Effects of mutations of RAD50, RAD51, RAD52, and related genes on illegitimate recombination in Saccharomyces cerevisiae

Genetics

Volumn 142, Issue 2, 1996, Pages 383-391

  Tsukamoto, Yasumasa ^a   Kato, Jun Ichi ^a   Ikeda, Hideo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CANAVANINE; CYCLOHEXIMIDE;

ARTICLE; GENE; GENE MUTATION; GENETIC RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; RECOMBINANT PLASMID; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

BASE SEQUENCE; DNA PRIMERS; DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; FUNGAL PROTEINS; GENE DELETION; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; PLASMIDS; RAD51 RECOMBINASE; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0030031522     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (67)

1. ABOUSSEKHRA, A., R. CHANET, A. ADJIRi and F. FABRE, 1992 Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. Mol. Cell. Biol. 12: 3224-3234.
2. ADZUMA, K, T. OGAWA and H. OGAWA, 1984 Primary structure of the RAD52 gene in Saccharomyces cerevisiae. Mol. Cell. Biol. 4: 2735-2744.
3. AJIMURA, M., S.-H. LEEM and H. OGAWA, 1992 Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics 133: 51-66.
4. ALANI, E., L. CAO and N. KLECKNER, 1987 A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116: 541-545.
5. ALANI, E., S SUBBIAH and N. KLECKNER, 1989 The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions. Genetics 122: 47-57.
6. ALANI, E., R. PADMORE and N. KLECKNER, 1990 Analysis of wild-type and md50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell 61: 419-436.
7. ALBERTINI, A. M., M. HOFER, M. P. CALOS and J. H. MILLER, 1982 On the formation of spontaneous deletions: the importance of short sequences homologies in the generation of large deletions. Cell 29: 319-328.
8. ALLGOOD, N D., and T. J. SILHAVY, 1988 Illegitimate recombination in bacteria, pp. 309-330 in Genetic Recombination, edited by R. KUCHERLAPATI and G. R. SMITH. American Society for Microbiology, Washington, DC.
9. ALLGOOD, N. D., and T. J. SILHAVY. 1991 Escherichia coli xonA (sbcB) mutants enhance illegitimate recombination. Genetics 127: 671-680.
10. BASILE, G., M. AKER and R. K. MORTIMER, 1992 Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51. Mol. Cell. Biol. 12: 3235-3246.
11. BISHOP, D. K., D. PARK, L. Xu and N. KLECKNER, 1992 DMCI: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69: 439-456.
12. BROWN, P. A., and J. W. SZOSTAK, 1983 Yeast vectors with negative selection. Methods Enzymol. 101: 278-290.
13. CHOW, T. Y.-K., and M. A. RESNICK, 1987 Purification and characterization of an endo-exonuclease from Saccharomyces cerevisiae that is influenced by the RAD52 gene. J. Biol. Chem. 262: 17659-17667.
14. CHOW, T. Y.-K., and M. A. RESNICK, 1988 An endo-exonuclease activity of yeast that requires a functional RAD52 gene. Mol. Gen. Genet. 211: 41-48.
15. COUKELL, M. B., and C. YANOFSKY, 1971 Influence of chromosome structure on the frequency of tonB trp deletions in Eschrichia coli. J. Bacteriol. 105: 864-872.
16. EHRLICH, S. D., 1989 Illegitimate recombination in bacteria, pp. 799-832 in Mobile DNA, edited by D. E. BERG and M. M. HOWE. American Society for Microbiology, Washington, DC.
17. EKWALL, K., and T. RUUSALA, 1991 Budding yeast CAN1 gene as a selection marker in fission yeast. Nucleic Acids Res. 19: 1150.
18. + function. Genetics 55: 699-707.
19. GRANT, S. G. N., J. JESSEE, F. R. BLOOM and D. HANAHAN, 1990 Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants. Proc. Natl. Acad. Sci. USA 87: 4645-4649.
