Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing

Journal of Biological Chemistry

Volumn 274, Issue 20, 1999, Pages 13818-13823

  Saura, Carlos A ^a   Tomita, Taisuke ^b   Davenport, Frances ^a   Harris, Christie L ^a   Iwatsubo, Takeshi ^b   Thinakaran, Gopal ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE MUTATION; MOLECULAR INTERACTION; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

ALZHEIMER DISEASE; ANIMALS; BINDING SITES; COS CELLS; FLAVIN-ADENINE DINUCLEOTIDE; HUMANS; MEMBRANE PROTEINS; MICE; PRESENILIN-1; PRESENILIN-2; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSGENES; TUMOR CELLS, CULTURED;

EID: 0033553564     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.20.13818     Document Type: Article

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