cell 1:969-979, 1998.
-
(1998)
Mol Cell
, vol.1
, pp. 969-979
-
-
Paull, T.T.1
Gellert, M.2
-
119
-
-
0032476658
-
Distinct roles of two separable in vitro activities of yeast mre11 in mitotic and meiotic recombination
-
M Furuse, Y Nagase, H Tsubouchi, K Murakami-Murofushi, T Shibata, K Ohta. Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J 17:6412-6425, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 6412-6425
-
-
Furuse, M.Y.1
Nagase, H.2
Tsubouchi, K.3
Murakami-Murofushi, T.4
Shibata Ohta, K.5
-
120
-
-
0032931844
-
The nuclease activity of mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
-
S Moreau, JR Ferguson, LS Symington. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol 19:556-566, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 556-566
-
-
Moreau, S.J.1
Ferguson Symington, L.S.2
-
121
-
-
0032562595
-
In situ visualization of dna double-strand break repair in human fibroblasts
-
BE Nelms, RS Maser, JF MacKay, MG Lagally, JH Petrini. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280:590-592,1998.
-
(1998)
Science
, vol.280
, pp. 590-592
-
-
Nelms, B.1
Maser, J.F.2
MacKay, M.G.3
Lagally Petrini, J.H.4
-
122
-
-
0034997651
-
Distinct functional domains of nib-rin mediate mre11 binding, focus formation, and nuclear localization
-
A Desai-Mehta, KM Cerosaletti, P Concannon. Distinct functional domains of nib-rin mediate Mre11 binding, focus formation, and nuclear localization. Mol Cell Biol 21:2184-2191, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2184-2191
-
-
Desai-Mehta, A.K.1
Cerosaletti Concannon, P.2
-
123
-
-
0031031787
-
From brca1 to rap1: A widespread brct module closely associated with dna repair
-
I Callebaut, JP Mornon. From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Lett 400:25-30,1997.
-
(1997)
FEBS Lett
, vol.400
, pp. 25-30
-
-
Callebaut, I.1
Mornon, J.P.2
-
124
-
-
0034739853
-
P53 binding protein 1 (53bp1) is an early participant in the cellular response to dna double-strand breaks
-
LB Schultz, NH Chehab, A Malikzay, TD Halazonetis. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 151:1381-1390, 2000.
-
(2000)
J Cell Biol
, vol.151
, pp. 1381-1390
-
-
Schultz, L.1
Chehab Halazonetis, A.T.D.2
-
125
-
-
0033618621
-
Association of brca1 with the hrad50-hmre11-p95 complex and the dna damage response
-
Q Zhong, CF Chen, S Li, Y Chen, CC Wang, J Xiao, PL Chen, ZD Sharp, WH Lee. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science 285:747-750, 1999.
-
(1999)
Science
, vol.285
, pp. 747-750
-
-
Zhong, Q.C.1
Chen, S.2
Li, Y.3
Chen, C.C.4
Wang, J.5
Xiao, P.L.6
Chen, Z.D.7
Sharp Lee, W.H.8
-
126
-
-
0034655991
-
Basc, a super complex of brca1-associated proteins involved in the recognition and repair of aberrant dna structures
-
Y Wang, D Cortez, P Yazdi, N Neff, SJ Elledge, J Qin. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 14:927-939, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 927-939
-
-
Wang, Y.D.1
Cortez, P.2
Yazdi, N.3
Neff, S.J.4
Elledge Qin, J.5
-
127
-
-
0035932978
-
Direct dna binding by brca1
-
TT Paull, D Cortez, B Bowers, SJ Elledge, M Gellert. Direct DNA binding by Brca1. Proc Natl Acad Sci USA 98:6086-6091, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6086-6091
-
-
Paull, T.T.D.1
Cortez, B.2
Bowers, S.J.3
Elledge Gellert, M.4
-
128
-
-
0034094425
-
The rag proteins and v(D)j recombination, complexes, ends, and transposition
-
SD Fugmann, AI Lee, PE Shockett, IJ Villey, DG Schatz. The RAG proteins and V(D)J recombination, complexes, ends, and transposition. Annu Rev Immunol 18:495-527, 2000.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 495-527
-
-
Fugmann, S.1
Lee, P.E.2
Shockett, I.J.3
Villey Schatz, D.G.4
-
129
-
-
0032904693
-
The biochemistry and biological significance of nonhomologous dna end joining: An essential repair process in multicellular eukaryotes
-
MR Lieber. The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes. Genes Cells 4:77-85, 1999.
-
(1999)
Genes Cells
, vol.4
, pp. 77-85
-
-
Lieber, M.R.1
-
130
-
-
0034623860
-
Nussenzweig. Response to rag-mediated v(d)j cleavage by nbs1 and gamma-h2ax
-
HT Chen, A Bhandoola, MJ Difilippantonio, J Zhu, MJ Brown, X Tai, EP Rogakou, TM Brotz, WM Bonner, T Ried, A Nussenzweig. Response to RAG-mediated V(D)J cleavage by NBS1 and gamma-H2AX. Science 290:1962-1965, 2000.