20. IKEDA, H., H. SHIMIZU, T. UKITA and M KUMAGAI, 1995 A novel assay for illegitimate recombination in Escherichia coli. stimulation of λKo transducing phage formation by ultraviolet light and its independence from RecA function. Adv. Biophys. 31: 197-208.
21. INSELBRUC, J., 1967 Formation of deletion mutations in recombination-deficient mutants of Eschrichia coli. J. Bacteriol. 94: 1266-1267.
22. ITO, H., Y. FUKUDA, K. MURATA and A. KIMURA, 1983 Transformation of intact yeast cells treated with alkaline cations. J. Bacteriol. 153: 163-168.
23. IVANOV, E L., V. G. KOROLEV and F. FABRE, 1992 XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics 132: 651-664.
24. IVANOV, E. L., N. SUGAWARA, C. I. WHITE, F. FABRE and J. E. HABER, 1994 Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol. Cell. Biol. 14: 3414-3425.
25. JOHZUKA, K., and H. OGAWA, 1995 Interaction of Mre11 and Rad50: Two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics 139: 1521-1532.
26. KANS, J. A., and R. K. MORTIMER, 1991 Nucleotide sequence of the RAD57 gene of Saccharomyces cerevisiae. Gene 105: 139-140.
27. KLEIN, H. L., 1988 Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae. Genetics 120: 367-377.
28. KRAMER, K M., J. A. BROCK, K. BLOOM, J K. MOORE and J. E. HABER, 1994 Two different types of double-strand breaks in Saccharomyces cerevisiae are required by similar RAD52-independent, nonhomologous recombination events. Mol. Cell. Biol. 14: 1293-1301.
29. KUMAGAI, M., and H. IKEDA, 1991 Molecular analysis of the recombination junctions of λbio transducing phages. Mol. Gen. Genet. 230: 60-64.
30. LEA, D. E., and C. A. COUISON, 1948 The distribution of the numbers of mutants in bacterial populations. J. Genet. 49: 264-284.
31. LOVETT, S. T., 1994 Sequence of the RAD55 gene of Saccharomyces cerevisiae: similarity of RAD55 to prokaryotic RecA and other RecA-like proteins. Gene 142: 103-106.
32. LOVETT, S. T., and R. K. MORTIMER, 1987 Characterization of null mutants of the RAD55 gene of Saccharomyces cerevisiae: effects of temperature, osmotic strength and mating type. Genetics 116: 547-553.
33. LURIA, S. E., and M. DELBRUCK, 1943 Mutations of bacteria from virus sensitivity to virus resistance. Genetics 28: 491-511.
34. MALONE, R. E., 1983 Multiple mutant analysis of recombination in yeast. Mol. Gen. Genet. 189: 405-412.
35. MALONE, R. E., T. WARD, S. LIN and J. WARING, 1990 The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast. Curr. Genet. 18: 111-116.
36. MCDONALD, J. P., and R. ROTHSTEIN, 1994 Unrepaired heteroduplex DNA in Saccharomyces cerevisiae. is decreased in RAD1 RAD52-independent recombination. Genetics 137: 393-405.
37. MEUTH, M., 1989 Illegitimate recombination in mammalian cells, pp. 833-860 in Mobile DNA, edited by D. E. BERG and M. M. HOWE American Society for Microbiology, Washington, DC.
38. MILNE, G. T., and D. T. WEAVER, 1993 Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52. Genes Dev. 7: 1755-1765.
39. NAKAYAMA, N., A. MIYAJIMA and K. ARAI, 1985 Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae. EMBO J. 4: 2643-2648.
40. NORTH, P., A. GANESH and J. THACKER, 1990 The rejoining of double-strand breaks in DNA by human cell extracts. Nucleic Acids Res. 18: 6205-6210.
41. OGAWA, T., A. SIHNOHARA, A. NABETANI, T. IKEYA, X. Yu et al., 1993a RecA-like recombination proteins in eukaryotes: functions and structures of RAD51 genes. Cold Spring Harbor Symp. Quant. Biol. 58: 567-576.
42. OGAWA, T., X. Yu, A. SHINOHARA and E. H. EGELMAN, 1993b Similarity of the yeast RAD51 filament to the bacterial RecA filament. Science 259: 1896-1899.
43. ORR-WEAVER, T. L., and J. W. SZOSTAK, 1983 Yeast recombination: the association between double-strand gap repair and crossing-over. Proc. Natl. Acad. Sci. USA 80: 4417-4421.
