RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cerevisiae in response to DNA damage

Genetics

Volumn 145, Issue 1, 1997, Pages 45-62

  Paulovich, A G ^a   Margulies, R U ^a   Garvik, B M ^a   Hartwell, L H ^a  

^a USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA;

ARTICLE; CELL CYCLE S PHASE; DNA ALKYLATION; DNA DAMAGE; DNA REPAIR; MITOSIS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

CELL CYCLE; CELL CYCLE PROTEINS; DNA DAMAGE; DNA, FUNGAL; DNA-BINDING PROTEINS; EPISTASIS, GENETIC; FUNGAL PROTEINS; G1 PHASE; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENES, LETHAL; GENES, SUPPRESSOR; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NUCLEAR PROTEINS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; S PHASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

EID: 0031036995     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. AL-KnoDAlRY, F, and A M CARR, 1992 DMA repair mutants defining G2 checkpoint pathways in Schlwsaccharomyces pombe. EMBO J 11: 1343-1350.
2. ALLEN, J B, Z ZHOU, W SIEDE, E C FRIEDBERG and SJ ELLEDGE, 1994 The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes Dev 8: 2416-2428.
3. AYYAGAKI, R, KJ IMPELLIZZERI, B L YODER, S L GARY and PM j BURGERS, 1995 A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair. Mol Cell Biol 15: 4420-4429.
4. BAUDIN', A, O OZIER-KALOGEROPOUIOS, A DENOUEL, F LACROUTE and C CULLIN, 1993 A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res 21: 3329-3330.
5. BAUER, G A, and P MJ BURGERS, 1990 Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene. Nucleic Acids Res 18: 261-265.
6. BOITEUX, S, O HUISMAM andj LAVAL, 1984 3-Methyladenine residues in DNA induce the SOS function sfiA in Escherichia coli. EMBOJ 3:2569-2573.
7. CAIRNES, J, and C I DAVERN, 1966 Effect of 32P decay upon DNA synthesis by a radiation-sensitive strain of Escherichia coli]. Mol Biol 17: 418-427.
8. CARR, A M, 1995 DNA structure checkpoints in fission yeast. Semin Cell Biol 6: 65-72.
9. CIIEN, J, B DERFLER, A MASKATI and L SAMSON, 1989 Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli. Proc Nad Acad Sei USA 86: 7961-7965.
10. CIIEN, J, B DERFLER and L SAMSON, 1990 Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E coli and is induced in response to DNA alkylation damage. EMBOJ 9: 4569-4575.
11. ENOCH, T, A M CARR and P NURSE, 1992 Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev 6: 2035-2046.
12. FRIEDBERG, E C, G C WALKER and W SIEDE, 1995 DXA Repair and Afutagenesis. ASM Press, Washington, DC.
13. GARVIK, B, M CARSON and L HARTWELL, 1995 Single-stranded DNA arising at telomeres in cdc 13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol Cell Biol 15: 6128-6138.
14. GREENWELL, P W, S L KRONMAL, S E PORTER, J GASSENHUBER, B OBERMAIER et al, 1995 TEL1, a gene involved in controlling telomere length in 5 cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82: 823-829.
15. HARTWELL, L H, 1967 Macromolecule synthesis in temperaturesensitive mutants of yeast. J Bacteriol 93: 1662-1670.
16. HARTWELL, L H, and T A WEINERT, 1989 Checkpoints: controls that ensure the order of cell cycle events. Science 246: 629-634.
17. JONES, J S, and L PRAKASH, 1990 Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers. Yeast 6: 363-366.
18. KADYK, L C, and L H HARWELL, 1993 Replication-dependent sister chromatid recombination in radl mutants of Saccharomyces cerevisiae. Genetics 133: 469-487.
19. LARNER, J M, H LEE andj L HAMLIN, 1994 Radiation effects on DNA synthesis in a defined chromosomal replicon. Mol Cell Biol 14: 1901-1908.
20. Li, R, and A W MURRAY, 1991 Feedback control of mitosis in budding yeast. Cell 66: 519-531.
21. LYDALL, D, and T WEINERT, 1995 Yeast checkpoint genes in DNA damage processing: implications for repair and arrest. Science 270: 1488-1491.
22. LYDALL, D, and T WEINERT, 1996 From DNA damage to cell cycle arrest and suicide: a budding yeast perspective. Curr Opin Genet Dev 6: 4-11.
23. MORRISON, A, R B CHRISTENSEN, J ALLEY, A K BECKtE G BERNSTINE et al, 1989 REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. J Bacteriol 171: 5659-5667.
24. MORRISON, A, A L JOHNSON, L H JOHNSTON and A SUGINO, 1993 Pathway correcting DNA replication errors in Saccharomyces cerevisiae. EMBOJ 12: 1467-1473.
25. MORROW, D M, D A TAGLE, Y SHILOH, F S COLLINS and P HIETER, 1995 TEL1, an S cerevisiae homologue of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82: 831-840.
26. MURRAY, A W, 1995 The genetics of cell cycle checkpoints. Curr Opin Genet Dev 5: 5-11.
27. NAEGELI, H, 1994 Roadblocks and detours during DNA replication: mechanisms of mutagenesis in mammalian cells. Bioessays 16: 557-564.
28. NAVAS, T A, Z ZHOU and S J ELLEDGE, 1995 DNA Polymerase ε links the DNA replication machinery to the S phase checkpoint. Cell 80: 29-39.
29. NELSON, J R, C W LAWRENCE and D C HINKLE, 1996. Thymine-. thymine dimer bypass by yeast DNA poI)Tnerase z Science 272: 1646-1649.