-
(2000)
Science
, vol.290
, pp. 1962-1965
-
-
Chen, H.T.A.1
Bhandoola, M.J.2
Difilippantonio, J.3
Zhu, M.J.4
Brown, X.5
Tai, E.P.6
Rogakou, T.M.7
Brotz, W.M.8
Bonner T, A.9
-
131
-
-
0031582059
-
Identification of v(D)j recombination coding end intermediates in normal thymocytes
-
F Livak, DG Schatz. Identification of V(D)J recombination coding end intermediates in normal thymocytes. J Mol Biol 267:1-9, 1997.
-
(1997)
J Mol Biol
, vol.267
, pp. 1-9
-
-
Livak, F.1
Schatz, D.G.2
-
132
-
-
0030964130
-
A stable rag1-rag2-dna complex that is active in v(D)j cleavage
-
K Hiom, M Gellert. A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage. Cell 88:65-72, 1997.
-
(1997)
Cell
, vol.88
, pp. 65-72
-
-
Hiom, K.1
Gellert, M.2
-
133
-
-
0030887862
-
Rag1 and rag2 form a stable postcleavage synaptic complex with dna containing signal ends in v(D)j recombination
-
A Agrawal, DG Schatz. RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination. Cell 89:43-53, 1997.
-
(1997)
Cell
, vol.89
, pp. 43-53
-
-
Agrawal, A.1
Schatz, D.G.2
-
134
-
-
0027953084
-
Normal v(d)j coding junction formation in dna ligase i deficiency syndromes
-
JH Petrini, JW Donovan, C Dimare, DT Weaver. Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes. J Immunol 152:176-183, 1994.
-
(1994)
J Immunol
, vol.152
, pp. 176-183
-
-
Petrini, J.1
Donovan, C.2
Dimare Weaver, D.T.3
-
135
-
-
0032522443
-
The telomerase reverse transcriptase. Components and regulation
-
CI Nugent, V Lundblad. The telomerase reverse transcriptase. Components and regulation. Genes Dev 12:1073-1085, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 1073-1085
-
-
Nugent, C.I.1
Lundblad, V.2
-
136
-
-
0010045614
-
Extension of life-span by introduction of telom-erase into normal human cells
-
AG Bodnar, M Ouellette, M Frolkis, SE Holt, CP Chiu, GB Morin, CB Harley, JW Shay, S Lichtsteiner, WE Wright. Extension of life-span by introduction of telom-erase into normal human cells. Science 279:349-352, 1998.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.M.1
Ouellette, M.2
Frolkis, S.E.3
Holt, C.P.4
Chiu, G.B.5
Morin, C.B.6
Harley, J.W.7
Shay, S.8
Lichtsteiner Wright, W.E.9
-
137
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
TM Bryan, A Englezou, L Dalla-Pozza, MA Dunham, RR Reddel. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3:1271-1274, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.A.1
Englezou, L.2
Dalla-Pozza, M.A.3
Dunham Reddel, R.R.4
-
138
-
-
0029586089
-
A human telomeric protein
-
L Chong, B van Steensel, D Broccoli, H Erdjument-Bromage, J Hanish, P Tempst, T de Lange. A human telomeric protein. Science 270:1663-1667, 1995.
-
(1995)
Science
, vol.270
, pp. 1663-1667
-
-
Chong, L.1
Van Steensel, B.2
Broccoli, D.3
Erdjument-Bromage, H.4
Hanish, J.5
Tempst, P.6
De Lange, T.7
-
139
-
-
84984754548
-
Gilson. Telomeric local ization of trf2, a novel human telobox protein
-
T Bilaud, C Brun, K Ancelin, CE Koering, T Laroche, E Gilson. Telomeric local ization of TRF2, a novel human telobox protein. Nat Genet 17:236-239, 1997.
-
(1997)
Nat Genet
, vol.17
, pp. 236-239
-
-
T Bilaud, C.1
Brun, K.2
Ancelin, C.E.3
Koering, T.4
Laroche, E.5
-
140
-
-
84984775429
-
Human telomeres contain two distinct myb-related proteins, trf1 and trf2
-
D Broccoli, A Smogorzewska, L Chong, T de Lange. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nat Genet 17:231-235, 1997
-
(1997)
Nat Genet
, vol.17
, pp. 231-235
-
-
Broccoli, D.A.1
Smogorzewska, L.2
Chong De Lange, T.3
-
141
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
JD Griffith, L Comeau, S Rosenfield, RM Stansel, A Bianchi, H Moss, T de Lange. Mammalian telomeres end in a large duplex loop. Cell 97:503-514, 1999.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.L.1
Comeau, S.2
Rosenfield, R.M.3
Stansel, A.4
Bianchi, H.5
Moss De Lange, T.6
-
142
-
-
0032167426
-
Telomeres and double-strand breaks: Trying to make ends meet
-
A Bertuch, V Lundblad. Telomeres and double-strand breaks: trying to make ends meet. Trends Cell Biol 8:339-342, 1998.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 339-342
-
-
Bertuch, A.1
Lundblad, V.2
-
143
-
-
0030700397
-
Influence of atm function on telomere metabolism
-
LB Smilenov, SE Morgan, W Mellado, SG Sawant, MB Kastan, TK Pandita. Influence of ATM function on telomere metabolism. Oncogene 15:2659-2665, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 2659-2665
-
-
Smilenov, L.1
Morgan, W.2
Mellado, S.G.3
Sawant, M.B.4
Kastan Pandita, T.K.5
-
145
-
-
0028980925
-
Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells
-
TK Pandita, S Pathak, CR Geard. Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells. Cytogenet Cell Genet 71:86-93, 1995.