44. ORR-WEAVER, T. L., J. W. SZOSTAK and R. J. ROTHSTEIN, 1981 Yeast transformation, a model system for the study of recombination. Proc. Natl. Acad. Sci. USA 78: 6354-6358.
45. PETES, T. D., R. E. MALONE and L. S. SYMINGTON, 1991 Recombination in yeast, pp. 407-521 in The Molecular and Cellular Biology of the Yeast Saccharomyces. Genome Dynamics, Protein Synthesis and Energetics, Vol. 1, edited by J. R. BROACH, J. R. PRINGLE and E. W. JONES. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
46. RATTRAY, A. J., and L. S. SYMINGTON, 1994 Use of a chromosomal inverted repeat to demonstrate that the RAD51 and RAD52 genes of Saccharomyces cerevisiae have different roles in mitotic recombination. Genetics 138: 587-595.
47. RESNICK, M. A., A. SUGINO, J. NITISS and T. CHOW, 1984 DNA polymerases, deoxyribonucleases, and recombination during meiosis in Saccharomyces cerevisiae. Mol. Cell. Biol. 4: 2811-2817.
48. REYNOLDS, P., L. PRAKASH and S. PRAKASH, 1987 Nucleotide sequence and functional analysis of the RAD1 gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 7: 1012-1020.
49. ROSE, M. D., F. WINSTON and P. HIETER, 1990 Methods in Yeast Genetics. A Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
50. ROTH, D. B., and J. H. WILSON, 1986 Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6: 4295-4304.
51. ROTH, D. B., T. N. PORTER and J. H. WILSON, 1985 Mechanism of nonhomologous recombination in mammalian cells. Mol. Cell. Biol. 5: 2599-2607.
52. ROTUSTEIN, R. J., 1983 One-step gene disruption in yeast. Methods Enzymol. 101: 202-211.
53. SAEKI, T., I. MACHIDA and S. NAKAI, 1980 Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiae. Mutat. Res. 73: 251-265.
54. SAMBROOK, J., E F. FRITSCH and T. MANIATIS, 1989 Molecular Cloning: A Laboratory Manual, Ed. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
55. SCHIESTL, R. H., and T. D PETES. 1991 Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 88: 7585-7589.
56. SCHIESTI., R. H., and S. PRAKASH, 1988 RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination. Mol. Cell. Biol. 8: 3619-3626.
57. SCHIESTI., R. H , M. DOMINSKA and T. D. PETES, 1993 Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. Mol. Cell. Biol. 13: 2697-2705.
58. SCHIESTI., R. H., J. ZHU and T. D. PETES, 1994 Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 14: 4493-4500.
59. SHIMIZU, H , H. YAMAGUCHI and H. IKEDA, 1995 Molecular analysis of λbio transducing phage produced by oxolinic acid-induced illegitimate recombination in vivo. Genetics 140: 889-896.
60. SHINOHARA, A., H. OGAWA and T. OGAWA, 1992 Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 69: 457-470.
61. SUGAWARA, N., and J. E. HABER, 1992 Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol. Cell. Biol. 12: 563-575.
62. SUGAWARA, N., E. L. IVANOV, J. FISHMAN-LOBELL, B. L. RAY, X Wu et al., 1995 DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature 373: 84-86.
63. SUNG, P., 1994 Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein. Science 265: 1241-1243.
64. SZOSTAK, J. W., T. L. ORR-WEAVER and K.J. ROTHSTEIN, 1983 The double-strand-break repair model for recombination. Cell 33: 25-35.
65. THOMAS, B. J., and R. ROTHSTEIN, 1989 The genetic control of direct-repeat recombination in Saccharomyces: the effect of rad52 and rad1 on mitotic recombination at GAL10, a transcriptionally regulated gene. Genetics 123: 725-738
66. VIEIRA, J., and J. MESSING, 1987 Production of single-stranded plasmid DNA. Meth. Enzymol. 153: 3-11.
67. YAMAGUCHI, H., T. YAMASHITA, H. SHIMIZU and H. IKEDA, 1995 A hotspot of spontaneous and UV-induced illegitimate recombination during formation of λbio transducing phage. Mol. Gen. Genet. (In press).