30. NICIIOLS, A F, and A SANCAR, 1992 Purification of PCNA as a nucleotide excision repair protein. Nucleic Acids Res 20: 2441-2446.
31. OSTROFF, R M, and R A SCLAFANI, 1995 Cell cycle regulation of induced mutagenesis in yeast. Mutat Res 329: 143-152.
32. PAINTER, R B, and B R YOUNG, 1980 Radiosensitivity in ataxiatelangiectasia: a new explanation. Proc Nad Acad Sei USA 77: 7315-7317.
33. PAULOVICH, A G, and L H HARTWEU, 1995 A checkpoint regulates the rate of progression through S phase in S cerevisiae in response to DNA damage. Cell 82: 841-847.
34. POPOFF, S C, A I SPIRA, A WJOHNSON and B DEMPLE, 1990 Yeast structural gene (APNI) for the major apurinic endonuclease: homolog)' to Escherichia coli endonuclease IV. Proc Nail Acad Sei USA 87: 4193-4197.
35. RAMOTAR, D, S C POPOFF, E B GRALiAand B DEMPIE, 1991 Cellular role of yeast Apnl apurinic endonuclease/3′-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol Cell Biol 11: 4537-4544.
36. REYNOLDS, A E, R M MCCARROLL, C S NEWLON and W L FANGMAN, 1989 Time of replication of ARS elements along yeast chromosome III. Mol Cell Biol 9: 4488-4494.
37. ROTHSTEIN, RJ, 1983 One-step gene disruption in yeast. Methods Enzymol 101: 202-211.
38. ROWLEY, R, S SUBRAMANI and P G YOUNG, 1992 Checkpoint controls in Schhosaccharomycespombe: radl. EMBOJ II: 1335-1342.
39. SAMSON, L, J THOMALE and M F RAJEWSKY, 1988 Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair. EMBOJ 7: 2261-2267.
40. SANCIIEZ, Y, BA DESANY, WJJONES, Q Liu, B WANG et al, 1996 Regulation of RAD53 by the ATOHike kinases MECI and TEL1 in yeast cell cycle checkpoint pathways. Science 271: 357-360.
41. SAVTTSKY, K, A BAR-SIIIRA, S GiLAD, G RoTMAN, Y Ziv et al, 1995a A single ataxia telangiectasia gene wirii a product similar to PI-3 kinase. Science 268: 1749-1753.
42. SAVTTSKY, K, S SFEZ, D A TAGIE, Y ZiV, A SARTIEL et al, 1995b The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum Mol Genet 4: 2025-2032.
43. SCHILD, D, BJ GLASSNER, R K MORTIMER, M CARLSON and B C LAURENT, 1992 Identification of RAD16, a yeast excision repair gene homologous to the recombinational repair gene RAD54 and to the SAT2gene involved in transcriptional activation. Yeast 8: 385-395.
44. SHERMAN, F, G R FINK andj B HICKS, 1981 Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
45. SHIVJI, K K, M K KENNT and R D WOOD, 1992 Proliferating cell nuclear antigen is required for DNA excision repair. Cell 69: 367-374.
46. SIEDE, W, A S FRIEDBERG and E C FRIEDBERG, 1993 RAD9-dependent Gl arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae. Proc Nad Acad Sei USA 90: 7985-7989.
47. SIEDE, W, A S FRJEDBERG, I DIANOVA and E C FRIEDBERG, 1994 Characterization of Gl checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents. Genetics 138: 271-281.
48. SIKORSKI, R S, and P HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
49. SINGER, B, and D GRUNBERGER, 1983 Molecular Biology ofMutagens and Carcinogens. Plenum Press, New York.
50. SMERDON, M J, and F TIIOMA, 1990 Site-specific DNA repair at the nucleosome level in a yeast minichromosome. Cell 61: 675-684.
51. SUTDER, K S, and P C HANAWALT, 1992 Preferential repair of qclobutane dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription. Proc Nad Acad Sei USA 89: 10696-10700.
52. SWEDER, K S, and P C HANAWALT, 1994 The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269: 1852-1857.
53. VAN GOOL, A. J, R VERHAGE, S M A SWAGEJLAKERS, P VAN DE PUTTE,. J BROUWER et al, 1994 RAD26, the functional S cerevisiaehomologue of the Cockayne syndrome B gene ERCC6. EMBO J 13: 53G1-5369.
54. VOIGT, J M, B VAN HOUTEN and M D TOPAL, 1989 Repair of O6methylguanine by ABC exinuclease of Escherichia coli in vitro. J Biol Chem 264: 5172-5176.
55. WEINERT, T A, and L H HARTWELL, 1988 The RADPgene controls the cell cycle response to DMA damage in Saccharomyces cerevisiae. Science 241: 317-322.
56. WEINERT, T A, and L H HARWELL, 1990 Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage. Mol Cell Biol 10: G554-6564.
57. WEINFRT, T A, and L H HARWELL, 1993 Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134: 63-80.
58. WEINERT, T A, G L KISER and L H HARWELL, 1994 Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8: 652-665.
59. XIAO, W, B DERFIER, J CHEN and L SAMSON, 1991 Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylth)Tnine DN'A repair methyltransferase gene. EMBO J 10: 2179-2186.
60. YAMAMOTO, A, V GUACCI and D KOSIIIAND, 1996a Pdslp is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J Cell Biol 133: 85-97.
61. YAMAMOTO, A, V GUACCI and D KOSIIIAND, 199Gb Pdslp, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathways. J Cell Biol 133: 99-110.
62. YARBRO, J W, 1992 Mechanism of action of hydroxyurea. Semin Oncol 19 (Suppl 9): 1-10.
63. YOUNG, B R, and R B PAINTER, 1989 Radioresistant DNA synthesis and human genetic diseases. Hum Genet 82: 113-117.
64. ZHOU, Z, and SJ EILEDGE, 1993 DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell 75: 1119-1127.