-
(1995)
Cytogenet Cell Genet
, vol.71
, pp. 86-93
-
-
Pandita, T.K.S.1
Pathak Geard, C.R.2
-
146
-
-
0029681361
-
Accelerated telomere shortening in ataxia telangiectasia
-
JA Metcalfe, J Parkhill, L Campbell, M Stacey, P Biggs, PJ Byrd, AM Taylor. Accelerated telomere shortening in ataxia telangiectasia. Nat Genet 13:350-353, 1996.
-
(1996)
Nat Genet
, vol.13
, pp. 350-353
-
-
Metcalfe, J.A.J.1
Parkhill, L.2
Campbell, M.3
Stacey, P.4
Biggs, P.J.5
Byrd Taylor, A.M.6
-
147
-
-
0030565541
-
Shmookler-reis. Reduced telomere length in ataxia-telangiectasia fibroblasts
-
SJ Xia, MA Shammas, RJ Shmookler-Reis. Reduced telomere length in ataxia-telangiectasia fibroblasts. Mutat Res 364:1-11, 1996.
-
(1996)
Mutat Res
, vol.364
, pp. 1-11
-
-
Sj Xia, M.A.1
Shammas, R.J.2
-
148
-
-
0034192363
-
Nijmegen breakage syndrome disease protein and mre11 at pml nuclear bodies and meiotic telomeres
-
DB Lombard, L Guarente. Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res 60:2331-2334, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 2331-2334
-
-
Lombard, D.B.1
Guarente, L.2
-
149
-
-
0031881815
-
Mutations in the mre11, rad50, xrs2, and mre2 genes alter chromatin configuration at meiotic dna double-stranded break sites in premeiotic and meiotic cells
-
K Ohta, A Nicolas, M Furuse, A Nabetani, H Ogawa, T Shibata. Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc Natl Acad Sci USA 95:646-651, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 646-651
-
-
Ohta, K.A.1
Nicolas, M.2
Furuse, A.3
Nabetani, H.4
Ogawa Shibata, T.5
-
150
-
-
0342561644
-
Cell-cycle-regulated association of rad50/mre11/nbs1 with trf2 and human telomeres
-
XD Zhu, B Kuster, M Mann, JH Petrini, T de Lange. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet 25:347-352, 2000.
-
(2000)
Nat Genet
, vol.25
, pp. 347-352
-
-
Zhu, X.D.B.1
Kuster, M.2
Mann, J.H.3
Petrini De Lange, T.4
-
151
-
-
0032489012
-
Trf2 protects human telomeres from end-to-end fusions
-
B van Steensel, A Smogorzewska, T de Lange. TRF2 protects human telomeres from end-to-end fusions. Cell 92:401-413, 1998.
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
Van Steensel, B.A.1
Smogorzewska De Lange, T.2
-
152
-
-
0034730633
-
Nbs1 and trf1 colocalize at promyelocytic leukemia bodies during late s/g2 phases in immortalized telomerase-negative cells. Implication of nbs1 in alternative lengthening of telomeres
-
G Wu, WH Lee, PL Chen. NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. J Biol Chem 275:30618-30622, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 30618-30622
-
-
Wu, G.1
Lee, W.H.2
Chen, P.L.3
-
153
-
-
0033199695
-
Telomerase-negative immortalized human cells contain a novel type of promyelo-cytic leukemia (Pml) body
-
TR Yeager, AA Neumann, A Englezou, LI Huschtscha, JR Noble, RR Reddel. Telomerase-negative immortalized human cells contain a novel type of promyelo-cytic leukemia (PML) body. Cancer Res 59:4175-4179, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 4175-4179
-
-
Yeager, T.1
Neumann, A.2
Englezou, L.I.3
Huschtscha, J.R.4
Noble Reddel, R.R.5
-
154
-
-
0024546310
-
Dna, mutationsand ageing
-
TB Kirkwood. DNA, mutations and ageing. Mutat Res 219:1-7, 1989.
-
(1989)
Mutat Res
, vol.219
, pp. 1-7
-
-
TB, K.1
-
155
-
-
0027081044
-
Poly(Adp-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span
-
K Grube, A Bürkle. Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span. Proc Natl Acad Sci USA 89:11759-11763,1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11759-11763
-
-
Grube, K.1
Bürkle, A.2
-
157
-
-
0034669532
-
Wild-derived inbred mouse strains have short telomeres
-
MT Hemann, CW Greider. Wild-derived inbred mouse strains have short telomeres. Nucleic Acids Res 28:4474-4478, 2000.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 4474-4478
-
-
Hemann, M.T.1
Greider, C.W.2
|